A second update on mapping the human genetic architecture of COVID-19

Research output: Contribution to journalComment/debateResearchpeer-review

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A second update on mapping the human genetic architecture of COVID-19. / Kanai, Masahiro; Andrews, Shea; Cordioli, Mattia; Stevens, Christine; Neale, Benjamin M.; Daly, Mark; Ganna, Andrea; Pathak, Gita A.; Ellinghaus, David; Banasik, Karina; Brunak, Søren; Pedersen, Ole Birger; Westergaard, David; Sequeros, Celia Burgos; Nissen, Janna; Feldt-Rasmussen, Ulla; Grønbæk, Kirsten; Ostrowski, Sisse R.; Guindo-Martinez, Marta; Garcia, Sara Mingo; Hjalgrim, Henrik; Admin team lead; Admin team member; Analysis team lead; Analysis team member; Data collection lead; Data collection member; Manuscript analysis team lead; Manuscript analysis team members: Mendelian randomization; Manuscript analysis team members: methods development; Manuscript analysis team members: phenome-wide association study; Manuscript analysis team members: principal component projection, gene prioritization; Project management lead; Scientific communication lead; Scientific communication member; Writing group lead; Writing group member; 23andMe; Adolescent brain and cognitive development study; Analysis group; Armenia_Covid-19hg; Assessment of the influence of clinical, functional, immunological and genetic factors on the severity of the course of coronavirus infection with SARS-CoV-2 and post-COVID syndrome; Avon Longitudinal Study of Parents and Children (ALSPAC); BelCovid; Biobanque Quebec COVID19; BioVU; Bonn Study of COVID-19 Genetics; CGEn HostSeq—Canadian COVID-19 Human Host Genome Sequencing Databank; Colorado Center for Personalized Medicine—CCPM; COMRI/Virology Study; Covid19 Ioannina Biobank; COVID19-Host(a)ge; Covid19hg-CL; Danish COVID-19 Genomic Consortium; Egypt hgCOVID hub; EraCORE; FinnGen; French hgCOVID; GCAT. Genomes For Life; Genes & Health; Genetic influences on severity of COVID-19 illness in Korea; GenOMICC; Genotek COVID-19 study; Helix Exome+ COVID-19 Phenotypes; Host Genetic Factors for COVID-19 Severity and Outcome in Western Indian Population; Host Genetics in COVID Cohorts of Mixed ancestry from Mexico; Japan Coronavirus Taskforce; Japan NCGM-COVID19; Jordan COVID-19 Host Genomics Initiative (JCHGI); Leadership; Lung eQTL Consortium; Mass General Brigham—Host Vulnerability to COVID-19; MexGen-COVID; Pa-COVID-19; Project management group; Project management support; Qatar Genome Program; SARS-CoV-2 and Host Genome sequencing; Scientific communication group; Search for Genomic Markers Predicting the Severity of the response to COVID-19; Spanish COalition to Unlock Research on host GEnetics on COVID-19 (SCOURGE); The Danish Blood Donor Study; The Genetic Predisposition to severe COVID-19; Tirschenreuth Study (TiKoco); UCLA Precision Health COVID-19 Host Genomics Biobank; UK Biobank; Variability in Immune Response Genes and Severity of SARS-CoV-2 Infection (INMUNGEN-CoV2 study); Website development; Writing Group; The COVID-19 Host Genetics Initiative.

In: Nature, Vol. 621, No. 7977, 2023, p. E7-E26.

