Niels Mailand

Niels Mailand

Professor, head of research, Professor

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    ORCID: 0000-0002-6623-709X

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    1. RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins

      Mailand, Niels, Bekker-Jensen, Simon Holst, Faustrup, H., Melander, F., Bartek, J., Lukas, Claudia & Lukas, Jiri, 2007, In: Cell. 131, 5, p. 887-900 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    2. Published

      A DNA helicase remodeling proteins: How DNA-protein crosslink repair unfolds via FANCJ

      Mailand, Niels, 2023, In: Molecular Cell. 83, 1, p. 3-5 3 p.

      Research output: Contribution to journal › Comment/debate › Research › peer-review

    3. Regulation of G(2)/M events by Cdc25A through phosphorylation-dependent modulation of its stability.

      Mailand, Niels, Podtelejnikov, A. V., Groth, Anja, Mann, M., Bartek, J. & Lukas, Jiri, 2002, In: EMBO Journal. 21, 21, p. 5911-20 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Rapid destruction of human Cdc25A in response to DNA damage

      Mailand, Niels, Falck, J., Lukas, Claudia, Syljuåsen, R. G., Welcker, M., Bartek, J. & Lukas, Jiri, 26 May 2000, In: Science (New York, N.Y.). 288, 5470, p. 1425-9 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Nucleotide excision repair-induced H2A ubiquitination is dependent on MDC1 and RNF8 and reveals a universal DNA damage response

      Marteijn, J. A., Bekker-Jensen, Simon Holst, Mailand, Niels, Lans, H., Schwertman, P., Gourdin, A. M., Dantuma, N. P., Lukas, Jiri & Vermeulen, W., 2009, In: Journal of Cell Biology. 186, 6, p. 835-47 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      The ubiquitin-selective segregase VCP/p97 orchestrates the response to DNA double-strand breaks

      Meerang, M., Ritz, D., Paliwal, S., Garajova, Z., Bosshard, M., Mailand, Niels, Janscak, P., Hübscher, U., Meyer, H. & Ramadan, K., 2011, In: Nature Cell Biology. 13, 11, p. 1376-82 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Phosphorylation of SDT repeats in the MDC1 N terminus triggers retention of NBS1 at the DNA damage-modified chromatin

      Melander, F., Bekker-Jensen, Simon Holst, Falck, J., Bartek, J., Mailand, Niels & Lukas, Jiri, 21 Apr 2008, In: Journal of Cell Biology. 181, 2, p. 213-26 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      Ubiquitylation at Stressed Replication Forks: Mechanisms and Functions

      Mirsanaye, Ann Schirin, Typas, D. & Mailand, Niels, 2021, In: Trends in Cell Biology. 31, 7, p. 584-597

      Research output: Contribution to journal › Review › Research › peer-review

    9. Published

      VCF1 is a p97/VCP cofactor promoting recognition of ubiquitylated p97-UFD1-NPL4 substrates

      Mirsanaye, Ann Schirin, Hoffmann, Saskia, Weisser, Melanie, Mund, Andreas, Lopez Mendez, B., Typas, D., van den Boom, J., Benedict, Bente, Hendriks, Ivo Alexander, Nielsen, Michael Lund, Meyer, H., Duxin, Julien, Montoya, Guillermo & Mailand, Niels, 2024, In: Nature Communications. 15, 1, 16 p., 2459.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      The deubiquitylating enzyme USP44 counteracts the DNA double-strand break response mediated by the RNF8 and RNF168 ubiquitin ligases

      Mosbech, A., Lukas, Claudia, Bekker-Jensen, Simon Holst & Mailand, Niels, 24 Apr 2013, In: Journal of Biological Chemistry. 288, p. 16579-16587 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

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