The NNF Center for Protein Research

  1. Published

    4.0-A resolution cryo-EM structure of the mammalian chaperonin TRiC/CCT reveals its unique subunit arrangement

    Cong, Y., Baker, M. L., Jakana, J., Woolford, D., Miller, E. J., Reissmann, S., Kumar, R. N., Redding-Johanson, A. M., Batth, Tanveer Singh, Mukhopadhyay, A., Ludtke, S. J., Frydman, J. & Chiu, W., 16 Mar 2010, In : Proceedings of the National Academy of Sciences of the United States of America. 107, 11, p. 4967-72 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    5'-Cytosine-phosphoguanine (CpG) methylation impacts the activity of natural and engineered meganucleases

    Valton, J., Daboussi, F., Leduc, S., Molina, Rafael, Redondo, P., Macmaster, R., Montoya, Guillermo & Duchateau, P., 31 Aug 2012, In : The Journal of Biological Chemistry. 287, 36, p. 30139-50 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    52 Genetic Loci Influencing Myocardial Mass

    van der Harst, P., van Setten, J., Verweij, N., Vogler, G., Franke, L., Maurano, M. T., Wang, X., Mateo Leach, I., Eijgelsheim, M., Sotoodehnia, N., Hayward, C., Sorice, R., Meirelles, O., Lyytikäinen, L., Polašek, O., Tanaka, T., Arking, D. E., Ulivi, S., Trompet, S., Müller-Nurasyid, M., Smith, A. V., Dörr, M., Kerr, K. F., Magnani, J. W., Del Greco M, F., Zhang, W., Nolte, I. M., Silva, C. T., Padmanabhan, S., Tragante, V., Esko, T., Abecasis, G. R., Adriaens, M. E., Andersen, K., Barnett, P., Bis, J. C., Bodmer, R., Buckley, B. M., Campbell, H., Cannon, M. V., Chakravarti, A., Chen, L. Y., Delitala, A., Devereux, R. B., Doevendans, P. A., Dominiczak, A. F., Ferrucci, L., Ford, I., Gieger, C., Harris, T. B., Haugen, E., Heinig, M., Hernandez, D. G., Hillege, H. L., Hirschhorn, J. N., Hofman, A., Hubner, N., Hwang, S., Iorio, A., Kähönen, M., Kellis, M., Kolcic, I., Kooner, I. K., Kooner, J. S., Kors, J. A., Lakatta, E. G., Lage, K., Launer, L. J., Levy, D., Lundby, Alicia, Macfarlane, P. W., May, D., Meitinger, T., Metspalu, A., Nappo, S., Naitza, S., Neph, S., Nord, A. S., Nutile, T., Okin, P. M., Olsen, Jesper Velgaard, Oostra, B. A., Penninger, J. M., Pennacchio, L. A., Pers, Tune H, Perz, S., Peters, A., Pinto, Y. M., Pfeufer, A., Pilia, M. G., Pramstaller, P. P., Prins, B. P., Raitakari, O. T., Raychaudhuri, S., Rice, K. M., Rossin, E. J., Rotter, J. I., Schafer, S., Schlessinger, D., Schmidt, C. O., Sehmi, J., Silljé, H. H. W., Sinagra, G., Sinner, M. F., Slowikowski, K., Soliman, E. Z., Spector, T. D., Spiering, W., Stamatoyannopoulos, J. A., Stolk, R. P., Strauch, K., Tan, S., Tarasov, K. V., Trinh, B., Uitterlinden, A. G., van den Boogaard, M., van Duijn, C. M., van Gilst, W. H., Viikari, J. S., Visscher, P. M., Vitart, V., Völker, U., Waldenberger, M., Weichenberger, C. X., Westra, H., Wijmenga, C., Wolffenbuttel, B. H., Yang, J., Bezzina, C. R., Munroe, P. B., Snieder, H., Wright, A. F., Rudan, I., Boyer, L. A., Asselbergs, F. W., van Veldhuisen, D. J., Stricker, B. H., Psaty, B. M., Ciullo, M., Sanna, S., Lehtimäki, T., Wilson, J. F., Bandinelli, S., Alonso, A., Gasparini, P., Jukema, J. W., Kääb, S., Gudnason, V., Felix, S. B., Heckbert, S. R., de Boer, R. A., Newton-Cheh, C., Hicks, A. A., Chambers, J. C., Jamshidi, Y., Visel, A., Christoffels, V. M., Isaacs, A., Samani, N. J. & de Bakker, P. I. W., 27 Sep 2016, In : Journal of the American College of Cardiology. 68, 13, p. 1435-48 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    53BP1 fosters fidelity of homology-directed DNA repair

    Ochs, F., Somyajit, Kumar, Altmeyer, M., Rask, M. D., Lukas, Jiri & Lukas, Claudia, Aug 2016, In : Nature Structural and Molecular Biology. 23, 8, p. 714-21 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    53BP1 mediates productive and mutagenic DNA repair through distinct phosphoprotein interactions

    Callen, E., Wong, N., Chen, H., Faryabi, R. B., Polato, F., Santos, M., Nussenzweig, A., Kruhlak, M. J., Di Virgilio, M., Nussenzweig, M. C., Nieto-Soler, M., Fernandez-Capetillo, O., Starnes, L. M., Daniel, J. A., Wesemann, D. R., Alt, F. W., Lee, J., Ge, K., Tubbs, A. & Sleckman, B. P., 6 Jun 2013, In : Cell. 153, 6, p. 1266-1280 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    53BP1 nuclear bodies enforce replication timing at under-replicated DNA to limit heritable DNA damage

    Spies, Julian, Lukas, Claudia, Somyajit, Kumar, Rask, M., Lukas, Jiri & Neelsen, K. J., 2019, In : Nature Cell Biology. 21, p. 487-497

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    53BP1 nuclear bodies form around DNA lesions generated by mitotic transmission of chromosomes under replication stress

    Lukas, Claudia, Savic, V., Bekker-Jensen, Simon Holst, Doil, C., Neumann, B., Pedersen, R. S., Grøfte, M., Chan, K. L., Hickson, Ian David, Bartek, J. & Lukas, Jiri, 1 Mar 2011, In : Nature Cell Biology. 13, 3, p. 243-53 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    In vivo quantitative phosphoproteomic profiling identifies novel regulators of castration-resistant prostate cancer growth

