The NNF Center for Protein Research

  1. 2020
  2. E-pub ahead of print

    Structures of the Cmr-β Complex Reveal the Regulation of the Immunity Mechanism of Type III-B CRISPR-Cas

    Sofos, N., Feng, M., Stella, Stefano, Pape, T., Fuglsang, Anders, Lin, Jinzhong, Huang, Q., Li, Y., She, Q. & Montoya, Guillermo, 24 Jul 2020, In : Molecular Cell.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. E-pub ahead of print

    Effects of active farnesoid X receptor on GLUTag enteroendocrine L cells

    Niss, Kristoffer, Jakobsson, M. E., Westergaard, David, Belling, Kirstine G, Olsen, Jesper Velgaard & Brunak, Søren, 20 Jul 2020, In : Molecular and Cellular Endocrinology. p. 110923

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. E-pub ahead of print

    How to fix DNA-protein crosslinks

    Kühbacher, Ulrike & Duxin, Julien, 9 Jul 2020, In : DNA Repair. 94, p. 102924

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. E-pub ahead of print

    Mutant FOXL2C134W highjacks SMAD4 and SMAD2/3 to drive adult granulosa cell tumors

    Weis-Banke, S. E., Lerdrup, Mads, Kleine-Kohlbrecher, D., Mohammad, F., Sidoli, S., Jensen, O. N., Yanase, T., Nakamura, T., Iwase, A., Stylianou, A., Abu-Rustum, N. R., Aghajanian, C., Soslow, R., Da Cruz Paula, A., Koche, R. P., Weigelt, B., Christensen, Jesper, Helin, Kristian & Cloos, Paul, 8 Jul 2020, In : Cancer Research.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. E-pub ahead of print

    Accurate MS-based Rab10 phosphorylation stoichiometry determination as readout for LRRK2 activity in Parkinson's disease

    Karayel, O., Tonelli, F., Virreira Winter, S., Geyer, P. E., Fan, Y., Sammler, E. M., Alessi, D., Steger, M. & Mann, Matthias, 29 Jun 2020, In : Molecular and Cellular Proteomics.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Sequencing of the First Draft of the Human Acetylome

    Choudhary, Chuna Ram & Mann, Matthias, 1 Jun 2020, In : Clinical Chemistry. 66, 6, p. 852-853 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Predicting and elucidating the etiology of fatty liver disease: A machine learning modeling and validation study in the IMI DIRECT cohorts

    IMI-DIRECT consortium, I. C., Jun 2020, In : PLoS Medicine. 17, 6, p. e1003149

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Quantitative proteomics characterization of acutely isolated primary adult rat cardiomyocytes and fibroblasts

    Poulsen, P. C., Schrölkamp, Maren, Bagwan, Navratan, Leurs, U., Humphries, E. S. A., Bomholzt, S. H., Nielsen, Morten Schak, Bentzen, Bo Hjorth, Olsen, Jesper Velgaard & Lundby, Alicia, Jun 2020, In : Journal of Molecular and Cellular Cardiology. 143, p. 63-70 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. E-pub ahead of print

    Disease Trajectories for Hidradenitis Suppurativa in the Danish Population

    Kjærsgaard Andersen, R., Jørgensen, Isabella Friis, Reguant, Roc, Jemec, Gregor & Brunak, Søren, 20 May 2020, In : JAMA Dermatology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. E-pub ahead of print

    Integrative Analysis Identifies Key Molecular Signatures Underlying Neurodevelopmental Deficits in Fragile X Syndrome

    Utami, K. H., Skotte, Niels Henning, Colaço, A. R., Yusof, N. A. B. M., Sim, B., Yeo, X. Y., Bae, H., Garcia-Miralles, M., Radulescu, C. I., Chen, Q., Chaldaiopoulou, G., Liany, H., Nama, S., Peteri, U. A., Sampath, P., Castrén, M. L., Jung, S., Mann, Matthias & Pouladi, M. A., 13 May 2020, In : Biological Psychiatry.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. E-pub ahead of print

    Mendelian randomization analysis does not support causal associations of birth weight with hypertension risk and blood pressure in adulthood

