David Westergaard

David Westergaard

Assistant Professor

ORCID: 0000-0003-0128-8432

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  1. E-pub ahead of print

    Variant in the synaptonemal complex protein SYCE2 associates with pregnancy loss through effect on recombination

    Steinthorsdottir, V., Halldorsson, B. V., Jonsson, H., Palsson, G., Oddsson, A., Westergaard, D., Arnadottir, G. A., Stefansdottir, L., Banasik, K., Esplin, M. S., Hansen, T. F., Brunak, S., Nyegaard, M., Ostrowski, S. R., Pedersen, O. B. V., Erikstrup, C., Thorleifsson, G., Nadauld, L. D., Haraldsson, A., Steingrimsdottir, T. & 8 others, Tryggvadottir, L., Jonsdottir, I., Gudbjartsson, D. F., Hoffmann, Eva, Sulem, P., Holm, H., Nielsen, Henriette Svarre & Stefansson, K., 2024, (E-pub ahead of print) In: Nature Structural and Molecular Biology. 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Unexplored therapeutic opportunities in the human genome

    Oprea, T. I., Bologa, C. G., Brunak, S., Campbell, A., Gan, G. N., Gaulton, A., Gomez, S. M., Guha, R., Hersey, A., Holmes, J., Jadhav, A., Jensen, L. J., Johnson, G. L., Karlson, A., Leach, A. R., Ma'ayan, A., Malovannaya, A., Mani, S., Mathias, S. L., McManus, M. T. & 21 others, Meehan, T. F., von Mering, C., Muthas, D., Nguyen, D., Overington, J. P., Papadatos, G., Qin, J., Reich, C., Roth, B. L., Schürer, S. C., Simeonov, A., Sklar, L. A., Southall, N., Tomita, S., Tudose, I., Ursu, O., Vidovic, D., Waller, A., Westergaard, David, Yang, J. J. & Zahoránszky-Köhalmi, G., 2018, In: Nature Reviews. Drug Discovery. 17, 5, p. 317-332 16 p.

    Research output: Contribution to journal › Review › Research › peer-review

  3. Published

    The untapped potential of reproductive history in cardiovascular disease

    Bliddal, S., Westergaard, David & Nielsen, Henriette Svarre, 2022, In: European Heart Journal. 43, 3, p. 200-201 2 p.

    Research output: Contribution to journal › Editorial › Research

  4. Published

    The impact of early pregnancy complications on completed family size—A nationwide, registry-based cohort study with 40 years of data

    Kolte, A. M., Westergaard, David, Lidegaard, Øjvind, Brunak, Søren & Nielsen, Henriette Svarre, 2021, In: Acta Obstetricia et Gynecologica Scandinavica. 100, 12, p. 2226-2233

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    The genetic basis of endometriosis and comorbidity with other pain and inflammatory conditions

    Rahmioglu, N., Mortlock, S., Ghiasi, M., Møller, P. L., Stefansdottir, L., Galarneau, G., Turman, C., Danning, R., Law, M. H., Sapkota, Y., Christofidou, P., Skarp, S., Giri, A., Banasik, K., Krassowski, M., Lepamets, M., Marciniak, B., Nõukas, M., Perro, D., Sliz, E. & 35 others, Sobalska-Kwapis, M., Thorleifsson, G., Topbas-Selcuki, N. F., Vitonis, A., Westergaard, David, Arnadottir, R., Burgdorf, Kristoffer Sølvsten, Campbell, A., Cheuk, C. S. K., Clementi, C., Cook, J., De Vivo, I., DiVasta, A., Dorien, O., Donoghue, J. F., Edwards, T., Fontanillas, P., Fung, J. N., Geirsson, R. T., Girling, J. E., Harkki, P., Harris, H. R., Healey, M., Heikinheimo, O., Holdsworth-Carson, S., Hostettler, I. C., Houlden, H., Houshdaran, S., Schork, A. J., Nyegaard, M., DBDS Genomic Consortium, D. G. C., FinnGen Study, F. S., FinnGen Endometriosis Taskforce, F. E. T., Celmatix Research Team, C. R. T. & 23andMe Research Team, 2. R. T., 2023, In: Nature Genetics. 55, 3, p. 423-436 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    TEMPORAL ORDER OF DISEASE PAIRS AFFECTS SUBSEQUENT DISEASE TRAJECTORIES: THE CASE OF DIABETES AND SLEEP APNEA

    Beck, M. K., Westergaard, David, Jensen, A. B., Groop, L. & Brunak, Søren, 2016, In: Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing. 22, p. 380-389 10 p.