    Jiang, N., Hjorth-Jensen, K., Hekmat, O., Iglesias Gato, Diego, Kruse, Thomas, Wang, C., Wei, W., Ke, B., Yan, B., Niu, Y., Olsen, Jesper Velgaard & Flores Morales, A., 2015, In : Oncogene. 34, p. 2764–2776 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    LocText: relation extraction of protein localizations to assist database curation

    Cejuela, J. M., Vinchurkar, S., Goldberg, T., Prabhu Shankar, M. S., Baghudana, A., Bojchevski, A., Uhlig, C., Ofner, A., Raharja-Liu, P., Jensen, Lars Juhl & Rost, B., 2018, In : BMC Bioinformatics. 19, p. 1-11 15.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    miR-625-3p regulates oxaliplatin resistance by targeting MAP2K6-p38 signalling in human colorectal adenocarcinoma cells

    Rasmussen, M. H., Lyskjær, I., Jersie-Christensen, R. R., Tarpgaard, L. S., Primdal-Bengtson, B., Nielsen, M. M., Pedersen, J. S., Kuhlmann, Tine Plato, Hansen, F., Olsen, Jesper Velgaard, Pfeiffer, P., Ørntoft, T. F. & Andersen, C. L., 2016, In : Nature Communications. 7, 15 p., 12436.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published
  12. Published

    A Brief History of Protein Sorting Prediction

    Nielsen, H., Tsirigos, Konstantinos, Brunak, Søren & von Heijne, G., 2019, In : The Protein Journal. 38, 3, p. 200-216 17 p.

    Research output: Contribution to journalReviewResearchpeer-review

  13. Published

    A Compact Quadrupole-Orbitrap Mass Spectrometer with FAIMS Interface Improves Proteome Coverage in Short LC Gradients

    Bekker-Jensen, D. B., Martinez Del Val, Ana, Steigerwald, S., Rüther, Patrick, Fort, K. L., Arrey, T. N., Harder, A., Makarov, A. & Olsen, Jesper Velgaard, 2020, In : Molecular and Cellular Proteomics. 19, 4, p. 716-729 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    A Consensus Binding Motif for the PP4 Protein Phosphatase

    Ueki, Yumi, Kruse, Thomas, Weisser, Melanie, Sundell, G. N., Larsen, M. S. Y., Mendez, B. L., Jenkins, N. P., Garvanska, Dimitriya Hristoforova, Cressey, L., Zhang, G., Davey, N., Montoya, Guillermo, Ivarsson, Y., Kettenbach, A. N. & Nilsson, Jakob, 2019, In : Molecular Cell. 76, 6, p. 953-964.e6

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    A Conserved Motif Provides Binding Specificity to the PP2A-B56 Phosphatase

    Hertz, Emil Peter Thrane, Kruse, Thomas, Davey, N. E., López-Méndez, B., Sigurdsson, J. O., Montoya, Guillermo, Olsen, Jesper Velgaard & Nilsson, Jakob, 2016, In : Molecular Cell. 63, 4, p. 686-695 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    A Genome-Wide Association Study of IVGTT-Based Measures of First Phase Insulin Secretion Refines the Underlying Physiology of Type 2 Diabetes Variants

    Wood, A. R., Jonsson, Anna Elisabet, Jackson, A. U., Wang, T., van Leewen, N., Palmer, N. D., Kobes, S., Deelen, J., Boquete-Vilarino, L., Paananen, J., Stančáková, A., Boomsma, D. I., de Geus, E. J., Eekhoff, E. M., Fritsche, A., Kramer, M., Nijpels, G., Simonis-Bik, A. M. C., van Haeften, T. W., Mahajan, A., Boehnke, M., Bergman, R. N., Tuomilehto, J., Collins, F. S., Mohlke, K. L., Banasik, Karina, Groves, C. J., McCarthy, M. I., Pearson, E. R., Natali, A., Mari, A., Buchanan, T. A., Taylor, K. D., Xiang, A. H., Gjesing, Anette Marianne Prior, Grarup, Niels, Eiberg, Hans Rudolf Lytchoff, Pedersen, Oluf Borbye, Chen, Y., Laakso, M., Norris, J. M., Smith, U., Wagenknecht, L. E., Baier, L., Bowden, D. W., Hansen, Torben, Walker, M., Watanabe, R. M., 't Hart, L. M., Hanson, R. L. & Frayling, T. M., 2017, In : Diabetes. 66, 8, p. 2296-2309

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    A Guide to Dictionary-Based Text Mining

    Cook, H. V. & Jensen, Lars Juhl, 2019, Bioinformatics and Drug Discovery. Larson, R. S. & Oprea, T. I. (eds.). 3 ed. Humana Press, Vol. 1939. p. 73-89 17 p. (Methods in Molecular Biology).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  18. Published

    A Major Lineage of Enteroendocrine Cells Coexpress CCK, Secretin, GIP, GLP-1, PYY, and Neurotensin but Not Somatostatin

    Egerod, Kristoffer Lihme, Engelstoft, M. S., Grunddal, K. V., Nøhr, Mark Klitgaard, Secher, A., Sakata, I., Pedersen, J., Windeløv, Johanne Agerlin, Füchtbauer, E., Olsen, Jørgen, Sundler, F., Christensen, Jan Pravsgaard, Wierup, N., Olsen, Jesper Velgaard, Holst, Jens Juul, Zigman, J. M., Poulsen, Steen Seier & Schwartz, Thue W., 1 Dec 2012, In : Endocrinology. 153, 12, p. 5782-95 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    A Map of General and Specialized Chromatin Readers in Mouse Tissues Generated by Label-free Interaction Proteomics

    Eberl, H. C., Mann, M., Spruijt, C. G., Vermeulen, M. & Kelstrup, C. D., 24 Jan 2013, In : Molecular Cell. 49, 2, p. 368-378 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    A Multi-Omics Approach to Liver Diseases: Integration of Single Nuclei Transcriptomics with Proteomics and HiCap Bulk Data in Human Liver

    Cavalli, M., Diamanti, K., Pan, G., Spalinskas, R., Kumar, C., Deshmukh, Atul Shahaji, Mann, Matthias, Sahlén, P., Komorowski, J. & Wadelius, C., 16 Mar 2020, In : O M I C S: A Journal of Integrative Biology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    A Multilaboratory Comparison of Calibration Accuracy and the Performance of External References in Analytical Ultracentrifugation

