Mining electronic health records: towards better research applications and clinical care
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Mining electronic health records : towards better research applications and clinical care. / Jensen, Peter B; Jensen, Lars J; Brunak, Søren.
In: Nature Reviews. Genetics, Vol. 13, No. 6, 2012, p. 395-405.Research output: Contribution to journal › Journal article › peer-review
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TY - JOUR
T1 - Mining electronic health records
T2 - towards better research applications and clinical care
AU - Jensen, Peter B
AU - Jensen, Lars J
AU - Brunak, Søren
PY - 2012
Y1 - 2012
N2 - Clinical data describing the phenotypes and treatment of patients represents an underused data source that has much greater research potential than is currently realized. Mining of electronic health records (EHRs) has the potential for establishing new patient-stratification principles and for revealing unknown disease correlations. Integrating EHR data with genetic data will also give a finer understanding of genotype-phenotype relationships. However, a broad range of ethical, legal and technical reasons currently hinder the systematic deposition of these data in EHRs and their mining. Here, we consider the potential for furthering medical research and clinical care using EHR data and the challenges that must be overcome before this is a reality.
AB - Clinical data describing the phenotypes and treatment of patients represents an underused data source that has much greater research potential than is currently realized. Mining of electronic health records (EHRs) has the potential for establishing new patient-stratification principles and for revealing unknown disease correlations. Integrating EHR data with genetic data will also give a finer understanding of genotype-phenotype relationships. However, a broad range of ethical, legal and technical reasons currently hinder the systematic deposition of these data in EHRs and their mining. Here, we consider the potential for furthering medical research and clinical care using EHR data and the challenges that must be overcome before this is a reality.
KW - Biomedical Research
KW - Electronic Health Records
KW - Genetic Association Studies
KW - Humans
KW - Information Dissemination
KW - Medical Records Systems, Computerized
KW - Patient Care
KW - Primary Health Care
KW - Public Health
U2 - 10.1038/nrg3208
DO - 10.1038/nrg3208
M3 - Journal article
C2 - 22549152
VL - 13
SP - 395
EP - 405
JO - Nature Reviews. Genetics
JF - Nature Reviews. Genetics
SN - 1471-0056
IS - 6
ER -
ID: 40288777