Sara Charlotte Buch-Larsen

Sara Charlotte Buch-Larsen

Assistant Professor


  1. 2024
  2. E-pub ahead of print

    A quantitative and site-specific atlas of the citrullinome reveals widespread existence of citrullination and insights into PADI4 substrates

    Stripp, Alexandra, Hendriks, Ivo Alexander, Elsborg, Jonas Damgaard, Buch-Larsen, Sara Charlotte, Nielsen, C. H., Terslev, L., Kirsch, Rebecca, Damgaard, D., Doncheva, Nadezhda Tsankova, Lennartsson, Caroline Linnea Elin, Rykær, M., Jensen, Lars Juhl, Christophorou, M. A. & Nielsen, Michael Lund, 2024, (E-pub ahead of print) In: Nature Structural and Molecular Biology.

    Research output: Contribution to journalJournal articlepeer-review

  3. 2023
  4. Published

    Characterizing ADP-Ribosylation Sites Using Af1521 Enrichment Coupled to ETD-Based Mass Spectrometry

    Anagho, Holda Awah, Elsborg, Jonas Damgaard, Hendriks, Ivo Alexander, Buch-Larsen, Sara Charlotte & Nielsen, Michael Lund, 2023, Poly(ADP-Ribose) Polymerase: Methods and Protocols. Tulin, A. V. (ed.). Humana Press, p. 251-270 (Methods in Molecular Biology, Vol. 2609).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  5. Published

    Regulation of Rad52-dependent replication fork recovery through serine ADP-ribosylation of PolD3

    Richards, F., Llorca-Cardenosa, M. J., Langton, J., Buch-Larsen, Sara Charlotte, Shamkhi, N. F., Sharma, A. B., Nielsen, Michael Lund & Lakin, N. D., 2023, In: Nature Communications. 14, 1, 14 p., 4310.

    Research output: Contribution to journalJournal articlepeer-review

  6. Published

    Serine ADP-ribosylation in Drosophila provides insights into the evolution of reversible ADP-ribosylation signalling

    Fontana, P., Buch-Larsen, Sara Charlotte, Suyari, O., Smith, R., Suskiewicz, M. J., Schützenhofer, K., Ariza, A., Rack, J. G. M., Nielsen, Michael Lund & Ahel, I., 2023, In: Nature Communications. 14, 1, 3200.

    Research output: Contribution to journalJournal articlepeer-review

  7. Published

    Substituting sedentary time with sleep or physical activity and subsequent weight-loss maintenance

    Buch-Larsen, Sara Charlotte, O'Driscoll, R., Horgan, G., Mikkelsen, M. L. K., Specht, I. O., Rohde, J. F., Turicchi, J., Santos, I., Encantado, J., Duarte, C., Ward, L. C., Palmeira, A. L., Stubbs, R. J. & Heitmann, Berit, 2023, In: Obesity. 31, 2, p. 515-524 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  8. 2021
  9. Published

    Chemical genetics and proteome-wide site mapping reveal cysteine MARylation by PARP-7 on immune-relevant protein targets

    Rodriguez, K. M., Buch-Larsen, Sara Charlotte, Kirby, I. T., Siordia, I. R., Hutin, D., Rasmussen, M., Grant, D. M., David, L. L., Matthews, J., Nielsen, Michael Lund & Cohen, M. S., 2021, In: eLife. 10, 35 p., e60480.

    Research output: Contribution to journalJournal articlepeer-review

  10. Published

    Site-specific phosphorylation of PSD-95 dynamically regulates the postsynaptic density as observed by phase separation

    Vistrup-Parry, M., Chen, X., Johansen, T. L., Bach, S., Buch-Larsen, Sara Charlotte, Bartling, Christian Reinhard Otto, Ma, C., Clemmensen, L. S., Nielsen, Michael Lund, Zhang, M. & Strømgaard, Kristian, 2021, In: iScience. 24, 11, 103268.

    Research output: Contribution to journalJournal articlepeer-review

  11. Published

    Temporal and site-specific adp-ribosylation dynamics upon different genotoxic stresses

    Buch-Larsen, Sara Charlotte, Stripp, Alexandra, Hendriks, Ivo Alexander & Nielsen, Michael Lund, 2021, In: Cells. 10, 11, 16 p., 2927.

    Research output: Contribution to journalJournal articlepeer-review

  12. Published

    The regulatory landscape of the human HPF1-and ARH3-dependent ADP-ribosylome

    Hendriks, Ivo Alexander, Buch-Larsen, Sara Charlotte, Prokhorova, E., Elsborg, Jonas Damgaard, Stripp, Alexandra, Zhu, K., Ahel, D., Lukas, Claudia, Ahel, I. & Nielsen, Michael Lund, 2021, In: Nature Communications. 12, 1, 16 p., 5893.

    Research output: Contribution to journalJournal articlepeer-review

  13. Published

    Three-year intervention effects on food and beverage intake— results from the quasi-experimental copenhagen school child intervention study (Coscis)

    Ren, X., Jensen, B. W., Buch-Larsen, Sara Charlotte, Rohde, J. F., Specht, I. O., Nielsen, B. M., Husby, I., Bugge, A., Andersen, L. B., Trolle, E. & Heitmann, Berit, 2021, In: International Journal of Environmental Research and Public Health. 18, 19, 12 p., 10543.

