Michael Lund Nielsen

Michael Lund Nielsen

professor, group leader


  1. 2000
  2. Intramolecular hydrogen atom transfer in hydrogen-deficient polypeptide radical cations

    Nielsen, Michael Lund, Budnik, B. A., Haselmann, K. F., Olsen, Jesper Velgaard & Zubarev, R. A., 2000, In : Chemical Physics Letters. 330, 5-6, p. 558-562 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Tandem ionization mass spectrometry of biomolecules

    Zubarev, R. A., Nielsen, Michael Lund & Budnik, B. A., 2000, In : European Journal of Mass Spectrometry. 6, 3, p. 235-240 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. 2001
  5. Advantages of external accumulation for electron capture dissociation in Fourier transform mass spectrometry

    Haselmann, K. F., Budnik, B. A., Olsen, Jesper Velgaard, Nielsen, Michael Lund, Reis, C. A., Clausen, H., Johnsen, A. H. & Zubarev, R. A., 2001, In : Analytical Chemistry. 73, 13, p. 2998-3005 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Comparison of electron capture dissociation and collisionally activated dissociation of polycations of peptide nucleic acids

    Olsen, Jesper Velgaard, Haselmann, K. F., Nielsen, Michael Lund, Budnik, B. A., Nielsen, P. E. & Zubarev, R. A., 2001, In : Rapid Communications in Mass Spectrometry. 15, 12, p. 969-74 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. 2002
  8. Can relative cleavage frequencies in peptides provide additional sequence information?

    Budnik, B. A., Nielsen, Michael Lund, Olsen, Jesper Velgaard, Haselmann, K. F., Horth, P., Haehnel, W. & Zubarev, R. A., 2002, In : International Journal of Mass Spectrometry. 219, 1, p. 283-294 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Electronic excitation gives informative fragmentation of polypeptide cations and anions

    Haselmann, K. F., Budnik, B. A., Kjeldsen, F., Nielsen, Michael Lund, Olsen, Jesper Velgaard & Zubarev, R. A., 2002, In : European Journal of Mass Spectrometry. 8, 2, p. 117-121 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Peptide end sequencing by orthogonal MALDI tandem mass spectrometry

    Nielsen, Michael Lund, Bennett, K. L., Larsen, B., Moniatte, M. & Mann, M., 2002, In : Journal of Proteome Research. 1, 1, p. 63-71 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. 2003
  12. Experiences and perspectives of MALDI MS and MS/MS in proteomic research

    Rappsilber, J., Moniatte, M., Nielsen, Michael Lund, Podtelejnikov, A. V. & Mann, M., 2003, In : International Journal of Mass Spectrometry. 226, 1, p. 223-237 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Tandem MALDI/El ionization for tandem Fourier transform ion cyclotron resonance mass spectrometry of polypeptides

    Nielsen, Michael Lund, Budnik, B. A., Haselmann, K. F. & Zubarev, R. A., 2003, In : International Journal of Mass Spectrometry. 226, 1, p. 181-187 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. 2004
  15. Physicochemical properties determining the detection probability of tryptic peptides in Fourier transform mass spectrometry. A correlation study

    Nielsen, Michael Lund, Savitski, M. M., Kjeldsen, F. & Zubarev, R. A., 2004, In : Analytical Chemistry. 76, 19, p. 5872-5877 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Shifted-basis technique improves accuracy of peak position determination in Fourier transform mass spectrometry

    Savitski, M. M., Ivonin, I. A., Nielsen, Michael Lund, Zubarev, R. A., Tsybin, Y. O. & Hakansson, P., 2004, In : Journal of The American Society for Mass Spectrometry. 15, 4, p. 457-461 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. HysTag--a novel proteomic quantification tool applied to differential display analysis of membrane proteins from distinct areas of mouse brain

    Olsen, Jesper Velgaard, Andersen, J. R., Nielsen, P. A., Nielsen, Michael Lund, Figeys, D., Mann, Matthias & Wisniewski, J. R., Jan 2004, In : Molecular and Cellular Proteomics. 3, 1, p. 82-92 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. 2005
  19. Improving protein identification using complementary fragmentation techniques in Fourier transform mass spectrometry

    Nielsen, Michael Lund, Savitski, M. M. & Zubarev, R. A., 2005, In : Molecular and Cellular Proteomics. 4, 6, p. 835-845 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. New data base-independent, sequence tag-based scoring of peptide MS/MS data validates Mowse scores, recovers below threshold data, singles out modified peptides, and assesses the quality of MS/MS techniques

