A genome-wide association study of men with symptoms of testicular dysgenesis syndrome and its network biology interpretation

Research output: Contribution to journalJournal articleResearchpeer-review

  • Marlene D. Dalgaard
  • Nils Weinhold
  • Daniel Edsgärd
  • Jeremy David Silver
  • Tune H. Pers
  • John E. Nielsen
  • Niels Jørgensen
  • Aleksander Giwercman
  • Yvonne L. Giwercman
  • Gabriella Cohn-Cedermark
  • Helena E. Virtanen
  • Jorma Toppari
  • Gedske Daugaard
  • Thomas Skøt Jensen
  • Ewa Rajpert-De Meyts
  • Niels E. Skakkebæk
  • Henrik Leffers
  • Ramneek Gupta
Testicular dysgenesis syndrome (TDS) is a common disease that links testicular germ cell cancer, cryptorchidism and some cases of hypospadias and male infertility with impaired development of the testis. The incidence of these disorders has increased over the last few decades, and testicular cancer now affects 1% of the Danish and Norwegian male population.
Original languageEnglish
JournalJournal of Medical Genetics
Issue number1
Pages (from-to)58-65
Number of pages8
Publication statusPublished - 2012

    Research areas

  • Adult, Bone Morphogenetic Protein 7, Case-Control Studies, Cohort Studies, Gene Expression, Genetic Markers, Genetic Predisposition to Disease, Genome-Wide Association Study, Genotype, Gonadal Dysgenesis, Humans, Linkage Disequilibrium, Male, Neoplasms, Germ Cell and Embryonal, Polymorphism, Single Nucleotide, Protein Interaction Maps, Proteoglycans, Receptors, Transforming Growth Factor beta, Stem Cell Factor, Testicular Neoplasms, Testis

ID: 40167224