Thomas Kruse

Thomas Kruse

Associate Professor


  1. Published

    In vivo quantitative phosphoproteomic profiling identifies novel regulators of castration-resistant prostate cancer growth

    Jiang, N., Hjorth-Jensen, K., Hekmat, O., Iglesias Gato, Diego, Kruse, Thomas, Wang, C., Wei, W., Ke, B., Yan, B., Niu, Y., Olsen, Jesper Velgaard & Flores Morales, A., 2015, In: Oncogene. 34, p. 2764–2776 13 p.

    Research output: Contribution to journalJournal articlepeer-review

  2. Published

    A Consensus Binding Motif for the PP4 Protein Phosphatase

    Ueki, Y., Kruse, Thomas, Weisser, Melanie, Sundell, G. N., Larsen, Marie Sofie Yoo, Mendez, B. L., Jenkins, N. P., Garvanska, Dimitriya Hristoforova, Cressey, L., Zhang, G., Davey, N., Montoya, Guillermo, Ivarsson, Y., Kettenbach, A. N. & Nilsson, Jakob, 2019, In: Molecular Cell. 76, 6, p. 953-964.e6

    Research output: Contribution to journalJournal articlepeer-review

  3. Published

    A Conserved Motif Provides Binding Specificity to the PP2A-B56 Phosphatase

    Hertz, Emil Peter Thrane, Kruse, Thomas, Davey, N. E., López-Méndez, B., Sigurdsson, J. O., Montoya, Guillermo, Olsen, Jesper Velgaard & Nilsson, Jakob, 2016, In: Molecular Cell. 63, 4, p. 686-695 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  4. Published

    A complex of BRCA2 and PP2A-B56 is required for DNA repair by homologous recombination

    Ambjørn, Sara Marie, Duxin, Julien, Hertz, Emil Peter Thrane, Nasa, I., Duro, Joana Maria, Kruse, Thomas, Lopez-Mendez, B., Rymarczyk, B., Cressey, L. E., van Overeem Hansen, T., Kettenbach, A. N., Østergaard, Vibe Hallundbæk, Lisby, Michael & Nilsson, Jakob, 2021, In: Nature Communications. 12, 1, 11 p., 5748.

    Research output: Contribution to journalJournal articlepeer-review

  5. Published

    A direct role of Mad1 in the spindle assembly checkpoint beyond Mad2 kinetochore recruitment

    Kruse, Thomas, Larsen, Marie Sofie Yoo, Sedgwick, G. G., Sigurdsson, J. O., Streicher, W., Olsen, Jesper Velgaard & Nilsson, Jakob, 29 Jan 2014, In: E M B O Reports. 15, p. 282-290

    Research output: Contribution to journalJournal articlepeer-review

  6. Published

    A highly conserved pocket on PP2A-B56 is required for hSgo1 binding and cohesion protection during mitosis

    Ueki, Y., Hadders, M. A., Weisser, Melanie, Nasa, I., Sotelo-Parrilla, P., Cressey, L. E., Gupta, T., Hertz, Emil Peter Thrane, Kruse, Thomas, Montoya, Guillermo, Jeyaprakash, A. A., Kettenbach, A., Lens, S. M. A. & Nilsson, Jakob, 2021, In: EMBO Reports. 22, 7, 13 p., e52295.

    Research output: Contribution to journalJournal articlepeer-review

  7. Published

    Actin homolog MreB and RNA polymerase interact and are both required for chromosome segregation in Escherichia coli

    Kruse, Thomas, Blagoev, B., Løbner-Olesen, Anders, Wachi, M., Sasaki, K., Iwai, N., Mann, Matthias & Gerdes, K., 1 Jan 2006, In: Genes & Development. 20, 1, p. 113-124 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  8. Published

    Bub1 positions Mad1 close to KNL1 MELT repeats to promote checkpoint signalling

    Zhang, G., Kruse, Thomas, López-Méndez, B., Sylvestersen, K. B., Garvanska, Dimitriya Hristoforova, Schopper, S., Nielsen, Michael Lund & Nilsson, Jakob, 12 Jun 2017, In: Nature Communications. 8, 12 p., 15822.

    Research output: Contribution to journalJournal articlepeer-review

  9. Published

    Cryo-EM structures of PP2A:B55–FAM122A and PP2A:B55–ARPP19

    Padi, S. K. R., Vos, M. R., Godek, R. J., Fuller, J. R., Kruse, Thomas, Hein, J. B., Nilsson, Jakob, Kelker, M. S., Page, R. & Peti, W., 2024, In: Nature. 625, 7993, p. 195-203 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  10. Published

    Direct binding between BubR1 and B56-PP2A phosphatase complexes regulate mitotic progression

    Kruse, Thomas, Zhang, G., Larsen, Marie Sofie Yoo, Lischetti, T., Streicher, W., Nielsen, T. K., Bjørn, S. P. & Nilsson, Jakob, 23 Jan 2013, In: Journal of Cell Science. 126, p. 1086-1092 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  11. Published

    Distinct kinetics of serine and threonine dephosphorylation are essential for mitosis

    Hein, J. B., Hertz, Emil Peter Thrane, Garvanska, Dimitriya Hristoforova, Kruse, Thomas & Nilsson, Jakob, 2017, In: Nature Cell Biology. 19, p. 1433-1440

    Research output: Contribution to journalJournal articlepeer-review

  12. Dysfunctional MreB inhibits chromosome segregation in Escherichia coli

    Kruse, Thomas, Møller-Jensen, J., Løbner-Olesen, Anders & Gerdes, K., 2003, In: E M B O Journal. 22, 19, p. 5283-5292 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  13. Published

    Efficient mitotic checkpoint signaling depends on integrated activities of Bub1 and the RZZ complex

    Zhang, G., Kruse, Thomas, Guasch Boldú, C., Garvanska, Dimitriya Hristoforova, Coscia, F., Mann, Matthias, Barisic, Marin & Nilsson, Jakob, 2019, In: E M B O Journal. 38, 7, e100977.

