Michael Lund Nielsen
Professor
Nielsen Group
Blegdamsvej 3B
2200 København N
- 2007
On studying protein phosphorylation patterns using bottom-up LC-MS/MS: the case of human alpha-casein
Kjeldsen, F., Savitski, M. M., Nielsen, Michael Lund, Shi, L. & Zubarev, R. A., 2007, In: Analyst. 132, 8, p. 768-776 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Relative specificities of water and ammonia losses from backbone fragments in collision-activated dissociation
Savitski, M. M., Kjeldsen, F., Nielsen, Michael Lund & Zubarev, R. A., 2007, In: Journal of Proteome Research. 6, 7, p. 2669-2673 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
Side-chain losses in electron capture dissociation to improve peptide identification
Savitski, M. M., Nielsen, Michael Lund & Zubarev, R. A., 2007, In: Analytical Chemistry. 79, 6, p. 2296-2302 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
SwedCAD, a database of annotated high-mass accuracy MS/MS spectra of tryptic peptides
Falth, M., Savitski, M. M., Nielsen, Michael Lund, Kjeldsen, F., Andren, P. E. & Zubarev, R. A., 2007, In: Journal of Proteome Research. 6, 10, p. 4063-4067 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
The RBCC gene RFP2 (leu5) encodes a novel transmembrane E3 ubiquitin ligase involved in ERAD
Lerner, M., Corcoran, M., Cepeda, D., Nielsen, Michael Lund, Zubarev, R., Ponten, F., Uhlen, M., Hober, S., Grander, D. & Sangfelt, O., 2007, In: Molecular Biology of the Cell. 18, 5, p. 1670-1682 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2008
Analytical Utility of Small Neutral Losses from Reduced Species in Electron Capture Dissociation Studied Using SwedECD Database
Falth, M., Savitski, M. M., Nielsen, Michael Lund, Kjeldsen, F., Andren, P. E. & Zubarev, R. A., 2008, In: Analytical Chemistry. 80, 21, p. 8089-8094 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
Comprehensive mass-spectrometry-based proteome quantification of haploid versus diploid yeast
de Godoy, L. M. F., Olsen, J. V., Cox, J., Nielsen, Michael Lund, Hubner, N. C., Fröhlich, F., Walther, T. C. & Mann, M., 2008, In: Nature. 455, 7217, p. 1251-4 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
Identification of dominant signaling pathways from proteomics expression data
Zubarev, R. A., Nielsen, Michael Lund, Fung, E. M., Savitski, M. M., Kel-Margoulis, O., Wingender, E. & Kel, A., 2008, In: Journal of Proteomics. 71, 1, p. 89-96 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
Immunoaffinity enrichments followed by mass spectrometric detection for studying global protein tyrosine phosphorylation
Lind, S. B., Molin, M., Savitski, M. M., Emilsson, L., Astrom, J., Hedberg, L., Adams, C., Nielsen, Michael Lund, Engstrom, A., Elfineh, L., Andersson, E., Zubarev, R. A. & Pettersson, U., 2008, In: Journal of Proteome Research. 7, 7, p. 2897-2910 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
Iodoacetamide-induced artifact mimics ubiquitination in mass spectrometry
Nielsen, Michael Lund, Vermeulen, M., Bonaldi, T., Cox, J., Moroder, L. & Mann, M., 2008, In: Nature Methods. 5, 6, p. 459-460 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2009
A dual pressure linear ion trap orbitrap instrument with very high sequencing speed
Olsen, Jesper Velgaard, Schwartz, J. C., Griep-Raming, J., Nielsen, Michael Lund, Damoc, E., Denisov, E., Lange, O., Remes, P., Taylor, D., Splendore, M., Wouters, E. R., Senko, M., Makarov, A., Mann, Matthias & Horning, S., 2009, In: Molecular and Cellular Proteomics. 8, 12, p. 2759-69 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Analysis of in vivo histone methylation kinetics by Heavy Methyl SILAC
Bonaldi, T., Vitale, E., Nielsen, Michael Lund, Cox, J. & Mann, M., 2009, In: Amino Acids. 37, p. 66 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
Jmjd6 Catalyses Lysyl-Hydroxylation of U2AF65, a Protein Associated with RNA Splicing
Webby, C. J., Wolf, A., Gromak, N., Dreger, M., Kramer, H., Kessler, B., Nielsen, Michael Lund, Schmitz, C., Butler, D. S., Yates, J. R., Delahunty, C. M., Hahn, P., Lengeling, A., Mann, M., Proudfoot, N. J., Schofield, C. J. & Boettger, A., 2009, In: Science. 325, 5936, p. 90-93 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lysine acetylation targets protein complexes and co-regulates major cellular functions
