Søren Brunak
Professor
Brunak Group
Blegdamsvej 3B
2200 København N
Legacy data sharing to improve drug safety assessment: the eTOX project
Sanz, F., Pognan, F., Steger-Hartmann, T., Díaz, C., Cases, M., Pastor, M., Marc, P., Wichard, J., Briggs, K., Watson, D. K., Kleinöder, T., Yang, C., Amberg, A., Beaumont, M., Brookes, A. J., Brunak, S., Cronin, M. T. D., Ecker, G. F., Escher, S., Greene, N. & 17 others, , Dec 2017, In: Nature Reviews. Drug Discovery. 16, 12, p. 811-812 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Author Correction: Leveraging European infrastructures to access 1 million human genomes by 2022
Saunders, G., Baudis, M., Becker, R., Beltran, S., Béroud, C., Birney, E., Brooksbank, C., Brunak, S., Van den Bulcke, M., Drysdale, R., Capella-Gutierrez, S., Flicek, P., Florindi, F., Goodhand, P., Gut, I., Heringa, J., Holub, P., Hooyberghs, J., Juty, N., Keane, T. M. & 21 others, , Nov 2019, In: Nature Reviews. Genetics. 20, 11, p. 702Research output: Contribution to journal › Comment/debate › Research
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Leveraging European infrastructures to access 1 million human genomes by 2022
Saunders, G., Baudis, M., Becker, R., Beltran, S., Béroud, C., Birney, E., Brooksbank, C., Brunak, S., Van den Bulcke, M., Drysdale, R., Capella-Gutierrez, S., Flicek, P., Florindi, F., Goodhand, P., Gut, I., Heringa, J., Holub, P., Hooyberghs, J., Juty, N., Keane, T. M. & 21 others, , 2019, In: Nature Reviews. Genetics. 20, p. 693-701 9 p.Research output: Contribution to journal › Review › Research › peer-review
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High-throughput sequencing of circulating plasma microRNAs in newly diagnosed type 1 diabetes identifies four different patient clusters
Sebastiani, G., Grieco, G. E., Fignani, D., Chmura, Piotr Jaroslaw, Brorsson, C. A., Bruggraber, S., Pugliese, A., Evans-Molina, C., Knip, M., Peakman, M., Schulte, A. M., Brunak, Søren, Dunger, D. B., Mathieu, C. & Dotta, F., 2020, In: Diabetologia. 63, Suppl. 1, p. S160 1 p.Research output: Contribution to journal › Conference abstract in journal › Research
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A genome-wide association study of social trust in 33,882 Danish blood donors
Sequeros, C. B., Hansen, T. F., Westergaard, D., Louloudis, I., Kalamajski, S., Röder, T., Rohde, P. D., Schwinn, M., Clemmensen, L. H., Didriksen, M., Nyegaard, M., Hjalgrim, H., Nielsen, K. R., Bruun, M. T., Ostrowski, S. R., Erikstrup, C., Mikkelsen, S., Sørensen, E., Pedersen, O. B. V., Brunak, S. & 3 others, , 2024, In: Scientific Reports. 14, 12 p., 1402.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Combined burden and functional impact tests for cancer driver discovery using DriverPower
Shuai, S., Abascal, F., Amin, S. B., Bader, G. D., Bandopadhayay, P., Barenboim, J., Beroukhim, R., Bertl, J., Boroevich, K. A., Brunak, S., Campbell, P. J., Carlevaro-Fita, J., Chakravarty, D., Chan, C. W. Y., Chen, K., Choi, J. K., Deu-Pons, J., Dhingra, P., Diamanti, K., Feuerbach, L. & 32 others, , 2020, In: Nature Communications. 11, 1, 12 p., 734.Research output: Contribution to journal › Journal article › Research › peer-review
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Accurate genotyping across variant classes and lengths using variant graphs
Sibbesen, Jonas Andreas, Maretty, L., Krogh, Anders, Petersen, Bent, Sibbesen, Jonas Andreas, Liu, S., Have, C. T., Bork-Jensen, J., Guo, X., Hansen, Torben, Krogh, Anders, Sørensen, Thorkild I.A., Pedersen, Oluf Borbye, Wang, J. & Brunak, Søren, 2018, In: Nature Genetics. 50, p. 1054-1059 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Disease trajectory browser for exploring temporal, population-wide disease progression patterns in 7.2 million Danish patients
Siggaard, T., Reguant, R., Jørgensen, Isabella Friis, Haue, Amalie Dahl, Lademann, M., Aguayo-Orozco, A., Hjaltelin, Jessica Xin, Jensen, A. B., Banasik, Karina & Brunak, Søren, 2020, In: Nature Communications. 11, 1, 10 p., 4952.Research output: Contribution to journal › Journal article › Research › peer-review
