Guillermo Montoya

Guillermo Montoya

Professor, head of research, Professor

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    ORCID: 0000-0002-8269-3941

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    1. 5'-Cytosine-phosphoguanine (CpG) methylation impacts the activity of natural and engineered meganucleases

      Valton, J., Daboussi, F., Leduc, S., Molina, R., Redondo, P., Macmaster, R., Montoya, Guillermo & Duchateau, P., 31 Aug 2012, In: The Journal of Biological Chemistry. 287, 36, p. 30139-50 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    2. Published

      A Consensus Binding Motif for the PP4 Protein Phosphatase

      Ueki, Y., Kruse, Thomas, Weisser, Melanie, Sundell, G. N., Larsen, Marie Sofie Yoo, Mendez, B. L., Jenkins, N. P., Garvanska, Dimitriya Hristoforova, Cressey, L., Zhang, G., Davey, N., Montoya, Guillermo, Ivarsson, Y., Kettenbach, A. N. & Nilsson, Jakob, 2019, In: Molecular Cell. 76, 6, p. 953-964.e6

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Published

      A Conserved Motif Provides Binding Specificity to the PP2A-B56 Phosphatase

      Hertz, Emil Peter Thrane, Kruse, Thomas, Davey, N. E., López-Méndez, B., Sigurdsson, J. O., Montoya, Guillermo, Olsen, Jesper Velgaard & Nilsson, Jakob, 2016, In: Molecular Cell. 63, 4, p. 686-695 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      A PTIP-PA1 subcomplex promotes transcription for IgH class switching independently from the associated MLL3/MLL4 methyltransferase complex

      Starnes, L. M., Su, D., Pikkupeura, L. M., Weinert, B. T., Santos, M. A., Mund, A., Soria, R., Cho, Y-W., Pozdnyakova, I., Kubec Højfeldt, M., Lages Lino Vala, A., Yang, W., López-Méndez, B., Lee, J-E., Peng, W., Yuan, J., Ge, K., Montoya, G., Nussenzweig, A., Choudhary, C. R. & 1 others, Daniel, J. A., 15 Jan 2016, In: Genes & Development. 30, 2, p. 149-163 15 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      A Type III-B Cmr effector complex catalyzes the synthesis of cyclic oligoadenylate second messengers by cooperative substrate binding

      Han, W., Stella, S., Zhang, Y., Guo, T., Sulek, K., Peng-Lundgren, L., Montoya, Guillermo & She, Q., 2018, In: Nucleic Acids Research. 46, 19, p. 10319-10330 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      A highly conserved pocket on PP2A-B56 is required for hSgo1 binding and cohesion protection during mitosis

      Ueki, Y., Hadders, M. A., Weisser, Melanie, Nasa, I., Sotelo-Parrilla, P., Cressey, L. E., Gupta, T., Hertz, Emil Peter Thrane, Kruse, Thomas, Montoya, Guillermo, Jeyaprakash, A. A., Kettenbach, A., Lens, S. M. A. & Nilsson, Jakob, 2021, In: EMBO Reports. 22, 7, 13 p., e52295.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      A novel TPR-BEN domain interaction mediates PICH-BEND3 association

      Pitchai, G. P., Kaulich, M., Bizard, A. H., Mesa, Pablo, Yao, Q., Sarlos, K., Streicher, W. W., Nigg, E. A., Montoya, Guillermo & Hickson, Ian David, 2017, In: Nucleic Acids Research. 19, 2, p. 11413–11424

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      Allosteric regulation of Csx1, a type IIIB-associated CARF domain ribonuclease by RNAs carrying a tetraadenylate tail

      Han, W., Pan, S., López-Méndez, B., Montoya, Guillermo & She, Q., 13 Oct 2017, In: Nucleic Acids Research. 45, 18, p. 10740-10750 11 p., gkx726.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      Assembly of Francisella novicida Cpf1 endonuclease in complex with guide RNA and target DNA

      Alcón, P., Montoya, Guillermo & Stella, S., 1 Jul 2017, In: Acta Crystallographica Section F: Structural Biology Communications. 73, Pt 7, p. 409-415 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      BuD, a helix-loop-helix DNA-binding domain for genome modification

      Stella, S., Molina, R., López-Méndez, B., Juillerat, A., Bertonati, C., Daboussi, F., Campos-Olivas, R., Duchateau, P. & Montoya, Guillermo, 2014, In: Acta Crystallographica Section D: Structural Biology. 70, 7, p. 2042-2052 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      CRISPR-Cas12a: functional overview and applications

      Paul, B. & Montoya, Guillermo, 2020, In: Biomedical Journal. 43, 1, p. 8-17

      Research output: Contribution to journal › Review › Research › peer-review

    12. Published

      Characterization of the NTPR and BD1 interacting domains of the human PICH-BEND3 complex

      Pitchai, G. P., Hickson, Ian David, Streicher, W., Montoya, Guillermo & Mesa, Pablo, Aug 2016, In: Acta Crystallographica. Section F: Structural Biology and Crystallization Communications Online. 72, 8, p. 646-651 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      Chemogenetic profiling reveals PP2A-independent cytotoxicity of proposed PP2A activators iHAP1 and DT-061

      Vit, G., Duro, Joana Maria, Rajendraprasad, G., Hertz, Emil Peter Thrane, Holland, L. K. K., Weisser, Melanie, McEwan, B. C., Lopez-Mendez, B., Sotelo-Parrilla, P., Jeyaprakash, A. A., Montoya, Guillermo, Mailand, Niels, Maeda, K., Kettenbach, A., Barisic, Marin & Nilsson, Jakob, 2022, In: EMBO Journal. 41, 14, e110611.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      Class 2 CRISPR-Cas RNA-guided endonucleases: Swiss Army knives of genome editing

      Stella, S., Alcón, P. & Montoya, Guillermo, Nov 2017, In: Nature Structural and Molecular Biology. 24, 11, p. 882-892 11 p.

