Niels Mailand

Niels Mailand

Professor, head of research, Professor


  1. Published

    A DNA helicase remodeling proteins: How DNA-protein crosslink repair unfolds via FANCJ

    Mailand, Niels, 2023, In: Molecular Cell. 83, 1, p. 3-5 3 p.

    Research output: Contribution to journalComment/debatepeer-review

  2. Published

    A new cellular stress response that triggers centriolar satellite reorganization and ciliogenesis

    Villumsen, B. H., Danielsen, J. R., Povlsen, L., Sylvestersen, K. B., Merdes, A., Beli, P., Yang, Y., Choudhary, Chunaram, Nielsen, Michael Lund, Mailand, Niels & Bekker-Jensen, Simon Holst, 11 Oct 2013, In: E M B O Journal. 32, 23, p. 3029-3040

    Research output: Contribution to journalJournal articlepeer-review

  3. Published

    A new non-catalytic role for ubiquitin ligase RNF8 in unfolding higher-order chromatin structure

    Luijsterburg, M. S., Acs, K., Ackermann, L., Wiegant, W. W., Bekker-Jensen, Simon Holst, Larsen, D. H., Khanna, K. K., van Attikum, H., Mailand, Niels & Dantuma, N. P., 2012, In: E M B O Journal. 31, 11, p. 2511-27 17 p.

    Research output: Contribution to journalJournal articlepeer-review

  4. Published

    ATR Prohibits Replication Catastrophe by Preventing Global Exhaustion of RPA

    Toledo Lazaro, L. I., Altmeyer, M., Rask, M., Lukas, Claudia, Larsen, D. H., Povlsen, L. K., Bekker-Jensen, Simon Holst, Mailand, Niels, Bartek, J. & Lukas, Jiri, 21 Nov 2013, In: Cell. 155, 5, p. 1088-1103 16 p.

    Research output: Contribution to journalJournal articlepeer-review

  5. Published

    ATR-Chk1-APC/C-dependent stabilization of Cdc7-ASK (Dbf4) kinase is required for DNA lesion bypass under replication stress

    Yamada, M., Watanabe, K., Mistrik, M., Vesela, E., Protivankova, I., Mailand, Niels, Lee, M. H., Masai, H., Lukas, Jiri & Bartek, J., 15 Nov 2013, In: Genes & Development. 27, 22, p. 2459-2472 14 p.

    Research output: Contribution to journalJournal articlepeer-review

  6. Published

    ATXN3 controls DNA replication and transcription by regulating chromatin structure

    Hernández-Carralero, E., Cabrera, E., Rodríguez-Torres, G., Hernández-Reyes, Y., Singh, A. N., Santa-María, C., Fernández-Justel, J. M., Janssens, R. C., Marteijn, J. A., Evert, B. O., Mailand, Niels, Gómez, M., Ramadan, K., Smits, V. A. J. & Freire, R., 2023, In: Nucleic Acids Research. 51, 11, p. 5396–5413

    Research output: Contribution to journalJournal articlepeer-review

  7. Published

    Activation of the ATR kinase by the RPA-binding protein ETAA1

    Haahr, Peter Thorlund, Hoffmann, Saskia, Tollenaere, M. A. X., Ho, T., Toledo Lazaro, L. I., Mann, Matthias, Bekker-Jensen, Simon Holst, Räschle, M. & Mailand, Niels, Nov 2016, In: Nature Cell Biology. 18, 11, p. 1196–1207

    Research output: Contribution to journalJournal articlepeer-review

  8. Published

    Ago2 facilitates Rad51 recruitment and DNA double-strand break repair by homologous recombination

    Gao, M., Wei, W., Li, M. H., Wu, Y., Ba, Z., Jin, K., Li, M., Liao, Y., Adhikari, S., Chong, Z., Zhang, T., Guo, C., Tang, T., Zhu, B., Xu, X., Mailand, Niels, Yang, Y., Qi, Y. & Danielsen, J. M. R., May 2014, In: Cell Research. 24, 5, p. 532-41 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  9. Published

    An unorthodox partnership in DNA repair pathway choice

    Typas, D. & Mailand, Niels, 2019, In: EMBO Reports. 20, 11, e49105.

    Research output: Contribution to journalEditorialpeer-review

  10. Published

    Assembly and function of DNA double-strand break repair foci in mammalian cells

    Bekker-Jensen, Simon Holst & Mailand, Niels, 10 Dec 2010, In: D N A Repair. 9, 12, p. 1219-28 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  11. CDKs promote DNA replication origin licensing in human cells by protecting Cdc6 from APC/C-dependent proteolysis

    Mailand, Niels & Diffley, J. F. X., 23 Sep 2005, In: Cell. 122, 6, p. 915-26 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  12. Published

    Centriolar satellites: key mediators of centrosome functions

    Tollenaere, M. A. X., Mailand, Niels & Bekker-Jensen, Simon Holst, Jan 2015, In: Cellular and molecular life sciences : CMLS. 73, 1, p. 11-23 13 p.

    Research output: Contribution to journalReviewpeer-review

  13. Centrosome-associated Chk1 prevents premature activation of cyclin-B-Cdk1 kinase

    Krämer, A., Mailand, Niels, Lukas, Claudia, Syljuåsen, R. G., Wilkinson, C. J., Nigg, E. A., Bartek, J. & Lukas, Jiri, Sep 2004, In: Nature Cell Biology. 6, 9, p. 884-91 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  14. Published

    Chemogenetic profiling reveals PP2A-independent cytotoxicity of proposed PP2A activators iHAP1 and DT-061

    Vit, G., Duro, Joana Maria, Rajendraprasad, G., Hertz, Emil Peter Thrane, Holland, L. K. K., Weisser, Melanie, McEwan, B. C., Lopez-Mendez, B., Sotelo-Parrilla, P., Jeyaprakash, A. A., Montoya, Guillermo, Mailand, Niels, Maeda, K., Kettenbach, A., Barisic, Marin & Nilsson, Jakob, 2022, In: EMBO Journal. 41, 14, e110611.

