Michael Lund Nielsen
Professor
Nielsen Group
Blegdamsvej 3B
2200 København N
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Liquid demixing of intrinsically disordered proteins is seeded by poly(ADP-ribose)
Altmeyer, M., Neelsen, K. J., Teloni, F., Pozdnyakova, I., Pellegrino, S., Grøfte, M., Rask, M. D., Streicher, W., Jungmichel, S., Nielsen, Michael Lund & Lukas, Jiri, 19 Aug 2015, In: Nature Communications. 6, p. 1-12 8088.Research output: Contribution to journal › Journal article › peer-review
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Characterizing ADP-Ribosylation Sites Using Af1521 Enrichment Coupled to ETD-Based Mass Spectrometry
Anagho, Holda Awah, Elsborg, Jonas Damgaard, Hendriks, Ivo Alexander, Buch-Larsen, Sara Charlotte & Nielsen, Michael Lund, 2023, Poly(ADP-Ribose) Polymerase: Methods and Protocols. Tulin, A. V. (ed.). Humana Press, p. 251-270 (Methods in Molecular Biology, Vol. 2609).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Protein Interaction Screening for the Ankyrin Repeats and Suppressor of Cytokine Signaling (SOCS) Box (ASB) Family Identify Asb11 as a Novel Endoplasmic Reticulum Resident Ubiquitin Ligase
Andresen, C. A., Smedegaard, S., Sylvestersen, K. B., Svensson, C., Iglesias Gato, Diego, Cazzamali, G., Nielsen, T. K., Nielsen, Michael Lund & Flores Morales, A., 24 Jan 2014, In: The Journal of Biological Chemistry. 289, 4, p. 2043-2054 12 p.Research output: Contribution to journal › Journal article › peer-review
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An Optimized Shotgun Strategy for the Rapid Generation of Comprehensive Human Proteomes
Bekker-Jensen, D. B., Kelstrup, C. D., Batth, Tanveer Singh, Buch-Larsen, Sara Charlotte, Haldrup, C., Bramsen, J. B., Sørensen, K. D., Høyer, S., Ørntoft, T. F., Andersen, C. L., Nielsen, Michael Lund & Olsen, Jesper Velgaard, 2017, In: Cell Systems. 4, 6, p. 587-599, e1-e4 18 p.Research output: Contribution to journal › Journal article › peer-review
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RNA-DNA sequence differences spell genetic code ambiguities
Bentin, Thomas & Nielsen, Michael Lund, 2013, In: Artificial DNA. 2, 3, p. 69-70 2 p.Research output: Contribution to journal › Journal article › peer-review
Analysis of in vivo histone methylation kinetics by Heavy Methyl SILAC
Bonaldi, T., Vitale, E., Nielsen, Michael Lund, Cox, J. & Mann, M., 2009, In: Amino Acids. 37, p. 66 1 p.Research output: Contribution to journal › Journal article › peer-review
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SUMOylation promotes protective responses to DNA-protein crosslinks
Borgermann, N., Ackermann, Leena, Schwertman, P., Hendriks, Ivo Alexander, Thijssen, K., Liu, Julio, Lans, H., Nielsen, Michael Lund & Mailand, Niels, 2019, In: E M B O Journal. 38, 17 p., e101496.Research output: Contribution to journal › Journal article › peer-review
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Mapping Physiological ADP-Ribosylation Using Activated Ion Electron Transfer Dissociation
Buch-Larsen, Sara Charlotte, Hendriks, Ivo Alexander, Lodge, J. M., Rykaer, M., Furtwängler, Benjamin, Shishkova, E., Westphall, M. S., Coon, J. J. & Nielsen, Michael Lund, 2020, In: Cell Reports. 32, 12, 17 p., 108176.Research output: Contribution to journal › Journal article › peer-review
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Can relative cleavage frequencies in peptides provide additional sequence information?
