Atul Shahaji Deshmukh

Atul Shahaji Deshmukh

Associate Professor

  • Deshmukh Group

    Blegdamsvej 3B, Mærsk Tårnet, 8. sal

    2200 København N.

    Phone: +4535325313Mobile: +4571466221

  1. 2024
  2. Published

    Exercise-induced crosstalk between immune cells and adipocytes in humans: Role of oncostatin-M

    Dollet, L., Lundell, L. S., Chibalin, A. V., Pendergrast, L. A., Pillon, N. J., Lansbury, Elizabeth Laura, Elmastas, M., Frendo-Cumbo, S., Jalkanen, J., de Castro Barbosa, T., Cervone, D. T., Caidahl, K., Dmytriyeva, O., Deshmukh, Atul Shahaji, Barrès, Romain, Rydén, M., Wallberg-Henriksson, H., Zierath, Juleen R & Krook, A., 2024, In: Cell Reports Medicine. 5, 1, 20 p., 101348.

    Research output: Contribution to journalJournal articlepeer-review

  3. E-pub ahead of print

    Harnessing the power of proteomics in precision diabetes medicine

    Kurgan, Nigel Kilty, Larsen, Jeppe Kjærgaard & Deshmukh, Atul Shahaji, 2024, (E-pub ahead of print) In: Diabetologia.

    Research output: Contribution to journalReviewpeer-review

  4. Published

    Mass spectrometry-based proteomics approaches to interrogate skeletal muscle adaptations to exercise

    Cervone, D. T., Moreno Justicia, Roger, Prats Quesada, Júlia & Deshmukh, Atul Shahaji, 2024, In: Scandinavian Journal of Medicine and Science in Sports. 34, 1, 17 p.

    Research output: Contribution to journalJournal articlepeer-review

  5. Published

    Plasma proteome profiling reveals metabolic and immunologic differences between Anorexia Nervosa subtypes

    Samodova-Sommer, Diana, Hoel, A., Hansen, T. H., Clausen, L., Telléus, G. K., Marti, H. P., Pedersen, Oluf Borbye, Støving, R. K. & Deshmukh, Atul Shahaji, 2024, In: Metabolism: Clinical and Experimental. 152, 11 p., 155760.

    Research output: Contribution to journalJournal articlepeer-review

  6. Published
  7. 2023
  8. Published

    CaMKK2 is not involved in contraction-stimulated AMPK activation and glucose uptake in skeletal muscle

    Negoita, F., Addinsall, A. B., Hellberg, K., Bringas, C. F., Hafen, P. S., Sermersheim, T. J., Agerholm, M., Lewis, C. T. A., Ahwazi, D., Ling, N. X. Y., Larsen, J. K., Deshmukh, A. S., Hossain, M. A., Oakhill, J. S., Ochala, J., Brault, J. J., Sankar, U., Drewry, D. H., Scott, J. W., Witczak, C. A. & 1 others, Sakamoto, Kei, 2023, In: Molecular Metabolism. 75, 14 p., 101761.

    Research output: Contribution to journalJournal articlepeer-review

  9. Published

    High-throughput proteomics uncovers exercise training and type 2 diabetes-induced changes in human white adipose tissue

    Larsen, Jeppe Kjærgaard, Kruse, R., Sahebekhtiari, N., Moreno Justicia, Roger, Jorba, G. G., Petersen, M. H., de Almeida, M. E., Ørtenblad, N., Deshmukh, Atul Shahaji & Højlund, K., 2023, In: Science Advances. 9, 48, 16 p., eadi7548.

    Research output: Contribution to journalJournal articlepeer-review

  10. 2022
  11. Published

    Exercise suppresses tumor growth independent of high fat food intake and associated immune dysfunction

    Hojman, P., Stagaard, Rikke, Adachi-Fernandez, E., Deshmukh, Atul Shahaji, Mund, Andreas, Olsen, C. H., Keller, L., Pedersen, Bente Klarlund & Gehl, Julie, 2022, In: Scientific Reports. 12, 1, 5476.

    Research output: Contribution to journalJournal articlepeer-review

  12. Published

    Exercise timing influences multi-tissue metabolome and skeletal muscle proteome profiles in type 2 diabetic patients - A randomized crossover trial

    Savikj, M., Stocks, Ben Nicholas, Sato, S., Caidahl, K., Krook, A., Deshmukh, Atul Shahaji, Zierath, Juleen R & Wallberg-Henriksson, H., 2022, In: Metabolism. 135, 14 p., 155268.