    Savitski, M. M., Nielsen, Michael Lund & Zubarev, R. A., 2005, In : Molecular and Cellular Proteomics. 4, 8, p. 1180-1188 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Proteomics-grade de novo sequencing approach

    Savitski, M. M., Nielsen, Michael Lund, Kjeldsen, F. & Zubarev, R. A., 2005, In : Journal of Proteome Research. 4, 6, p. 2348-2354 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Toward error-free proteomics

    Zubarev, R., Nielsen, Michael Lund, Savitski, M. & Kocher, T., 2005, In : Molecular and Cellular Proteomics. 4, 8, p. S16-S16

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. 2006
  24. Complementary sequence preferences of electron-capture dissociation and vibrational excitation in fragmentation of polypeptide polycations

    Savitski, M. M., Kjeldsen, F., Nielsen, Michael Lund & Zubarev, R. A., 2006, In : Angewandte Chemie International Edition. 45, 32, p. 5301-5303 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Extent of modifications in human proteome samples and their effect on dynamic range of analysis in shotgun proteomics

    Nielsen, Michael Lund, Savitski, M. M. & Zubarev, R. A., 2006, In : Molecular and Cellular Proteomics. 5, 12, p. 2384-2391 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Liquid chromatography at critical conditions: Comprehensive approach to sequence-dependent retention time prediction

    Gorshkov, A. V., Tarasova, I. A., Evreinov, V. V., Savitski, M. M., Nielsen, Michael Lund, Zubarev, R. A. & Gorshkov, M. V., 2006, In : Analytical Chemistry. 78, 22, p. 7770-7777 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. ModifiComb, a new proteomic tool for mapping substoichiometric post-translational modifications, finding novel types of modifications, and fingerprinting complex protein mixtures

    Savitski, M. M., Nielsen, Michael Lund & Zubarev, R. A., 2006, In : Molecular and Cellular Proteomics. 5, 5, p. 935-948 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. PhosTShunter: A fast and reliable tool to detect phosphorylated peptides in liquid chromatography Fourier transform tandem mass spectrometry data sets

    Kocher, T., Savitski, M. M., Nielsen, Michael Lund & Zubarev, R. A., 2006, In : Journal of Proteome Research. 5, 3, p. 659-668 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. 2007
  30. Backbone carbonyl group basicities are related to gas-phase fragmentation of peptides and protein folding

    Savitski, M. M., Kjeldsen, F., Nielsen, Michael Lund, Garbuzynskiy, S. O., Galzitskaya, O. V., Surin, A. K. & Zubarev, R. A., 2007, In : Angewandte Chemie International Edition. 46, 9, p. 1481-1484 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. De novo peptide sequencing and identification with precision mass spectrometry

    Frank, A. M., Savitski, M. M., Nielsen, Michael Lund, Zubarev, R. A. & Pevzner, P. A., 2007, In : Journal of Proteome Research. 6, 1, p. 114-123 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Electrospray ionization tandem mass spectrometry sequencing of novel skin peptides from Ranid frogs containing disulfide bridges

    Samgina, T., Arternenko, K., Gorshkov, V., Lebedev, A., Nielsen, Michael Lund, Savitski, M. & Zubarev, R., 2007, In : European Journal of Mass Spectrometry. 13, 2, p. 155-163 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Hydrogen rearrangement to and from radical z fragments in electron capture dissociation of peptides

    Savitski, M. M., Kjeldsen, F., Nielsen, Michael Lund & Zubarev, R. A., 2007, In : Journal of The American Society for Mass Spectrometry. 18, 1, p. 113-120 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. On studying protein phosphorylation patterns using bottom-up LC-MS/MS: the case of human alpha-casein

    Kjeldsen, F., Savitski, M. M., Nielsen, Michael Lund, Shi, L. & Zubarev, R. A., 2007, In : Analyst. 132, 8, p. 768-776 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Relative specificities of water and ammonia losses from backbone fragments in collision-activated dissociation

    Savitski, M. M., Kjeldsen, F., Nielsen, Michael Lund & Zubarev, R. A., 2007, In : Journal of Proteome Research. 6, 7, p. 2669-2673 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Side-chain losses in electron capture dissociation to improve peptide identification

    Savitski, M. M., Nielsen, Michael Lund & Zubarev, R. A., 2007, In : Analytical Chemistry. 79, 6, p. 2296-2302 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. SwedCAD, a database of annotated high-mass accuracy MS/MS spectra of tryptic peptides