    Zhao, H., Ghirlando, R., Alfonso, C., Arisaka, F., Attali, I., Bain, D. L., Bakhtina, M. M., Becker, D. F., Bedwell, G. J., Bekdemir, A., Besong, T. M. D., Birck, C., Brautigam, C. A., Brennerman, W., Byron, O., Bzowska, A., Chaires, J. B., Chaton, C. T., Cölfen, H., Connaghan, K. D., Crowley, K. A., Curth, U., Daviter, T., Dean, W. L., Díez, A. I., Ebel, C., Eckert, D. M., Eisele, L. E., Eisenstein, E., England, P., Escalante, C., Fagan, J. A., Fairman, R., Finn, R. M., Fischle, W., de la Torre, J. G., Gor, J., Gustafsson, H., Hall, D., Harding, S. E., Cifre, J. G. H., Herr, A. B., Howell, E. E., Isaac, R. S., Jao, S., Jose, D., Kim, S., Kokona, B., Kornblatt, J. A., Kosek, D., Krayukhina, E., Krzizike, D., Kusznir, E. A., Kwon, H., Larson, A., Laue, T. M., Le Roy, A., Leech, A. P., Lilie, H., Luger, K., Luque-Ortega, J. R., Ma, J., May, C. A., Maynard, E. L., Modrak-Wojcik, A., Mok, Y., Mücke, N., Nagel-Steger, L., Narlikar, G. J., Noda, M., Nourse, A., Obsil, T., Park, C. K., Park, J., Pawelek, P. D., Perdue, E. E., Perkins, S. J., Perugini, M. A., Peterson, C. L., Peverelli, M. G., Piszczek, G., Prag, G., Prevelige, P. E., Raynal, B. D. E., Rezabkova, L., Richter, K., Ringel, A. E., Rosenberg, R., Rowe, A. J., Rufer, A. C., Scott, D. J., Seravalli, J. G., Solovyova, A. S., Song, R., Staunton, D., Stoddard, C., Stott, K., Strauss, H. M., Streicher, W. W., Sumida, J. P., Swygert, S. G., Szczepanowski, R. H., Tessmer, I., Toth, R. T., Tripathy, A., Uchiyama, S., Uebel, S. F. W., Unzai, S., Gruber, A. V., von Hippel, P. H., Wandrey, C., Wang, S., Weitzel, S. E., Wielgus-Kutrowska, B., Wolberger, C., Wolff, M., Wright, E., Wu, Y., Wubben, J. M. & Schuck, P., 21 May 2015, In : PLOS ONE. 10, 5, 30 p., e0126420.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    A Novel Familial Cardiac Arrhythmia Syndrome with Widespread ST-Segment Depression

    Bundgård, Henning, Jøns, C., Lodder, E. M., Izarzugaza, J. M. G., Romero Herrera, Jose Alejandro, Pehrson, S., Tfelt-Hansen, Jacob, Ahlberg, G., Olesen, Morten Steen Salling, Holst, A. G., Wellens, H., de Villiers, C., Hastings, R., Stuart, G., Brunak, Søren, Wilde, A. A. M., Watkins, H. & Christensen, A. H., 2018, In : The New England Journal of Medicine. 379, 18, p. 1780-1781 2 p.

    Research output: Contribution to journalComment/debateResearch

  23. Published

    A Novel Role of Human Holliday Junction Resolvase GEN1 in the Maintenance of Centrosome Integrity

    Gao, M., Danielsen, J. M. R., Wei, L., Zhou, D., Xu, Q., Li, M., Yang, Y., Wang, Z. & Tong, W., 16 Nov 2012, In : P L o S One. 7, 11, 13 p., e49687.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    A PTIP-PA1 subcomplex promotes transcription for IgH class switching independently from the associated MLL3/MLL4 methyltransferase complex

    Starnes, L. M., Su, D., Pikkupeura, Laura Maarit, Weinert, B. T., Santos, M. A., Mund, Andreas, Soria, R., Cho, Y., Pozdnyakova, I., Kubec Højfeldt, M., Lages Lino Vala, A., Yang, W., López-Méndez, B., Lee, J., Peng, W., Yuan, J., Ge, K., Montoya, Guillermo, Nussenzweig, A., Choudhary, Chuna Ram & Daniel, J. A., 15 Jan 2016, In : Genes & Development. 30, 2, p. 149-163 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    A Primer on Concepts and Applications of Proteomics in Neuroscience

    Hosp, F. & Mann, Matthias, 1 Nov 2017, In : Neuron. 96, 3, p. 558-571 14 p.

    Research output: Contribution to journalReviewResearchpeer-review

  26. Published

    A Proteome-wide, Quantitative Survey of In Vivo Ubiquitylation Sites Reveals Widespread Regulatory Roles

    Wagner, S. A., Beli, P., Weinert, B. T., Nielsen, Michael Lund, Cox, J., Mann, Matthias & Choudhary, Chuna Ram, 1 Oct 2011, In : Molecular and Cellular Proteomics. 10, 10, p. M111.013284

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    A RIPK2 inhibitor delays NOD signalling events yet prevents inflammatory cytokine production

    Nachbur, U., Stafford, C. A., Bankovacki, A., Zhan, Y., Lindqvist, L. M., Fiil, B. K., Khakham, Y., Ko, H., Sandow, J. J., Falk, H., Holien, J. K., Chau, D., Hildebrand, J., Vince, J. E., Sharp, P. P., Webb, A. I., Jackman, K. A., Mühlen, S., Kennedy, C. L., Lowes, K. N., Murphy, J. M., Gyrd-Hansen, M., Parker, M. W., Hartland, E. L., Lew, A. M., Huang, D. C. S., Lessene, G. & Silke, J., 17 Mar 2015, In : Nature Communications. 6, 13 p., 6442.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    A Small Molecule Inhibitor of the BLM Helicase Modulates Chromosome Stability in Human Cells

    Nguyen, G. H., Dexheimer, T. S., Rosenthal, A. S., Chu, W. K., Singh, D. K., Mosedale, G., Bachrati, C. Z., Schultz, L., Sakurai, M., Savitsky, P., Abu, M., McHugh, P. J., Bohr, Vilhelm, Harris, C. C., Jadhav, A., Gileadi, O., Maloney, D. J., Simeonov, A. & Hickson, Ian David, 24 Jan 2013, In : Chemistry & Biology. 20, 1, p. 55-62 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    A Type III-B Cmr effector complex catalyzes the synthesis of cyclic oligoadenylate second messengers by cooperative substrate binding