    Research output: Contribution to journal › Conference article › Research › peer-review

  7. Published

    Sex differences in text-mined possible adverse drug events associated with drugs for psychosis

    Sørup, Freja Karuna Hemmingsen, Eriksson, R., Westergaard, David, Hallas, J., Brunak, Søren & Andersen, Stig Ejdrup, 2020, In: Journal of Psychopharmacology. 34, 5, p. 532-539 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Antibodies at Delivery in Women, Partners, and Newborns

    Egerup, P., Fich Olsen, L., Christiansen, A-M. H., Westergaard, D., Severinsen, E. R., Hviid, K. V. R., Kolte, A. M., Boje, A. D., Bertelsen, M-L. M. F., Prætorius, L., Zedeler, A., Nielsen, J. R., Bang, D., Berntsen, S., Ethelberg-Findsen, J., Storm, D. M., Bello-Rodríguez, J., Ingham, A., Ollé-López, J., Hoffmann, E. R. & 7 others, Wilken-Jensen, C., Krebs, Lone, Jørgensen, Finn Stener, Westh, Henrik T., Jørgensen, Henrik Løvendahl, Freiesleben, Nina la Cour & Nielsen, Henriette Svarre, 2021, In: Obstetrics and Gynecology. 137, 1, p. 49-55

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Sequencing and de novo assembly of 150 genomes from Denmark as a population reference

    Sørensen, L. M., Jensen, J. M., Petersen, B., Sibbesen, J. A., Liu, S., Villesen, P., Skov, L., Belling, K. G., Have, C. T., Izarzugaza, J. M. G., Grosjean, M., Bork-Jensen, J., Grove, J., Als, T. D., Huang, S., Chang, Y., Xu, R., Ye, W., Rao, J., Guo, X. & 39 others, Sun, J., Cao, H., Ye, C., van Beusekom, J., Espeseth, T., Flindt, E., Friborg, R. M., Halager, A. E., Le Hellard, S., Hultman, C. M., Lescai, F., Li, S., Lund, O., Løngren, P., Mailund, T., Matey-Hernandez, M. L., Mors, O., Pedersen, C. N. S., Sicheritz-Pontén, T., Sullivan, P., Syed, A., Westergaard, David, Yadav, R., Li, N., Xu, X., Hansen, Torben, Krogh, Anders, Bolund, L., Sørensen, Thorkild I.A., Pedersen, Oluf Borbye, Gupta, R., Rasmussen, Simon, Besenbacher, S., Børglum, A. D., Wang, J., Eiberg, Hans Rudolf Lytchoff, Kristiansen, Karsten, Brunak, Søren & Schierup, M. H., 2017, In: Nature. 548, 7665, p. 87-91 5 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  10. Published

    SARS-CoV-2 in first trimester pregnancy: a cohort study

    la Cour Freiesleben, N., Egerup, P., Vauvert Römmelmayer Hviid, K., Rosenbek Severinsen, E., Kolte, A. M., Westergaard, D., Fich Olsen, L., Prætorius, L., Zedeler, A., Hellerung Christiansen, A-M., Reinhardt Nielsen, J., Bang, D., Berntsen, S., Ollé-López, J., Ingham, A., Bello-Rodríguez, J., Marie Storm, D., Ethelberg-Findsen, J., Hoffmann, E. R., Wilken-Jensen, C. & 4 others, Stener Jørgensen, F., Westh, Henrik T., Løvendahl Jørgensen, H. & Nielsen, Henriette Svarre, 2021, In: Human Reproduction. 36, 1, p. 40-47

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Reply of the Authors: Endometriosis and pregnancy loss: the importance of mitigating sources of bias

    Boje, A. D., Egerup, P., Westergaard, David, Mathilde Friis Bertelsen, M. L., Nyegaard, M., Hartwell, D., Lidegaard, Øjvind & Nielsen, Henriette Svarre, 2023, In: Fertility and Sterility. 120, 2, p. 393-394 2 p.