    Falth, M., Savitski, M. M., Nielsen, Michael Lund, Kjeldsen, F., Andren, P. E. & Zubarev, R. A., 2007, In : Journal of Proteome Research. 6, 10, p. 4063-4067 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. The RBCC gene RFP2 (leu5) encodes a novel transmembrane E3 ubiquitin ligase involved in ERAD

    Lerner, M., Corcoran, M., Cepeda, D., Nielsen, Michael Lund, Zubarev, R., Ponten, F., Uhlen, M., Hober, S., Grander, D. & Sangfelt, O., 2007, In : Molecular Biology of the Cell. 18, 5, p. 1670-1682 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. 2008
  40. Analytical Utility of Small Neutral Losses from Reduced Species in Electron Capture Dissociation Studied Using SwedECD Database

    Falth, M., Savitski, M. M., Nielsen, Michael Lund, Kjeldsen, F., Andren, P. E. & Zubarev, R. A., 2008, In : Analytical Chemistry. 80, 21, p. 8089-8094 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Comprehensive mass-spectrometry-based proteome quantification of haploid versus diploid yeast

    de Godoy, L. M. F., Olsen, J. V., Cox, J., Nielsen, Michael Lund, Hubner, N. C., Fröhlich, F., Walther, T. C. & Mann, M., 2008, In : Nature. 455, 7217, p. 1251-4 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Identification of dominant signaling pathways from proteomics expression data

    Zubarev, R. A., Nielsen, Michael Lund, Fung, E. M., Savitski, M. M., Kel-Margoulis, O., Wingender, E. & Kel, A., 2008, In : Journal of Proteomics. 71, 1, p. 89-96 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Immunoaffinity enrichments followed by mass spectrometric detection for studying global protein tyrosine phosphorylation

    Lind, S. B., Molin, M., Savitski, M. M., Emilsson, L., Astrom, J., Hedberg, L., Adams, C., Nielsen, Michael Lund, Engstrom, A., Elfineh, L., Andersson, E., Zubarev, R. A. & Pettersson, U., 2008, In : Journal of Proteome Research. 7, 7, p. 2897-2910 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Iodoacetamide-induced artifact mimics ubiquitination in mass spectrometry

    Nielsen, Michael Lund, Vermeulen, M., Bonaldi, T., Cox, J., Moroder, L. & Mann, M., 2008, In : Nature Methods. 5, 6, p. 459-460 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. 2009
  46. A dual pressure linear ion trap orbitrap instrument with very high sequencing speed

    Olsen, Jesper Velgaard, Schwartz, J. C., Griep-Raming, J., Nielsen, Michael Lund, Damoc, E., Denisov, E., Lange, O., Remes, P., Taylor, D., Splendore, M., Wouters, E. R., Senko, M., Makarov, A., Mann, Matthias & Horning, S., 2009, In : Molecular and Cellular Proteomics. 8, 12, p. 2759-69 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Analysis of in vivo histone methylation kinetics by Heavy Methyl SILAC

    Bonaldi, T., Vitale, E., Nielsen, Michael Lund, Cox, J. & Mann, M., 2009, In : Amino Acids. 37, p. 66 1 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Jmjd6 Catalyses Lysyl-Hydroxylation of U2AF65, a Protein Associated with RNA Splicing

    Webby, C. J., Wolf, A., Gromak, N., Dreger, M., Kramer, H., Kessler, B., Nielsen, Michael Lund, Schmitz, C., Butler, D. S., Yates, J. R., Delahunty, C. M., Hahn, P., Lengeling, A., Mann, M., Proudfoot, N. J., Schofield, C. J. & Boettger, A., 2009, In : Science. 325, 5936, p. 90-93 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Lysine acetylation targets protein complexes and co-regulates major cellular functions

    Choudhary, Chuna Ram, Kumar, C., Gnad, F., Nielsen, Michael Lund, Rehman, M., Walther, T. C., Olsen, Jesper Velgaard & Mann, Matthias, 2009, In : Science. 325, 5942, p. 834-40 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. 2011
  51. ATP Enhances Neuronal Differentiation of PC12 Cells by Activating PKC alpha Interactions with Cytoskeletal Proteins

    Marin-Vicente, C., Guerrero-Valero, M., Nielsen, Michael Lund, Savitski, M. M., Gomez-Fernandez, J. C., Zubarev, R. A. & Corbalan-Garcia, S., 2011, In : Journal of Proteome Research. 10, 2, p. 529-540 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    The SOCS2 Ubiquitin Ligase Complex Regulates Growth Hormone Receptor Levels

