SCO-ping out the mechanisms underlying the etiology of hydrocephalus
Research output: Contribution to journal › Review › Research › peer-review
The heterogeneous nature of congenital hydrocephalus has hampered our understanding of the molecular basis of this common clinical problem. However, disease gene identification and characterization of multiple transgenic mouse models has highlighted the importance of the subcommissural organ (SCO) and the ventricular ependymal (vel) cells. Here, we review how altered development and function of the SCO and vel cells contributes to hydrocephalus.
Original language | English |
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Journal | Physiology |
Volume | 24 |
Issue number | 2 |
Pages (from-to) | 117-126 |
Number of pages | 10 |
ISSN | 1548-9213 |
DOIs | |
Publication status | Published - Apr 2009 |
Externally published | Yes |
ID: 319874068