    Zheng, Y., Huang, T., Wang, T., Mei, Z., Sun, Z., Zhang, T., Ellervik, Christina, Chai, J., Sim, X., van Dam, R. M., Tai, E., Koh, W., Dorajoo, R., Saw, S., Sabanayagam, C., Wong, T. Y., Gupta, P., Rossing, Peter, Ahluwalia, T. S., Vinding, R. K., Bisgaard, Hans, Bønnelykke, Klaus, Wang, Y., Graff, M., Voortman, T., van Rooij, F. J. A., Hofman, A., van Heemst, D., Noordam, R., Estampador, A. C., V Varga, Tibor, Enzenbach, C., Scholz, M., Thiery, J., Burkhardt, R., Orho-Melander, M., Schulz, C., Ericson, U., Sonestedt, E., Kubo, M., Akiyama, M., Zhou, A., Oskari Kilpeläinen, Tuomas, Hansen, Torben, Kleber, M. E., Delgado, G., McCarthy, M., Lemaitre, R. N., Felix, J. F., Jaddoe, V. W. V., Wu, Y., Mohlke, K. L., Lehtimäki, T., Wang, C. A., Pennell, C. E., Schunkert, H., Kessler, T., Zeng, L., Willenborg, C., Peters, A., Lieb, W., Grote, V., Rzehak, P., Koletzko, B., Erdmann, J., Munz, M., Wu, T., He, M., Yu, C., Lecoeur, C., Froguel, P., Corella, D., Moreno, L. A., Lai, C., Pitkänen, N., Boreham, C. A., Ridker, P. M., Rosendaal, F. R., de Mutsert, R., Power, C., Paternoster, L., Sørensen, Thorkild I.A., Tjønneland, Anne, Overvad, K., Djousse, L., Rivadeneira, F., Lee, N. R., Raitakari, O. T., Kähönen, M., Viikari, J., Langhendries, J., Escribano, J., Verduci, E., Dedoussis, G., König, I., Balkau, B., Coltell, O., Dallongeville, J., Meirhaeghe, A., Amouyel, P., Gottrand, F., Pahkala, K., Niinikoski, H., Hyppönen, E., März, W., Mackey, D. A., Gruszfeld, D., Tucker, K. L., Fumeron, F., Estruch, R., Ordovas, J. M., Arnett, D. K., Mook-Kanamori, D. O., Mozaffarian, D., Psaty, B. M., North, K. E., Chasman, D. I. & Qi, L., 7 May 2020, In : European Journal of Epidemiology. 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. E-pub ahead of print

    Predictors of weight loss after bariatric surgery - a cross-disciplinary approach combining physiological, social, and psychological measures

    Nielsen, Mette Søndergaard, Christensen, B. J., Schmidt, J. B., Tækker, L., Holm, Lotte, Lunn, Susanne, Ritz, Christian, Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Schnurr, Theresia Maria, Hansen, Torben, le Roux, C. W., Lund, Thomas Bøker, Floyd, A. K. & Sjödin, Anders Mikael, 23 Apr 2020, In : International Journal of Obesity.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    The dental proteome of Homo antecessor

    Welker, Frido, Ramos Madrigal, Jazmin, Gutenbrunner, P., Mackie, Meaghan, Tiwary, S., Rakownikow Jersie-Christensen, R., Chiva, C., Dickinson, M. R., Kuhlwilm, M., de Manuel, M., Gelabert, P., Martinón-Torres, M., Margvelashvili, A., Arsuaga, J. L., Carbonell, E., Marques-Bonet, T., Penkman, K., Sabidó, E., Cox, J., Olsen, Jesper Velgaard, Lordkipanidze, D., Racimo, Fernando, Lalueza-Fox, C., Bermúdez de Castro, J. M., Willerslev, Eske & Cappellini, Enrico, Apr 2020, In : Nature. 580, 7802, p. 235-238 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Direct Observation of CRISPR-Cas12 Conformational Sampling by SM FRET and Cryo EM Reveals how Conformational Activation Promotes Catalysis and Resetting of the Endonuclease Activity

    Stella, Stefano, Mesa, Pablo, Thomsen, J., Paul, Bijoya, Alcon, P., Jensen, Simon Bo, Moses, M. E., Montoya, Guillermo & Hatzakis, Nikos, 7 Feb 2020, In : Biophysical Journal. 118, 3, p. 223A-224A 2 p.

    Research output: Contribution to journalConference abstract in journalResearch

  16. Published

    Quantitative and Dynamic Catalogs of Proteins Released during Apoptotic and Necroptotic Cell Death

    Tanzer, M. C., Frauenstein, A., Stafford, C. A., Phulphagar, K., Mann, Matthias & Meissner, F., 28 Jan 2020, In : Cell Reports. 30, 4, p. 1260-1270.e5

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    The human methyltransferase ZCCHC4 catalyses N6-methyladenosine modification of 28S ribosomal RNA