Budnik, B. A., Nielsen, Michael Lund, Olsen, Jesper Velgaard, Haselmann, K. F., Horth, P., Haehnel, W. & Zubarev, R. A., 2002, In: International Journal of Mass Spectrometry. 219, 1, p. 283-294 12 p.Research output: Contribution to journal › Journal article › peer-review
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DAXX adds a de novo H3.3K9me3 deposition pathway to the histone chaperone network
Carraro, Massimo, Hendriks, Ivo Alexander, Hammond, Colin, Solis-Mezarino, V., Völker-Albert, M., Elsborg, Jonas Damgaard, Weisser, Melanie, Spanos, C., Montoya, Guillermo, Rappsilber, J., Imhof, A., Nielsen, Michael Lund & Groth, Anja, 2023, In: Molecular Cell. 83, 7, p. 1075-1092.e9 28 p.Research output: Contribution to journal › Journal article › peer-review
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CDK-mediated activation of the SCF(FBXO) (28) ubiquitin ligase promotes MYC-driven transcription and tumourigenesis and predicts poor survival in breast cancer
Cepeda, D., Ng, H-F., Sharifi, H. R., Mahmoudi, S., Cerrato, V. S., Fredlund, E., Magnusson, K., Nilsson, H., Malyukova, A., Rantala, J., Klevebring, D., Viñals, F., Bhaskaran, N., Zakaria, S. M., Rahmanto, A. S., Grotegut, S., Nielsen, M. L., Szigyarto, C. A-K., Sun, D., Lerner, M. & 10 others, , 3 Jul 2013, In: E M B O Molecular Medicine (Online). 5, 7, p. 1067-1086 20 p.Research output: Contribution to journal › Journal article › peer-review
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Lysine acetylation targets protein complexes and co-regulates major cellular functions
Choudhary, Chunaram, Kumar, C., Gnad, F., Nielsen, Michael Lund, Rehman, M., Walther, T. C., Olsen, Jesper Velgaard & Mann, Matthias, 2009, In: Science. 325, 5942, p. 834-40 6 p.Research output: Contribution to journal › Journal article › peer-review
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Citrullination regulates pluripotency and histone H1 binding to chromatin
Christophorou, M. A., Castelo-Branco, G., Halley-Stott, R. P., Oliveira, C. S., Loos, R., Radzisheuskaya, A., Mowen, K. A., Bertone, P., Silva, J. C. R., Zernicka-Goetz, M., Nielsen, Michael Lund, Gurdon, J. B. & Kouzarides, T., 6 Mar 2014, In: Nature. 507, p. 104-108Research output: Contribution to journal › Journal article › peer-review
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Profiling ubiquitin signalling with UBIMAX reveals DNA damage- and SCFβ-Trcp1-dependent ubiquitylation of the actin-organizing protein Dbn1
S.Colding-Christensen, Camilla, Kakulidis, Ellen Sofia, Arroyo Gomez, Javier, Hendriks, Ivo Alexander, Arkinson, C., Fábián, Z., Gambus, A., Mailand, Niels, Duxin, Julien & Nielsen, Michael Lund, 2023, In: Nature Communications. 14, 19 p., 8293.Research output: Contribution to journal › Journal article › peer-review
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Transient suppression of SUMOylation in embryonic stem cells generates embryo-like structures
Cossec, J. C., Traboulsi, T., Sart, S., Loe-Mie, Y., Guthmann, M., Hendriks, Ivo Alexander, Theurillat, I., Nielsen, Michael Lund, Torres-Padilla, M. E., Baroud, C. N. & Dejean, A., 2023, In: Cell Reports. 42, 4, 27 p., 112380.Research output: Contribution to journal › Journal article › peer-review
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Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level
Danielsen, J. M. R., Sylvestersen, K. B., Bekker-Jensen, Simon Holst, Szklarczyk, D., Poulsen, J. W., Horn, H., Jensen, Lars Juhl, Mailand, Niels & Nielsen, Michael Lund, 1 Mar 2011, In: Molecular and Cellular Proteomics. 10, 3, p. M110.003590Research output: Contribution to journal › Journal article › peer-review
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Citrullination modulates oligodendrocyte differentiation