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Deep integrative models for large-scale human genomics
Sigurdsson, Arnór Ingi, Louloudis, Ioannis, Banasik, Karina, Westergaard, D., Winther, Ole, Lund, O., Ostrowski, Sisse Rye, Erikstrup, C., Pedersen, Ole Birger Vesterager, Nyegaard, Mette, Brunak, Søren, Vilhjálmsson, B. & Rasmussen, Simon, 2023, In: Nucleic Acids Symposium Series. 51, 12, 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Analysis of 62 hybrid assembled human Y chromosomes exposes rapid structural changes and high rates of gene conversion
Skov, L., Schierup, M. H., Danish Pan Genome Consortium, D. P. G. C., Sørensen, L. M., Petersen, Bent, Sibbesen, Jonas Andreas, Liu, S., Belling, K. G., Have, C. T., Bork-Jensen, J., Hansen, Torben, Krogh, Anders, Sørensen, Thorkild I.A., Pedersen, Oluf Borbye, Rasmussen, Simon, Kristiansen, Karsten & Brunak, Søren, 2017, In: PLOS Genetics. 13, 8, p. e1006834Research output: Contribution to journal › Journal article › Research › peer-review
The atlas visualisation of genome-wide information
Skovgaard, M., Jensen, L. J., Friis, C., Stærfeldt, H. H., Worning, P., Brunak, Søren & Ussery, D. W., 2002, Methods in Microbiology. Vol. 33. p. 49-63Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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On the total number of genes and their length distribution in complete microbial genomes
Skovgaard, M., Jensen, Lars Juhl, Brunak, Søren, Ussery, D. & Krogh, Anders, 2001, In: Trends in Genetics. 17, 8, p. 425-8 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GWAS meta-analysis reveals key risk loci in essential tremor pathogenesis
Estonian Biobank, E. B. & DBDS Genomic Consortium, D. G. C., 2024, In: Communications Biology . 7, 1, 10 p., 504.Research output: Contribution to journal › Journal article › Research › peer-review
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A genome-wide meta-analysis identifies 50 genetic loci associated with carpal tunnel syndrome
Skuladottir, A. T., Bjornsdottir, G., Ferkingstad, E., Einarsson, G., Stefansdottir, L., Nawaz, M. S., Oddsson, A., Olafsdottir, T. A., Saevarsdottir, S., Walters, G. B., Magnusson, S. H., Bjornsdottir, A., Sveinsson, O. A., Vikingsson, A., Hansen, T. F., Jacobsen, R. L., Erikstrup, C., Schwinn, M., Brunak, S., Banasik, K. & 11 others, , 2022, In: Nature Communications. 13, 1, 9 p., 1598.Research output: Contribution to journal › Journal article › Research › peer-review
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Identification of biomarkers for glycaemic deterioration in type 2 diabetes
Slieker, R. C., Donnelly, L. A., Akalestou, E., Lopez-Noriega, L., Melhem, R., Güneş, A., Abou Azar, F., Efanov, A., Georgiadou, E., Muniangi-Muhitu, H., Sheikh, M., Giordano, G. N., Åkerlund, M., Ahlqvist, E., Ali, A., Banasik, K., Brunak, S., Barovic, M., Bouland, G. A., Burdet, F. & 46 others, , 2023, In: Nature Communications. 14, 18 p., 2533.Research output: Contribution to journal › Journal article › Research › peer-review
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Complex effects of sequence variants on lipid levels and coronary artery disease
Snaebjarnarson, A. S., Helgadottir, A., Arnadottir, G. A., Ivarsdottir, E. V., Thorleifsson, G., Ferkingstad, E., Einarsson, G., Sveinbjornsson, G., Thorgeirsson, T. E., Ulfarsson, M. O., Halldorsson, B. V., Olafsson, I., Erikstrup, C., Pedersen, O. B., Nyegaard, M., Bruun, M. T., Ullum, H., Brunak, S., Iversen, K. K., Christensen, A. H. & 14 others, , 2023, In: Cell. 186, 19, p. 4085-4099.e15Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Analysis of gene expression profiles of microdissected cell populations indicates that testicular carcinoma in situ is an arrested gonocyte
Sonne, Si Brask, Almstrup, Kristian, Dalgaard, M., Juncker, A. S., Edsgard, D., Ruban, L., Harrison, N. J., Schwager, C., Abdollahi, A., Huber, P. E., Brunak, Søren, Gjerdrum, L. M., Moore, H. D., Andrews, P. W., Skakkebæk, Niels Erik, Rajpert-De Meyts, E. & Leffers, H., 15 Jun 2009, In: Current Cancer Research. 69, 12, p. 5241-50 10 p.Research output: Contribution to journal › Journal article › Research