Research output: Contribution to journalComment/debateResearchpeer-review

Harvard

Kanai, M, Andrews, S, Cordioli, M, Stevens, C, Neale, BM, Daly, M, Ganna, A, Pathak, GA, Ellinghaus, D, Banasik, K, Brunak, S, Pedersen, OB, Westergaard, D, Sequeros, CB, Nissen, J, Feldt-Rasmussen, U, Grønbæk, K, Ostrowski, SR, Guindo-Martinez, M, Garcia, SM, Hjalgrim, H, Admin team lead, Admin team member, Analysis team lead, Analysis team member, Data collection lead, Data collection member, Manuscript analysis team lead, Manuscript analysis team members: Mendelian randomization, Manuscript analysis team members: methods development, Manuscript analysis team members: phenome-wide association study, Manuscript analysis team members: principal component projection, gene prioritization, Project management lead, Scientific communication lead, Scientific communication member, Writing group lead, Writing group member, 23andMe, Adolescent brain and cognitive development study, Analysis group, Armenia_Covid-19hg, Assessment of the influence of clinical, functional, immunological and genetic factors on the severity of the course of coronavirus infection with SARS-CoV-2 and post-COVID syndrome, Avon Longitudinal Study of Parents and Children (ALSPAC), BelCovid, Biobanque Quebec COVID19, BioVU, Bonn Study of COVID-19 Genetics, CGEn HostSeq—Canadian COVID-19 Human Host Genome Sequencing Databank, Colorado Center for Personalized Medicine—CCPM, COMRI/Virology Study, Covid19 Ioannina Biobank, COVID19-Host(a)ge, Covid19hg-CL, Danish COVID-19 Genomic Consortium, Egypt hgCOVID hub, EraCORE, FinnGen, French hgCOVID, GCAT. Genomes For Life, Genes & Health, Genetic influences on severity of COVID-19 illness in Korea, GenOMICC, Genotek COVID-19 study, Helix Exome+ COVID-19 Phenotypes, Host Genetic Factors for COVID-19 Severity and Outcome in Western Indian Population, Host Genetics in COVID Cohorts of Mixed ancestry from Mexico, Japan Coronavirus Taskforce, Japan NCGM-COVID19, Jordan COVID-19 Host Genomics Initiative (JCHGI), Leadership, Lung eQTL Consortium, Mass General Brigham—Host Vulnerability to COVID-19, MexGen-COVID, Pa-COVID-19, Project management group, Project management support, Qatar Genome Program, SARS-CoV-2 and Host Genome sequencing, Scientific communication group, Search for Genomic Markers Predicting the Severity of the response to COVID-19, Spanish COalition to Unlock Research on host GEnetics on COVID-19 (SCOURGE), The Danish Blood Donor Study, The Genetic Predisposition to severe COVID-19, Tirschenreuth Study (TiKoco), UCLA Precision Health COVID-19 Host Genomics Biobank, UK Biobank, Variability in Immune Response Genes and Severity of SARS-CoV-2 Infection (INMUNGEN-CoV2 study), Website development, Writing Group & The COVID-19 Host Genetics Initiative 2023, 'A second update on mapping the human genetic architecture of COVID-19', Nature, vol. 621, no. 7977, pp. E7-E26. https://doi.org/10.1038/s41586-023-06355-3

APA

Kanai, M., Andrews, S., Cordioli, M., Stevens, C., Neale, B. M., Daly, M., Ganna, A., Pathak, G. A., Ellinghaus, D., Banasik, K., Brunak, S., Pedersen, O. B., Westergaard, D., Sequeros, C. B., Nissen, J., Feldt-Rasmussen, U., Grønbæk, K., Ostrowski, S. R., Guindo-Martinez, M., ... The COVID-19 Host Genetics Initiative (2023). A second update on mapping the human genetic architecture of COVID-19. Nature, 621(7977), E7-E26. https://doi.org/10.1038/s41586-023-06355-3

Vancouver

Kanai M, Andrews S, Cordioli M, Stevens C, Neale BM, Daly M et al. A second update on mapping the human genetic architecture of COVID-19. Nature. 2023;621(7977):E7-E26. https://doi.org/10.1038/s41586-023-06355-3