      Research output: Contribution to journal › Review › Research › peer-review

    15. Published

      Comprehensive analysis of the specificity of transcription activator-like effector nucleases

      Juillerat, A., Dubois, G., Valton, J., Thomas, S., Stella, S., Maréchal, A., Langevin, S., Benomari, N., Bertonati, C., Silva, G. H., Daboussi, F., Epinat, J., Montoya, Guillermo, Duclert, A. & Duchateau, P., Apr 2014, In: Nucleic Acids Research. 42, 8, p. 5390-402 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      Conformational Activation Promotes CRISPR-Cas12a Catalysis and Resetting of the Endonuclease Activity

      Stella, S., Mesa, Pablo, Thomsen, J., Paul, B., Alcón, P., Jensen, S. B., Saligram, B., Moses, M. E., Hatzakis, Nikos & Montoya, Guillermo, 13 Dec 2018, In: Cell. 175, 7, p. 1856-1871.e21 16 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      Crystal Structure of the Homing Endonuclease I-CvuI Provides a New Template for Genome Modification

      Molina, R., Redondo, P., López-Méndez, B., Villate, M., Merino, N., Blanco, F. J., Valton, J., Grizot, S., Duchateau, P., Prieto, J. & Montoya, Guillermo, 27 Nov 2015, In: The Journal of Biological Chemistry. 290, 48, p. 28727-36 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. Published

      Crystal structure of the open conformation of the mammalian chaperonin CCT in complex with tubulin

      Muñoz, I. G., Yébenes, H., Zhou, M., Mesa, Pablo, Serna, M., Park, A. Y., Bragado-Nilsson, E., Beloso, A., de Cárcer, G., Malumbres, M., Robinson, C. V., Valpuesta, J. M. & Montoya, Guillermo, Jan 2011, In: Nature Structural & Molecular Biology. 18, 1, p. 14-9 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Crystallization and preliminary X-ray diffraction analysis of the homing endonuclease I-CvuI from Chlorella vulgaris in complex with its target DNA

      Redondo, P., Merino, N., Villate, M., Blanco, F. J., Montoya, Guillermo & Molina, R., Feb 2014, In: Acta crystallographica. Section F, Structural biology communications. 70, Pt 2, p. 256-9 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      DAXX adds a de novo H3.3K9me3 deposition pathway to the histone chaperone network

      Carraro, Massimo, Hendriks, Ivo Alexander, Hammond, Colin, Solis-Mezarino, V., Völker-Albert, M., Elsborg, Jonas Damgaard, Weisser, Melanie, Spanos, C., Montoya, Guillermo, Rappsilber, J., Imhof, A., Nielsen, Michael Lund & Groth, Anja, 2023, In: Molecular Cell. 83, 7, p. 1075-1092.e9 28 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      DeepFRET, a software for rapid and automated single-molecule FRET data classification using deep learning

      Thomsen, J., Sletfjerding, M. B., Jensen, S. B., Stella, S., Paul, B., Malle, M. G., Montoya, Guillermo, Petersen, Troels Christian & Hatzakis, Nikos, Nov 2020, In: eLife. 9, 21 p., e60404.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Published

      Direct Observation of CRISPR-Cas12 Conformational Sampling by SM FRET and Cryo EM Reveals how Conformational Activation Promotes Catalysis and Resetting of the Endonuclease Activity

      Stella, S., Mesa, Pablo, Thomsen, J., Paul, B., Alcon, P., Jensen, S. B., Moses, M. E., Montoya, Guillermo & Hatzakis, Nikos, 7 Feb 2020, In: Biophysical Journal. 118, 3, p. 223A-224A 2 p.

      Research output: Contribution to journal › Conference abstract in journal › Research

    23. Directly from the source: endogenous preparations of molecular machines

      Mesa, Pablo, Deniaud, A., Montoya, Guillermo & Schaffitzel, C., Jun 2013, In: Current Opinion in Structural Biology. 23, 3, p. 319-25 7 p.

      Research output: Contribution to journal › Review › Research › peer-review

    24. Published

      Editorial overview: Protein-nucleic acid interactions: 'Takes two to Tango'

      Montoya, Guillermo & Carlomagno, T., 2020, In: Current Opinion in Structural Biology. 65, p. v-vi 2 p.

      Research output: Contribution to journal › Editorial › Research

    25. Published

      Electron Microscopy Structural Insights into CPAP Oligomeric Behavior: A Plausible Assembly Process of a Supramolecular Scaffold of the Centrosome

      Alvarez-Cabrera, A. L., Delgado, S., Gil-Carton, D., Mortuza, G. B., Montoya, Guillermo, Sorzano, C. O. S., Tang, T. K. & Carazo, J. M., 2017, In: Frontiers in Molecular Biosciences. 4, 14 p., 17.

      Research output: Contribution to journal › Journal article › Research › peer-review

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    ID: 93716435