Nadezhda Tsankova Doncheva

Nadezhda Tsankova Doncheva

Assistant Professor

Member of:


    1. 2024
    2. E-pub ahead of print

      A quantitative and site-specific atlas of the citrullinome reveals widespread existence of citrullination and insights into PADI4 substrates

      Stripp, Alexandra, Hendriks, Ivo Alexander, Elsborg, Jonas Damgaard, Buch-Larsen, Sara Charlotte, Nielsen, C. H., Terslev, L., Kirsch, Rebecca, Damgaard, D., Doncheva, Nadezhda Tsankova, Lennartsson, Caroline Linnea Elin, Rykær, M., Jensen, Lars Juhl, Christophorou, M. A. & Nielsen, Michael Lund, 2024, (E-pub ahead of print) In: Nature Structural and Molecular Biology.

      Research output: Contribution to journalJournal articlepeer-review

    3. 2023
    4. Published

      Alteration of microglial metabolism and inflammatory profile contributes to neurotoxicity in a hiPSC-derived microglia model of frontotemporal dementia 3

      Haukedal, H., Syshøj Lorenzen, S., Westi, Emil Winther, Corsi, G., Gadekar, V. P., McQuade, A., Davtyan, H., Doncheva, Nadezhda Tsankova, Schmid, B., Chandrasekaran, Abinaya, Seemann, Ernst Stefan, Cirera, Susanna, Blurton-Jones, M., Meyer, M., Gorodkin, Jan, Aldana, Blanca & Freude, Kristine, 2023, In: Brain, Behavior, and Immunity. 113, p. 353-373

      Research output: Contribution to journalJournal articlepeer-review

    5. Published

      Arena3Dweb: interactive 3D visualization of multilayered networks supporting multiple directional information channels, clustering analysis and application integration

      Kokoli, M., Karatzas, E., Baltoumas, F. A., Schneider, R., Pafilis, E., Paragkamian, S., Doncheva, Nadezhda Tsankova, Jensen, Lars Juhl & Pavlopoulos, G. A., 2023, In: NAR Genomics and Bioinformatics. 5, 2, 8 p., lqad053.

      Research output: Contribution to journalJournal articlepeer-review

    6. Published

      Cross-species high-resolution transcriptome profiling suggests biomarkers and therapeutic targets for ulcerative colitis

      Yarani, R., Palasca, Oana, Doncheva, Nadezhda Tsankova, Anthon, Christian, Pilecki, B., Svane, C. A. S., Mirza, A. H., Litman, Thomas, Holmskov, U., Bang-Berthelsen, C. H., Vilien, M., Jensen, Lars Juhl, Gorodkin, Jan & Pociot, Flemming, 2023, In: Frontiers in Molecular Biosciences. 9, 1081176.

      Research output: Contribution to journalJournal articlepeer-review

    7. Published

      Golgi fragmentation: One of the earliest organelle phenotypes in Alzheimer's disease neurons

      Haukedal, H., Corsi, G. I., Gadekar, V. P., Doncheva, N. T., Kedia, S., de Haan, N., Chandrasekaran, A., Jensen, P., Schiønning, P., Vallin, S., Marlet, F. R., Poon, A., Pires, C., Agha, F. K., Wandall, H. H., Cirera, S., Simonsen, A. H., Nielsen, T. T., Nielsen, J. E., Hyttel, P. & 7 others, Muddashetty, R., Aldana, Blanca, Gorodkin, Jan, Nair, D., Meyer, M., Larsen, M. R. & Freude, Kristine, 2023, In: Frontiers in Neuroscience. 17, 17 p., 1120086.

      Research output: Contribution to journalJournal articlepeer-review

    8. Published

      The STRING database in 2023: protein-protein association networks and functional enrichment analyses for any sequenced genome of interest

      Szklarczyk, D., Kirsch, Rebecca, Koutrouli, Mikaela, Nastou, Katerina, Mehryary, F., Hachilif, R., Gable, A. L., Fang, T., Doncheva, Nadezhda Tsankova, Pyysalo, S., Bork, P., Jensen, Lars Juhl & von Mering, C., 2023, In: Nucleic Acids Research. 51, D1, p. D638-D646 9 p.

      Research output: Contribution to journalJournal articlepeer-review

    9. Published

      The transcriptomic landscape of neurons carrying PSEN1 mutations reveals changes in extracellular matrix components and non-coding gene expression

      Corsi, G. I., Gadekar, V. P., Haukedal, H., Doncheva, Nadezhda Tsankova, Anthon, Christian, Ambardar, S., Palakodeti, D., Hyttel, P., Freude, Kristine, Seemann, Ernst Stefan & Gorodkin, Jan, 2023, In: Neurobiology of Disease. 178, 17 p., 105980.