    Research output: Contribution to journalJournal articlepeer-review

  13. Published

    High-intensity interval training remodels the proteome and acetylome of human skeletal muscle

    Hostrup, Morten, Lemminger, A. K., Stocks, Ben Nicholas, Gonzalez-Franquesa, A., Larsen, Jeppe Kjærgaard, Prats Quesada, Júlia, Thomassen, Martin, Weinert, B. T., Bangsbo, Jens & Deshmukh, Atul Shahaji, 2022, In: eLife. 11, 37 p., 69802.

    Research output: Contribution to journalJournal articlepeer-review

  14. Published

    Illumination of the endogenous insulin-regulated TBC1D4 interactome in human skeletal muscle

    Larsen, Jeppe Kjærgaard, Larsen, Magnus Romme, Birk, Jesper Bratz, Steenberg, D. E., Hingst, J. R., Højlund, K., Chadt, A., Al-Hasani, H., Deshmukh, Atul Shahaji, Wojtaszewski, Jørgen F P & Kjøbsted, Rasmus, 2022, In: Diabetes. 71, 5, p. 906-920

    Research output: Contribution to journalJournal articlepeer-review

  15. Published

    Integrated Liver and Plasma Proteomics in Obese Mice Reveals Complex Metabolic Regulation

    Stocks, Ben Nicholas, Gonzalez-Franquesa, A., Borg, M. L., Björnholm, M., Niu, Lili, Zierath, Juleen R & Deshmukh, Atul Shahaji, 2022, In: Molecular and Cellular Proteomics. 21, 3, 19 p., 100207.

    Research output: Contribution to journalJournal articlepeer-review

  16. Published

    Organ-specific metabolic pathways distinguish prediabetes, type 2 diabetes, and normal tissues

    Diamanti, K., Cavalli, M., Pereira, M. J., Pan, G., Castillejo-López, C., Kumar, C., Mundt Madsen, Filip Oskar, Komorowski, J., Deshmukh, Atul Shahaji, Mann, Matthias, Korsgren, O., Eriksson, J. W. & Wadelius, C., 2022, In: Cell Reports Medicine. 3, 10, 21 p., 100763.

    Research output: Contribution to journalJournal articlepeer-review

  17. Published

    Protocol to characterize mitochondrial supercomplexes from mouse tissues by combining BN-PAGE and MS-based proteomics

    Moreno Justicia, Roger, Gonzalez-Franquesa, A., Stocks, Ben Nicholas & Deshmukh, Atul Shahaji, 2022, In: STAR Protocols. 3, 1, 21 p., 101135.

    Research output: Contribution to journalJournal articlepeer-review

  18. Published

    The proteomic profile of the human myotendinous junction

    Karlsen, Anders, Gonzalez-Franquesa, A., Jakobsen, J. R., Krogsgaard, Michael R., Koch, M., Kjær, Michael, Schiaffino, S., Mackey, Abigail & Deshmukh, Atul Shahaji, 2022, In: iScience. 25, 2, 19 p.

    Research output: Contribution to journalJournal articlepeer-review

  19. 2021
  20. Published
  21. Published

    Discovery of thymosin β4 as a human exerkine and growth factor

    Gonzalez-Franquesa, A., Stocks, Ben Nicholas, Borg, M. L., Kuefner, M., Kellezi, Emilie Dalbram, Nielsen, Thomas Svava, Agrawal, A., Pankratova, Stanislava, Chibalin, A. V., Karlsson, H. K. R., Gheibi, S., Björnholm, M., Jørgensen, Niklas Rye, Clemmensen, Christoffer, Treebak, Jonas Thue, Hostrup, Morten, Krook, A., Zierath, Juleen R & Deshmukh, Atul Shahaji, 2021, In: American Journal of Physiology: Cell Physiology. 321, 5, p. C770-C778 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  22. Published

    Insulin and 5-aminoimidazole-4-carboxamide ribonucleotide (Aicar) differentially regulate the skeletal muscle cell secretome

    Gonzalez-Franquesa, A., Peijs, Lone, Cervone, D. T., Koçana, C., Zierath, Juleen R & Deshmukh, Atul Shahaji, 2021, In: Proteomes. 9, 3, 16 p., 37.

    Research output: Contribution to journalJournal articlepeer-review

  23. Published

    Mass-spectrometry-based proteomics reveals mitochondrial supercomplexome plasticity

    Gonzalez-Franquesa, A., Stocks, Ben Nicholas, Chubanava, Sabina, Hattel, H. B., Moreno Justicia, Roger, Peijs, Lone, Treebak, Jonas Thue, Zierath, Juleen R & Deshmukh, Atul Shahaji, 2021, In: Cell Reports. 35, 8, 20 p., 109180.