Choudhary, Chunaram, Kumar, C., Gnad, F., Nielsen, Michael Lund, Rehman, M., Walther, T. C., Olsen, Jesper Velgaard & Mann, Matthias, 2009, In: Science. 325, 5942, p. 834-40 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2011
ATP Enhances Neuronal Differentiation of PC12 Cells by Activating PKC alpha Interactions with Cytoskeletal Proteins
Marin-Vicente, C., Guerrero-Valero, M., Nielsen, Michael Lund, Savitski, M. M., Gomez-Fernandez, J. C., Zubarev, R. A. & Corbalan-Garcia, S., 2011, In: Journal of Proteome Research. 10, 2, p. 529-540 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The SOCS2 Ubiquitin Ligase Complex Regulates Growth Hormone Receptor Levels
Vesterlund, M., Zadjali, F., Persson, T., Nielsen, Michael Lund, Kessler, B. M., Norstedt, G. & Flores Morales, A., 1 Jan 2011, In: P L o S One. 6, 9, p. e25358 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level
Danielsen, J. M. R., Sylvestersen, K. B., Bekker-Jensen, Simon Holst, Szklarczyk, D., Poulsen, J. W., Horn, H., Jensen, Lars Juhl, Mailand, Niels & Nielsen, Michael Lund, 1 Mar 2011, In: Molecular and Cellular Proteomics. 10, 3, p. M110.003590Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Proteome-wide, Quantitative Survey of In Vivo Ubiquitylation Sites Reveals Widespread Regulatory Roles
Wagner, S. A., Beli, P., Weinert, B. T., Nielsen, Michael Lund, Cox, J., Mann, Matthias & Choudhary, Chunaram, 1 Oct 2011, In: Molecular and Cellular Proteomics. 10, 10, p. M111.013284Research output: Contribution to journal › Journal article › Research › peer-review
- 2012
- Published
Comprehensive profiling of proteome changes upon sequential deletion of deubiquitylating enzymes
Poulsen, J. W., Madsen, C. T., Young, C., Kelstrup, C. D., Grell, H. C., Henriksen, P., Jensen, Lars Juhl & Nielsen, Michael Lund, 2012, In: Journal of Proteomics. 75, 13, p. 3886-97 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Optimized Fast and Sensitive Acquisition Methods for Shotgun Proteomics on a Quadrupole Orbitrap Mass Spectrometer
Kelstrup, C. D., Young, C., Lavallee, R., Nielsen, Michael Lund & Olsen, Jesper Velgaard, 2012, In: Journal of Proteome Research. p. 3487-3497 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pdx1 is post-translationally modified in vivo and serine 61 is the principal site of phosphorylation
Frogne, T., Sylvestersen, K. B., Kubicek, S., Nielsen, Michael Lund & Hecksher-Sørensen, J., 2012, In: P L o S One. 7, 4, p. e35233Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Proteomic analyses reveal divergent ubiquitylation site patterns in murinetissues
Wagner, S. A., Beli, P., Weinert, B. T., Schölz, C. F., Kelstrup, C. D., Young, C., Nielsen, Michael Lund, Olsen, Jesper Velgaard, Brakebusch, Cord Herbert & Choudhary, Chunaram, 2012, In: Molecular & Cellular Proteomics.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Self-hydroxylation of the splicing factor lysyl hydroxylase, JMJD6
Mantri, M., Webby, C. J., Loik, N. D., Hamed, R. B., McDonough, M. A., McCullagh, J. S. O., Schofield, C. J., Wolf, A., Nielsen, Michael Lund & Böttger, A., 1 Jan 2012, In: MedChemComm. 3, 1, p. 80-85 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The molecular basis of ATM-dependent dimerization of the Mdc1 DNA damage checkpoint mediator.
Jungmichel, S., Clapperton, J. A., Janette, L., Hari, F. J., Spycher, C., Pavic, L., Li, J., Haire, L. F., Bonalli, M., Larsen, D. H., Lukas, C., Lukas, J., MacMillan, D., Nielsen, Michael Lund, Stucki, M. & Smerdon, S. J., 10 Jan 2012, In: Nucleic Acids Research. 40, 9, p. 4913-4928 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass
Povlsen, L. K., Beli, P., Wagner, S. A., Poulsen, S. L., Sylvestersen, K. B., Poulsen, J. W., Nielsen, Michael Lund, Bekker-Jensen, Simon Holst, Mailand, Niels & Choudhary, Chunaram, Oct 2012, In: Nature Cell Biology. 14, 10, p. 1089-98 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 13143239
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Biotin starvation causes mitochondrial protein hyperacetylation and partial rescue by the SIRT3-like deacetylase Hst4p
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An Optimized Shotgun Strategy for the Rapid Generation of Comprehensive Human Proteomes
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Integrative Characterization of the R6/2 Mouse Model of Huntington's Disease Reveals Dysfunctional Astrocyte Metabolism
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