The burden of disease of three food-associated heavy metals in clusters in the Danish population - Towards targeted public health strategies

Research output: Contribution to journalJournal articlepeer-review

Standard

The burden of disease of three food-associated heavy metals in clusters in the Danish population - Towards targeted public health strategies. / Herrera, Jose Alejandro Romero; Thomsen, Sofie Theresa; Jakobsen, Lea Sletting; Fagt, Sisse; Banasik, Karina; Izarzugaza, Jose M.G.; Brunak, Søren; Pires, Sara M.

In: Food and Chemical Toxicology, Vol. 150, 112072, 2021.

Research output: Contribution to journalJournal articlepeer-review

Harvard

Herrera, JAR, Thomsen, ST, Jakobsen, LS, Fagt, S, Banasik, K, Izarzugaza, JMG, Brunak, S & Pires, SM 2021, 'The burden of disease of three food-associated heavy metals in clusters in the Danish population - Towards targeted public health strategies', Food and Chemical Toxicology, vol. 150, 112072. https://doi.org/10.1016/j.fct.2021.112072

APA

Herrera, J. A. R., Thomsen, S. T., Jakobsen, L. S., Fagt, S., Banasik, K., Izarzugaza, J. M. G., Brunak, S., & Pires, S. M. (2021). The burden of disease of three food-associated heavy metals in clusters in the Danish population - Towards targeted public health strategies. Food and Chemical Toxicology, 150, [112072]. https://doi.org/10.1016/j.fct.2021.112072

Vancouver

Herrera JAR, Thomsen ST, Jakobsen LS, Fagt S, Banasik K, Izarzugaza JMG et al. The burden of disease of three food-associated heavy metals in clusters in the Danish population - Towards targeted public health strategies. Food and Chemical Toxicology. 2021;150. 112072. https://doi.org/10.1016/j.fct.2021.112072

Author

Herrera, Jose Alejandro Romero ; Thomsen, Sofie Theresa ; Jakobsen, Lea Sletting ; Fagt, Sisse ; Banasik, Karina ; Izarzugaza, Jose M.G. ; Brunak, Søren ; Pires, Sara M. / The burden of disease of three food-associated heavy metals in clusters in the Danish population - Towards targeted public health strategies. In: Food and Chemical Toxicology. 2021 ; Vol. 150.

Bibtex

@article{59d573c6a7ee46529c749ed1788604ef,
title = "The burden of disease of three food-associated heavy metals in clusters in the Danish population - Towards targeted public health strategies",
abstract = "Lifestyle and sociodemographics are likely to influence dietary patterns, and, as a result, human exposure to chemical contaminants in foods and their associated health impact. We aimed to characterize subgroups of the Danish population based on diet and sociodemographic indicators, and identify those bearing a higher disease burden due to exposure to methylmercury (MeHg), cadmium (Cd) and inorganic arsenic (i-As). We collected dietary, lifestyle, and sociodemographic data on the occurrence of chemical contaminants in foods from Danish surveys. We grouped participants according to similarities in diet, lifestyle, and sociodemographics using Self-Organizing Maps (SOM), and estimated disease burden in disability-adjusted life years (DALY). SOM clustering resulted in 12 population groups with distinct characteristics. Exposure to contaminants varied between clusters and was largely driven by intake of fish, seafood and cereal products. Five clusters had an estimated annual burden >20 DALY/100,000. The cluster with the highest burden had a high proportion of women of childbearing age, with most of the burden attributed to MeHg. Individuals belonging to the top three clusters had higher education and physical activity, were mainly non-smokers and lived in urban areas. Our findings may facilitate the development of preventive strategies targeted to the most affected subgroups.",
author = "Herrera, {Jose Alejandro Romero} and Thomsen, {Sofie Theresa} and Jakobsen, {Lea Sletting} and Sisse Fagt and Karina Banasik and Izarzugaza, {Jose M.G.} and S{\o}ren Brunak and Pires, {Sara M}",
year = "2021",
doi = "10.1016/j.fct.2021.112072",
language = "English",
volume = "150",
journal = "Food and Chemical Toxicology",
issn = "0278-6915",
publisher = "Pergamon Press",

}

RIS

TY - JOUR

T1 - The burden of disease of three food-associated heavy metals in clusters in the Danish population - Towards targeted public health strategies

AU - Herrera, Jose Alejandro Romero

AU - Thomsen, Sofie Theresa

AU - Jakobsen, Lea Sletting

AU - Fagt, Sisse

AU - Banasik, Karina

AU - Izarzugaza, Jose M.G.

AU - Brunak, Søren

AU - Pires, Sara M

PY - 2021

Y1 - 2021

N2 - Lifestyle and sociodemographics are likely to influence dietary patterns, and, as a result, human exposure to chemical contaminants in foods and their associated health impact. We aimed to characterize subgroups of the Danish population based on diet and sociodemographic indicators, and identify those bearing a higher disease burden due to exposure to methylmercury (MeHg), cadmium (Cd) and inorganic arsenic (i-As). We collected dietary, lifestyle, and sociodemographic data on the occurrence of chemical contaminants in foods from Danish surveys. We grouped participants according to similarities in diet, lifestyle, and sociodemographics using Self-Organizing Maps (SOM), and estimated disease burden in disability-adjusted life years (DALY). SOM clustering resulted in 12 population groups with distinct characteristics. Exposure to contaminants varied between clusters and was largely driven by intake of fish, seafood and cereal products. Five clusters had an estimated annual burden >20 DALY/100,000. The cluster with the highest burden had a high proportion of women of childbearing age, with most of the burden attributed to MeHg. Individuals belonging to the top three clusters had higher education and physical activity, were mainly non-smokers and lived in urban areas. Our findings may facilitate the development of preventive strategies targeted to the most affected subgroups.

AB - Lifestyle and sociodemographics are likely to influence dietary patterns, and, as a result, human exposure to chemical contaminants in foods and their associated health impact. We aimed to characterize subgroups of the Danish population based on diet and sociodemographic indicators, and identify those bearing a higher disease burden due to exposure to methylmercury (MeHg), cadmium (Cd) and inorganic arsenic (i-As). We collected dietary, lifestyle, and sociodemographic data on the occurrence of chemical contaminants in foods from Danish surveys. We grouped participants according to similarities in diet, lifestyle, and sociodemographics using Self-Organizing Maps (SOM), and estimated disease burden in disability-adjusted life years (DALY). SOM clustering resulted in 12 population groups with distinct characteristics. Exposure to contaminants varied between clusters and was largely driven by intake of fish, seafood and cereal products. Five clusters had an estimated annual burden >20 DALY/100,000. The cluster with the highest burden had a high proportion of women of childbearing age, with most of the burden attributed to MeHg. Individuals belonging to the top three clusters had higher education and physical activity, were mainly non-smokers and lived in urban areas. Our findings may facilitate the development of preventive strategies targeted to the most affected subgroups.

U2 - 10.1016/j.fct.2021.112072

DO - 10.1016/j.fct.2021.112072

M3 - Journal article

C2 - 33610621

VL - 150

JO - Food and Chemical Toxicology

JF - Food and Chemical Toxicology

SN - 0278-6915

M1 - 112072

ER -

ID: 259833559