Standard
eTRANSAFE : data science to empower translational safety assessment. / Sanz, Ferran; Pognan, François; Steger-Hartmann, Thomas; Díaz, Carlos; Asakura, Shoji; Amberg, Alexander; Bécourt-Lhote, Nathalie; Blomberg, Niklas; Bosc, Nicolas; Briggs, Katharine; Bringezu, Frank; Brulle-Wohlhueter, Claire; Brunak, Søren; Bueters, Ruud; Callegaro, Giulia; Capella-Gutierrez, Salvador; Centeno, Emilio; Corvi, Javier; Cronin, Mark T.D.; Drew, Philip; Duchateau-Nguyen, Guillemette; Ecker, Gerhard F.; Escher, Sylvia; Felix, Eloy; Ferreiro, Miguel; Frericks, Markus; Furlong, Laura I.; Geiger, Robert; George, Catherine; Grandits, Melanie; Ivanov-Draganov, Dragomir; Kilgour-Christie, Jean; Kiziloren, Tevfik; Kors, Jan A.; Koyama, Naoki; Kreuchwig, Annika; Leach, Andrew R.; Mayer, Miguel Angel; Monecke, Peter; Muster, Wolfgang; Nakazawa, Chihiro Miyamoto; Nicholson, Gavin; Parry, Rowan; Pastor, Manuel; Piñero, Janet; Oberhauser, Nils; Ramírez-Anguita, Juan Manuel; Rodrigo, Adrián; Smajic, Aljosa; Schaefer, Markus; Schieferdecker, Sebastian; Soininen, Inari; Terricabras, Emma; Trairatphisan, Panuwat; Turner, Sean C.; Valencia, Alfonso; van de Water, Bob; van der Lei, Johan L.; van Mulligen, Erik M.; Vock, Esther; Wilkinson, David.
In:
Nature Reviews Drug Discovery, Vol. 22, No. 8, 2023, p. 605-606.
Research output: Contribution to journal › Comment/debate › Research
Harvard
Sanz, F, Pognan, F, Steger-Hartmann, T, Díaz, C, Asakura, S, Amberg, A, Bécourt-Lhote, N, Blomberg, N, Bosc, N, Briggs, K, Bringezu, F, Brulle-Wohlhueter, C
, Brunak, S, Bueters, R, Callegaro, G, Capella-Gutierrez, S, Centeno, E, Corvi, J, Cronin, MTD, Drew, P, Duchateau-Nguyen, G, Ecker, GF, Escher, S, Felix, E, Ferreiro, M, Frericks, M, Furlong, LI, Geiger, R, George, C, Grandits, M, Ivanov-Draganov, D, Kilgour-Christie, J, Kiziloren, T, Kors, JA, Koyama, N, Kreuchwig, A, Leach, AR, Mayer, MA, Monecke, P, Muster, W, Nakazawa, CM, Nicholson, G, Parry, R, Pastor, M, Piñero, J, Oberhauser, N, Ramírez-Anguita, JM, Rodrigo, A, Smajic, A, Schaefer, M, Schieferdecker, S, Soininen, I, Terricabras, E, Trairatphisan, P, Turner, SC, Valencia, A, van de Water, B, van der Lei, JL, van Mulligen, EM, Vock, E & Wilkinson, D 2023, '
eTRANSAFE: data science to empower translational safety assessment',
Nature Reviews Drug Discovery, vol. 22, no. 8, pp. 605-606.
https://doi.org/10.1038/d41573-023-00099-5APA
Sanz, F., Pognan, F., Steger-Hartmann, T., Díaz, C., Asakura, S., Amberg, A., Bécourt-Lhote, N., Blomberg, N., Bosc, N., Briggs, K., Bringezu, F., Brulle-Wohlhueter, C.
, Brunak, S., Bueters, R., Callegaro, G., Capella-Gutierrez, S., Centeno, E., Corvi, J., Cronin, M. T. D., ... Wilkinson, D. (2023).
eTRANSAFE: data science to empower translational safety assessment.
Nature Reviews Drug Discovery,
22(8), 605-606.
https://doi.org/10.1038/d41573-023-00099-5Vancouver
Sanz F, Pognan F, Steger-Hartmann T, Díaz C, Asakura S, Amberg A et al.
eTRANSAFE: data science to empower translational safety assessment.