    Han, W., Stella, Stefano, Zhang, Y., Guo, Tong, Sulek, Karolina, Peng-Lundgren, L., Montoya, Guillermo & She, Q., 2018, In : Nucleic Acids Research. 46, 19, p. 10319-10330 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    A comparison of protein kinases inhibitor screening methods using both enzymatic activity and binding affinity determination

    Rudolf, A. F., Skovgaard, T., Knapp, S., Jensen, Lars Juhl & Berthelsen, J., 2014, In : PloS one. 9, 6, p. 1-5 6 p., e98800.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    A complement to the modern crystallographer's toolbox: caged gadolinium complexes with versatile binding modes

    Stelter, M., Molina, Rafael, Jeudy, S., Kahn, R., Abergel, C. & Hermoso, J. A., Jun 2014, In : Acta crystallographica. Section D, Biological crystallography. 70, Pt 6, p. 1506-16 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    A comprehensive and quantitative comparison of text-mining in 15 million full-text articles versus their corresponding abstracts

    Westergaard, David, Stærfeldt, H., Tønsberg, C., Jensen, Lars Juhl & Brunak, Søren, 2018, In : PLoS Computational Biology. 14, 2, 16 p., e1005962.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    A comprehensive compilation of SUMO proteomics

    Hendriks, Ivo Alexander & Vertegaal, A. C. O., Sep 2016, In : Nature Reviews. Molecular Cell Biology. 17, 9, p. 581-95 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    A comprehensive platform for the analysis of ubiquitin-like protein modifications using in vivo biotinylation

    Pirone, L., Xolalpa, W., Sigurdsson, J. O., Ramirez, J., Pérez, C., González, M., de Sabando, A. R., Elortza, F., Rodriguez, M. S., Mayor, U., Olsen, Jesper Velgaard, Barrio, R. & Sutherland, J. D., 2017, In : Scientific Reports. 7, 17 p., 40756.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    A computational approach to chemical etiologies of diabetes

    Audouze, K. M. L., Brunak, Søren & Grandjean, P., 19 Sep 2013, In : Scientific Reports. 3, p. 2712 2712.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    A computational framework to integrate high-throughput "-omics" datasets for the identification of potential mechanistic links

    Pedersen, Helle Krogh, Forslund, S. K., Gudmundsdottir, V., Petersen, A. Ø., Hildebrand, F., Hyötyläinen, T., Nielsen, Trine, Hansen, Torben, Bork, P., Ehrlich, S. D., Brunak, Søren, Oresic, M., Pedersen, Oluf Borbye & Nielsen, H. B., 2018, In : Nature Protocols. 13, 12, p. 2781-2800 20 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    A computational method for identification of vaccine targets from protein regions of conserved human leukocyte antigen binding

    Olsen, L. R., Simon, C., Kudahl, U. J., Bagger, F. O., Winther, Ole, Reinherz, E. L., Zhang, G. L. & Brusic, V., 2015, In : B M C Medical Genomics. 8, Suppl 4, 6 p., 5.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    A direct role of Mad1 in the spindle assembly checkpoint beyond Mad2 kinetochore recruitment

    Kruse, Thomas, Larsen, M. S. Y., Sedgwick, G. G., Sigurdsson, J. O., Streicher, W., Olsen, Jesper Velgaard & Nilsson, Jakob, 29 Jan 2014, In : E M B O Reports. 15, p. 282-290

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    A draft genome sequence of the elusive giant squid, Architeuthis dux

    Rodrigues da Fonseca, Rute Andreia, Couto, A., Machado, A. M., Brejova, B., Albertin, C. B., Silva, F., Gardner, P., Baril, T., Hayward, A., Campos, A., Ribeiro, Â. M., Barrio-Hernandez, I., Hoving, H., Tafur-Jimenez, R., Chu, C., Frazão, B., Petersen, Bent, Peñaloza, F., Musacchia, F., Alexander, G. C., Osório, H., Winkelmann, I., Simakov, O., Rasmussen, Simon, Rahman, M. Z., Pisani, D., Vinther, J., Jarvis, E., Zhang, Guojie, Strugnell, J. M., Castro, L. F. C., Fedrigo, O., Patricio, M., Li, Q., Rocha, S., Antunes, A., Wu, Y., Ma, B., Sanges, R., Vinar, T., Blagoev, B., Sicheritz-Pontén, Thomas, Nielsen, Rasmus & Gilbert, M Thomas P, 2020, In : GigaScience. 9, 1, giz152.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    A dynamic charge-charge interaction modulates PP2A:B56 substrate recruitment

    Wang, X., Garvanska, Dimitriya Hristoforova, Nasa, I., Ueki, Yumi, Zhang, G., Kettenbach, A. N., Peti, W., Nilsson, Jakob & Page, R., 2020, In : eLife. 9, 19 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    A generic deep convolutional neural network framework for prediction of receptor–ligand interactions - NetPhosPan: application to kinase phosphorylation prediction

    Fenoy, E., Izarzugaza, J. M. G., Jurtz, V., Brunak, Søren & Nielsen, M., 2019, In : Bioinformatics. 35, 7, p. 1098-1107

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    A genome-wide association study identifies CDHR3 as a susceptibility locus for early childhood asthma with severe exacerbations

    Bønnelykke, K., Sleiman, P., Nielsen, K., Kreiner-Møller, E., Mercader, J. M., Belgrave, D., den Dekker, H. T., Husby, A., Sevelsted, A., Faura-Tellez, G., Paternoster, L., Flaaten, R., Mølgaard, A., Smart, D. E., Thomsen, P. F., Rasmussen, Morten Arendt, Bonàs-Guarch, S., Holst, C., Nohr, E. A., Yadav, R., March, M. E., Blicher, T. H., Lackie, P. M., Jaddoe, V. W. V., Simpson, A., Holloway, J. W., Duijts, L., Custovic, A., Davies, D. E., Torrents, D., Gupta, R., Hollegaard, M. V., Hougaard, D. M., Hakonarson, H. & Bisgaard, Hans, 2014, In : Nature Genetics. 46, p. 51-55 5 p.

