Lars Juhl Jensen

Lars Juhl Jensen

Professor, Group Leader, Professor

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    ORCID: 0000-0001-7885-715X

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    1. Published

      Overview of the Knowledge Management Center for Illuminating the Druggable Genome

      Oprea, T. I., Bologa, C., Holmes, J., Mathias, S., Metzger, V. T., Waller, A., Yang, J. J., Leach, A. R., Jensen, Lars Juhl, Kelleher, K. J., Sheils, T. K., Mathé, E., Avram, S. & Edwards, J. S., 2024, In: Drug Discovery Today. 29, 3, 8 p., 103882.

      Research output: Contribution to journal › Review › Research › peer-review

    2. Published

      Recalibrating Equus evolution using the genome sequence of an early Middle Pleistocene horse

      Orlando, L. A. A., Ginolhac, A., Zhang, G., Froese, D., Albrechtsen, A., Stiller, M., Schubert, M., Cappellini, E., Petersen, B., Moltke, I., Johnson, P. L. F., Fumagalli, M., Mouatt, J. T. V., Raghavan, M., Korneliussen, T. S., Malaspinas, A. S., Vogt, J., Szklarczyk, D. M., Kelstrup, C., Vinther, J. & 36 others, Dolocan, A., Stenderup, Jesper Tandberg, Velazquez, A. M. V., Cahill, J., Rasmussen, M., Wang, X., Min, J., Zazula, G. D., Seguin-Orlando, A., Mortensen, C., Magnussen, K., Thompson, J. F., Weinstock, J., Gregersen, K., Røed, K. H., Eisenmann, V., Rubin, C. J., Miller, D. C., Antczak, D. F., Bertelsen, M. F., Brunak, S., Al-Rasheid, K. A. S., Ryder, O., Andersson, L., Mundy, J., Krogh, Anders, Gilbert, M Thomas P, Kjær, Kurt H., Sicheritz-Pontén, T., Jensen, Lars Juhl, Olsen, Jesper Velgaard, Hofreiter, M., Nielsen, R., Shapiro, B., Wang, J. & Willerslev, Eske, 4 Jul 2013, In: Nature. 499, 7456, p. 74-78 5 p.

      Research output: Contribution to journal › Letter › Research › peer-review

    3. Published

      EXTRACT: interactive extraction of environment metadata and term suggestion for metagenomic sample annotation

      Pafilis, E., Buttigieg, P. L., Ferrell, B., Pereira, E., Schnetzer, J., Arvanitidis, C. & Jensen, Lars Juhl, 2016, In: Database: The Journal of Biological Databases and Curation. 2016, 7 p., baw005.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      The SPECIES and ORGANISMS Resources for Fast and Accurate Identification of Taxonomic Names in Text

      Pafilis, E., Pletscher-Frankild, S., Fanini, L., Faulwetter, S., Pavloudi, C., Vasileiadou, A., Arvanitidis, C. & Jensen, Lars Juhl, 18 Jun 2013, In: PloS one. 8, 6, p. e65390

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      Reflect: augmented browsing for the life scientist

      Pafilis, E., O'Donoghue, S. I., Jensen, Lars Juhl, Horn, H., Kuhn, M., Brown, N. P. & Schneider, R., 2009, In: Nature Biotechnology. 27, 6, p. 508-10 2 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      ENVIRONMENTS and EOL: identification of Environment Ontology terms in text and the annotation of the Encyclopedia of Life

      Pafilis, E., Pletscher-Frankild, S., Schnetzer, J., Fanini, L., Faulwetter, S., Pavloudi, C., Vasileiadou, K., Leary, P., Hammock, J., Schulz, K., Parr, C. S., Arvanitidis, C. & Jensen, Lars Juhl, 2015, In: Bioinformatics. 31, 11, p. 1872-1874

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      TISSUES 2.0: an integrative web resource on mammalian tissue expression

      Palasca, Oana, Santos, A., Stolte, C., Gorodkin, Jan & Jensen, Lars Juhl, 2018, In: Database: The Journal of Biological Databases and Curation. 2018, 1, p. 1-12