Falcao, A., Meijer, M., Rinwa, P., Cummings, T., Varas, M., Liang, J., Casaccia, P., Christophorou, M., Nielsen, Michael Lund, Ernfors, P. & Castelo-Branco, G., 2017, In: Glia. 65, S1, p. E389 1 p.Research output: Contribution to journal › Conference abstract in journal › peer-review
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PAD2-Mediated Citrullination Contributes to Efficient Oligodendrocyte Differentiation and Myelination
Falcão, A. M., Meijer, M., Scaglione, A., Rinwa, P., Agirre, E., Liang, J., Buch-Larsen, Sara Charlotte, Heskol, A., Frawley, R., Klingener, M., Varas-Godoy, M., Raposo, A. A. S. F., Ernfors, P., Castro, D. S., Nielsen, Michael Lund, Casaccia, P. & Castelo-Branco, G., 2019, In: Cell Reports. 27, 4, p. 1090-1102.e10Research output: Contribution to journal › Journal article › peer-review
Analytical Utility of Small Neutral Losses from Reduced Species in Electron Capture Dissociation Studied Using SwedECD Database
Falth, M., Savitski, M. M., Nielsen, Michael Lund, Kjeldsen, F., Andren, P. E. & Zubarev, R. A., 2008, In: Analytical Chemistry. 80, 21, p. 8089-8094 6 p.Research output: Contribution to journal › Journal article › peer-review
SwedCAD, a database of annotated high-mass accuracy MS/MS spectra of tryptic peptides
Falth, M., Savitski, M. M., Nielsen, Michael Lund, Kjeldsen, F., Andren, P. E. & Zubarev, R. A., 2007, In: Journal of Proteome Research. 6, 10, p. 4063-4067 5 p.Research output: Contribution to journal › Journal article › peer-review
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Serine ADP-ribosylation in Drosophila provides insights into the evolution of reversible ADP-ribosylation signalling
Fontana, P., Buch-Larsen, Sara Charlotte, Suyari, O., Smith, R., Suskiewicz, M. J., Schützenhofer, K., Ariza, A., Rack, J. G. M., Nielsen, Michael Lund & Ahel, I., 2023, In: Nature Communications. 14, 1, 3200.Research output: Contribution to journal › Journal article › peer-review
De novo peptide sequencing and identification with precision mass spectrometry
Frank, A. M., Savitski, M. M., Nielsen, Michael Lund, Zubarev, R. A. & Pevzner, P. A., 2007, In: Journal of Proteome Research. 6, 1, p. 114-123 10 p.Research output: Contribution to journal › Journal article › peer-review
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Pdx1 is post-translationally modified in vivo and serine 61 is the principal site of phosphorylation
Frogne, T., Sylvestersen, K. B., Kubicek, S., Nielsen, Michael Lund & Hecksher-Sørensen, J., 2012, In: P L o S One. 7, 4, p. e35233Research output: Contribution to journal › Journal article › peer-review
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The ubiquitin ligase RFWD3 is required for translesion DNA synthesis
Gallina, I., Hendriks, Ivo Alexander, Hoffmann, Saskia, Larsen, N. B., Johansen, Joachim, S.Colding-Christensen, Camilla, Schubert, Lisa, Sellés Baiget, Selene, Fábián, Z., Kühbacher, U., Gao, A. O., Räschle, M., Rasmussen, Simon, Nielsen, Michael Lund, Mailand, Niels & Duxin, Julien, 2021, In: Molecular Cell. 81, 3, p. 442-458.e9 27 p.Research output: Contribution to journal › Journal article › peer-review
ID: 13143239
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Biotin starvation causes mitochondrial protein hyperacetylation and partial rescue by the SIRT3-like deacetylase Hst4p
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An Optimized Shotgun Strategy for the Rapid Generation of Comprehensive Human Proteomes
Research output: Contribution to journal › Journal article › peer-review
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246
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Integrative Characterization of the R6/2 Mouse Model of Huntington's Disease Reveals Dysfunctional Astrocyte Metabolism
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