    Research output: Contribution to journalLetterResearchpeer-review

  43. Published

    A genome-wide association study of men with symptoms of testicular dysgenesis syndrome and its network biology interpretation

    Dalgaard, M. D., Weinhold, N., Edsgärd, D., Silver, J. D., Pers, T. H., Nielsen, J. E., Jørgensen, N., Juul, Anders, Gerds, Thomas Alexander, Giwercman, A., Giwercman, Y. L., Cohn-Cedermark, G., Virtanen, H. E., Toppari, J., Daugaard, G., Jensen, T. S., Brunak, Søren, Rajpert-De Meyts, E., Skakkebæk, N. E., Leffers, H. & Gupta, R., 2012, In : Journal of Medical Genetics. 49, 1, p. 58-65 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    A genomic history of aboriginal Australia

    Malaspinas, A. S., Westaway, M. C., Muller, C. E., Sousa, V. C., Lao, O., Alves, I., Bergström, A., Athanasiadis, G., Cheng, J. Y., Crawford, J. E., Heupink, T. H., Macholdt, E., Peischl, S., Rasmussen, Simon, Schiffels, S., Subramanian, S., Wright, J. L., Albrechtsen, Anders, Barbieri, C., Dupanloup, I., Eriksson, A., Margaryan, Ashot, Moltke, Ida, Pugach, I., Korneliussen, Thorfinn Sand, Levkivskyi, I. P., Moreno Mayar, José Victor, Ni, S., Racimo, F., Sikora, Martin, Xue, Y., Aghakhanian, F. A., Brucato, N., Brunak, Søren, Campos, P., Clark, W., Ellingvåg, S., Fourmile, G., Gerbault, P., Injie, D., Koki, G., Leavesley, M., Logan, B., Lynch, A., Matisoo-Smith, E. A., McAllister, P. J., Mentzer, A. J., Metspalu, M., Migliano, A. B., Murgha, L., Phipps, M. E., Pomat, W., Reynolds, D., Ricaut, F., Siba, P., Thomas, M. G., Wales, T., Wall, C. M., Oppenheimer, S. J., Tyler-Smith, C., Durbin, R., Dortch, J., Manica, A., Schierup, M. H., Foley, R. A., Lahr, M. M., Bowern, C., Wall, J. D., Mailund, T., Stoneking, M., Nielsen, Rasmus, Sandhu, M. S., Excoffier, L., Lambert, D. M. & Willerslev, Eske, 2016, In : Nature. 538, 7624, p. 207-214 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    A knowledge base for the discovery of function, diagnostic potential and drug effects on cellular and extracellular miRNAs

    Russo, Francesco, Di Bella, S., Bonnici, V., Laganà, A., Rainaldi, G., Pellegrini, M., Pulvirenti, A., Giugno, R. & Ferro, A., 1 Jan 2014, In : BMC Genomics. 15, S4.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    A large size-selective DNA nanopore with sensing applications

    Thomsen, R. P., Malle, Mette Galsgaard, Okholm, A. H., Krishnan, S., Bohr, Søren Schmidt-Rasmussen, Sørensen, R. S., Ries, O., Vogel, S., Simmel, F. C., Hatzakis, Nikos & Kjems, J., 2019, In : Nature Communications. 10, 1

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    A large-cohort, longitudinal study determines pre-cancer disease routes across different cancer types

    Hjaltelin, Jessica Xin, Helleberg, M., Jensen, A. B., Brunak, Søren & Lundgren, Jens, 2019, In : Cancer Research. 79, 4, p. 864-872

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    A large-scale analysis of tissue-specific pathology and gene expression of human disease genes and complexes

    Hansen, K. L., Hansen, N. T., Karlberg, E. O., Eklund, A. C., Roque, F. S., Donahoe, P. K., Szallasi, Z., Jensen, T. S. & Brunak, Søren, 2008, In : Proceedings of the National Academy of Science of the United States of America. 105, 52, p. 20870-5 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    A lncRNA to repair DNA

    Lukas, Jiri & Altmeyer, M., Nov 2015, In : E M B O Reports. 16, 11, p. 1413-4 2 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  50. Published

    A minimal number of MELT repeats supports all functions of KNL1 in chromosome segregation

    Zhang, G., Lischetti, T. & Nilsson, Jakob, 20 Dec 2013, In : Journal of Cell Science. 127, p. 871-884

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    A new cellular stress response that triggers centriolar satellite reorganization and ciliogenesis

    Villumsen, B. H., Danielsen, J. R., Povlsen, L., Sylvestersen, K. B., Merdes, A., Beli, P., Yang, Y., Choudhary, Chuna Ram, Nielsen, Michael Lund, Mailand, Niels & Bekker-Jensen, Simon Holst, 11 Oct 2013, In : E M B O Journal. 32, 23, p. 3029-3040

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    A new method for discovering disease-specific MiRNA-target regulatory networks

    Baglioni, M., Russo, Francesco, Geraci, F., Rizzo, M., Rainaldi, G. & Pellegrini, M., 7 Apr 2015, In : PLoS ONE. 10, 4, e0122473.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    A new non-catalytic role for ubiquitin ligase RNF8 in unfolding higher-order chromatin structure

    Luijsterburg, M. S., Acs, K., Ackermann, L., Wiegant, W. W., Bekker-Jensen, Simon Holst, Larsen, D. H., Khanna, K. K., van Attikum, H., Mailand, Niels & Dantuma, N. P., 2012, In : E M B O Journal. 31, 11, p. 2511-27 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    A nondegenerate code of deleterious variants in mendelian Loci contributes to complex disease risk

    Blair, D. R., Lyttle, C. S., Mortensen, J. M., Bearden, C. F., Jensen, A. B., Khiabanian, H., Melamed, R., Rabadan, R., Bernstam, E. V., Brunak, Søren, Jensen, Lars Juhl, Nicolae, D., Shah, N. H., Grossman, R. L., Cox, N. J., White, K. P. & Rzhetsky, A., 26 Sep 2013, In : Cell. 155, 1, p. 70-80 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    A novel LC system embeds analytes in pre-formed gradients for rapid, ultra-robust proteomics

    Bache, N., Geyer, P. E., Bekker-Jensen, D. B., Hørning, O., Falkenby, L., Treit, P. V., Doll, S., Paron, I., Müller, J. B., Meier, F., Olsen, Jesper Velgaard, Vorm, O. & Mann, Matthias, 2018, In : Molecular and Cellular Proteomics. 17, 11, p. 2284-2296 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    A novel TPR-BEN domain interaction mediates PICH-BEND3 association

    Pitchai, G. P., Kaulich, M., Bizard, Anna Helene, Mesa, Pablo, Yao, Q., Sarlos, K., Streicher, W. W., Nigg, E. A., Montoya, Guillermo & Hickson, Ian David, 2017, In : Nucleic Acids Research. 19, 2, p. 11413–11424