    Research output: Contribution to journal › Letter › Research

  12. Published

    Rare variants with large effects provide functional insights into the pathology of migraine subtypes, with and without aura

    Bjornsdottir, G., Chalmer, M. A., Stefansdottir, L., Skuladottir, A. T., Einarsson, G., Andresdottir, M., Beyter, D., Ferkingstad, E., Gretarsdottir, S., Halldorsson, B. V., Halldorsson, G. H., Helgadottir, A., Helgason, H., Hjorleifsson Eldjarn, G., Jonasdottir, A., Jonasdottir, A., Jonsdottir, I., Knowlton, K. U., Nadauld, L. D., Lund, S. H. & 30 others, Magnusson, O. T., Melsted, P., Moore, K. H. S., Oddsson, A., Olason, P. I., Sigurdsson, A., Banasik, Karina, Brunak, Søren, Didriksen, Maria, Kogelman, L. J. A., Nielsen, K. R., Sørensen, E., Pedersen, Ole Birger Vesterager, Ullum, H., Bay, J., Burgdorf, Kristoffer Sølvsten, Dowsett, J., Hjalgrim, Henrik, Jacobsen, R. L., Louloudis, Ioannis, Lundgaard, Agnete Troen, Mikkelsen, Christina, Nyegaard, Mette, Henriksen, Alexander Pil, Werge, Thomas, Westergaard, David, Olesen, Jes, Ostrowski, Sisse Rye, Hansen, Thomas Folkmann & DBDS Genetic Consortium, D. G. C., 2023, In: Nature Genetics. 55, 11, p. 1843-1853

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Pregnancy-Associated Bleeding and Genetics: Five Sequence Variants in the Myometrium and Progesterone Signaling Pathway are associated with postpartum hemorrhage

    Westergaard, D., Steinthorsdottir, V., Stefansdottir, L., Rohde, P. D., Wu, X., Geller, F., Tyrmi, J., Havulinna, A. S., Navais, P. S., Flatley, C., Ostrowski, S. R., Pedersen, O. B., Erikstrup, C., Sørensen, E., Mikkelsen, C., Brun, M. T., Jensen, B. A., Brodersen, T., Ullum, H., Magnus, P. & 8 others, Andreassen, O. A., Njolstad, P. R., Krebs, Lone, Hansen, Thomas Folkmann, Banasik, Karina, Brunak, Søren, Nielsen, Henriette Svarre & FinnGen, F., 2023, medRxiv, 51 p. (medRxiv).

    Research output: Working paper › Preprint › Research

  14. Published

    Pregnancy outcomes and lifetime fecundity - a nationwide, registry-based cohort study

    Kolte, A. M., Westergaard, David, Lidegaard, Øjvind, Brunak, Søren & Nielsen, Henriette Svarre, 2020, In: Human Reproduction. 35, Suppl. 1, p. i40 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research

  15. Published

    Pregnancy loss is associated with type 2 diabetes: a nationwide case-control study

    Egerup, P., Mikkelsen, A. P., Kolte, A. M., Westergaard, David, Rasmussen, S., Knop, Filip Krag, Lidegaard, Øjvind & Nielsen, Henriette Svarre, 2020, In: Diabetologia. 63, 8, p. 1521-1529

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Pregnancy loss and risk of multiple sclerosis and autoimmune neurological disorder: A nationwide cohort study

    Mikkelsen, A. P., Egerup, P., Kolte, A. M., Westergaard, David, Nielsen, Henriette Svarre & Lidegaard, Øjvind, 2022, In: Plos One. 17, 3, 13 p., e0266203.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Pregnancy Loss and the Risk of Myocardial Infarction, Stroke, and All-Cause Mortality: A Nationwide Partner Comparison Cohort Study

    Mikkelsen, A. P., Egerup, P., Kolte, A. M., Westergaard, David, Torp-Pedersen, Christian, Nielsen, Henriette Svarre & Lidegaard, Øjvind, 2023, In: Journal of the American Heart Association. 12, 15, 17 p., e028620.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Prediction of pancreatic fat and analysis of its determining factors using multi-omics datasets: an IMI DIRECTstudy