Nature Reviews Drug Discovery. 2023;22(8):605-606.
https://doi.org/10.1038/d41573-023-00099-5Author
Sanz, Ferran ; Pognan, François ; Steger-Hartmann, Thomas ; Díaz, Carlos ; Asakura, Shoji ; Amberg, Alexander ; Bécourt-Lhote, Nathalie ; Blomberg, Niklas ; Bosc, Nicolas ; Briggs, Katharine ; Bringezu, Frank ; Brulle-Wohlhueter, Claire ; Brunak, Søren ; Bueters, Ruud ; Callegaro, Giulia ; Capella-Gutierrez, Salvador ; Centeno, Emilio ; Corvi, Javier ; Cronin, Mark T.D. ; Drew, Philip ; Duchateau-Nguyen, Guillemette ; Ecker, Gerhard F. ; Escher, Sylvia ; Felix, Eloy ; Ferreiro, Miguel ; Frericks, Markus ; Furlong, Laura I. ; Geiger, Robert ; George, Catherine ; Grandits, Melanie ; Ivanov-Draganov, Dragomir ; Kilgour-Christie, Jean ; Kiziloren, Tevfik ; Kors, Jan A. ; Koyama, Naoki ; Kreuchwig, Annika ; Leach, Andrew R. ; Mayer, Miguel Angel ; Monecke, Peter ; Muster, Wolfgang ; Nakazawa, Chihiro Miyamoto ; Nicholson, Gavin ; Parry, Rowan ; Pastor, Manuel ; Piñero, Janet ; Oberhauser, Nils ; Ramírez-Anguita, Juan Manuel ; Rodrigo, Adrián ; Smajic, Aljosa ; Schaefer, Markus ; Schieferdecker, Sebastian ; Soininen, Inari ; Terricabras, Emma ; Trairatphisan, Panuwat ; Turner, Sean C. ; Valencia, Alfonso ; van de Water, Bob ; van der Lei, Johan L. ; van Mulligen, Erik M. ; Vock, Esther ; Wilkinson, David. / eTRANSAFE : data science to empower translational safety assessment. In: Nature Reviews Drug Discovery. 2023 ; Vol. 22, No. 8. pp. 605-606.
Bibtex
@article{424ba87b12a1472195a5b778c8ee336b,
title = "eTRANSAFE: data science to empower translational safety assessment",
author = "Ferran Sanz and Fran{\c c}ois Pognan and Thomas Steger-Hartmann and Carlos D{\'i}az and Shoji Asakura and Alexander Amberg and Nathalie B{\'e}court-Lhote and Niklas Blomberg and Nicolas Bosc and Katharine Briggs and Frank Bringezu and Claire Brulle-Wohlhueter and S{\o}ren Brunak and Ruud Bueters and Giulia Callegaro and Salvador Capella-Gutierrez and Emilio Centeno and Javier Corvi and Cronin, {Mark T.D.} and Philip Drew and Guillemette Duchateau-Nguyen and Ecker, {Gerhard F.} and Sylvia Escher and Eloy Felix and Miguel Ferreiro and Markus Frericks and Furlong, {Laura I.} and Robert Geiger and Catherine George and Melanie Grandits and Dragomir Ivanov-Draganov and Jean Kilgour-Christie and Tevfik Kiziloren and Kors, {Jan A.} and Naoki Koyama and Annika Kreuchwig and Leach, {Andrew R.} and Mayer, {Miguel Angel} and Peter Monecke and Wolfgang Muster and Nakazawa, {Chihiro Miyamoto} and Gavin Nicholson and Rowan Parry and Manuel Pastor and Janet Pi{\~n}ero and Nils Oberhauser and Ram{\'i}rez-Anguita, {Juan Manuel} and Adri{\'a}n Rodrigo and Aljosa Smajic and Markus Schaefer and Sebastian Schieferdecker and Inari Soininen and Emma Terricabras and Panuwat Trairatphisan and Turner, {Sean C.} and Alfonso Valencia and {van de Water}, Bob and {van der Lei}, {Johan L.} and {van Mulligen}, {Erik M.} and Esther Vock and David Wilkinson",
note = "Funding Information: Drug safety is not the main domain for competition between pharmaceutical companies, and so it is more feasible to develop collaborative projects in this area. For example, legacy drug safety data may be shared among companies with the aim of improving drug safety assessment. Significant steps forward in this direction were taken by the eTOX and eTRANSAFE projects. The eTOX project , which focused on sharing preclinical toxicological data, was carried out from 2010 to 2017. More recently, the eTRANSAFE project , addressing translational drug safety assessment through integrative knowledge management, has been running from 2017 to 2023. Both projects are part of the Innovative Medicines Initiative (IMI) funded by the European Commission and the European Federation of Pharmaceutical Industries and Associations (EFPIA). Here, we highlight the achievements of the eTRANSAFE initiative and discuss the impact of the tools it has developed. ",