Author

Kanai, Masahiro ; Andrews, Shea ; Cordioli, Mattia ; Stevens, Christine ; Neale, Benjamin M. ; Daly, Mark ; Ganna, Andrea ; Pathak, Gita A. ; Ellinghaus, David ; Banasik, Karina ; Brunak, Søren ; Pedersen, Ole Birger ; Westergaard, David ; Sequeros, Celia Burgos ; Nissen, Janna ; Feldt-Rasmussen, Ulla ; Grønbæk, Kirsten ; Ostrowski, Sisse R. ; Guindo-Martinez, Marta ; Garcia, Sara Mingo ; Hjalgrim, Henrik ; Admin team lead ; Admin team member ; Analysis team lead ; Analysis team member ; Data collection lead ; Data collection member ; Manuscript analysis team lead ; Manuscript analysis team members: Mendelian randomization ; Manuscript analysis team members: methods development ; Manuscript analysis team members: phenome-wide association study ; Manuscript analysis team members: principal component projection, gene prioritization ; Project management lead ; Scientific communication lead ; Scientific communication member ; Writing group lead ; Writing group member ; 23andMe ; Adolescent brain and cognitive development study ; Analysis group ; Armenia_Covid-19hg ; Assessment of the influence of clinical, functional, immunological and genetic factors on the severity of the course of coronavirus infection with SARS-CoV-2 and post-COVID syndrome ; Avon Longitudinal Study of Parents and Children (ALSPAC) ; BelCovid ; Biobanque Quebec COVID19 ; BioVU ; Bonn Study of COVID-19 Genetics ; CGEn HostSeq—Canadian COVID-19 Human Host Genome Sequencing Databank ; Colorado Center for Personalized Medicine—CCPM ; COMRI/Virology Study ; Covid19 Ioannina Biobank ; COVID19-Host(a)ge ; Covid19hg-CL ; Danish COVID-19 Genomic Consortium ; Egypt hgCOVID hub ; EraCORE ; FinnGen ; French hgCOVID ; GCAT. Genomes For Life ; Genes & Health ; Genetic influences on severity of COVID-19 illness in Korea ; GenOMICC ; Genotek COVID-19 study ; Helix Exome+ COVID-19 Phenotypes ; Host Genetic Factors for COVID-19 Severity and Outcome in Western Indian Population ; Host Genetics in COVID Cohorts of Mixed ancestry from Mexico ; Japan Coronavirus Taskforce ; Japan NCGM-COVID19 ; Jordan COVID-19 Host Genomics Initiative (JCHGI) ; Leadership ; Lung eQTL Consortium ; Mass General Brigham—Host Vulnerability to COVID-19 ; MexGen-COVID ; Pa-COVID-19 ; Project management group ; Project management support ; Qatar Genome Program ; SARS-CoV-2 and Host Genome sequencing ; Scientific communication group ; Search for Genomic Markers Predicting the Severity of the response to COVID-19 ; Spanish COalition to Unlock Research on host GEnetics on COVID-19 (SCOURGE) ; The Danish Blood Donor Study ; The Genetic Predisposition to severe COVID-19 ; Tirschenreuth Study (TiKoco) ; UCLA Precision Health COVID-19 Host Genomics Biobank ; UK Biobank ; Variability in Immune Response Genes and Severity of SARS-CoV-2 Infection (INMUNGEN-CoV2 study) ; Website development ; Writing Group ; The COVID-19 Host Genetics Initiative. / A second update on mapping the human genetic architecture of COVID-19. In: Nature. 2023 ; Vol. 621, No. 7977. pp. E7-E26.

