The NNF Center for Protein Research

  1. 2009
  2. Published
  3. Published

    The type 2 diabetes associated minor allele of rs2237895 KCNQ1 associates with reduced insulin release following an oral glucose load

    Holmkvist, J., Banasik, K., Andersen, G., Unoki, H., Jensen, T. S., Pisinger, Charlotta Holm, Borch-Johnsen, K., Sandbaek, A., Lauritzen, T., Brunak, Søren, Maeda, S., Hansen, T. & Pedersen, Oluf Borbye, 2009, In : PLoS ONE. 4, 6, p. e5872

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Transfection of small RNAs globally perturbs gene regulation by endogenous microRNAs

    Khan, A. A., Betel, D., Miller, M. L., Sander, C., Leslie, C. S. & Marks, D. S., 2009, In : Nature Biotechnology. 27, 6, p. 549-55 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. 2008
  6. Published

    Identification of thioredoxin disulfide targets using a quantitative proteomics approach based on isotope-coded affinity tags

    Hägglund, Per Mårten, Bunkenborg, J., Maeda, K. & Svensson, B., 1 Dec 2008, In : Journal of Proteome Research. 7, 12, p. 5270-5276 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Biochemistry. Not comparable, but complementary

    Jensen, Lars Juhl & Bork, P., 3 Oct 2008, In : Science (New York, N.Y.). 322, 5898, p. 56-7 2 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  8. Published

    Lack of cross-tolerance following heat and cadmium exposure in functional MDCK monolayers

    Dokladny, K., Wharton, W., Ma, T. Y. & Moseley, Pope Lloyd, Oct 2008, In : Journal of Applied Toxicology. 28, 7, p. 885-94 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    A one-pot, simple methodology for cassette randomisation and recombination for focused directed evolution

    Hidalgo, A., Schliessmann, A., Molina, Rafael, Hermoso, J. & Bornscheuer, U. T., Sep 2008, In : Protein Engineering Design and Selection (Print). 21, 9, p. 567-76 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Exercise-induced phospho-proteins in skeletal muscle

    Deshmukh, Atul Shahaji, Hawley, J. A. & Zierath, Juleen R, Sep 2008, In : International journal of obesity (2005). 32 Suppl 4, p. S18-23

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    αAmylases. Interaction with Polysaccharide Substrates, Proteinaceous Inhibitors and Regulatory Proteins

    Seo, E. S., Nielsen, M. M., Andersen, J. M., Vester-Christensen, M. B., Jensen, J. M., Christiansen, C., Dilokpimol, A., Hachem, M. A., Hägglund, Per Mårten, Maedal, K., Finnie, C., Blennow, Andreas & Svensson, B., Sep 2008, Carbohydrate-Active Enzymes: Structure, Function and Applications. Elsevier Ltd, p. 20-36 17 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  12. Published

    The Glucose-Insulin Control System

    Hallgreen, Christine Erikstrup, Korsgaard, T. V., Hansen, R. N. & Colding-Jørgensen, M., 11 Jul 2008, Biosimulation in Drug Development. Wiley-VCH, p. 141-196 56 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  13. Published

    Crystal structures of barley thioredoxin h isoforms HvTrxh1 and HvTrxh2 reveal features involved in protein recognition and possibly in discriminating the isoform specificity

    Maeda, K., Hägglund, Per Mårten, Finnie, C., Svensson, B. & Henriksen, A., 1 Jun 2008, In : Protein Science. 17, 6, p. 1015-1024 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    A pilot project to generate affinity reagents to human proteins

    Uhlen, M., Gräslund, S. & Sundström, M., 1 Jan 2008, In : Nature Methods. 5, 10, p. 854-855 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    A large-scale analysis of tissue-specific pathology and gene expression of human disease genes and complexes

    Hansen, K. L., Hansen, N. T., Karlberg, E. O., Eklund, A. C., Roque, F. S., Donahoe, P. K., Szallasi, Z., Jensen, T. S. & Brunak, Søren, 2008, In : Proceedings of the National Academy of Science of the United States of America. 105, 52, p. 20870-5 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Cellular and molecular mechanisms of heat stress-induced up-regulation of occludin protein expression: regulatory role of heat shock factor-1

    Moseley, Pope Lloyd, 2008, In : American Journal of Pathology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Circular reasoning rather than cyclic expression