year = "2023",
doi = "10.1038/d41573-023-00099-5",
language = "English",
volume = "22",
pages = "605--606",
journal = "Nature Reviews. Drug Discovery",
issn = "1474-1776",
publisher = "nature publishing group",
number = "8",
}
RIS
TY - JOUR
T1 - eTRANSAFE
T2 - data science to empower translational safety assessment
AU - Sanz, Ferran
AU - Pognan, François
AU - Steger-Hartmann, Thomas
AU - Díaz, Carlos
AU - Asakura, Shoji
AU - Amberg, Alexander
AU - Bécourt-Lhote, Nathalie
AU - Blomberg, Niklas
AU - Bosc, Nicolas
AU - Briggs, Katharine
AU - Bringezu, Frank
AU - Brulle-Wohlhueter, Claire
AU - Brunak, Søren
AU - Bueters, Ruud
AU - Callegaro, Giulia
AU - Capella-Gutierrez, Salvador
AU - Centeno, Emilio
AU - Corvi, Javier
AU - Cronin, Mark T.D.
AU - Drew, Philip
AU - Duchateau-Nguyen, Guillemette
AU - Ecker, Gerhard F.
AU - Escher, Sylvia
AU - Felix, Eloy
AU - Ferreiro, Miguel
AU - Frericks, Markus
AU - Furlong, Laura I.
AU - Geiger, Robert
AU - George, Catherine
AU - Grandits, Melanie
AU - Ivanov-Draganov, Dragomir
AU - Kilgour-Christie, Jean
AU - Kiziloren, Tevfik
AU - Kors, Jan A.
AU - Koyama, Naoki
AU - Kreuchwig, Annika
AU - Leach, Andrew R.
AU - Mayer, Miguel Angel
AU - Monecke, Peter
AU - Muster, Wolfgang
AU - Nakazawa, Chihiro Miyamoto
AU - Nicholson, Gavin
AU - Parry, Rowan
AU - Pastor, Manuel
AU - Piñero, Janet
AU - Oberhauser, Nils
AU - Ramírez-Anguita, Juan Manuel
AU - Rodrigo, Adrián
AU - Smajic, Aljosa
AU - Schaefer, Markus
AU - Schieferdecker, Sebastian
AU - Soininen, Inari
AU - Terricabras, Emma
AU - Trairatphisan, Panuwat
AU - Turner, Sean C.
AU - Valencia, Alfonso
AU - van de Water, Bob
AU - van der Lei, Johan L.
AU - van Mulligen, Erik M.
AU - Vock, Esther
AU - Wilkinson, David
N1 - Funding Information:
Drug safety is not the main domain for competition between pharmaceutical companies, and so it is more feasible to develop collaborative projects in this area. For example, legacy drug safety data may be shared among companies with the aim of improving drug safety assessment. Significant steps forward in this direction were taken by the eTOX and eTRANSAFE projects. The eTOX project , which focused on sharing preclinical toxicological data, was carried out from 2010 to 2017. More recently, the eTRANSAFE project , addressing translational drug safety assessment through integrative knowledge management, has been running from 2017 to 2023. Both projects are part of the Innovative Medicines Initiative (IMI) funded by the European Commission and the European Federation of Pharmaceutical Industries and Associations (EFPIA). Here, we highlight the achievements of the eTRANSAFE initiative and discuss the impact of the tools it has developed.
PY - 2023
Y1 - 2023
U2 - 10.1038/d41573-023-00099-5
DO - 10.1038/d41573-023-00099-5
M3 - Comment/debate
C2 - 37316648
AN - SCOPUS:85161815073
VL - 22
SP - 605
EP - 606
JO - Nature Reviews. Drug Discovery
JF - Nature Reviews. Drug Discovery
SN - 1474-1776
IS - 8
ER -