Bibtex

@article{3bb0bda8fa324ac2ba8dec63f8f407f4,
title = "A second update on mapping the human genetic architecture of COVID-19",
author = "Masahiro Kanai and Shea Andrews and Mattia Cordioli and Christine Stevens and Neale, {Benjamin M.} and Mark Daly and Andrea Ganna and Pathak, {Gita A.} and David Ellinghaus and Karina Banasik and S{\o}ren Brunak and Pedersen, {Ole Birger} and David Westergaard and Sequeros, {Celia Burgos} and Janna Nissen and Ulla Feldt-Rasmussen and Kirsten Gr{\o}nb{\ae}k and Ostrowski, {Sisse R.} and Marta Guindo-Martinez and Garcia, {Sara Mingo} and Henrik Hjalgrim and {Admin team lead} and {Admin team member} and {Analysis team lead} and {Analysis team member} and {Data collection lead} and {Data collection member} and {Manuscript analysis team lead} and {Manuscript analysis team members: Mendelian randomization} and {Manuscript analysis team members: methods development} and {Manuscript analysis team members: phenome-wide association study} and {Manuscript analysis team members: principal component projection, gene prioritization} and {Project management lead} and {Scientific communication lead} and {Scientific communication member} and {Writing group lead} and {Writing group member} and 23andMe and {Adolescent brain and cognitive development study} and {Analysis group} and Armenia_Covid-19hg and {Assessment of the influence of clinical, functional, immunological and genetic factors on the severity of the course of coronavirus infection with SARS-CoV-2 and post-COVID syndrome} and {Avon Longitudinal Study of Parents and Children (ALSPAC)} and BelCovid and {Biobanque Quebec COVID19} and BioVU and {Bonn Study of COVID-19 Genetics} and {CGEn HostSeq—Canadian COVID-19 Human Host Genome Sequencing Databank} and {Colorado Center for Personalized Medicine—CCPM} and {COMRI/Virology Study} and {Covid19 Ioannina Biobank} and COVID19-Host(a)ge and Covid19hg-CL and {Danish COVID-19 Genomic Consortium} and {Egypt hgCOVID hub} and EraCORE and FinnGen and {French hgCOVID} and {GCAT. Genomes For Life} and {Genes & Health} and {Genetic influences on severity of COVID-19 illness in Korea} and GenOMICC and {Genotek COVID-19 study} and {Helix Exome+ COVID-19 Phenotypes} and {Host Genetic Factors for COVID-19 Severity and Outcome in Western Indian Population} and {Host Genetics in COVID Cohorts of Mixed ancestry from Mexico} and {Japan Coronavirus Taskforce} and {Japan NCGM-COVID19} and {Jordan COVID-19 Host Genomics Initiative (JCHGI)} and Leadership and {Lung eQTL Consortium} and {Mass General Brigham—Host Vulnerability to COVID-19} and MexGen-COVID and Pa-COVID-19 and {Project management group} and {Project management support} and {Qatar Genome Program} and {SARS-CoV-2 and Host Genome sequencing} and {Scientific communication group} and {Search for Genomic Markers Predicting the Severity of the response to COVID-19} and {Spanish COalition to Unlock Research on host GEnetics on COVID-19 (SCOURGE)} and {The Danish Blood Donor Study} and {The Genetic Predisposition to severe COVID-19} and {Tirschenreuth Study (TiKoco)} and {UCLA Precision Health COVID-19 Host Genomics Biobank} and {UK Biobank} and {Variability in Immune Response Genes and Severity of SARS-CoV-2 Infection (INMUNGEN-CoV2 study)} and {Website development} and {Writing Group} and {The COVID-19 Host Genetics Initiative}",
note = "Arising from: COVID-19 Host Genetics Initiative. Nature https://doi.org/10.1038/s41586-021-03767-x (2021)",
year = "2023",
doi = "10.1038/s41586-023-06355-3",
language = "English",
volume = "621",
pages = "E7--E26",
journal = "Nature Genetics",
issn = "1061-4036",
publisher = "nature publishing group",
number = "7977",

}

RIS

TY - JOUR

T1 - A second update on mapping the human genetic architecture of COVID-19

AU - Kanai, Masahiro

AU - Andrews, Shea

AU - Cordioli, Mattia

AU - Stevens, Christine

AU - Neale, Benjamin M.

AU - Daly, Mark

AU - Ganna, Andrea

AU - Pathak, Gita A.

AU - Ellinghaus, David

AU - Banasik, Karina

AU - Brunak, Søren

AU - Pedersen, Ole Birger

AU - Westergaard, David

AU - Sequeros, Celia Burgos

AU - Nissen, Janna

AU - Feldt-Rasmussen, Ulla

AU - Grønbæk, Kirsten

AU - Ostrowski, Sisse R.