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    A novel humanized mouse model of Huntington disease for preclinical development of therapeutics targeting mutant huntingtin alleles

    Southwell, A. L., Skotte, Niels Henning, Villanueva, Erika Bianca, Østergaard, M. E., Gu, X., Kordasiewicz, H. B., Kay, C., Cheung, D., Xie, Y., Waltl, S., Dal Cengio, L., Findlay-Black, H., Doty, C. N., Petoukhov, E., Iworima, D., Slama, R., Ooi, J., Pouladi, M. A., Yang, X. W., Swayze, E. E., Seth, P. P. & Hayden, M. R., 15 Mar 2017, In : Human Molecular Genetics. 26, 6, p. 1115-1132 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    A phospho-proteomic screen identifies substrates of the checkpoint kinase Chk1

    Blasius, M., Forment, J. V., Thakkar, N., Wagner, S. A., Choudhary, Chuna Ram & Jackson, S. P., 2011, In : Genome Biology (Online Edition). 12, 8, p. R78

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    A pilot project to generate affinity reagents to human proteins

    Uhlen, M., Gräslund, S. & Sundström, M., 1 Jan 2008, In : Nature Methods. 5, 10, p. 854-855 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    A proteomic study of the regulatory role for STAT-1 in cytokine-induced beta-cell death

    Rondas, D., Gudmundsdottir, V., D'Hertog, W., Crèvecoeur, I., Waelkens, E., Brunak, Søren, Mathieu, C. & Overbergh, L., Oct 2015, In : Proteomics - Clinical Applications. 9, 9-10, p. 938–952 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. Published

    A quantitative 14-3-3 interaction screen connects the nuclear exosome targeting complex to the DNA damage response

    Blasius, M., Wagner, S. A., Choudhary, Chuna Ram, Bartek, J. & Jackson, S. P., 4 Sep 2014, In : Genes & Development. 28, 18, p. 1977-1982 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. Published

    A quantitative Streptococcus pyogenes - human protein - protein interaction map reveals localization of opsonizing antibodies

    Happonen, L., Hauri, S., Svensson Birkedal, G., Karlsson, C., de Neergaard, T., Khakzad, H., Nordenfelt, P., Wikström, M., Wisniewska, M., Björck, L., Malmström, L. & Malmström, J., 2019, In : Nature Communications. 10, 15 p., 2727.

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. Published

    A redox-dependent dimerization switch regulates activity and tolerance for reactive oxygen species of barley seed glutathione peroxidase

    Navrot, N., Skjoldager, N., Bunkenborg, J., Svensson, B. & Hägglund, Per Mårten, 1 May 2015, In : Plant Physiology and Biochemistry. 90, p. 58-63 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  64. Published

    A role for small RNAs in DNA double-strand break repair

    Wei, W., Ba, Z., Wu, Y., Ma, Y., Qi, Y., Gao, M., Danielsen, J. M. R., Yang, Y., Amiard, S. & White, C. I., 30 Mar 2012, In : Cell. 149, 1, p. 101-112 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. Published

    A scored human protein-protein interaction network to catalyze genomic interpretation

    Li, T., Wernersson, R., Hansen, R. B., Horn, H., Mercer, J., Slodkowicz, G., Workman, C. T., Rigina, O., Rapacki, K., Stærfeldt, H. H., Brunak, Søren, Jensen, T. S. & Hansen, K. L., Jan 2017, In : Nature Methods. 14, 1, p. 61–64

    Research output: Contribution to journalLetterResearchpeer-review

  66. Published

    A secretory system for bacterial production of high-profile protein targets

    Kotzsch, A., Vernet, E., Hammarström, M., Berthelsen, J., Weigelt, J., Gräslund, S. & Sundström, M., 2011, In : Protein Science. 20, 3, p. 597-609 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  67. Published

    A side effect resource to capture phenotypic effects of drugs

    Kuhn, M., Campillos, M., Letunic, I., Jensen, Lars Juhl & Bork, P., 1 Jan 2010, In : Molecular Systems Biology. 6, p. 343

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. Published

    A spatially resolved proteomic atlas of human skin and its associated immune system

    Dyring-Andersen, Beatrice, Coscia, Fabian, Santos, A., Løvendorf, M. B., Sørensen, L. B. P., Niu, Lili, Andersen, J. L., Clark, R., Skov, L., Teunissen, M. B. & Mann, Matthias, 2019, In : Journal of Investigative Dermatology. 139, 9, suppl., p. S259 1 p.

    Research output: Contribution to journalConference abstract in journalResearch

  69. Published

    A spatially resolved proteomic atlas of psoriatic skin

    Dyring-Andersen, Beatrice, Lovendorf, M. B., Santos, A., Coscia, Fabian, Sørensen, L. B. P., Niu, Lili, Andersen, J. L., Teunissen, M. B., Skov, L. & Mann, Matthias, 2019, In : Journal of Investigative Dermatology. 139, 9, suppl., p. S260 1 p.

    Research output: Contribution to journalConference abstract in journalResearch

  70. Published

    A streamlined mass spectrometry-based proteomics workflow for large scale FFPE tissue analysis

    Coscia, Fabian, Doll, S., Bech, Jacob Mathias, Schweizer, L., Mund, Andreas, Lengyel, E., Lindebjerg, J., Madsen, G. I., Moreira, José & Mann, Matthias, 2020, In : Journal of Pathology. 251, p. 110-112

    Research output: Contribution to journalJournal articleResearchpeer-review

  71. Published

    A substrate-optimized electrophoretic mobility shift assay for ADAM12

    Kotzsch, A., Skovgaard, T., Buus, U., Andersen, S., Devkota, K. & Berthelsen, J., 1 May 2014, In : Analytical Biochemistry. 452, p. 34-42 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  72. Published

    A systematic study of site-specific GalNAc-type O-glycosylation modulating proprotein convertase processing

    Schjoldager, Katrine Ter-Borch Gram, Vester-Christensen, M. B., Goth, Christoffer Knak, Petersen, T. N., Brunak, Søren, Bennett, Eric Paul, Levery, S. B. & Clausen, Henrik, 18 Nov 2011, In : Journal of Biological Chemistry. 286, 46, p. 40122-32 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  73. Published

    A targeted proteomics toolkit for high-throughput absolute quantification of Escherichia coli proteins