    Jensen, Lars Juhl, de Lichtenberg, U., Jensen, T. S., Brunak, Søren & Bork, P., 2008, In : Genome Biology. 9, 6, p. 403

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Classification of Laser Induced Fluorescence Spectra from Normal and Malignant bladder tissues using Learning Vector Quantization Neural Network in Bladder Cancer Diagnosis

    Karemore, Gopal, Mascarenhas, K. K., Patil, C., V.K, U., Prabhu, V., Chowla, A., Nielsen, Mads & C, S., 2008, BIBE 2008: 8th. IEEE International Conference on Bioinformatics and BioEngineering, 8-10 October 2008. IEEE Communications Society, p. 1-6 6 p.

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

  19. Published

    Drug target identification using side-effect similarity

    Campillos, M., Kuhn, M., Gavin, A., Jensen, Lars Juhl & Bork, P., 2008, In : Science. 321, 5886, p. 263-6 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    HCLK2 is required for activity of the DNA damage response kinase ATR

    Rendtlew Danielsen, J. M., Larsen, D. H., Schou, K. B., Freire, R., Falck, J., Bartek, J. & Lukas, Jiri, 2008, In : Journal of Biological Chemistry. 284, 7, p. 4140-7 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Heat shock protein 72 response to exercise in humans

    Moseley, Pope Lloyd, 2008, In : Sports Medicine.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Large-scale prediction of drug-target relationships

    Kuhn, M., Campillos, M., González, P., Jensen, Lars Juhl & Bork, P., 2008, In : F E B S Letters. 582, 8, p. 1283-90 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Linear motif atlas for phosphorylation-dependent signaling

    Miller, M. L., Jensen, Lars Juhl, Diella, F., Jørgensen, Claus Bøttcher, Tinti, M., Li, L., Hsiung, M., Parker, S. A., Bordeaux, J., Sicheritz-Ponten, T., Olhovsky, M., Pasculescu, A., Alexander, J., Knapp, S., Blom, N., Bork, P., Li, S., Cesareni, G., Pawson, T., Turk, B. E., Yaffe, M. B., Brunak, Søren & Linding, R., 2008, In : Science signaling. 1, 35, p. ra2

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Predicting biological networks from genomic data

    Harrington, E. D., Jensen, Lars Juhl & Bork, P., 2008, In : F E B S Letters. 582, 8, p. 1251-8 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    STRING 8--a global view on proteins and their functional interactions in 630 organisms

    Jensen, Lars Juhl, Kuhn, M., Stark, M., Chaffron, S., Creevey, C., Muller, J., Doerks, T., Julien, P., Roth, A., Simonovic, M., Bork, P. & von Mering, C., 2008, In : Nucleic Acids Research. 37, suppl 1, p. D412-D416 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Text mining for biology--the way forward: opinions from leading scientists

    Altman, R. B., Bergman, C. M., Blake, J., Blaschke, C., Cohen, A., Gannon, F., Grivell, L., Hahn, U., Hersh, W., Hirschman, L., Jensen, Lars Juhl, Krallinger, M., Mons, B., O'Donoghue, S. I., Peitsch, M. C., Rebholz-Schuhmann, D., Shatkay, H. & Valencia, A., 2008, In : Genome Biology (Online Edition). 9 Suppl 2, p. S7

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. 2007
  28. Published

    Barley peroxidase isozymes. Expression and post-translational modification in mature seeds as identified by two-dimensional gel electrophoresis and mass spectrometry

    Laugesen, S., Bak-Jensen, K. S., Hägglund, Per Mårten, Henriksen, A., Finnie, C., Svensson, B. & Roepstorff, P., 1 Dec 2007, In : International Journal of Mass Spectrometry. 268, 2-3, p. 244-253 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Proteomics of Disulphide and Cysteine Oxidoreduction

    Maeda, K., Hägglund, Per Mårten, Finnie, C. & Svensson, B., 16 Nov 2007, Plant Proteomics. Wiley-Blackwell Publishing, Inc., p. 71-97 27 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  30. Published

    Tuning of the FMN binding and oxido-reduction properties by neighboring side chains in Anabaena flavodoxin