    Research output: Contribution to journalJournal articlepeer-review

  14. 2020
  15. Published

    Data imputation and body weight variability calculation using linear and nonlinear methods in data collected from digital smart scales: Simulation and validation study

    Turicchi, J., O'Driscoll, R., Finlayson, G., Duarte, C., Palmeira, A. L., Buch-Larsen, Sara Charlotte, Heitmann, Berit & James Stubbs, R., 2020, In: JMIR mHealth and uHealth. 8, 9, e17977.

    Research output: Contribution to journalJournal articlepeer-review

  16. Published

    Mapping Physiological ADP-Ribosylation Using Activated Ion Electron Transfer Dissociation

    Buch-Larsen, Sara Charlotte, Hendriks, Ivo Alexander, Lodge, J. M., Rykaer, M., Furtwängler, Benjamin, Shishkova, E., Westphall, M. S., Coon, J. J. & Nielsen, Michael Lund, 2020, In: Cell Reports. 32, 12, 17 p., 108176.

    Research output: Contribution to journalJournal articlepeer-review

  17. Published

    Treacle controls the nucleolar response to rDNA breaks via TOPBP1 recruitment and ATR activation

    Mooser, C., Symeonidou, I., Leimbacher, P., Ribeiro, A., Shorrocks, A. K., Jungmichel, S., Buch-Larsen, Sara Charlotte, Knechtle, K., Jasrotia, A., Zurbriggen, D., Jeanrenaud, A., Leikauf, C., Fink, D., Nielsen, Michael Lund, Blackford, A. N. & Stucki, M., 2020, In: Nature Communications. 11, 16 p., 123.

    Research output: Contribution to journalJournal articlepeer-review

  18. 2019
  19. Published

    An advanced strategy for comprehensive profiling of ADP-ribosylation sites using mass spectrometry-based proteomics

    Hendriks, Ivo Alexander, Buch-Larsen, Sara Charlotte & Nielsen, Michael Lund, 2019, In: Molecular and Cellular Proteomics. 18, 5, p. 1010-1026

    Research output: Contribution to journalJournal articlepeer-review

  20. Published

    PAD2-Mediated Citrullination Contributes to Efficient Oligodendrocyte Differentiation and Myelination

    Falcão, A. M., Meijer, M., Scaglione, A., Rinwa, P., Agirre, E., Liang, J., Buch-Larsen, Sara Charlotte, Heskol, A., Frawley, R., Klingener, M., Varas-Godoy, M., Raposo, A. A. S. F., Ernfors, P., Castro, D. S., Nielsen, Michael Lund, Casaccia, P. & Castelo-Branco, G., 2019, In: Cell Reports. 27, 4, p. 1090-1102.e10

    Research output: Contribution to journalJournal articlepeer-review

  21. 2018
  22. Published
  23. 2017
  24. Published

    An Optimized Shotgun Strategy for the Rapid Generation of Comprehensive Human Proteomes

    Bekker-Jensen, D. B., Kelstrup, C. D., Batth, Tanveer Singh, Buch-Larsen, Sara Charlotte, Haldrup, C., Bramsen, J. B., Sørensen, K. D., Høyer, S., Ørntoft, T. F., Andersen, C. L., Nielsen, Michael Lund & Olsen, Jesper Velgaard, 2017, In: Cell Systems. 4, 6, p. 587-599, e1-e4 18 p.

    Research output: Contribution to journalJournal articlepeer-review

  25. Published

    Proteome-Wide Identification of In Vivo ADP-Ribose Acceptor Sites by Liquid Chromatography-Tandem Mass Spectrometry

    Buch-Larsen, Sara Charlotte, Leutert, M., Bilan, V., Martello, R., Jungmichel, S., Young, C., Hottiger, M. O. & Nielsen, Michael Lund, 2017, Poly(ADP-Ribose) Polymerase. Tulin, A. V. (ed.). Humana Press, Vol. 1608. p. 149-162 14 p. (Methods in molecular biology (Clifton, N.J.)).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  26. 2016
  27. Published

    Proteome-wide identification of the endogenous ADP-ribosylome of mammalian cells and tissue

    Martello, R., Leutert, M., Jungmichel, S., Bilan, V., Buch-Larsen, Sara Charlotte, Young, C., Hottiger, M. O. & Nielsen, Michael Lund, 1 Oct 2016, In: Nature Communications. 7, 13 p., 12917.

    Research output: Contribution to journalJournal articlepeer-review

  28. Published

    Proteome-wide analysis of arginine monomethylation reveals widespread occurrence in human cells

    Buch-Larsen, Sara Charlotte, Sylvestersen, K. B., Mund, Andreas, Lyon, D., Mullari, M., Madsen, M. V., Daniel, J. A., Jensen, Lars Juhl & Nielsen, Michael Lund, 30 Aug 2016, In: Science Signaling. 9, 443, 14 p., rs9.

    Research output: Contribution to journalJournal articlepeer-review

  29. 2015
  30. Published

    Biotin starvation causes mitochondrial protein hyperacetylation and partial rescue by the SIRT3-like deacetylase Hst4p

    Madsen, C. T., Sylvestersen, K. B., Young, C., Buch-Larsen, Sara Charlotte, Poulsen, J. W., Andersen, M. A., Palmqvist, E. A., Hey-Mogensen, M., Jensen, P. B., Treebak, Jonas Thue, Lisby, Michael & Nielsen, Michael Lund, 2015, In: Nature Communications. 6, 12 p., 7726.

    Research output: Contribution to journalJournal articlepeer-review

ID: 67572706