    Batth, Tanveer Singh, Singh, P., Ramakrishnan, V. R., Sousa, M. M. L., Chan, L. J. G., Tran, H. M., Luning, E. G., Pan, E. H. Y., Vuu, K. M., Keasling, J. D., Adams, P. D. & Petzold, C. J., Nov 2014, In : Metabolic Engineering. 26, p. 48-56 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  74. Published

    A thermophilic ionic liquid-tolerant cellulase cocktail for the production of cellulosic biofuels

    Park, J. I., Steen, E. J., Burd, H., Evans, S. S., Redding-Johnson, A. M., Batth, Tanveer Singh, Benke, P. I., D'haeseleer, P., Sun, N., Sale, K. L., Keasling, J. D., Lee, T. S., Petzold, C. J., Mukhopadhyay, A., Singer, S. W., Simmons, B. A. & Gladden, J. M., 2012, In : PLoS ONE. 7, 5, p. e37010

    Research output: Contribution to journalJournal articleResearchpeer-review

  75. Published

    A two-step protein quality control pathway for a misfolded DJ-1 variant in fission yeast

    Mathiassen, S. G., Larsen, I. B., Poulsen, E. G., Madsen, C. T., Papaleo, Elena, Lindorff-Larsen, Kresten, Kragelund, Birthe Brandt, Nielsen, Michael Lund, Kriegenburg, F. & Hartmann-Petersen, Rasmus, 2015, In : The Journal of Biological Chemistry. 290, 34, p. 21141-21153 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  76. Published

    A variant in the G6PC2/ABCB11 locus is associated with increased fasting plasma glucose, increased basal hepatic glucose production and increased insulin release after oral and intravenous glucose loads

    Rose, C. S., Grarup, Niels, Krarup, N. T., Poulsen, P., Wegner, L., Nielsen, Trine, Banasik, Karina, Færch, Kristine, Andersen, G., Albrechtsen, Anders, Borch-Johnsen, K., Clausen, J. O., Jørgensen, T., Vaag, A., Pedersen, Oluf Borbye & Hansen, Torben, 2009, In : Diabetologia. 52, 10, p. 2122-2129 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  77. Published

    A versatile selection system for folding competent proteins using genetic complementation in a eukaryotic host.

    Lyngsø, C., Kjaerulff, S., Muller, S., Bratt, T., Mortensen, U. H. & Dal Degan, F., 2010, In : Protein Science. 19, 3, p. 579-592 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  78. Published

    ADAM12 is expressed in the tumour vasculature and mediates ectodomain shedding of several membrane-anchored endothelial proteins

    Frohlich, C., Klitgaard, M., Noer, J. B., Kotzsch, A., Nehammer, C., Kronqvist, P., Berthelsen, J., Blobel, C., Kveiborg, Marie, Albrechtsen, Reidar & Wewer, Ulla M., 15 May 2013, In : Biochemical Journal. 452, 1, p. 97-109 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  79. Published

    ADAM12-mediated shedding of basigin controls the subcellular localization and lactate transport of MCT4 and enhances collagen degradation in cancer cells: [Meeting Abstract}

    Albrechtsen, Reidar, Albrechtsen, Nicolai Jacob Wewer & Kveiborg, Marie, 2018, In : International Journal of Experimental Pathology. 99, 6, p. A25-A25

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  80. Published

    ALKBH4-dependent demethylation of actin regulates actomyosin dynamics

    Li, M., Shi, Y., Niu, Y., Wu, Y., Huang, C., Jin, K., Lv, Y., Danielsen, J. M. R., Yang, Y., Nilsen, A., Fusser, M., Olofsson, M., Klungland, A., Ding, Y., Dong, M., Fu, Y., He, C., Liu, B. & Xu, X., 14 May 2013, In : Nature Communications. 4, 13 p., 1832.

    Research output: Contribution to journalJournal articleResearchpeer-review

  81. Published

    ATR Prohibits Replication Catastrophe by Preventing Global Exhaustion of RPA

    Toledo Lazaro, Luis Ignacio, Altmeyer, M., Rask, M., Lukas, Claudia, Larsen, D. H., Povlsen, L. K., Bekker-Jensen, Simon Holst, Mailand, Niels, Bartek, J. & Lukas, Jiri, 21 Nov 2013, In : Cell. 155, 5, p. 1088-1103 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  82. Published

    ATR-Chk1-APC/C-dependent stabilization of Cdc7-ASK (Dbf4) kinase is required for DNA lesion bypass under replication stress

    Yamada, M., Watanabe, K., Mistrik, M., Vesela, E., Protivankova, I., Mailand, Niels, Lee, M. H., Masai, H., Lukas, Jiri & Bartek, J., 15 Nov 2013, In : Genes & Development. 27, 22, p. 2459-2472 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  83. Published

    Accurate Recycling of Parental Histones Reproduces the Histone Modification Landscape during DNA Replication

    Reveron-Gomez, Nazaret, González-Aguilera, C., Stewart-Morgan, Kathleen, Petryk, N., Flury, V., Graziano, Simona, Johansen, Jens Vilstrup, Jakobsen, J. S., Alabert, C. & Groth, Anja, 2018, In : Molecular Cell. 72, 2, p. 239-249 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  84. Published

    Accurate genotyping across variant classes and lengths using variant graphs

    Sibbesen, J. A., Maretty, L., Krogh, Anders, Petersen, Bent, Sibbesen, J. A., Liu, S., Have, C. T., Bork-Jensen, J., Guo, X., Hansen, Torben, Krogh, Anders, Sørensen, Thorkild I.A., Pedersen, Oluf Borbye, Wang, J. & Brunak, Søren, 2018, In : Nature Genetics. 50, p. 1054-1059 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  85. Published

    Accurate quantification of site-specific acetylation stoichiometry reveals the impact of sirtuin deacetylase CobB on the E. coli acetylome

    Weinert, B. T., Satpathy, S., Hansen, B. K., Lyon, D., Jensen, Lars Juhl & Choudhary, Chuna Ram, May 2017, In : Molecular and Cellular Proteomics. 16, p. 759-769

    Research output: Contribution to journalJournal articleResearchpeer-review

  86. Published

    Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli

    Weinert, B. T., Iesmantavicius, V., Wagner, S. A., Schölz, C., Gummesson, Bertil, Beli, P., Nyström, T. & Choudhary, Chuna Ram, 25 Jul 2013, In : Molecular Cell. 51, 2, p. 265-272 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  87. Published