    Pinto, R., Vågbø, C. B., Jakobsson, M. E., Kim, Y., Baltissen, M. P., O'Donohue, M., Guzmán, U. H., Małecki, J. M., Wu, J., Kirpekar, F., Olsen, Jesper Velgaard, Gleizes, P., Vermeulen, M., Leidel, S. A., Slupphaug, G. & Falnes, P. Ø., 24 Jan 2020, In : Nucleic Acids Research. 48, 2, p. 830-846 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Trapped ion mobility spectrometry and PASEF enable in-depth lipidomics from minimal sample amounts

    Vasilopoulou, C. G., Sulek, Karolina, Brunner, A., Meitei, N. S., Schweiger-Hufnagel, U., Meyer, S. W., Barsch, A., Mann, Matthias & Meier, F., 16 Jan 2020, In : Nature Communications. 11, 1, p. 331

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. E-pub ahead of print

    Gut microbial changes of patients with psychotic and affective disorders: A systematic review

    Vindegaard, N., Speyer, H., Nordentoft, Merete, Rasmussen, S. & Benros, M. E., 14 Jan 2020, In : Schizophrenia Research.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Treacle controls the nucleolar response to rDNA breaks via TOPBP1 recruitment and ATR activation

    Mooser, C., Symeonidou, I., Leimbacher, P., Ribeiro, A., Shorrocks, A. K., Jungmichel, S., Buch-Larsen, Sara Charlotte, Knechtle, K., Jasrotia, A., Zurbriggen, D., Jeanrenaud, A., Leikauf, C., Fink, D., Nielsen, Michael Lund, Blackford, A. N. & Stucki, M., 8 Jan 2020, In : Nature Communications. 11, 1, p. 123

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Higher burden of rare frameshift indels in genes related to synaptic transmission separate familial hemiplegic migraine from common types of migraine

    Rasmussen, A. H., Olofsson, I., Chalmer, M. A., Olesen, Jes & Hansen, Thomas Folkmann, 1 Jan 2020, In : Journal of Medical Genetics. 106640.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    A Compact Quadrupole-Orbitrap Mass Spectrometer with FAIMS Interface Improves Proteome Coverage in Short LC Gradients

    Bekker-Jensen, D. B., Martinez Del Val, Ana, Steigerwald, S., Rüther, Patrick, Fort, K. L., Arrey, T. N., Harder, A., Makarov, A. & Olsen, Jesper Velgaard, 2020, In : Molecular and Cellular Proteomics. 19, 4, p. 716-729 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    A Multi-Omics Approach to Liver Diseases: Integration of Single Nuclei Transcriptomics with Proteomics and HiCap Bulk Data in Human Liver

    Cavalli, M., Diamanti, K., Pan, G., Spalinskas, R., Kumar, C., Deshmukh, Atul Shahaji, Mann, Matthias, Sahlén, P., Komorowski, J. & Wadelius, C., 2020, In : O M I C S: A Journal of Integrative Biology. 24, 4, 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    A draft genome sequence of the elusive giant squid, Architeuthis dux

    Rodrigues da Fonseca, Rute Andreia, Couto, A., Machado, A. M., Brejova, B., Albertin, C. B., Silva, F., Gardner, P., Baril, T., Hayward, A., Campos, A., Ribeiro, Â. M., Barrio-Hernandez, I., Hoving, H., Tafur-Jimenez, R., Chu, C., Frazão, B., Petersen, Bent, Peñaloza, F., Musacchia, F., Alexander, G. C., Osório, H., Winkelmann, I., Simakov, O., Rasmussen, Simon, Rahman, M. Z., Pisani, D., Vinther, J., Jarvis, E., Zhang, Guojie, Strugnell, J. M., Castro, L. F. C., Fedrigo, O., Patricio, M., Li, Q., Rocha, S., Antunes, A., Wu, Y., Ma, B., Sanges, R., Vinar, T., Blagoev, B., Sicheritz-Pontén, Thomas, Nielsen, Rasmus & Gilbert, M Thomas P, 2020, In : GigaScience. 9, 1, 12 p., giz152.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    A dynamic charge-charge interaction modulates PP2A:B56 substrate recruitment

    Wang, X., Garvanska, Dimitriya Hristoforova, Nasa, I., Ueki, Yumi, Zhang, G., Kettenbach, A. N., Peti, W., Nilsson, Jakob & Page, R., 2020, In : eLife. 9, 19 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    A streamlined mass spectrometry-based proteomics workflow for large scale FFPE tissue analysis

    Coscia, Fabian, Doll, S., Bech, Jacob Mathias, Schweizer, L., Mund, Andreas, Lengyel, E., Lindebjerg, J., Madsen, G. I., Moreira, José & Mann, Matthias, 2020, In : Journal of Pathology. 251, p. 110-112

    Research output: Contribution to journalJournal articleResearchpeer-review

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