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      DistiLD Database: diseases and traits in linkage disequilibrium blocks

      Palleja, A., Horn, H., Eliasson, S. & Jensen, Lars Juhl, 2012, In: Nucleic Acids Research. 40, Database issue, p. D1036-40

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      HOODS: finding context-specific neighborhoods of proteins, chemicals and diseases

      Palleja, A. & Jensen, Lars Juhl, 2015, In: PeerJ. 3, p. 1-10 10 p., e1057.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      Genome-wide identification of clusters of predicted microRNA binding sites as microRNA sponge candidates

      Pan, X., Wenzel, Anne, Jensen, Lars Juhl & Gorodkin, Jan, 2018, In: PLoS ONE. 13, 8, 15 p., e0202369.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      Inferring disease-associated long non-coding RNAs using genome - wide tissue expression profiles

      Pan, X., Jensen, Lars Juhl & Gorodkin, Jan, 2019, In: Bioinformatics. 35, 9, p. 1494-1502 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      WebCircRNA: Classifying the Circular RNA Potential of Coding and Noncoding RNA.

      Pan, X., Xiong, K., Anthon, Christian, Hyttel, P., Freude, Kristine, Jensen, Lars Juhl & Gorodkin, Jan, 6 Nov 2018, In: Genes. 9, 11, 11 p., 536.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      BioStar: an online question & answer resource for the bioinformatics community

      Parnell, L. D., Lindenbaum, P., Shameer, K., Dall'Olio, G. M., Swan, D. C., Jensen, Lars Juhl, Cockell, S. J., Pedersen, B. S., Mangan, M. E., Miller, C. A. & Albert, I., 2011, In: P L o S Computational Biology (Online). 7, 10, p. e1002216

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. A DNA structural atlas for Escherichia coli

      Pedersen, A. G., Jensen, Lars Juhl, Brunak, S., Staerfeldt, H. H. & Ussery, D., 2000, In: Journal of Molecular Biology. 299, 4, p. 907-30 24 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      Impact of microRNA-130a on the neutrophil proteome

      Pedersen, C. C., Refsgaard, J. C., Østergaard, Ole, Jensen, Lars Juhl, Heegaard, N. H. H., Borregaard, N. & Cowland, J. B., 25 Nov 2015, In: B M C Immunology. 16, 10 p., 70.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Assessing systems properties of yeast mitochondria through an interaction map of the organelle

      Perocchi, F., Jensen, Lars Juhl, Gagneur, J., Ahting, U., von Mering, C., Bork, P., Prokisch, H. & Steinmetz, L. M., 2006, In: P L o S Genetics (Online). 2, 10, p. e170

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      Phosphorylation of SHP2 at Tyr62 enables acquired resistance to SHP2 allosteric inhibitors in FLT3-ITD-driven AML

      Pfeiffer, A., Franciosa, Giulia, Locard-Paulet, Marie, Piga, I., Reckzeh, K., Vemulapalli, V., Blacklow, S. C., Theilgaard-Mønch, Kim, Jensen, Lars Juhl & Olsen, Jesper Velgaard, 2022, In: Cancer Research. 82, 11, p. 2141-2155 15 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. Published

      Design, implementation, and operation of a rapid, robust named entity recognition web service

      Pletscher-Frankild, S. & Jensen, Lars Juhl, 2019, In: Journal of Cheminformatics. 11, 6 p., 19.

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Published

      DISEASES: Text mining and data integration of disease-gene associations

      Pletscher-Frankild, S., Pallejà, A., Tsafou, K., Binder, J. X. & Jensen, Lars Juhl, Mar 2015, In: Methods. 74, p. 83-9 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      Comprehensive profiling of proteome changes upon sequential deletion of deubiquitylating enzymes

      Poulsen, J. W., Madsen, C. T., Young, C., Kelstrup, C. D., Grell, H. C., Henriksen, P., Jensen, Lars Juhl & Nielsen, Michael Lund, 2012, In: Journal of Proteomics. 75, 13, p. 3886-97 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      eggNOG v3.0: Orthologous groups covering 1133 organisms at 41 different taxonomic ranges

