Covalent attachment of antagonists to the a7 nicotinic acetylcholine receptor: synthesis and reactivity of substituted maleimides

Research output: Contribution to journalJournal articleResearchpeer-review

  • Joseph I Ambrus
  • Jill I Halliday
  • Nicholas Kanizaj
  • Nathan Absalom
  • Harpsøe, Kasper Skytte
  • Thomas Balle
  • Mary Chebib
  • Malcolm D McLeod
The 3-methylmaleimide congeners of the natural product methyllycaconitine (MLA) and an analogue covalently attach to functional cysteine mutants of the a7 nicotinic acetylcholine receptor (nAChR).
Original languageEnglish
JournalChemical Communications
Issue number53
Pages (from-to)6699-6701
Number of pages3
Publication statusPublished - 7 Jul 2012

ID: 38251255