The NNF Center for Protein Research

  1. 2006
  2. Published

    Actin homolog MreB and RNA polymerase interact and are both required for chromosome segregation in Escherichia coli

    Kruse, Thomas, Blagoev, B., Løbner-Olesen, Anders, Wachi, M., Sasaki, K., Iwai, N., Mann, Matthias & Gerdes, K., 1 Jan 2006, In : Genes & Development. 20, 1, p. 113-124 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 2007
  4. Published

    Breast cancer cells with acquired antiestrogen resistance are sensitized to cisplatin-induced cell death

    Yde, C. W., Gyrd-Hansen, M., Lykkesfeldt, A. E., Issinger, O. & Stenvang, Jan, Jun 2007, In : Molecular Cancer Therapeutics. 6, 6, p. 1869-1876 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Design and characterization of dimeric ligands cross-linking two identical modulatory AMPA receptor sites

    Kaae, B. H., Harpsøe, Kasper, Sanz, A. C., Pickering, Darryl S, Sauerberg, P., Clausen, Rasmus Prætorius, Kastrup, Jette Sandholm Jensen, Liljefors, T. & Madsen, Ulf, 19 Aug 2007, In : American Chemical Society. Abstracts of Papers (at the National Meeting). 234

    Research output: Contribution to journalConference abstract in journalResearch

  6. 2008
  7. Published

    A large-scale analysis of tissue-specific pathology and gene expression of human disease genes and complexes

    Hansen, K. L., Hansen, N. T., Karlberg, E. O., Eklund, A. C., Roque, F. S., Donahoe, P. K., Szallasi, Z., Jensen, T. S. & Brunak, Søren, 2008, In : Proceedings of the National Academy of Science of the United States of America. 105, 52, p. 20870-5 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Circular reasoning rather than cyclic expression

    Jensen, Lars Juhl, de Lichtenberg, U., Jensen, T. S., Brunak, Søren & Bork, P., 2008, In : Genome Biology. 9, 6, p. 403

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Classification of Laser Induced Fluorescence Spectra from Normal and Malignant bladder tissues using Learning Vector Quantization Neural Network in Bladder Cancer Diagnosis

    Karemore, Gopal, Mascarenhas, K. K., Patil, C., V.K, U., Prabhu, V., Chowla, A., Nielsen, Mads & C, S., 2008, BIBE 2008: 8th. IEEE International Conference on Bioinformatics and BioEngineering, 8-10 October 2008. IEEE Communications Society, p. 1-6 6 p.

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

  10. Published

    Drug target identification using side-effect similarity

    Campillos, M., Kuhn, M., Gavin, A., Jensen, Lars Juhl & Bork, P., 2008, In : Science. 321, 5886, p. 263-6 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    HCLK2 is required for activity of the DNA damage response kinase ATR

    Rendtlew Danielsen, J. M., Larsen, D. H., Schou, K. B., Freire, R., Falck, J., Bartek, J. & Lukas, Jiri, 2008, In : Journal of Biological Chemistry. 284, 7, p. 4140-7 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Large-scale prediction of drug-target relationships

    Kuhn, M., Campillos, M., González, P., Jensen, Lars Juhl & Bork, P., 2008, In : F E B S Letters. 582, 8, p. 1283-90 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Linear motif atlas for phosphorylation-dependent signaling

    Miller, M. L., Jensen, Lars Juhl, Diella, F., Jørgensen, Claus Bøttcher, Tinti, M., Li, L., Hsiung, M., Parker, S. A., Bordeaux, J., Sicheritz-Ponten, T., Olhovsky, M., Pasculescu, A., Alexander, J., Knapp, S., Blom, N., Bork, P., Li, S., Cesareni, G., Pawson, T., Turk, B. E., Yaffe, M. B., Brunak, Søren & Linding, R., 2008, In : Science signaling. 1, 35, p. ra2

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Predicting biological networks from genomic data

    Harrington, E. D., Jensen, Lars Juhl & Bork, P., 2008, In : F E B S Letters. 582, 8, p. 1251-8 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    STRING 8--a global view on proteins and their functional interactions in 630 organisms

    Jensen, Lars Juhl, Kuhn, M., Stark, M., Chaffron, S., Creevey, C., Muller, J., Doerks, T., Julien, P., Roth, A., Simonovic, M., Bork, P. & von Mering, C., 2008, In : Nucleic Acids Research. 37, suppl 1, p. D412-D416 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Text mining for biology--the way forward: opinions from leading scientists

    Altman, R. B., Bergman, C. M., Blake, J., Blaschke, C., Cohen, A., Gannon, F., Grivell, L., Hahn, U., Hersh, W., Hirschman, L., Jensen, Lars Juhl, Krallinger, M., Mons, B., O'Donoghue, S. I., Peitsch, M. C., Rebholz-Schuhmann, D., Shatkay, H. & Valencia, A., 2008, In : Genome Biology (Online Edition). 9 Suppl 2, p. S7