      Powell, S., Trachana, K., Letunic, I., Doerks, T., Bork, P., Szklarczyk, D., Jensen, Lars Juhl, Roth, A., Von Mering, C., Kuhn, M., Muller, J., Arnold, R. & Rattei, T., 2012, In: Nucleic Acids Research. 40, D1, p. D284-9

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Published

      eggNOG v4.0: nested orthology inference across 3686 organisms

      Powell, S., Forslund, K., Szklarczyk, D. M., Trachana, K., Roth, A., Huerta-Cepas, J., Gabaldón, T., Rattei, T., Creevey, C., Kuhn, M., Jensen, Lars Juhl, von Mering, C. & Bork, P., 1 Dec 2013, In: Nucleic Acids Research. 42, D1, p. D231-D239 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      Toward molecular trait-based ecology through integration of biogeochemical, geographical and metagenomic data

      Raes, J., Letunic, I., Yamada, T., Jensen, Lars Juhl & Bork, P., 2011, In: Molecular Systems Biology. 7, p. 473

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. E-pub ahead of print

      A quantitative and site-specific atlas of the citrullinome reveals widespread existence of citrullination and insights into PADI4 substrates

      Stripp, Alexandra, Hendriks, Ivo Alexander, Elsborg, Jonas Damgaard, Buch-Larsen, Sara Charlotte, Nielsen, C. H., Terslev, L., Kirsch, Rebecca, Damgaard, D., Doncheva, Nadezhda Tsankova, Lennartsson, Caroline Linnea Elin, Rykær, M., Jensen, Lars Juhl, Christophorou, M. A. & Nielsen, Michael Lund, 2024, (E-pub ahead of print) In: Nature Structural and Molecular Biology.

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Published

      Search Databases and Statistics: Pitfalls and Best Practices in Phosphoproteomics

      Refsgaard, J. C., Munk, S. & Jensen, Lars Juhl, 2016, Phospho-Proteomics: Methods and Protocols. Stechow, L. V. (ed.). Springer Publishing Company, Vol. 1355. p. 323-39 17 p. (Methods in molecular biology (Clifton, N.J.)).

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    26. Published

      Hunting for the elusive target antigen in gestational alloimmune liver disease (GALD)

      Rieneck, K., Rasmussen, K. K., Schoof, E. M., Clausen, F. B., Holze, H., Bergholt, Thomas, Jørgensen, M. H., Christensen, Vibeke Brix, Almaas, R., Jordal, P. L., Locard-Paulet, Marie, Runager, K., Nielsen, L. K., Schlotmann, Balthasar Clemens, Weischenfeldt, Joachim Lütken, Jensen, Lars Juhl & Dziegiel, Morten Hanefeld, 2023, In: PLoS ONE. 18, 10, 25 p., e0286432.

      Research output: Contribution to journal › Journal article › Research › peer-review

    27. Published

      Transcriptional regulation is a major controller of cell cycle transition dynamics

      Romanel, A., Jensen, Lars Juhl, Cardelli, L. & Csikász-Nagy, A., 2012, In: P L o S One. 7, 1, p. e29716

      Research output: Contribution to journal › Journal article › Research › peer-review

    28. Published

      Using electronic patient records to discover disease correlations and stratify patient cohorts

      Roque, F. S., Jensen, P. B., Schmock, H., Dalgaard, M., Andreatta, M., Hansen, T., Søeby, K., Bredkjær, S., Juul, Anders, Werge, Thomas, Jensen, Lars Juhl & Brunak, Søren, 2011, In: P L o S Computational Biology. 7, 8, p. e1002141 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    29. Published

      A comparison of protein kinases inhibitor screening methods using both enzymatic activity and binding affinity determination

      Rudolf, A. F., Skovgaard, T., Knapp, S., Jensen, Lars Juhl & Berthelsen, J., 2014, In: PloS one. 9, 6, p. 1-5 6 p., e98800.