    Vesterlund, M., Zadjali, F., Persson, T., Nielsen, Michael Lund, Kessler, B. M., Norstedt, G. & Flores Morales, A., 1 Jan 2011, In : P L o S One. 6, 9, p. e25358 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level

    Danielsen, J. M. R., Sylvestersen, K. B., Bekker-Jensen, Simon Holst, Szklarczyk, D., Poulsen, J. W., Horn, H., Jensen, Lars Juhl, Mailand, Niels & Nielsen, Michael Lund, 1 Mar 2011, In : Molecular and Cellular Proteomics. 10, 3, p. M110.003590

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    A Proteome-wide, Quantitative Survey of In Vivo Ubiquitylation Sites Reveals Widespread Regulatory Roles

    Wagner, S. A., Beli, P., Weinert, B. T., Nielsen, Michael Lund, Cox, J., Mann, Matthias & Choudhary, Chuna Ram, 1 Oct 2011, In : Molecular and Cellular Proteomics. 10, 10, p. M111.013284

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. 2012
  56. Published

    Comprehensive profiling of proteome changes upon sequential deletion of deubiquitylating enzymes

    Poulsen, J. W., Madsen, C. T., Young, C., Kelstrup, C. D., Grell, H. C., Henriksen, P., Jensen, Lars Juhl & Nielsen, Michael Lund, 2012, In : Journal of Proteomics. 75, 13, p. 3886-97 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    Optimized Fast and Sensitive Acquisition Methods for Shotgun Proteomics on a Quadrupole Orbitrap Mass Spectrometer

    Kelstrup, C. D., Young, C., Lavallee, R., Nielsen, Michael Lund & Olsen, Jesper Velgaard, 2012, In : Journal of Proteome Research. p. 3487-3497 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    Pdx1 is post-translationally modified in vivo and serine 61 is the principal site of phosphorylation

    Frogne, T., Sylvestersen, K. B., Kubicek, S., Nielsen, Michael Lund & Hecksher-Sørensen, J., 2012, In : P L o S One. 7, 4, p. e35233

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    Proteomic analyses reveal divergent ubiquitylation site patterns in murinetissues

    Wagner, S. A., Beli, P., Weinert, B. T., Schölz, C. F., Kelstrup, C. D., Young, C., Nielsen, Michael Lund, Olsen, Jesper Velgaard, Brakebusch, Cord Herbert & Choudhary, Chuna Ram, 2012, In : Molecular & Cellular Proteomics.

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    Self-hydroxylation of the splicing factor lysyl hydroxylase, JMJD6

    Mantri, M., Webby, C. J., Loik, N. D., Hamed, R. B., McDonough, M. A., McCullagh, J. S. O., Schofield, C. J., Wolf, A., Nielsen, Michael Lund & Böttger, A., 1 Jan 2012, In : MedChemComm. 3, 1, p. 80-85 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. Published

    The molecular basis of ATM-dependent dimerization of the Mdc1 DNA damage checkpoint mediator.

    Jungmichel, S., Clapperton, J. A., Janette, L., Hari, F. J., Spycher, C., Pavic, L., Li, J., Haire, L. F., Bonalli, M., Larsen, D. H., Lukas, C., Lukas, J., MacMillan, D., Nielsen, Michael Lund, Stucki, M. & Smerdon, S. J., 10 Jan 2012, In : Nucleic Acids Research. 40, 9, p. 4913-4928 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. Published

    Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass

    Povlsen, L. K., Beli, P., Wagner, S. A., Poulsen, S. L., Sylvestersen, K. B., Poulsen, J. W., Nielsen, Michael Lund, Bekker-Jensen, Simon Holst, Mailand, Niels & Choudhary, Chuna Ram, Oct 2012, In : Nature Cell Biology. 14, 10, p. 1089-98 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. 2013
  64. Published

    Effectiveness of a coordinated and tailored return-to-work intervention for sickness absence beneficiaries with mental health problems

    Martin, M., Nielsen, Michael Lund, Madsen, I., Petersen, S., Lange, Theis & Rugulies, R., 2013, In : Journal of Occupational Rehabilitation. 23, 4, p. 621-30 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. Published

    Novel serological neo-epitope markers of extracellular matrix proteins for the detection of portal hypertension

    Leeming, D. J., Karsdal, M. A., Byrjalsen, I., Bendtsen, Flemming, Trebicka, J., Nielsen, Michael Lund, Christiansen, C., Møller, Søren & Krag, A., 2013, In : Alimentary Pharmacology and Therapeutics. 38, 9, p. 1086-1096 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  66. Published