Analysis of cell death inducing compounds
Spicker, J., Pedersen, H. T., Brunak, Søren & Nielsen, H. B., 2007, In: Archives of Toxicology. 81, 11, p. 803-11 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Integration of clinical chemistry, expression, and metabolite data leads to better toxicological class separation
Spicker, J., Brunak, Søren, Frederiksen, K. & Toft, H., 2008, In: Toxicological sciences : an official journal of the Society of Toxicology. 102, 2, p. 444-54 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Complete genes may pass from food to human blood
Spisák, S., Solymosi, N., Ittzés, P., Bodor, A., Kondor, D., Vattay, G., Barták, B. K., Sipos, F., Galamb, O., Tulassay, Z., Szállási, Z., Rasmussen, Simon, Sicheritz-Ponten, T., Brunak, Søren, Molnár, B. & Csabai, I., 2013, In: PloS one. 8, 7, p. e69805Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Endotrophin is associated with chronic multimorbidity and all-cause mortality in a cohort of elderly women
Staunstrup, L. M., Bager, C. L., Frederiksen, P., Helge, Jørn Wulff, Brunak, Søren, Christiansen, C. & Karsdal, M., 2021, In: EBioMedicine. 68, 10 p., 103391.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Precision mapping of the human O-GalNAc glycoproteome through SimpleCell technology
Steentoft, C., Vakhrushev, Sergey, Joshi, Hiren Jitendra, Kong, Y., Vester-Christensen, M. B., Schjoldager, Katrine Ter-Borch Gram, Lavrsen, K., Dabelsteen, Sally, Pedersen, N. B., da Silva, L. P. M., Gupta, R., Bennett, Eric Paul, Mandel, Ulla, Brunak, Søren, Wandall, Hans H., Levery, S. B. & Clausen, Henrik, 15 May 2013, In: E M B O Journal. 32, 10, p. 1478-1488 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- E-pub ahead of print
Variant in the synaptonemal complex protein SYCE2 associates with pregnancy loss through effect on recombination
Steinthorsdottir, V., Halldorsson, B. V., Jonsson, H., Palsson, G., Oddsson, A., Westergaard, D., Arnadottir, G. A., Stefansdottir, L., Banasik, K., Esplin, M. S., Hansen, T. F., Brunak, S., Nyegaard, M., Ostrowski, S. R., Pedersen, O. B. V., Erikstrup, C., Thorleifsson, G., Nadauld, L. D., Haraldsson, A., Steingrimsdottir, T. & 8 others, , 2024, (E-pub ahead of print) In: Nature Structural and Molecular Biology. 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
The cancer exome generated by alternative mRNA splicing dilutes predicted HLA class I epitope density
Stranzl, T., Larsen, M. V., Lund, O., Nielsen, M. & Brunak, Søren, 2012, In: PloS one. 7, 9, p. e38670Research output: Contribution to journal › Journal article › Research › peer-review
- E-pub ahead of print
Obesity variants in the GIPR gene do not associate with risk of fracture or bone mineral density
Styrkarsdottir, U., Tragante, V., Stefansdottir, L., Thorleifsson, G., Oddsson, A., Sørensen, E., Erikstrup, C., Schwarz, Peter, Jørgensen, Henrik Løvendahl, Lauritzen, Jes Bruun, Brunak, Søren, Knowlton, K. U., Nadauld, L. D., Ullum, H., Pedersen, Ole Birger Vesterager, Ostrowski, Sisse Rye, Holm, H., Gudbjartsson, D. F., Sulem, P. & Stefansson, K., 2024, (E-pub ahead of print) In: Journal of Clinical Endocrinology and Metabolism.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 12895347
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Identification of odorant-receptor interactions by global mapping of the human odorome
Research output: Contribution to journal › Journal article › Research › peer-review
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Porcine transcriptome analysis based on 97 non-normalized cDNA libraries and assembly of 1,021,891 expressed sequence tags
Research output: Contribution to journal › Journal article › Research › peer-review
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A human gut microbial gene catalogue established by metagenomic sequencing
Research output: Contribution to journal › Journal article › Research › peer-review
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