      Research output: Contribution to journal › Journal article › Research › peer-review

    30. Published

      miRandola 2017: a curated knowledge base of non-invasive biomarkers

      Russo, F., Di Bella, S., Vannini, F., Berti, G., Scoyni, F., Cook, H. V., Santos, A., Nigita, G., Bonnici, V., Laganà, A., Geraci, F., Pulvirenti, A., Giugno, R., De Masi, F., Belling, K., Jensen, Lars Juhl, Brunak, Søren, Pellegrini, M. & Ferro, A., 1 Jan 2018, In: Nucleic Acids Research. 46, D1, p. D354-D359 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    31. Published

      A knowledge graph to interpret clinical proteomics data

      Santos, A., Colaço, A. R., Nielsen, A. B., Niu, Lili, Strauss, Maximilian, Geyer, P. E., Coscia, F., Albrechtsen, Nicolai Jacob Wewer, Mundt, F., Jensen, Lars Juhl & Mann, Matthias, 2022, In: Nature Biotechnology. 40, p. 692–702

      Research output: Contribution to journal › Journal article › Research › peer-review

    32. Published

      Cyclebase 3.0: a multi-organism database on cell-cycle regulation and phenotypes

      Santos Delgado, A., Wernersson, R. & Jensen, Lars Juhl, Jan 2015, In: Nucleic Acids Research. 43, D1, p. D1140-4 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    33. Published

      Comprehensive comparison of large-scale tissue expression datasets

      Santos Delgado, A., Tsafou, K., Stolte, C., Pletscher-Frankild, S., O'Donoghue, S. I. & Jensen, Lars Juhl, 2015, In: PeerJ. 3, e1054.

      Research output: Contribution to journal › Journal article › Research › peer-review

    34. Large-scale extraction of gene regulation for model organisms in an ontological context

      Saric, J., Jensen, Lars Juhl & Rojas, I., 2005, In: In Silico Biology. 5, 1, p. 21-32 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    35. Extraction of regulatory gene/protein networks from Medline

      Saric, J., Jensen, Lars Juhl, Ouzounova, R., Rojas, I. & Bork, P., 2006, In: Bioinformatics. 22, 6, p. 645-50 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    36. Published

      Microblogging the ISMB: a new approach to conference reporting

      Saunders, N., Beltrão, P., Jurczak, D., Krause, R., Kuhn, M., Wu, S. & Jensen, Lars Juhl, 2009, In: PLoS Computational Biology. 5, 1, p. e1000263

      Research output: Contribution to journal › Journal article › Research › peer-review

    37. Published

      Avoiding abundance bias in the functional annotation of posttranslationally modified proteins

      Schölz, C., Lyon, D., Refsgaard, J. C., Jensen, Lars Juhl, Choudhary, Chunaram & Weinert, B. T., Nov 2015, In: Nature Methods. 12, p. 1003-4 2 p.

      Research output: Contribution to journal › Comment/debate › Research › peer-review

    38. Published

      Acetylation site specificities of lysine deacetylase inhibitors in human cells

      Schölz, C., Weinert, B. T., Wagner, S. A., Beli, P., Miyake, Y., Qi, J., Jensen, Lars Juhl, Streicher, W., McCarthy, A. R., Westwood, N. J., Lain, S., Cox, J., Matthias, P., Mann, M., Bradner, J. E. & Choudhary, Chunaram, 2015, In: Nature Biotechnology. 33, p. 415–423

      Research output: Contribution to journal › Journal article › Research › peer-review

    39. Extraction of transcript diversity from scientific literature

      Shah, P. K., Jensen, Lars Juhl, Boué, S. & Bork, P., 2005, In: P L o S Computational Biology. 1, 1, p. e10

      Research output: Contribution to journal › Journal article › Research › peer-review

    40. Enhanced function annotations for Drosophila serine proteases: a case study for systematic annotation of multi-member gene families

      Shah, P. K., Tripathi, L. P., Jensen, Lars Juhl, Gahnim, M., Mason, C., Furlong, E. E., Rodrigues, V., White, K. P., Bork, P. & Sowdhamini, R., 2008, In: Gene. 407, 1-2, p. 199-215 17 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    41. Published