    Acetylation dynamics and stoichiometry in Saccharomyces cerevisiae

    Weinert, B. T., Iesmantavicius, V., Moustafa, T., Schölz, C., Wagner, S. A., Magnes, C., Zechner, R. & Choudhary, Chuna Ram, 31 Jan 2014, In : Molecular Systems Biology. 10, 1, p. 716 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  88. Published

    Acetylation dynamics of human nuclear proteins during the ionizing radiation-induced DNA damage response

    Bennetzen, M., Andersen, J. S., Lasen, D. H., Dinant, C., Watanabe, S., Bartek, J. & Lukas, Jiri, 1 Jun 2013, In : Cell Cycle. 12, 11, p. 1688-1695 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  89. Published

    Acetylation of intrinsically disordered regions regulates phase separation

    Saito, M., Hess, D., Eglinger, J., Fritsch, A. W., Kreysing, M., Weinert, B. T., Choudhary, Chuna Ram & Matthias, P., Jan 2019, In : Nature Chemical Biology. 15, 1, p. 51-61

    Research output: Contribution to journalJournal articleResearchpeer-review

  90. Published

    Acetylation site specificities of lysine deacetylase inhibitors in human cells

    Schölz, C., Weinert, B. T., Wagner, S. A., Beli, P., Miyake, Y., Qi, J., Jensen, Lars Juhl, Streicher, W., McCarthy, A. R., Westwood, N. J., Lain, S., Cox, J., Matthias, P., Mann, M., Bradner, J. E. & Choudhary, Chuna Ram, 2015, In : Nature Biotechnology. 33, p. 415–423

    Research output: Contribution to journalJournal articleResearchpeer-review

  91. Published

    Acetyltransferases Gcn5 and PCAF regulate B cell development

    Beck, C., Daniel, J. & Oksenych, V., 2019, In : Scandinavian Journal of Immunology. 90, 6

    Research output: Contribution to journalConference abstract in journalResearch

  92. Published

    Acquisition of docetaxel resistance in breast cancer cells reveals upregulation of ABCB1 expression as a key mediator of resistance accompanied by discrete upregulation of other specific genes and pathways

    Hansen, S. N., Westergaard, David, Thomsen, M. B. H., Vistesen, M. V., Do, K. N., Fogh, L., Belling, Kirstine G, Wang, J., Yang, H., Gupta, R., Ditzel, H. J., Moreira, José, Brünner, Nils, Stenvang, Jan & Rasmussen, A. S., 2015, In : Tumor Biology. 36, 6, p. 4327-4338 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  93. Published

    Actin homolog MreB and RNA polymerase interact and are both required for chromosome segregation in Escherichia coli

    Kruse, Thomas, Blagoev, B., Løbner-Olesen, Anders, Wachi, M., Sasaki, K., Iwai, N., Mann, Matthias & Gerdes, K., 1 Jan 2006, In : Genes & Development. 20, 1, p. 113-124 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  94. Published

    Activation of the ATR kinase by the RPA-binding protein ETAA1

    Haahr, Peter Thorlund, Hoffmann, Saskia, Tollenaere, M. A. X., Ho, T., Toledo Lazaro, Luis Ignacio, Mann, Matthias, Bekker-Jensen, Simon Holst, Räschle, M. & Mailand, Niels, Nov 2016, In : Nature Cell Biology. 18, 11, p. 1196–1207

    Research output: Contribution to journalJournal articleResearchpeer-review

  95. Published

    Addicted to PAR? A closer look at PARP inhibitor sensitivity

    Altmeyer, M., 2012, In : Cell Cycle. 11, 21, p. 3916 1 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  96. Published

    Advances in characterizing ubiquitylation sites by mass spectrometry

    Sylvestersen, K. B., Young, C. & Nielsen, Michael Lund, 5 Jan 2013, In : Current Opinion in Chemical Biology. 17, 1, p. 49-58 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  97. Published

    Advancing cell biology through proteomics in space and time (PROSPECTS)

    Lamond, A. I., Uhlen, M., Horning, S., Makarov, A., Robinson, C. V., Serrano, L., Hartl, F. U., Baumeister, W., Werenskiold, A. K., Mann, Matthias, Andersen, J. S., Vorm, O., Linial, M. & Aebersold, R., 1 Mar 2012, In : Molecular & Cellular Proteomics. 11, 3, 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  98. Published

    Adverse outcome pathways: opportunities, limitations and open questions

    Leist, M., Ghallab, A., Graepel, R., Marchan, R., Hassan, R., Bennekou, S. H., Limonciel, A., Vinken, M., Schildknecht, S., Waldmann, T., Danen, E., van Ravenzwaay, B., Kamp, H., Gardner, I., Godoy, P., Bois, F. Y., Braeuning, A., Reif, R., Oesch, F., Drasdo, D., Höhme, S., Schwarz, M., Hartung, T., Braunbeck, T., Beltman, J., Vrieling, H., Sanz, F., Forsby, A., Gadaleta, D., Fisher, C., Kelm, J., Fluri, D., Ecker, G., Zdrazil, B., Terron, A., Jennings, P., van der Burg, B., Dooley, S., Meijer, A. H., Willighagen, E., Martens, M., Evelo, C., Mombelli, E., Taboureau, Olivier Thierry, Mantovani, A., Hardy, B., Koch, B., Escher, S., van Thriel, C., Cadenas, C., Kroese, D., van de Water, B. & Hengstler, J. G., Nov 2017, In : Archives of Toxicology. 91, 11, p. 3477-3505 29 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  99. Published

    Ago2 facilitates Rad51 recruitment and DNA double-strand break repair by homologous recombination

    Gao, M., Wei, W., Li, M. H., Wu, Y., Ba, Z., Jin, K., Li, M., Liao, Y., Adhikari, S., Chong, Z., Zhang, T., Guo, C., Tang, T., Zhu, B., Xu, X., Mailand, Niels, Yang, Y., Qi, Y. & Danielsen, J. M. R., May 2014, In : Cell Research. 24, 5, p. 532-41 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  100. Published

    Allosteric and orthosteric sites in CC chemokine receptor (CCR5), a chimeric receptor approach

    Thiele, S., Steen, A., Jensen, P. C., Mokrosinski, J., Frimurer, Thomas Michael & Rosenkilde, Mette, 2011, In : Journal of Biological Chemistry. 286, 43, p. 37543-54 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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