    Karaderi, Tugce, Mazzoni, G., Brorsson, C., Westergaard, David, Banasik, Karina, Koivula, R., Thomas, L., Bell, J., Franks, P., Pearson, E. & Brunak, Søren, 2019, In: Diabetologia. 62, p. S166-S166

    Research output: Contribution to journal › Conference abstract in journal › Research

  19. Published

    Population-wide disease trajectories in ischaemic heart disease

    Haue, Amalie Dahl, Jørgensen, Isabella Friis, Christensen, A. H. C., Simon, C. S., Haakonsen, M. L. H., Russo, F. R., Rodriguez, C. L. R., Orozco, A. A. O., Siggard, T. S., Banasik, Karina, Weeke, P. E. W., Westergaard, David, Moseley, P. L. M., Bundgård, Henning & Brunak, Søren, Oct 2019, In: European Heart Journal. 40, S1, p. 1214-1214 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research

  20. Published

    Population-wide analysis of differences in disease progression patterns in men and women

    Westergaard, David, Moseley, P., Sørup, Freja Karuna Hemmingsen, Baldi, P. & Brunak, Søren, 2019, In: Nature Communications. 10, 1, 14 p., 666.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Phenome-Wide Analysis of Short- and Long-Run Disease Incidence Following Recurrent Pregnancy Loss Using Data From a 39-Year Period

    Westergaard, David, Nielsen, A. P., Mortensen, Laust Hvas, Nielsen, Henriette Svarre & Brunak, Søren, 2020, In: Journal of the American Heart Association. 9, 8, 15 p., e015069.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Pancreatic cancer symptom trajectories from Danish registry data and free text in electronic health records

    Hjaltelin, Jessica Xin, Novitski, Sif Ingibergsdóttir, Jørgensen, Isabella Friis, Siggaard, T., Vulpius, S. A., Westergaard, David, Johansen, Julia Sidenius, Chen, I. M., Jensen, Lars Juhl & Brunak, Søren, 2023, In: eLife. 12, 15 p., e84919.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Optimizing drug selection from a prescription trajectory of one patient

    Aguayo-Orozco, A., Haue, Amalie Dahl, Jørgensen, Isabella Friis, Westergaard, David, Moseley, P. L., Mortensen, Laust Hvas & Brunak, Søren, 2021, In: npj Digital Medicine. 4, 1, 150.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Novel variation and de novo mutation rates in population-wide de novo assembled Danish trios

    Besenbacher, S., Liu, S., Gonzalez-Izarzugaza, J. M., Grove, J., Belling, K. G., Bork-Jensen, J., Huang, S., Als, T. D., Li, S., Yadav, R., Rubio García, A., Lescai, F., Demontis, D., Rao, J., Ye, W., Mailund, T., Møllegaard Friborg, R., Pedersen, C. N. S., Xu, R., Sun, J. & 27 others, Liu, H., Wang, O., Cheng, X., Flores, D., Rydza, E. K., Rapacki, K., Sørensen, J. D., Chmura, P. J., Westergaard, David, Dworzynski, P., Sørensen, Thorkild I.A., Lund, O., Hansen, Torben, Xu, X., Li, N., Bolund, L., Pedersen, Oluf Borbye, Eiberg, Hans Rudolf Lytchoff, Krogh, Anders, Børglum, A. D., Brunak, Søren, Kristiansen, Karsten, Schierup, M. H., Wang, J., Gupta, R., Villesen, P. & Rasmussen, Simon, 2015, In: Nature Communications. 6, 9 p., 5969.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Linking progression patterns in ischaemic heart disease to comorbidities and genetics by integrated analysis of electronic health records and population-wide registries

    Haue, Amalie Dahl, Holm, Peter Christoffer, Siggaard, T., Jørgensen, Isabella Friis, Simone, C., Eriksson, R., Orozco, A. A., Weeke, P. E., Christensen, A. H., Westergaard, David, Banasik, Karina, Køber, Lars Valeur, Ullum, H., Bundgård, Henning & Brunak, Søren, 2020, In: European Heart Journal. 41, p. 3496 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research

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ID: 130783904