      TCRD and Pharos 2021: mining the human proteome for disease biology

      Sheils, T. K., Mathias, S. L., Kelleher, K. J., Siramshetty, V. B., Nguyen, D. T., Bologa, C. G., Jensen, Lars Juhl, Vidović, D., Koleti, A., Schürer, S. C., Waller, A., Yang, J. J., Holmes, J., Bocci, G., Southall, N., Dharkar, P., Mathé, E., Simeonov, A. & Oprea, T. I., 2021, In: Nucleic Acids Research. 49, D1, p. D1334-D1346 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    42. Published

      Seqenv: linking sequences to environments through text mining

      Sinclair, L., Ijaz, U. Z., Jensen, Lars Juhl, Coolen, M. J. L., Gubry-Rangin, C., Chroňáková, A., Oulas, A., Pavloudi, C., Schnetzer, J., Weimann, A., Ijaz, A., Eiler, A., Quince, C. & Pafilis, E., 20 Dec 2016, In: PeerJ. 4, p. 1-17 17 p., e2690.

      Research output: Contribution to journal › Journal article › Research › peer-review

    43. Published

      Darkness in the Human Gene and Protein Function Space: Widely Modest or Absent Illumination by the Life Science Literature and the Trend for Fewer Protein Function Discoveries Since 2000

      Sinha, S., Eisenhaber, B., Jensen, Lars Juhl, Kalbuaji, B. & Eisenhaber, F., 2018, In: Proteomics. 18, 21-22, p. 1-13 e1800093.

      Research output: Contribution to journal › Journal article › Research › peer-review

    44. The atlas visualisation of genome-wide information

      Skovgaard, M., Jensen, Lars Juhl, Friis, C., Stærfeldt, H. H., Worning, P., Brunak, S. & Ussery, D. W., 2002, Methods in Microbiology. Vol. 33. p. 49-63

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    45. Published

      On the total number of genes and their length distribution in complete microbial genomes

      Skovgaard, M., Jensen, Lars Juhl, Brunak, Søren, Ussery, D. & Krogh, Anders, 2001, In: Trends in Genetics. 17, 8, p. 425-8 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    46. Martini: using literature keywords to compare gene sets

      Soldatos, T. G., O'Donoghue, S. I., Satagopam, V. P., Jensen, Lars Juhl, Brown, N. P., Barbosa-Silva, A. & Schneider, R., 2010, In: Nucleic Acids Research. 38, 1, p. 26-38 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    47. Published

      Homology-directed repair protects the replicating genome from metabolic assaults

      Somyajit, K., Spies, J., Coscia, F., Kirik, U., Rask, M., Lee, J., Neelsen, K. J., Mund, Andreas, Jensen, Lars Juhl, Paull, T. T., Mann, Matthias & Lukas, Jiri, 2021, In: Developmental Cell. 56, 4, p. 461-477.e7

      Research output: Contribution to journal › Journal article › Research › peer-review

    48. Published

      Proteomic analysis of arginine methylation sites in human cells reveals dynamic regulation during transcriptional arrest

      Sylvestersen, K. B., Horn, H., Jungmichel, S., Jensen, Lars Juhl & Nielsen, Michael Lund, 21 Feb 2014, In: Molecular & Cellular Proteomics. 13, p. 2072-2088 17 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    49. Published

      STRING v10: protein-protein interaction networks, integrated over the tree of life

      Szklarczyk, D., Franceschini, A., Wyder, S., Forslund, K., Heller, D., Huerta-Cepas, J., Simonovic, M., Roth, A., Santos Delgado, A., Tsafou, K. P., Kuhn, M., Bork, P., Jensen, Lars Juhl & von Mering, C., 28 Jan 2015, In: Nucleic Acids Research. 43, D1, p. D447-52 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    50. Published

      Protein-Protein Interaction Databases

      Szklarczyk, D. & Jensen, Lars Juhl, 2015, Protein-Protein Interactions: Methods and Applications. Meyerkord, C. L. & Fu, H. (eds.). 2 ed. New York: Springer Publishing Company, Vol. 1278. p. 39-56 18 p. (Methods in Molecular Biology, Vol. 1278).

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

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