    RNA-DNA sequence differences spell genetic code ambiguities

    Bentin, Thomas & Nielsen, Michael Lund, 2013, In : Artificial DNA. 2, 3, p. 69-70 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  67. Published

    Using guanidine-hydrochloride for fast and efficient protein digestion and single-step affinity-purification mass spectrometry

    Poulsen, J. W., Madsen, C. T., Young, C., Poulsen, F. M. & Nielsen, Michael Lund, 2013, In : Journal of Proteome Research. 12, 2, p. 1020-30 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. Published

    Advances in characterizing ubiquitylation sites by mass spectrometry

    Sylvestersen, K. B., Young, C. & Nielsen, Michael Lund, 5 Jan 2013, In : Current Opinion in Chemical Biology. 17, 1, p. 49-58 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. Published

    CDK-mediated activation of the SCF(FBXO) (28) ubiquitin ligase promotes MYC-driven transcription and tumourigenesis and predicts poor survival in breast cancer

    Cepeda, D., Ng, H., Sharifi, H. R., Mahmoudi, S., Cerrato, V. S., Fredlund, E., Magnusson, K., Nilsson, H., Malyukova, A., Rantala, J., Klevebring, D., Viñals, F., Bhaskaran, N., Zakaria, S. M., Rahmanto, A. S., Grotegut, S., Nielsen, Michael Lund, Szigyarto, C. A., Sun, D., Lerner, M., Navani, S., Widschwendter, M., Uhlén, M., Jirström, K., Pontén, F., Wohlschlegel, J., Grandér, D., Spruck, C., Larsson, L. & Sangfelt, O., 3 Jul 2013, In : E M B O Molecular Medicine (Online). 5, 7, p. 1067-1086 20 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  70. Published

    A new cellular stress response that triggers centriolar satellite reorganization and ciliogenesis

    Villumsen, B. H., Danielsen, J. R., Povlsen, L., Sylvestersen, K. B., Merdes, A., Beli, P., Yang, Y., Choudhary, Chuna Ram, Nielsen, Michael Lund, Mailand, Niels & Bekker-Jensen, Simon Holst, 11 Oct 2013, In : E M B O Journal. 32, 23, p. 3029-3040

    Research output: Contribution to journalJournal articleResearchpeer-review

  71. Published

    Proteome-wide Identification of Poly(ADP-Ribosyl)ation Targets in Different Genotoxic Stress Responses

    Jungmichel, S., Rosenthal, F., Altmeyer, M., Lukas, Jiri, Hottiger, M. O. & Nielsen, Michael Lund, 24 Oct 2013, In : Molecular Cell. 52, 2, p. 272-285 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  72. 2014
  73. Published

    Tousled-like kinases phosphorylate Asf1 to promote histone supply during DNA replication

    Kamalyukova, I. M., Young, C., Strømme, C. B., Ménard, Patrice, Jasencakova, Zuzana, Mejlvang, J., Ask, K., Ploug, Michael, Nielsen, Michael Lund, Jensen, O. N. & Groth, Anja, 2014, In : Nature Communications. 5, p. 3394

    Research output: Contribution to journalJournal articleResearchpeer-review

  74. Published

    Glutamine methylation in histone H2A is an RNA-polymerase-I-dedicated modification

    Tessarz, P., Santos-Rosa, H., Robson, S. C., Sylvestersen, K. B., Nelson, C. J., Nielsen, Michael Lund & Kouzarides, T., 23 Jan 2014, In : Nature. 505, p. 564-568

    Research output: Contribution to journalJournal articleResearchpeer-review

  75. Published

    Protein Interaction Screening for the Ankyrin Repeats and Suppressor of Cytokine Signaling (SOCS) Box (ASB) Family Identify Asb11 as a Novel Endoplasmic Reticulum Resident Ubiquitin Ligase

    Andresen, C. A., Smedegaard, S., Sylvestersen, K. B., Svensson, C., Iglesias Gato, Diego, Cazzamali, G., Nielsen, T. K., Nielsen, Michael Lund & Flores Morales, A., 24 Jan 2014, In : The Journal of Biological Chemistry. 289, 4, p. 2043-2054 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  76. Published

    Specificity and commonality of the phosphoinositide-binding proteome analyzed by quantitative mass spectrometry

    Jungmichel, S., Sylvestersen, K. B., Choudhary, Chuna Ram, Nguyen, S., Mann, Matthias & Nielsen, Michael Lund, 13 Feb 2014, In : Cell Reports. 6, 3, p. 578-91 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  77. Published