      Research output: Contribution to journalJournal articlepeer-review

    10. 2022
    11. Published

      Cytoscape stringApp 2.0: Analysis and Visualization of Heterogeneous Biological Networks

      Doncheva, Nadezhda Tsankova, Morris, J. H., Holze, H., Kirsch, Rebecca, Nastou, Katerina, Cuesta-Astroz, Y., Rattei, T., Szklarczyk, D., Von Mering, C. & Jensen, Lars Juhl, 2022, In: Journal of Proteome Research. 22, 2, p. 637-646

      Research output: Contribution to journalJournal articlepeer-review

    12. Published

      Differentially Expressed miRNAs in Ulcerative Colitis and Crohn's Disease

      Yarani, R., Shojaeian, A., Palasca, Oana, Doncheva, Nadezhda Tsankova, Jensen, Lars Juhl, Gorodkin, Jan & Pociot, Flemming, 2022, In: Frontiers in Immunology. 13, 21 p., 865777.

      Research output: Contribution to journalReviewpeer-review

    13. Published

      The impact of PrsA over-expression on the Bacillus subtilis transcriptome during fed-batch fermentation of alpha-amylase production

      Geissler, Adrian Sven, Poulsen, L. D., Doncheva, Nadezhda Tsankova, Anthon, Christian, Seemann, Ernst Stefan, González-Tortuero, E., Breüner, A., Jensen, Lars Juhl, Hjort, C., Vinther, Jeppe & Gorodkin, Jan, 2022, In: Frontiers in Microbiology. 13, 17 p., 909493.

      Research output: Contribution to journalJournal articlepeer-review

    14. 2021
    15. Published

      Astrocytic reactivity triggered by defective autophagy and metabolic failure causes neurotoxicity in frontotemporal dementia type 3

      Chandrasekaran, A., Dittlau, K. S., Corsi, G. I., Haukedal, H., Doncheva, N. T., Ramakrishna, S., Ambardar, S., Salcedo, C., Schmidt, S. I., Zhang, Y., Cirera, S., Pihl, M., Schmid, B., Nielsen, T. T., Nielsen, J. E., Kolko, M., Kobolák, J., Dinnyés, A., Hyttel, P., Palakodeti, D. & 5 others, Gorodkin, Jan, Muddashetty, R. S., Meyer, M., Aldana, Blanca & Freude, Kristine, 2021, In: Stem Cell Reports. 16, 11, p. 2736-2751

      Research output: Contribution to journalJournal articlepeer-review

    16. Published

      Epistatic interactions promote persistence of NS3-Q80K in HCV infection by compensating for protein folding instability

      Dultz, G., Srikakulam, S. K., Konetschnik, M., Shimakami, T., Doncheva, Nadezhda Tsankova, Dietz, J., Sarrazin, C., Biondi, R. M., Zeuzem, S., Tampe, R., Kalinina, O. & Welsch, C., 2021, In: Journal of Biological Chemistry. 297, 3, 12 p., 101031.

      Research output: Contribution to journalJournal articlepeer-review

    17. Published

      Human pathways in animal models: possibilities and limitations

      Doncheva, Nadezhda Tsankova, Palasca, Oana, Yarani, R., Litman, Thomas, Anthon, Christian, Groenen, M. A. M., Stadler, P. F., Pociot, Flemming, Jensen, Lars Juhl & Gorodkin, Jan, 2021, In: Nucleic Acids Research. 49, 4, p. 1859-1871 13 p.

      Research output: Contribution to journalJournal articlepeer-review

    18. Published

      The STRING database in 2021: customizable protein-protein networks, and functional characterization of user-uploaded gene/measurement sets

      Szklarczyk, D., Gable, A. L., Nastou, Katerina, Lyon, D., Kirsch, Rebecca, Pyysalo, S., Doncheva, Nadezhda Tsankova, Legeay, M., Fang, T., Bork, P., Jensen, Lars Juhl & von Mering, C., 2021, In: Nucleic Acids Symposium Series. 49, D1, p. D605-D612 8 p.

      Research output: Contribution to journalJournal articlepeer-review

    19. 2020
    20. Published

      Mutation in FTD3 CHMP2B causes impaired autography and distorted energy metabolism cumulating in reactive astrocyte phenotypes

      Chandrasekaran, A., Dittlau, K. S., Corsi, G., Haukedal, H., Doncheva, N. T., Ramakrishna, S., Ambardar, S., Salcedo, C., Schmidt, S. I., Cirera, S., Pihl, M., Schmid, B., Nielsen, T. T., Nielsen, J., Kolko, M., Kobolak, J., Dinnyes, A., Hyttel, P., Palakodeti, D., Gorodkin, J. & 4 others, Muddashetty, R., Meyer, M., Aldana, Blanca & Freude, Kristine, 2020.