    Research output: Contribution to journalJournal articlepeer-review

  24. 2020
  25. Published

    A Multi-Omics Approach to Liver Diseases: Integration of Single Nuclei Transcriptomics with Proteomics and HiCap Bulk Data in Human Liver

    Cavalli, M., Diamanti, K., Pan, G., Spalinskas, R., Kumar, C., Deshmukh, Atul Shahaji, Mann, Matthias, Sahlén, P., Komorowski, J. & Wadelius, C., 2020, In: O M I C S: A Journal of Integrative Biology. 24, 4, 15 p.

    Research output: Contribution to journalJournal articlepeer-review

  26. Published
  27. Published

    Human thermogenic adipocyte regulation by the long noncoding RNA LINC00473

    Khanh-Van Tran, Brown, E. L., DeSouza, T., Jespersen, N. Z., Nandrup-Bus, C., Yang, Q., Yang, Z., Desai, A., Min, S. Y., Rojas-Rodriguez, R., Lundh, M., Feizi, A., Willenbrock, H., Larsen, T. J., Severinsen, M. C. K., Malka, K., Mozzicato, A. M., Deshmukh, A. S., Emanuelli, B., Pedersen, B. K. & 4 others, Fitzgibbons, T., Schéele, Camilla Charlotte Nielsen, Corvera, S. & Nielsen, S., 2020, In: Nature Metabolism. 2, p. 397-412

    Research output: Contribution to journalJournal articlepeer-review

  28. 2019
  29. Published

    Mechanisms preserving insulin action during high dietary fat intake

    Lundsgaard, Anne-Marie, Holm, J. B., Sjøberg, K. A., Bojsen-Møller, K. N., Myrmel, L. S., Fjære, E., Jensen, Benjamin Anderschou Holbech, Nicolaisen, T. S., Hingst, J. R., Hansen, S. L., Doll, S., Geyer, P. E., Deshmukh, Atul Shahaji, Holst, Jens Juul, Madsen, L., Kristiansen, Karsten, Wojtaszewski, Jørgen F P, Richter, Erik A. & Kiens, Bente, 2019, In: Cell Metabolism. 29, 1, p. 50-63, e1-e4 19 p.

    Research output: Contribution to journalJournal articlepeer-review

  30. Published

    Protein aggregation capture on microparticles enables multi-purpose proteomics sample preparation

    Batth, Tanveer Singh, Tollenaere, M. A. X., Rüther, P. L., Gonzalez-Franquesa, A., Prabhakar, B. S., Bekker-Jensen, Simon Holst, Deshmukh, Atul Shahaji & Olsen, Jesper Velgaard, 2019, In: Molecular and Cellular Proteomics. 18, 5, p. 1027-1035

    Research output: Contribution to journalJournal articlepeer-review

  31. Published

    Proteomics-Based Comparative Mapping of the Secretomes of Human Brown and White Adipocytes Reveals EPDR1 as a Novel Batokine

    Deshmukh, A. S., Peijs, L., Beaudry, J. L., Jespersen, N. Z., Nielsen, C. H., Ma, T., Brunner, A. D., Larsen, T. J., Bayarri-Olmos, R., Prabhakar, B. S., Helgstrand, C., Severinsen, M. C. K., Holst, B., Kjaer, A., Tang-Christensen, M., Sanfridson, A., Garred, P., Privé, G. G., Pedersen, B. K., Gerhart-Hines, Z. & 4 others, Nielsen, S., Drucker, D. J., Mann, Matthias & Schéele, Camilla Charlotte Nielsen, 2019, In: Cell Metabolism. 30, 5, p. 963-975.e7 21 p.

    Research output: Contribution to journalJournal articlepeer-review

  32. 2018
  33. Published

    Proteomics Analysis of Skeletal Muscle from Leptin-Deficient ob/ob Mice Reveals Adaptive Remodeling of Metabolic Characteristics and Fiber Type Composition

    Schönke, M., Björnholm, M., Chibalin, A. V., Zierath, Juleen R & Deshmukh, Atul Shahaji, 2018, In: Proteomics. 18, 5-6, p. 1-11 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  34. 2017
  35. Published

    Progressive resistance training in head and neck cancer patients undergoing concomitant chemoradiotherapy

    Lonkvist, C. K., Vinther, A., Zerahn, B., Rosenbom, E., Deshmukh, Atul Shahaji, Hojman, P. & Gehl, Julie, Oct 2017, In: Laryngoscope Investigative Otolaryngology. 2, 5, p. 295-306 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  36. 2016
  37. Published

    Insulin-stimulated glucose uptake in healthy and insulin-resistant skeletal muscle

    Deshmukh, Atul Shahaji, 1 Apr 2016, In: Hormone Molecular Biology and Clinical Investigation. 26, 1, p. 13-24 12 p.