AU - Guindo-Martinez, Marta

AU - Garcia, Sara Mingo

AU - Hjalgrim, Henrik

AU - Admin team lead

AU - Admin team member

AU - Analysis team lead

AU - Analysis team member

AU - Data collection lead

AU - Data collection member

AU - Manuscript analysis team lead

AU - Manuscript analysis team members: Mendelian randomization

AU - Manuscript analysis team members: methods development

AU - Manuscript analysis team members: phenome-wide association study

AU - Manuscript analysis team members: principal component projection, gene prioritization

AU - Project management lead

AU - Scientific communication lead

AU - Scientific communication member

AU - Writing group lead

AU - Writing group member

AU - 23andMe

AU - Adolescent brain and cognitive development study

AU - Analysis group

AU - Armenia_Covid-19hg

AU - Assessment of the influence of clinical, functional, immunological and genetic factors on the severity of the course of coronavirus infection with SARS-CoV-2 and post-COVID syndrome

AU - Avon Longitudinal Study of Parents and Children (ALSPAC)

AU - BelCovid

AU - Biobanque Quebec COVID19

AU - BioVU

AU - Bonn Study of COVID-19 Genetics

AU - CGEn HostSeq—Canadian COVID-19 Human Host Genome Sequencing Databank

AU - Colorado Center for Personalized Medicine—CCPM

AU - COMRI/Virology Study

AU - Covid19 Ioannina Biobank

AU - COVID19-Host(a)ge

AU - Covid19hg-CL

AU - Danish COVID-19 Genomic Consortium

AU - Egypt hgCOVID hub

AU - EraCORE

AU - FinnGen

AU - French hgCOVID

AU - GCAT. Genomes For Life

AU - Genes & Health

AU - Genetic influences on severity of COVID-19 illness in Korea

AU - GenOMICC

AU - Genotek COVID-19 study

AU - Helix Exome+ COVID-19 Phenotypes

AU - Host Genetic Factors for COVID-19 Severity and Outcome in Western Indian Population

AU - Host Genetics in COVID Cohorts of Mixed ancestry from Mexico

AU - Japan Coronavirus Taskforce

AU - Japan NCGM-COVID19

AU - Jordan COVID-19 Host Genomics Initiative (JCHGI)

AU - Leadership

AU - Lung eQTL Consortium

AU - Mass General Brigham—Host Vulnerability to COVID-19

AU - MexGen-COVID

AU - Pa-COVID-19

AU - Project management group

AU - Project management support

AU - Qatar Genome Program

AU - SARS-CoV-2 and Host Genome sequencing

AU - Scientific communication group

AU - Search for Genomic Markers Predicting the Severity of the response to COVID-19

AU - Spanish COalition to Unlock Research on host GEnetics on COVID-19 (SCOURGE)

AU - The Danish Blood Donor Study

AU - The Genetic Predisposition to severe COVID-19

AU - Tirschenreuth Study (TiKoco)

AU - UCLA Precision Health COVID-19 Host Genomics Biobank

AU - UK Biobank

AU - Variability in Immune Response Genes and Severity of SARS-CoV-2 Infection (INMUNGEN-CoV2 study)

AU - Website development

AU - Writing Group

AU - The COVID-19 Host Genetics Initiative

N1 - Arising from: COVID-19 Host Genetics Initiative. Nature https://doi.org/10.1038/s41586-021-03767-x (2021)

PY - 2023

Y1 - 2023

U2 - 10.1038/s41586-023-06355-3

DO - 10.1038/s41586-023-06355-3

M3 - Comment/debate

C2 - 37674002

AN - SCOPUS:85178660706

VL - 621

SP - E7-E26

JO - Nature Genetics

JF - Nature Genetics

SN - 1061-4036

IS - 7977

ER -

ID: 379590963