    Proteomic analysis of arginine methylation sites in human cells reveals dynamic regulation during transcriptional arrest

    Sylvestersen, K. B., Horn, H., Jungmichel, S., Jensen, Lars Juhl & Nielsen, Michael Lund, 21 Feb 2014, In : Molecular & Cellular Proteomics. 13, p. 2072-2088 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  78. Published

    Citrullination regulates pluripotency and histone H1 binding to chromatin

    Christophorou, M. A., Castelo-Branco, G., Halley-Stott, R. P., Oliveira, C. S., Loos, R., Radzisheuskaya, A., Mowen, K. A., Bertone, P., Silva, J. C. R., Zernicka-Goetz, M., Nielsen, Michael Lund, Gurdon, J. B. & Kouzarides, T., 6 Mar 2014, In : Nature. 507, p. 104-108

    Research output: Contribution to journalJournal articleResearchpeer-review

  79. Published

    Analytical utility of mass spectral binning in proteomic experiments by SPectral Immonium Ion Detection (SPIID)

    Kelstrup, C. D., Freese, C., Heck, A. J. R., Olsen, Jesper Velgaard & Nielsen, Michael Lund, 3 Jun 2014, In : Molecular & Cellular Proteomics. 13, 8, p. 1914-1924 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  80. Published

    The NBS1-Treacle complex controls ribosomal RNA transcription in response to DNA damage

    Larsen, D. H., Hari, F., Clapperton, J. A., Gwerder, M., Gutsche, K., Altmeyer, M., Jungmichel, S., Toledo Lazaro, Luis Ignacio, Fink, D., Rask, M., Grøfte, M., Lukas, Claudia, Nielsen, Michael Lund, Smerdon, S. J., Lukas, Jiri & Stucki, M., Aug 2014, In : Nature Cell Biology. 16, 8, p. 792-803 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  81. 2015
  82. Published

    A two-step protein quality control pathway for a misfolded DJ-1 variant in fission yeast

    Mathiassen, S. G., Larsen, I. B., Poulsen, E. G., Madsen, C. T., Papaleo, Elena, Lindorff-Larsen, Kresten, Kragelund, Birthe Brandt, Nielsen, Michael Lund, Kriegenburg, F. & Hartmann-Petersen, Rasmus, 2015, In : The Journal of Biological Chemistry. 290, 34, p. 21141-21153 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  83. Published

    Biotin starvation causes mitochondrial protein hyperacetylation and partial rescue by the SIRT3-like deacetylase Hst4p

    Madsen, C. T., Sylvestersen, K. B., Young, C., Buch-Larsen, Sara Charlotte, Poulsen, J. W., Andersen, M. A., Palmqvist, E. A., Hey-Mogensen, M., Jensen, P. B., Treebak, Jonas Thue, Lisby, Michael & Nielsen, Michael Lund, 2015, In : Nature Communications. 6, 12 p., 7726.

    Research output: Contribution to journalJournal articleResearchpeer-review

  84. Published

    Direct neuronal glucose uptake Heralds activity-dependent increases in cerebral metabolism

    Lundgaard, I., Li, B., Xie, L., Kang, H., Sanggaard, S., Haswell, J. D. R., Sun, W., Goldman, S., Blekot, S., Nielsen, Michael Lund, Takano, T., Deane, R. & Nedergaard, Maiken, 2015, In : Nature Communications. 6, 12 p., 6807.

    Research output: Contribution to journalJournal articleResearchpeer-review

  85. Published

    Liquid demixing of intrinsically disordered proteins is seeded by poly(ADP-ribose)

    Altmeyer, M., Neelsen, K. J., Teloni, F., Pozdnyakova, I., Pellegrino, S., Grøfte, M., Rask, M. D., Streicher, W., Jungmichel, S., Nielsen, Michael Lund & Lukas, Jiri, 19 Aug 2015, In : Nature Communications. 6, p. 1-12 8088.

    Research output: Contribution to journalJournal articleResearchpeer-review

  86. Published

    Large-Scale Identification of the Arginine Methylome by Mass Spectrometry

    Sylvestersen, K. B. & Nielsen, Michael Lund, 2 Nov 2015, Current Protocols in Protein Science. Vol. 82. 17 p. (Current Protocols in Protein Science).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  87. 2016
  88. Published

    Proteome-wide analysis of arginine monomethylation reveals widespread occurrence in human cells

    Buch-Larsen, Sara Charlotte, Sylvestersen, K. B., Mund, Andreas, Lyon, D., Mullari, Meeli, Vistrup-Parry, Maria, Daniel, J. A., Jensen, Lars Juhl & Nielsen, Michael Lund, 30 Aug 2016, In : Science signaling. 9, 443, 14 p., rs9.