    Research output: Contribution to journalJournal articlepeer-review

  15. Claspin operates downstream of TopBP1 to direct ATR signaling towards Chk1 activation

    Liu, S., Bekker-Jensen, Simon Holst, Mailand, Niels, Lukas, Claudia, Bartek, J. & Lukas, Jiri, 2006, In: Molecular and Cellular Biology. 26, 16, p. 6056-64 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  16. Published

    DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity

    Gupta, R., Somyajit, K., Narita, Takeo, Maskey, E., Stanlie, A., Kremer, M., Typas, D., Lammers, M., Mailand, Niels, Nussenzweig, A., Lukas, Jiri & Choudhary, Chunaram, 2018, In: Cell. 173, 4, p. 972-988

    Research output: Contribution to journalJournal articlepeer-review

  17. DNA damage-activated kinase Chk2 is independent of proliferation or differentiation yet correlates with tissue biology

    Lukas, Claudia, Bartkova, J., Latella, L., Falck, J., Mailand, Niels, Schroeder, T., Sehested, M., Lukas, Jiri & Bartek, J., 1 Jul 2001, In: Cancer Research. 61, 13, p. 4990-3 4 p.

    Research output: Contribution to journalJournal articlepeer-review

  18. Published

    DNA damage-inducible SUMOylation of HERC2 promotes RNF8 binding via a novel SUMO-binding Zinc finger

    Danielsen, J. M. R., Povlsen, L. K., Villumsen, B. H., Streicher, W., Nilsson, Jakob, Wikström, M., Bekker-Jensen, Simon Holst & Mailand, Niels, 2012, In: Journal of Cell Biology. 197, 2, p. 179-87 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  19. Published

    DVC1 (C1orf124) is a DNA damage-targeting p97 adaptor that promotes ubiquitin-dependent responses to replication blocks

    Mosbech, A., Gibbs-Seymour, I., Kagias, K., Thorslund, T., Beli, P., Povlsen, L., Nielsen, S. V., Smedegaard, S., Sedgwick, G., Lukas, Claudia, Hartmann-Petersen, Rasmus, Lukas, Jiri, Choudhary, Chunaram, Pocock, R. D. J., Bekker-Jensen, Simon Holst & Mailand, Niels, 2012, In: Nature Structural and Molecular Biology. 19, 11, p. 1084-92 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  20. Deregulated human Cdc14A phosphatase disrupts centrosome separation and chromosome segregation

    Mailand, Niels, Lukas, Claudia, Kaiser, B. K., Jackson, P. K., Bartek, J. & Lukas, Jiri, Apr 2002, In: Nature Cell Biology. 4, 4, p. 317-22 6 p.

    Research output: Contribution to journalJournal articlepeer-review

  21. Destruction of Claspin by SCFbetaTrCP restrains Chk1 activation and facilitates recovery from genotoxic stress

    Mailand, Niels, Bekker-Jensen, Simon Holst, Bartek, J. & Lukas, Jiri, 2006, In: Molecular Cell. 23, 3, p. 307-18 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  22. Published

    Disease-causing mutations in the XIAP BIR2 domain impair NOD2-dependent immune signalling

    Damgaard, R. B., Fiil, Berthe Katrine, Speckmann, C., Yabal, M., Stadt, U. Z., Bekker-Jensen, Simon Holst, Jost, P. J., Ehl, S., Mailand, Niels & Gyrd-Hansen, Mads, 1 Jul 2013, In: E M B O Journal. 5, p. 1278-1295 18 p.

    Research output: Contribution to journalJournal articlepeer-review

  23. Published

    FAM111 protease activity undermines cellular fitness and is amplified by gain-of-function mutations in human disease

    Hoffmann, Saskia, Pentakota, S., Mund, Andreas, Haahr, Peter Thorlund, Coscia, F., Gallo, M., Mann, Matthias, Taylor, Nicholas M I & Mailand, Niels, 2020, In: EMBO Reports. 21, 10, 14 p., e50662.

    Research output: Contribution to journalJournal articlepeer-review

  24. Published

    GIGYF1/2-Driven Cooperation between ZNF598 and TTP in Posttranscriptional Regulation of Inflammatory Signaling

    Tollenaere, M. A. X., Tiedje, C., Rasmussen, S., Nielsen, J. C., Vind, Anna Constance, Blasius, Melanie, Batth, Tanveer Singh, Mailand, Niels, Olsen, Jesper Velgaard, Gaestel, M. & Bekker-Jensen, Simon Holst, 2019, In: Cell Reports. 26, 13, p. 3511-3521.e4 16 p.

    Research output: Contribution to journalJournal articlepeer-review

  25. Published

    H4K20me0 marks post-replicative chromatin and recruits the TONSL–MMS22L DNA repair complex

    Saredi, G., Huang, H., Hammond, Colin, Alabert, C., Bekker-Jensen, Simon Holst, Forne, I., Reveron-Gomez, Nazaret, Foster, B. M., Mlejnkova, L., Bartke, T., Cejka, P., Mailand, Niels, Imhof, A., Patel, D. J. & Groth, Anja, 30 Jun 2016, In: Nature. 534, 7609, p. 714-8 5 p.

    Research output: Contribution to journalJournal articlepeer-review

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ID: 13844358