    Frago, S., Goñi, G., Herguedas, B., Peregrina, J. R., Serrano, A., Perez-Dorado, I., Molina, Rafael, Gómez-Moreno, C., Hermoso, J. A., Martínez-Júlvez, M., Mayhew, S. G. & Medina, M., 15 Nov 2007, In : Archives of Biochemistry and Biophysics. 467, 2, p. 206-17 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Enhancement of the stability of a prolipase from Rhizopus oryzae toward aldehydes by saturation mutagenesis

    Di Lorenzo, M., Hidalgo, A., Molina, Rafael, Hermoso, J. A., Pirozzi, D. & Bornscheuer, U. T., Nov 2007, In : Applied and Environmental Microbiology. 73, 22, p. 7291-9 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Crystallization and preliminary X-ray diffraction studies of choline-binding protein F from Streptococcus pneumoniae

    Molina, Rafael, Gonzalez, Ana Valeria, Moscoso, M., García, P., Stelter, M., Kahn, R. & Hermoso, J. A., 1 Sep 2007, In : Acta Crystallographica Section F: Structural Biology Communications. 63, Pt 9, p. 742-5 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Four weeks one-leg training and high fat diet does not alter PPARα protein or mRNA expression in human skeletal muscle

    Helge, Jørn Wulff, Bentley, D., Schjerling, P., Willer, M., Gibala, M. J., Franch, J., Tapia-Laliena, M. A., Daugaard, J. R. & Andersen, J. L., 1 Sep 2007, In : European Journal of Applied Physiology. 101, 1, p. 105-114 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    High-affinity DNA binding sites for H-NS provide a molecular basis for selective silencing within proteobacterial genomes

    Lang, B., Blot, N., Bouffartigues, E., Buckle, M., Geertz, M., Gualerzi, C. O., Mavathur, R., Muskhelishvili, G., Pon, C. L., Rimsky, S., Stella, Stefano, Babu, M. M. & Travers, A., 1 Sep 2007, In : Nucleic Acids Research. 35, 18, p. 6330-6337 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Design and characterization of dimeric ligands cross-linking two identical modulatory AMPA receptor sites

    Kaae, B. H., Harpsøe, Kasper, Sanz, A. C., Pickering, Darryl S, Sauerberg, P., Clausen, Rasmus Prætorius, Kastrup, Jette Sandholm Jensen, Liljefors, T. & Madsen, Ulf, 19 Aug 2007, In : American Chemical Society. Abstracts of Papers (at the National Meeting). 234

    Research output: Contribution to journalConference abstract in journalResearch

  36. Published

    Breast cancer cells with acquired antiestrogen resistance are sensitized to cisplatin-induced cell death

    Yde, C. W., Gyrd-Hansen, M., Lykkesfeldt, A. E., Issinger, O. & Stenvang, Jan, Jun 2007, In : Molecular Cancer Therapeutics. 6, 6, p. 1869-1876 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Spatio-temporal profiling and degradation of alpha-amylase isozymes during barley seed germination

    Bak-Jensen, K. S., Laugesen, S., Østergaard, Ole, Finnie, C., Roepstorff, P. & Svensson, B., May 2007, In : F E B S Journal. 274, 10, p. 2552-65 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    The -35 sequence location and the Fis-sigma factor interface determine σs selectivity of the proP (P2) promoter in Escherichia coli

    Typas, A., Stella, Stefano, Johnson, R. C. & Hengge, R., 1 Feb 2007, In : Molecular Microbiology. 63, 3, p. 780-796 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Lysine 58-cleaved beta2-microglobulin is not detectable by 2D electrophoresis in ex vivo amyloid fibrils of two patients affected by dialysis-related amyloidosis

    Giorgetti, S., Stoppini, M., Tennent, G. A., Relini, A., Marchese, L., Raimondi, S., Monti, M., Marini, S., Østergaard, Ole, Heegaard, N. H. H., Pucci, P., Esposito, G., Merlini, G. & Bellotti, V., Feb 2007, In : Protein Science. 16, 2, p. 343-9 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Effect of heat acclimation on heat shock protein 72 and interleukin-10 in humans

    Moseley, Pope Lloyd, 2007, In : Journal of Applied Physiology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Heat shock protein 70 regulates cellular redox status by modulating glutathione-related enzyme activities

