Saskia Hoffmann

Saskia Hoffmann

Associate Professor

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    ORCID: 0000-0003-4835-0504

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    1. p53 and cell cycle dependent transcription of kinesin family member 23 (KIF23) is controlled via a CHR promoter element bound by DREAM and MMB complexes

      Fischer, M., Grundke, I., Sohr, S., Quaas, M., Hoffmann, Saskia, Knörck, A., Gumhold, C. & Rother, K., 2013, In: PLoS ONE. 8, 5, p. e63187

      Research output: Contribution to journal › Journal article › Research › peer-review

    2. Published

      ZUFSP Deubiquitylates K63-Linked Polyubiquitin Chains to Promote Genome Stability

      Haahr, Peter Thorlund, Borgermann, N., Guo, X., Typas, D., Achuthankutty, D., Hoffmann, Saskia, Shearer, Robert Francis, Sixma, T. K. & Mailand, Niels, 2018, In: Molecular Cell. 70, 1, p. 165-174

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Published

      VCF1 is a p97/VCP cofactor promoting recognition of ubiquitylated p97-UFD1-NPL4 substrates

      Mirsanaye, Ann Schirin, Hoffmann, Saskia, Weisser, Melanie, Mund, Andreas, Lopez Mendez, B., Typas, D., van den Boom, J., Benedict, Bente, Hendriks, Ivo Alexander, Nielsen, Michael Lund, Meyer, H., Duxin, Julien, Montoya, Guillermo & Mailand, Niels, 2024, In: Nature Communications. 15, 1, 16 p., 2459.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      The ubiquitin ligase RFWD3 is required for translesion DNA synthesis

      Gallina, I., Hendriks, Ivo Alexander, Hoffmann, Saskia, Larsen, N. B., Johansen, Joachim, S.Colding-Christensen, Camilla, Schubert, Lisa, Sellés Baiget, Selene, Fábián, Z., Kühbacher, U., Gao, A. O., Räschle, M., Rasmussen, Simon, Nielsen, Michael Lund, Mailand, Niels & Duxin, Julien, 2021, In: Molecular Cell. 81, 3, p. 442-458.e9 27 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      TRAIP is a PCNA-binding ubiquitin ligase that protects genome stability after replication stress

      Hoffmann, Saskia, Smedegaard, S., Nakamura, K., Mortuza, G. B., Räschle, M., Ibañez de Opakua, A., Oka, Y., Feng, Y., Blanco, F. J., Mann, Matthias, Montoya, Guillermo, Groth, Anja, Bekker-Jensen, Simon Holst & Mailand, Niels, 4 Jan 2016, In: The Journal of Cell Biology. 212, 1, p. 63-75

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      TRAIP drives replisome disassembly and mitotic DNA repair synthesis at sites of incomplete DNA replication

      Sonneville, R., Bhowmick, Rahul, Hoffmann, Saskia, Mailand, Niels, Hickson, Ian David & Labib, K., 2019, In: eLife. 8, 19 p., e48686.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      SCFCyclin F-dependent degradation of CDC6 suppresses DNA re-replication

      Walter, D., Hoffmann, Saskia, Komseli, E., Rappsilber, J., Gorgoulis, V. & Sørensen, Claus Storgaard, 2016, In: Nature Communications. 7, 10 p., 10530.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      SCAI promotes error-free repair of DNA interstrand crosslinks via the Fanconi anemia pathway

      Schubert, Lisa, Hendriks, Ivo Alexander, Hertz, Emil Peter Thrane, Wu, Wei, Sellés Baiget, Selene, Hoffmann, Saskia, Bagge, Keerthana Stine Viswalingam, Gallina, I., Pentakota, S., Benedict, Bente, Johansen, Joachim, Apelt, K., Luijsterburg, M. S., Rasmussen, Simon, Lisby, Michael, Liu, Ying, Nielsen, Michael Lund, Mailand, Niels & Duxin, Julien, 2022, In: EMBO Reports. 23, 4, 20 p., e53639.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      Regulation of ETAA1-mediated ATR activation couples DNA replication fidelity and genome stability

      Achuthankutty, D., Thakur, R. S., Haahr, Peter Thorlund, Hoffmann, Saskia, Drainas, A. P., Bizard, A. H., Weischenfeldt, Joachim Lütken, Hickson, Ian David & Mailand, Niels, 2019, In: The Journal of Cell Biology. 218, 12, 11 p., 3943.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      RADX interacts with single-stranded DNA to promote replication fork stability

      Schubert, Lisa, Ho, T., Hoffmann, Saskia, Haahr, Peter Thorlund, Guérillon, C. & Mailand, Niels, Nov 2017, In: EMBO Reports. 18, 11, p. 1991-2003 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      Histone H1 couples initiation and amplification of ubiquitin signalling after DNA damage

      Thorslund, T., Ripplinger, A., Hoffmann, Saskia, Wild, T., Uckelmann, M., Villumsen, B., Narita, Takeo, Sixma, T. K., Choudhary, Chunaram, Bekker-Jensen, Simon Holst & Mailand, Niels, 19 Nov 2015, In: Nature. 527, 7578, p. 389-93 5 p.

      Research output: Contribution to journal › Letter › Research › peer-review

    12. Published

      FAM111 protease activity undermines cellular fitness and is amplified by gain-of-function mutations in human disease

      Hoffmann, Saskia, Pentakota, S., Mund, Andreas, Haahr, Peter Thorlund, Coscia, F., Gallo, M., Mann, Matthias, Taylor, Nicholas M I & Mailand, Niels, 2020, In: EMBO Reports. 21, 10, 14 p., e50662.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      Cyclin F suppresses B-Myb activity to promote cell cycle checkpoint control

      Klein, D. K., Hoffmann, Saskia, Ahlskog, J. K., O'Hanlon, K., Quaas, M., Larsen, Brian Daniel, Rolland, B., Rösner, Heike Ilona, Walter, D., Kousholt, A. N., Menzel, T., Lees, M., Johansen, Jens Vilstrup, Rappsilber, J., Engeland, K. & Sørensen, Claus Storgaard, 2015, In: Nature Communications. 6, p. 5800

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      Activation of the ATR kinase by the RPA-binding protein ETAA1

      Haahr, Peter Thorlund, Hoffmann, Saskia, Tollenaere, M. A. X., Ho, T., Toledo Lazaro, L. I., Mann, Matthias, Bekker-Jensen, Simon Holst, Räschle, M. & Mailand, Niels, Nov 2016, In: Nature Cell Biology. 18, 11, p. 1196–1207

      Research output: Contribution to journal › Journal article › Research › peer-review

    ID: 40814530