Niels Mailand
Professor, head of research, Professor
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The deubiquitylating enzyme USP44 counteracts the DNA double-strand break response mediated by the RNF8 and RNF168 ubiquitin ligases
Mosbech, A., Lukas, Claudia, Bekker-Jensen, Simon Holst & Mailand, Niels, 24 Apr 2013, In: Journal of Biological Chemistry. 288, p. 16579-16587 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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DVC1 (C1orf124) is a DNA damage-targeting p97 adaptor that promotes ubiquitin-dependent responses to replication blocks
Mosbech, A., Gibbs-Seymour, I., Kagias, K., Thorslund, T., Beli, P., Povlsen, L., Nielsen, S. V., Smedegaard, S., Sedgwick, G., Lukas, Claudia, Hartmann-Petersen, Rasmus, Lukas, Jiri, Choudhary, Chunaram, Pocock, R. D. J., Bekker-Jensen, Simon Holst & Mailand, Niels, 2012, In: Nature Structural and Molecular Biology. 19, 11, p. 1084-92 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Proteome dynamics at broken replication forks reveal a distinct ATM-directed repair response suppressing DNA double-strand break ubiquitination
Nakamura, K., Kustatscher, G., Alabert, C., Hödl, M., Forne, I., Völker-Albert, M., Satpathy, S., Beyer, T. E., Mailand, Niels, Choudhary, Chunaram, Imhof, A., Rappsilber, J. & Groth, Anja, 2021, In: Molecular Cell. 81, 3, 23 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Ubiquitin-like protein UBL5 promotes the functional integrity of the Fanconi anemia pathway
Oka, Y., Bekker-Jensen, Simon Holst & Mailand, Niels, 9 Apr 2015, In: E M B O Journal. 34, p. 1385-1398Research output: Contribution to journal › Journal article › Research › peer-review
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UBL5 is essential for pre-mRNA splicing and sister chromatid cohesion in human cells
Oka, Y., Varmark, H., Vitting-Seerup, K., Beli, P., Waage, J. E., Hakobyan, A., Mistrik, M., Choudhary, Chunaram, Rohde, M., Bekker-Jensen, Simon Holst & Mailand, Niels, 2014, In: E M B O Reports. 15, 9, p. 956-964 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Human RNF169 is a negative regulator of the ubiquitin-dependent response to DNA double-strand breaks
Poulsen, M., Lukas, C., Lukas, J., Bekker-Jensen, Simon Holst & Mailand, Niels, 2012, In: Journal of Cell Biology. 197, 2, p. 189-99 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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RNF111/Arkadia is a SUMO-targeted ubiquitin ligase that facilitates the DNA damage response
Poulsen, S. L., Hansen, R. K., Wagner, S. A., van Cuijk, L., van Belle, G. J., Streicher, W., Wikström, M., Choudhary, Chunaram, Houtsmuller, A. B., Marteijn, J. A., Bekker-Jensen, Simon Holst & Mailand, Niels, 10 Jun 2013, In: Journal of Cell Biology. 201, 6, p. 797-807 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass
Povlsen, L. K., Beli, P., Wagner, S. A., Poulsen, S. L., Sylvestersen, K. B., Poulsen, J. W., Nielsen, Michael Lund, Bekker-Jensen, Simon Holst, Mailand, Niels & Choudhary, Chunaram, Oct 2012, In: Nature Cell Biology. 14, 10, p. 1089-98 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Structural Basis of BRCC36 Function in DNA Repair and Immune Regulation
Rabl, J., Bunker, R. D., Schenk, A. D., Cavadini, S., Gill, M. E., Abdulrahman, W., Andrés-Pons, A., Luijsterburg, M. S., Ibrahim, A. F. M., Branigan, E., Aguirre, J. D., Marceau, A. H., Guérillon, C., Bouwmeester, T., Hassiepen, U., Peters, A. H. F. M., Renatus, M., Gelman, L., Rubin, S. M., Mailand, N. & 3 others, , 2019, In: Molecular Cell. 75, 3, p. 483-497.e9 25 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Proteomics reveals dynamic assembly of repair complexes during bypass of DNA cross-links
Räschle, M., Smeenk, G., Hansen, R. K., Temu, T., Oka, Y., Hein, M. Y., Nagaraj, N., Long, D. T., Walter, J. C., Hofmann, K., Storchova, Z., Cox, J., Bekker-Jensen, Simon Holst, Mailand, Niels & Mann, Matthias, 2015, In: Science. 348, 6234, p. 539- 10 p., 1253671.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 13844358
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1999
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Activation of the ATR kinase by the RPA-binding protein ETAA1
Research output: Contribution to journal › Journal article › Research › peer-review
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1718
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Molecular basis and regulation of OTULIN-LUBAC interaction
Research output: Contribution to journal › Journal article › Research › peer-review
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895
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Histone H1 couples initiation and amplification of ubiquitin signalling after DNA damage
Research output: Contribution to journal › Letter › Research › peer-review
Published