    Guo, S., Wharton, W., Moseley, Pope Lloyd & Shi, H., 2007, In : Cell Stress & Chaperones. 12, 3, p. 245-54 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Heat shock protein 70 regulates cellular redox status by modulating glutathione-related enzyme activities

    Moseley, Pope Lloyd, 2007, In : Cell Stress & Chaperones.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. 2006
  44. Published

    Structural Basis for Target Protein Recognition by the Protein Disulfide Reductase Thioredoxin

    Maeda, K., Hägglund, Per Mårten, Finnie, C., Svensson, B. & Henriksen, A., 1 Nov 2006, In : Structure. 14, 11, p. 1701-1710 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Cultivation of HepG2.2.15 on Cytodex-3: higher yield of hepatitis B virus and less subviral particles compared to conventional culture methods

    Lupberger, J., Mund, Andreas, Kock, J. & Hildt, E., Oct 2006, In : Journal of Hepatology. 45, 4, p. 547-52 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Environmental control of the in vivo oligomerization of nucleoid protein H-NS

    Stella, Stefano, Falconi, M., Lammi, M., Gualerzi, C. O. & Pon, C. L., 13 Jan 2006, In : Journal of Molecular Biology. 355, 2, p. 169-174 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Actin homolog MreB and RNA polymerase interact and are both required for chromosome segregation in Escherichia coli

    Kruse, Thomas, Blagoev, B., Løbner-Olesen, Anders, Wachi, M., Sasaki, K., Iwai, N., Mann, Matthias & Gerdes, K., 1 Jan 2006, In : Genes & Development. 20, 1, p. 113-124 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Interactions between Barley .ALPHA.-Amylases, Substrates, Inhibitors and Regulatory Proteins

    Abou Hachem, M., Bozonnet, S., Willemoës, Martin, C. Bønsager, B., Munch Nielsen, M., Fukuda, K., Kramhøft, B., Maeda, K., W. Sigurskjold, B., Hägglund, Per Mårten, Finnie, C., Mori, H., Robert, X., H. Jensen, M., Tranier, S., Aghajari, N., Haser, R. & Svensson, B., 1 Jan 2006, In : Journal of Applied Glycoscience. 53, 2, p. 163-169

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Elevated levels of soluble urokinase receptor in serum from mycobacteria infected patients: still looking for a marker of treatment efficacy

    Ostrowski, Sisse Rye, Ravn, P., Hoyer-Hansen, G., Ullum, Henrik & Andersen, A. B., 2006, Elevated levels of soluble urokinase receptor in serum from mycobacteria infected patients. Vol. 38. p. 1028-32 5 p. (Scandinavian Journal of Infectious Diseases. Supplementum).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  50. Published

    Heat shock protein 70 and glycoprotein 96 are differentially expressed on the surface of malignant and nonmalignant breast cells

    Moseley, Pope Lloyd, 2006, In : Cell Stress & Chaperones.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. 2005
  52. Published

    Evaluation of statistical design/modeling for prediction of the effect of amino acids on agitation-induced aggregation of human growth hormone and human insulin

    Soenderkaer, S., van de Weert, Marco, Lindgaard Hansen, L., Flink, J. & Frøkjær, Sven, 1 Nov 2005, In : Journal of Drug Delivery Science and Technology. 15, 6, p. 427-434 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Probing the determinants of substrate specificity of a feruloyl esterase, AnFaeA, from Aspergillus niger

    Faulds, C. B., Molina, Rafael, Gonzalez, R., Husband, F., Juge, N., Sanz-Aparicio, J. & Hermoso, J. A., Sep 2005, In : The F E B S Journal (Online). 272, 17, p. 4362-71 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Nature and mechanism of the in vivo oligomerization of nucleoid protein H-NS

    Stella, Stefano, Spurio, R., Falconi, M., Pon, C. L. & Gualerzi, C. O., 17 Aug 2005, In : EMBO Journal. 24, 16, p. 2896-2905 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. 2004
  56. Published

    Aspects of the barley seed proteome during development and germination

    Finnie, C., Maeda, K., Østergaard, Ole, Bak-Jensen, K. S., Larsen, J. & Svensson, B., Jun 2004, In : Biochemical Society Transactions. 32, Pt3, p. 517-9 3 p.

    Research output: Contribution to journalReviewResearchpeer-review