    Research output: Contribution to journalJournal articleResearchpeer-review

  89. Published

    Proteome-wide identification of the endogenous ADP-ribosylome of mammalian cells and tissue

    Martello, R., Leutert, M., Jungmichel, S., Bilan, V., Buch-Larsen, Sara Charlotte, Young, C., Hottiger, M. O. & Nielsen, Michael Lund, 1 Oct 2016, In : Nature Communications. 7, 13 p., 12917.

    Research output: Contribution to journalJournal articleResearchpeer-review

  90. 2017
  91. Published

    An Optimized Shotgun Strategy for the Rapid Generation of Comprehensive Human Proteomes

    Bekker-Jensen, D. B., Kelstrup, C. D., Batth, Tanveer Singh, Buch-Larsen, Sara Charlotte, Haldrup, C., Bramsen, J. B., Sørensen, K. D., Høyer, S., Ørntoft, T. F., Andersen, C. L., Nielsen, Michael Lund & Olsen, Jesper Velgaard, 2017, In : Cell Systems. 4, 6, p. 587-599, e1-e4 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  92. Published

    Citrullination modulates oligodendrocyte differentiation

    Falcao, A., Meijer, M., Rinwa, P., Cummings, T., Varas, M., Liang, J., Casaccia, P., Christophorou, M., Nielsen, Michael Lund, Ernfors, P. & Castelo-Branco, G., 2017, In : Glia. 65, S1, p. E389 1 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  93. Published

    Proteome-Wide Identification of In Vivo ADP-Ribose Acceptor Sites by Liquid Chromatography-Tandem Mass Spectrometry

    Buch-Larsen, Sara Charlotte, Leutert, M., Bilan, V., Martello, R., Jungmichel, S., Young, C., Hottiger, M. O. & Nielsen, Michael Lund, 2017, Poly(ADP-Ribose) Polymerase. Tulin, A. V. (ed.). Humana Press, Vol. 1608. p. 149-162 14 p. (Methods in molecular biology (Clifton, N.J.)).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  94. Published

    Specifying RNA-Binding Regions in Proteins by Peptide Cross-Linking and Affinity Purification

    Mullari, Meeli, Lyon, D., Jensen, Lars Juhl & Nielsen, Michael Lund, 2017, In : Journal of Proteome Research. 16, 8, p. 2762-2772 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  95. Published

    Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation

    Hendriks, Ivo Alexander, Lyon, D., Young, C., Jensen, Lars Juhl, Vertegaal, A. C. O. & Nielsen, Michael Lund, Mar 2017, In : Nature Structural and Molecular Biology. 24, 3, p. 325-336 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  96. Published

    Improved Reversed Phase Chromatography of Hydrophilic Peptides from Spatial and Temporal Changes in Column Temperature

    Young, C., Podtelejnikov, A. V. & Nielsen, Michael Lund, 2 Jun 2017, In : Journal of Proteome Research. 16, 6, p. 2307-2317 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  97. Published

    Bub1 positions Mad1 close to KNL1 MELT repeats to promote checkpoint signalling

    Zhang, G., Kruse, Thomas, López-Méndez, B., Sylvestersen, K. B., Garvanska, Dimitriya Hristoforova, Schopper, S., Nielsen, Michael Lund & Nilsson, Jakob, 12 Jun 2017, In : Nature Communications. 8, 12 p., 15822.

    Research output: Contribution to journalJournal articleResearchpeer-review

  98. 2018
  99. Published

    Arginine Methylation by PRMT2 Controls the Functions of the Actin Nucleator Cobl

    Hou, W., Nemitz, S., Schopper, S., Nielsen, Michael Lund, Kessels, M. M. & Qualmann, B., 2018, In : Developmental Cell. 45, 2, p. 262-275.E8

    Research output: Contribution to journalJournal articleResearchpeer-review

  100. Published

    Integrative Characterization of the R6/2 Mouse Model of Huntington's Disease Reveals Dysfunctional Astrocyte Metabolism

    Skotte, Niels Henning, Andersen, Jens Velde, Santos, A., Aldana Garcia, Blanca Irene, Willert, C. W., Nørremølle, Anne, Waagepetersen, Helle S. & Nielsen, Michael Lund, 2018, In : Cell Reports. 23, 7, p. 2211-2224 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  101. Published

    Site-specific characterization of endogenous SUMOylation across species and organs

    Hendriks, Ivo Alexander, Lyon, D., Su, D., Skotte, Niels Henning, Daniel, J. A., Jensen, Lars Juhl & Nielsen, Michael Lund, 2018, In : Nature Communications. 9, p. 1-17 2456.