    Research output: Contribution to journalReviewpeer-review

  38. Published

    Proteomics of Skeletal Muscle: Focus on Insulin Resistance and Exercise Biology.

    Deshmukh, Atul Shahaji, 4 Feb 2016, In: Proteomes.

    Research output: Contribution to journalJournal articlepeer-review

  39. Diacylglycerol kinase-δ regulates AMPK signaling, lipid metabolism, and skeletal muscle energetics

    Jiang, L. Q., de Castro Barbosa, T., Massart, J., Deshmukh, Atul Shahaji, Löfgren, L., Duque-Guimaraes, D. E., Ozilgen, A., Osler, M. E., Chibalin, A. V. & Zierath, Juleen R, 1 Jan 2016, In: American Journal of Physiology: Endocrinology and Metabolism. 310, 1, p. E51-60

    Research output: Contribution to journalJournal articlepeer-review

  40. 2015
  41. Published

    Secretome Analysis of Lipid-Induced Insulin Resistance in Skeletal Muscle Cells by a Combined Experimental and Bioinformatics Workflow

    Deshmukh, Atul Shahaji, Cox, J., Jensen, Lars Juhl, Meissner, F. & Mann, Matthias, 6 Nov 2015, In: Journal of Proteome Research. 14, 11, p. 4885-95 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  42. Published

    Deep proteomics of mouse skeletal muscle enables quantitation of protein isoforms, metabolic pathways and transcription factors

    Deshmukh, Atul Shahaji, Murgia, M., Nagaraja, N., Treebak, Jonas Thue, Cox, J. & Mann, Matthias, Apr 2015, In: Molecular and Cellular Proteomics. 14, 4, p. 841-853

    Research output: Contribution to journalJournal articlepeer-review

  43. Absolute quantitative profiling of the key metabolic pathways in slow and fast skeletal muscle

    Rakus, D., Gizak, A., Deshmukh, Atul Shahaji & Wiśniewski, J. R., 6 Mar 2015, In: Journal of Proteome Research. 14, 3, p. 1400-11 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  44. Published

    Single muscle fiber proteomics reveals unexpected mitochondrial specialization

    Murgia, M., Nagaraj, N., Deshmukh, Atul Shahaji, Zeiler, M., Cancellara, P., Moretti, I., Reggiani, C., Schiaffino, S. & Mann, Matthias, 1 Mar 2015, In: E M B O Reports. 16, 3, p. 387-95 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  45. 2014
  46. Published

    Effects of AMPK activation on insulin sensitivity and metabolism in leptin-deficient ob/ob mice

    Zachariah Tom, R., Garcia-Roves, P. M., Sjögren, R. J. O., Jiang, L. Q., Holmström, M. H., Deshmukh, Atul Shahaji, Vieira, E., Chibalin, A. V., Björnholm, M. & Zierath, Juleen R, May 2014, In: Diabetes. 63, 5, p. 1560-71 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  47. 2012
  48. Published

    The Rab-GTPase-activating protein TBC1D1 regulates skeletal muscle glucose metabolism

    Szekeres, F., Chadt, A., Tom, R. Z., Deshmukh, Atul Shahaji, Chibalin, A. V., Björnholm, M., Al-Hasani, H. & Zierath, Juleen R, 15 Aug 2012, In: American Journal of Physiology: Endocrinology and Metabolism. 303, 4, p. E524-33

    Research output: Contribution to journalJournal articlepeer-review

  49. 2011
  50. Published

    Direct effects of FGF21 on glucose uptake in human skeletal muscle: implications for type 2 diabetes and obesity

    Mashili, F. L., Austin, R. L., Deshmukh, Atul Shahaji, Fritz, T., Caidahl, K., Bergdahl, K., Zierath, Juleen R, Chibalin, A. V., Moller, D. E., Kharitonenkov, A. & Krook, A., Mar 2011, In: Diabetes - Metabolism: Research and Reviews (Print Edition). 27, 3, p. 286-97 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  51. 2010
  52. Published