    Research output: Contribution to journalJournal articlepeer-review

  14. Published
  15. Published

    K27-linked ubiquitylation promotes p97 substrate processing and is essential for cell proliferation

    Shearer, Robert Francis, Typas, D., Coscia, F., Schovsbo, Sofie Ulfbeck, Kruse, Thomas, Mund, Andreas & Mailand, Niels, 2022, In: E M B O Journal. 41, 9, 18 p., e110145.

    Research output: Contribution to journalJournal articlepeer-review

  16. Published

    Large scale discovery of coronavirus-host factor protein interaction motifs reveals SARS-CoV-2 specific mechanisms and vulnerabilities

    Kruse, T., Benz, C., Garvanska, D. H., Lindqvist, R., Mihalic, F., Coscia, F., Inturi, R., Sayadi, A., Simonetti, L., Nilsson, E., Ali, M., Kliche, J., Moliner Morro, A., Mund, A., Andersson, E., McInerney, G., Mann, M., Jemth, P., Davey, N. E., Överby, A. K. & 2 others, Nilsson, Jakob & Ivarsson, Y., 2021, In: Nature Communications. 12, 1, 13 p., 6761.

    Research output: Contribution to journalJournal articlepeer-review

  17. Published

    Mechanisms of site-specific dephosphorylation and kinase opposition imposed by PP2A regulatory subunits

    Kruse, Thomas, Gnosa, S. P., Nasa, I., Garvanska, Dimitriya Hristoforova, Hein, J. B., Nguyen, H., Samsøe-Petersen, Jacob, Lopez-Mendez, B., Hertz, Emil Peter Thrane, Schwarz, J., Pena, H. S., Nikodemus, D., Kveiborg, Marie, Kettenbach, A. N. & Nilsson, Jakob, 2020, In: EMBO Journal. 39, 18 p., e103695.

    Research output: Contribution to journalJournal articlepeer-review

  18. Published
  19. Published

    Phosphatase specificity principles uncovered by MRBLE:Dephos and global substrate identification

    Hein, J. B., Nguyen, H. T., Garvanska, Dimitriya Hristoforova, Nasa, I., Kruse, Thomas, Feng, Y., Lopez Mendez, B., Davey, N., Kettenbach, A. N., Fordyce, P. M. & Nilsson, Jakob, 2023, In: Molecular Systems Biology. 19, 17 p., e11782.

    Research output: Contribution to journalJournal articlepeer-review

  20. Published

    Quantitative kinase and phosphatase profiling reveal that CDK1 phosphorylates PP2Ac to promote mitotic entry

    Nasa, I., Cressey, L. E., Kruse, Thomas, Hertz, Emil Peter Thrane, Gui, J., Graves, L. M., Nilsson, Jakob & Kettenbach, A. N., 2020, In: Science Signaling. 13, 648, 15 p., eaba7823.

    Research output: Contribution to journalJournal articlepeer-review

  21. Published

    Response to Raaijmakers & Medema

    Zhang, G., Kruse, Thomas, Boldú, C. G., Garvanska, Dimitriya Hristoforova, Coscia, F., Mann, Matthias, Barisic, Marin & Nilsson, Jakob, 2019, In: The EMBO Journal. 38, 22, 5 p., e103547.

    Research output: Contribution to journalComment/debate

  22. Published

    Spatial separation of phosphatase and kinase activity within the Bub complex is required for proper mitosis

    Wang, L., Kruse, Thomas, López-Méndez, B., Zhang, Y., Song, C., Zhu, L., Li, B., Fang, J., Lu, Z., Nilsson, Jakob & Zhang, G., 2023, In: Journal of Molecular Cell Biology. 14, 11, 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  23. Published

    The Ebola Virus Nucleoprotein Recruits the Host PP2A-B56 Phosphatase to Activate Transcriptional Support Activity of VP30

    Kruse, Thomas, Biedenkopf, N., Hertz, Emil Peter Thrane, Dietzel, E., Stalmann, G., López-Méndez, B., Davey, N. E., Nilsson, Jakob & Becker, S., 4 Jan 2018, In: Molecular Cell. 69, 1, p. 136-145 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  24. Published

    The SUMO–NIP45 pathway processes toxic DNA catenanes to prevent mitotic failure

    Hertz, Emil Peter Thrane, Alonso de Vega, Ignacio, Kruse, Thomas, Wang, Y., Hendriks, Ivo Alexander, Bizard, A. H., Eugui-Anta, A., Hay, R. T., Nielsen, Michael Lund, Nilsson, Jakob, Hickson, Ian David & Mailand, Niels, 2023, In: Nature Structural and Molecular Biology. 30, p. 1303-1313

    Research output: Contribution to journalJournal articlepeer-review

  25. Published

    The morphogenetic MreBCD proteins of Escherichia coli form an essential membrane-bound complex

    Kruse, Thomas, Bork-Jensen, J. & Gerdes, K., Jan 2005, In: Molecular Microbiology. 55, 1, p. 78-89 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  26. Published

    TopBP1 is required at mitosis to reduce transmission of DNA damage to G1 daughter cells

    Pedersen, R. T., Kruse, Thomas, Nilsson, Jakob, Østergaard, Vibe Hallundbæk & Lisby, Michael, 2015, In: Journal of Cell Biology. 210, 4, p. 565-582 18 p.

    Research output: Contribution to journalJournal articlepeer-review

ID: 34503674