      Research output: Contribution to conferenceConference abstract for conferenceResearch

    21. Published

      Mutations in FTD3 CHMP2B causes impaired autophagy and distorted energy metabolism cumulating in reactive astrocyte phenotypes

      Chandrasekaran, A., Dittlau, K. S., Corsi, G., Doncheva, N. T., Haukedal, H., Ramakrishna, S., Ambardar, S., Salcedo, C., Schmidt, S. I., Cirera, S., Pihl, M., Schmid, B., Nielsen, T. T., Nielsen, J., Kolko, M., Kobolak, J., Dinnyes, A., Hyttel, P., Palakodeti, D., Gorodkin, J. & 4 others, Muddashetty, R., Meyer, M., Aldana, Blanca & Freude, Kristine, 2020.

      Research output: Contribution to conferencePosterResearch

    22. Published

      Non-active site mutants of HIV-1 protease influence resistance and sensitisation towards protease inhibitors

      Bastys, T., Gapsys, V., Walter, H., Heger, E., Doncheva, Nadezhda Tsankova, Kaiser, R., de Groot, B. L. & Kalinina, O., 2020, In: Retrovirology. 17, 1, 14 p., 13.

      Research output: Contribution to journalJournal articlepeer-review

    23. Published

      Proceedings of the EuBIC-MS 2020 Developers’ Meeting

      Ashwood, C., Bittremieux, W., Deutsch, E. W., Doncheva, N. T., Dorfer, V., Gabriels, R., Gorshkov, V., Gupta, S., Jones, A. R., Käll, L., Kopczynski, D., Lane, L., Lautenbacher, L., Legeay, M., Locard-Paulet, M., Mesuere, B., Perez-Riverol, Y., Netz, E., Pfeuffer, J., Sachsenberg, T. & 13 others, Salz, R., Samaras, P., Schiebenhoefer, H., Schmidt, T., Schwämmle, V., Soggiu, A., Uszkoreit, J., Van Den Bossche, T., Van Puyvelde, B., Van Strien, J., Verschaffelt, P., Webel, Henry & Willems, S., 2020, In: EuPA Open Proteomics. 24, p. 1-6 6 p.

      Research output: Contribution to journalEditorial

    24. Published

      Visualize omics data on networks with Omics Visualizer, a Cytoscape App

      Legeay, M., Doncheva, Nadezhda Tsankova, Morris, J. H. & Jensen, Lars Juhl, 2020, In: F1000Research. 9, 15 p.

      Research output: Contribution to journalJournal articlepeer-review

    25. 2019
    26. Published

      Cytoscape stringApp: Network analysis and visualization of proteomics data

      Doncheva, Nadezhda Tsankova, Morris, J., Gorodkin, Jan & Jensen, Lars Juhl, 2019, In: Journal of Proteome Research. 18, 2, p. 623-632

      Research output: Contribution to journalJournal articlepeer-review

    27. Near-Neighbor Interactions in the NS3-4A Protease of HCV Impact Replicative Fitness of Drug-Resistant Viral Variants

      Doncheva, Nadezhda Tsankova, Domingues, F. S., McGivern, D. R., Shimakami, T., Zeuzem, S., Lengauer, T., Lange, C. M., Albrecht, M. & Welsch, C., 2019, In: Journal of Molecular Biology. 431, 12, p. 2354-2368

      Research output: Contribution to journalJournal articlepeer-review

    28. Published

      STRING v11: protein-protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets

      Szklarczyk, D., Gable, A. L., Lyon, D., Junge, A., Wyder, S., Huerta-Cepas, J., Simonovic, M., Doncheva, Nadezhda Tsankova, Morris, J. H., Bork, P., Jensen, Lars Juhl & von Mering, C., 2019, In: Nucleic Acids Research. 47, D1, p. D607-D613 7 p.

      Research output: Contribution to journalJournal articlepeer-review

    29. Published

      Transcriptome landscape of protein-coding genes and long noncoding RNAs in the colon and blood of DSS-induced mouse model of Acute ulcerative colitis

      Yarani, R., Palasca, Oana, Doncheva, Nadezhda Tsankova, Anthon, Christian, Pilecki, B., Litman, Thomas, Holmskov, U., Jensen, Lars Juhl, Gorodkin, Jan & Pociot, Flemming, 2019, In: Journal of Crohn's and Colitis. 13, p. S129-S130

      Research output: Contribution to journalConference abstract in journalpeer-review

    30. 2018
    31. Published

      Consistent Prediction of Mutation Effect on Drug Binding in HIV-1 Protease Using Alchemical Calculations

      Bastys, T., Gapsys, V., Doncheva, Nadezhda Tsankova, Kaiser, R., De Groot, B. L. & Kalinina, O. V., 10 Jul 2018, In: Journal of Chemical Theory and Computation. 14, 7, p. 3397-3408

      Research output: Contribution to journalJournal articlepeer-review

    32. Published

      Viruses.STRING: A Virus-Host Protein-Protein Interaction Database

      Cook, H. V., Doncheva, Nadezhda Tsankova, Szklarczyk, D., von Mering, C. & Jensen, Lars Juhl, 2018, In: Viruses. 10, 10, p. 1-11 519.

      Research output: Contribution to journalJournal articlepeer-review

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