    Research output: Contribution to journalJournal articleResearchpeer-review

  102. Published

    Systems-wide Analysis of Serine ADP-Ribosylation Reveals Widespread Occurrence and Site-Specific Overlap with Phosphorylation

    Buch-Larsen, Sara Charlotte, Hendriks, Ivo Alexander, Lyon, D., Jensen, Lars Juhl & Nielsen, Michael Lund, 2018, In : Cell Reports. 24, 9, p. 2493-2505

    Research output: Contribution to journalJournal articleResearchpeer-review

  103. 2019
  104. Published

    An advanced strategy for comprehensive profiling of ADP-ribosylation sites using mass spectrometry-based proteomics

    Hendriks, Ivo Alexander, Buch-Larsen, Sara Charlotte & Nielsen, Michael Lund, 2019, In : Molecular and Cellular Proteomics. 18, 5, p. 1010-1026

    Research output: Contribution to journalJournal articleResearchpeer-review

  105. Published

    Citrullination of HP1γ chromodomain affects association with chromatin

    Wiese, M., Bannister, A. J., Basu, S., Boucher, W., Wohlfahrt, K., Christophorou, M. A., Nielsen, Michael Lund, Klenerman, D., Laue, E. D. & Kouzarides, T., 2019, In : Epigenetics & Chromatin. 12, 17 p., 21.

    Research output: Contribution to journalJournal articleResearchpeer-review

  106. Published

    Interaction of Sox2 with RNA binding proteins in mouse embryonic stem cells

    Samudyata, Amaral, P. P., Engström, P. G., Robson, S. C., Nielsen, Michael Lund, Kouzarides, T. & Castelo-Branco, G., 2019, In : Experimental Cell Research. 381, 1, p. 129-138 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  107. Published

    PAD2-Mediated Citrullination Contributes to Efficient Oligodendrocyte Differentiation and Myelination

    Falcão, A. M., Meijer, M., Scaglione, A., Rinwa, P., Agirre, E., Liang, J., Buch-Larsen, Sara Charlotte, Heskol, A., Frawley, R., Klingener, M., Varas-Godoy, M., Raposo, A. A. S. F., Ernfors, P., Castro, D. S., Nielsen, Michael Lund, Casaccia, P. & Castelo-Branco, G., 2019, In : Cell Reports. 27, 4, p. 1090-1102.e10

    Research output: Contribution to journalJournal articleResearchpeer-review

  108. Published

    Regulation of GLI1 by cis DNA elements and epigenetic marks

    Taylor, R., Long, J., Yoon, J. W., Childs, R., Sylvestersen, K. B., Nielsen, Michael Lund, Leong, K., Iannaccone, S., Walterhouse, D. O., Robbins, D. J. & Iannaccone, P., 2019, In : DNA Repair. 79, p. 10-21 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  109. Published

    SUMOylation promotes protective responses to DNA-protein crosslinks

    Borgermann, N., Ackermann, Leena, Schwertman, P., Hendriks, Ivo Alexander, Thijssen, K., Liu, Julio, Lans, H., Nielsen, Michael Lund & Mailand, Niels, 2019, In : E M B O Journal. 38, 17 p., e101496.

    Research output: Contribution to journalJournal articleResearchpeer-review

  110. 2020
  111. Published

    Multi-site SUMOylation restrains DNA polymerase η interactions with DNA damage sites

    Guerillon, Claire Aline, Smedegaard, S., Hendriks, Ivo Alexander, Nielsen, Michael Lund & Mailand, Niels, 2020, In : Journal of Biological Chemistry. 295, p. 8350-8362

    Research output: Contribution to journalJournal articleResearchpeer-review

  112. Published

    Treacle controls the nucleolar response to rDNA breaks via TOPBP1 recruitment and ATR activation

    Mooser, C., Symeonidou, I., Leimbacher, P., Ribeiro, A., Shorrocks, A. K., Jungmichel, S., Buch-Larsen, Sara Charlotte, Knechtle, K., Jasrotia, A., Zurbriggen, D., Jeanrenaud, A., Leikauf, C., Fink, D., Nielsen, Michael Lund, Blackford, A. N. & Stucki, M., 8 Jan 2020, In : Nature Communications. 11, 1, p. 123

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 13143239