    Nitric oxide increases cyclic GMP levels, AMP-activated protein kinase (AMPK)alpha1-specific activity and glucose transport in human skeletal muscle

    Deshmukh, Atul Shahaji, Long, Y. C., de Castro Barbosa, T., Karlsson, H. K. R., Glund, S., Zavadoski, W. J., Gibbs, E. M., Koistinen, H. A., Wallberg-Henriksson, H. & Zierath, Juleen R, Jun 2010, In: Diabetologia. 53, 6, p. 1142-50 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  53. Published

    Interdependence of AMPK and SIRT1 for metabolic adaptation to fasting and exercise in skeletal muscle

    Cantó, C., Jiang, L. Q., Deshmukh, Atul Shahaji, Mataki, C., Coste, A., Lagouge, M., Zierath, Juleen R & Auwerx, J., 3 Mar 2010, In: Cell Metabolism. 11, 3, p. 213-9 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  54. 2009
  55. Published

    Role of the AMPKgamma3 isoform in hypoxia-stimulated glucose transport in glycolytic skeletal muscle

    Deshmukh, Atul Shahaji, Glund, S., Tom, R. Z. & Zierath, Juleen R, Dec 2009, In: American Journal of Physiology: Endocrinology and Metabolism. 297, 6, p. E1388-94

    Research output: Contribution to journalJournal articlepeer-review

  56. Post-transcriptional gene silencing of ribosomal protein S6 kinase 1 restores insulin action in leucine-treated skeletal muscle

    Deshmukh, Atul Shahaji, Salehzadeh, F., Metayer-Coustard, S., Fahlman, R., Nair, K. S. & Al-Khalili, L., Apr 2009, In: Cellular and molecular life sciences : CMLS. 66, 8, p. 1457-66 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  57. 2008
  58. Tbc1d1 mutation in lean mouse strain confers leanness and protects from diet-induced obesity

    Chadt, A., Leicht, K., Deshmukh, Atul Shahaji, Jiang, L. Q., Scherneck, S., Bernhardt, U., Dreja, T., Vogel, H., Schmolz, K., Kluge, R., Zierath, Juleen R, Hultschig, C., Hoeben, R. C., Schürmann, A., Joost, H. & Al-Hasani, H., 2008, In: Nature Genetics. 40, 11, p. 1354-1359 6 p.

    Research output: Contribution to journalLetterpeer-review

  59. Exercise-induced phospho-proteins in skeletal muscle

    Deshmukh, Atul Shahaji, Hawley, J. A. & Zierath, Juleen R, 2008, In: International Journal of Obesity. 32, Suppl. 4, p. S18-S23

    Research output: Contribution to journalJournal articlepeer-review

  60. Published

    Role of adenosine 5'-monophosphate-activated protein kinase subunits in skeletal muscle mammalian target of rapamycin signaling

    Deshmukh, Atul Shahaji, Treebak, Jonas Thue, Long, Y. C., Viollet, B., Wojtaszewski, Jørgen F P & Zierath, J. R., 2008, In: Molecular Endocrinology. 22, 5, p. 1105-12 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  61. 2007
  62. Interleukin-6 directly increases glucose metabolism in resting human skeletal muscle

    Glund, S., Deshmukh, Atul Shahaji, Long, Y. C., Moller, T., Koistinen, H. A., Caidahl, K., Zierath, Juleen R & Krook, A., Jun 2007, In: Diabetes. 56, 6, p. 1630-7 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  63. 2006
  64. Exercise-induced phosphorylation of the novel Akt substrates AS160 and filamin A in human skeletal muscle

    Deshmukh, Atul Shahaji, Coffey, V. G., Zhong, Z., Chibalin, A. V., Hawley, J. A. & Zierath, Juleen R, Jun 2006, In: Diabetes. 55, 6, p. 1776-82 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  65. Published

    AMPK-mediated AS160 phosphorylation in skeletal muscle is dependent on AMPK catalytic and regulatory subunits.

    Treebak, Jonas Thue, Glund, S., Deshmukh, Atul Shahaji, Klein, D. K., Long, Y. C., Jensen, Thomas Elbenhardt, Jørgensen, S. B., Viollet, B., Andersson, L., Neumann, D., Wallimann, T., Richter, Erik A., Chibalin, A. V., Zierath, J. R. & Wojtaszewski, Jørgen F P, 2006, In: Diabetes. 55, 7, p. 2051-8 7 p.

    Research output: Contribution to journalJournal articlepeer-review

ID: 119731582