Niels Mailand

Niels Mailand

Professor, head of research, Professor


  1. 2009
  2. USP7 counteracts SCFbetaTrCP- but not APCCdh1-mediated proteolysis of Claspin

    Faustrup, H., Bekker-Jensen, Simon Holst, Bartek, J., Lukas, Jiri & Mailand, Niels, 2009, In: Journal of Cell Biology. 184, 1, p. 13-9 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 2008
  4. Phosphorylation of SDT repeats in the MDC1 N terminus triggers retention of NBS1 at the DNA damage-modified chromatin

    Melander, F., Bekker-Jensen, Simon Holst, Falck, J., Bartek, J., Mailand, Niels & Lukas, Jiri, 21 Apr 2008, In: Journal of Cell Biology. 181, 2, p. 213-26 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. 2007
  6. Published

    Human Xip1 (C2orf13) is a novel regulator of cellular responses to DNA strand breaks

    Bekker-Jensen, Simon Holst, Fugger, K., Danielsen, J. R., Gromova, I., Sehested, M., Celis, J., Bartek, J., Lukas, Jiri & Mailand, Niels, 6 Jul 2007, In: Journal of Biological Chemistry. 282, 27, p. 19638-43 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins

    Mailand, Niels, Bekker-Jensen, Simon Holst, Faustrup, H., Melander, F., Bartek, J., Lukas, Claudia & Lukas, Jiri, 2007, In: Cell. 131, 5, p. 887-900 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. 2006
  9. TOPping up ATR activity

    Bartek, J. & Mailand, Niels, 10 Mar 2006, In: Cell. 124, 5, p. 888-90 3 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  10. Claspin operates downstream of TopBP1 to direct ATR signaling towards Chk1 activation

    Liu, S., Bekker-Jensen, Simon Holst, Mailand, Niels, Lukas, Claudia, Bartek, J. & Lukas, Jiri, 2006, In: Molecular and Cellular Biology. 26, 16, p. 6056-64 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Destruction of Claspin by SCFbetaTrCP restrains Chk1 activation and facilitates recovery from genotoxic stress

    Mailand, Niels, Bekker-Jensen, Simon Holst, Bartek, J. & Lukas, Jiri, 2006, In: Molecular Cell. 23, 3, p. 307-18 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. The replication kinase Cdc7-Dbf4 promotes the interaction of the p150 subunit of chromatin assembly factor 1 with proliferating cell nuclear antigen

    Gérard, A., Koundrioukoff, S., Ramillon, V., Sergère, J., Mailand, Niels, Quivy, J. & Almouzni, G., 2006, In: E M B O Reports. 7, 8, p. 817-23 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. 2005
  14. CDKs promote DNA replication origin licensing in human cells by protecting Cdc6 from APC/C-dependent proteolysis

    Mailand, Niels & Diffley, J. F. X., 23 Sep 2005, In: Cell. 122, 6, p. 915-26 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. 2004
  16. Centrosome-associated Chk1 prevents premature activation of cyclin-B-Cdk1 kinase

    Krämer, A., Mailand, Niels, Lukas, Claudia, Syljuåsen, R. G., Wilkinson, C. J., Nigg, E. A., Bartek, J. & Lukas, Jiri, Sep 2004, In: Nature Cell Biology. 6, 9, p. 884-91 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. 2002
  18. Deregulated human Cdc14A phosphatase disrupts centrosome separation and chromosome segregation

    Mailand, Niels, Lukas, Claudia, Kaiser, B. K., Jackson, P. K., Bartek, J. & Lukas, Jiri, Apr 2002, In: Nature Cell Biology. 4, 4, p. 317-22 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Regulation of G(2)/M events by Cdc25A through phosphorylation-dependent modulation of its stability.

    Mailand, Niels, Podtelejnikov, A. V., Groth, Anja, Mann, M., Bartek, J. & Lukas, Jiri, 2002, In: EMBO Journal. 21, 21, p. 5911-20 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. 2001
  21. DNA damage-activated kinase Chk2 is independent of proliferation or differentiation yet correlates with tissue biology

    Lukas, Claudia, Bartkova, J., Latella, L., Falck, J., Mailand, Niels, Schroeder, T., Sehested, M., Lukas, Jiri & Bartek, J., 1 Jul 2001, In: Cancer Research. 61, 13, p. 4990-3 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis

    Falck, J., Mailand, Niels, Syljuåsen, R. G., Bartek, J. & Lukas, Jiri, 12 Apr 2001, In: Nature. 410, 6830, p. 842-7 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. 2000
  24. Rapid destruction of human Cdc25A in response to DNA damage

    Mailand, Niels, Falck, J., Lukas, Claudia, Syljuåsen, R. G., Welcker, M., Bartek, J. & Lukas, Jiri, 26 May 2000, In: Science (New York, N.Y.). 288, 5470, p. 1425-9 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Involvement of Myc activity in a G(1)/S-promoting mechanism parallel to the pRb/E2F pathway

    Santoni Rugiu, Eric, Falck, J., Mailand, Niels, Bartek, J. & Lukas, Jiri, May 2000, In: Molecular and Cellular Biology. 20, 10, p. 3497-509 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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