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    A pilot project to generate affinity reagents to human proteins

    Uhlen, M., Gräslund, S. & Sundström, M., 1 Jan 2008, In : Nature Methods. 5, 10, p. 854-855 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Biochemistry. Not comparable, but complementary

    Jensen, Lars Juhl & Bork, P., 3 Oct 2008, In : Science (New York, N.Y.). 322, 5898, p. 56-7 2 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  19. 2009
  20. Published

    A variant in the G6PC2/ABCB11 locus is associated with increased fasting plasma glucose, increased basal hepatic glucose production and increased insulin release after oral and intravenous glucose loads

    Rose, C. S., Grarup, Niels, Krarup, N. T., Poulsen, P., Wegner, L., Nielsen, Trine, Banasik, Karina, Færch, Kristine, Andersen, G., Albrechtsen, Anders, Borch-Johnsen, K., Clausen, J. O., Jørgensen, T., Vaag, A., Pedersen, Oluf Borbye & Hansen, Torben, 2009, In : Diabetologia. 52, 10, p. 2122-2129 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Cell cycle regulation by feed-forward loops coupling transcription and phosphorylation

    Csikász-Nagy, A., Kapuy, O., Tóth, A., Pál, C., Jensen, Lars Juhl, Uhlmann, F., Tyson, J. J. & Novák, B., 2009, In : Molecular Systems Biology. 5, p. 236

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    G-allele of intronic rs10830963 in MTNR1B confers increased risk of impaired fasting glycemia and type 2 diabetes through an impaired glucose-stimulated insulin release: studies involving 19,605 Europeans

    Sparsø, T., Bonnefond, A., Andersson, E., Bouatia-Naji, N., Holmkvist, J., Wegner, L., Grarup, Niels, Gjesing, Anette Marianne Prior, Banasik, Karina, Cavalcanti-Proença, C., Marchand, M., Vaxillaire, M., Charpentier, G., Jarvelin, M., Tichet, J., Balkau, B., Marre, M., Lévy-Marchal, C., Faerch, K., Borch-Johnsen, K., Jørgensen, T., Madsbad, Sten, Poulsen, P., Vaag, A., Dina, C., Hansen, T., Pedersen, Oluf Borbye, Froguel, P., Sparsø, T., Bonnefond, A., Andersson, E., Bouatia-Naji, N., Holmkvist, J., Wegner, L., Grarup, N., Gjesing, A. P., Banasik, K., Cavalcanti-Proença, C., Marchand, M., Vaxillaire, M., Charpentier, G., Jarvelin, M., Tichet, J., Balkau, B., Marre, M., Lévy-Marchal, C., Faerch, K., Borch-Johnsen, K., Jørgensen, T., Madsbad, Sten, Poulsen, P., Vaag, A., Dina, C., Hansen, T., Pedersen, O. & Froguel, P., 2009, In : Diabetes. 58, 6, p. 1450-6 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Global analysis of the yeast osmotic stress response by quantitative proteomics

    Soufi, B., Kelstrup, C. D., Stoehr, G., Fröhlich, F., Walther, T. C. & Olsen, Jesper Velgaard, 2009, In : Molecular BioSystems. 5, 11, p. 1337-46 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Global effects of kinase inhibitors on signaling networks revealed by quantitative phosphoproteomics

    Pan, C., Olsen, Jesper Velgaard, Daub, H. & Mann, Matthias, 2009, In : Molecular and Cellular Proteomics. 8, 12, p. 2796-808 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    High-accuracy identification and bioinformatic analysis of in vivo protein phosphorylation sites in yeast

    Gnad, F., de Godoy, L. M. F., Cox, J., Neuhauser, N., Ren, S., Olsen, Jesper Velgaard & Mann, Matthias, 2009, In : Proteomics. 9, 20, p. 4642-4652 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Homologous and non-homologous sequence methods for assigning protein function

    Yeats, C., orengo, C., Veuthey, A. L., Boeckmann, B., Jensen, Lars Juhl, Valencia, A., Rausell, A. & Bork, P., 2009, Modern Genome Annotation: The BioSapien Network. Springer Publishing Company, p. 213-238

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  27. Published

    ImmunoGrid, an integrative environment for large-scale simulation of the immune system for vaccine discovery, design and optimization

    Pappalardo, F., Halling-Brown, M. D., Rapin, N., Zhang, P., Alemani, D., Emerson, A., Paci, P., Duroux, L. P., Pennisi, M., Palladini, A., Miotto, O., Churchill, D., Rossi, E., Shepherd, A. J., Moss, D. S., Castiglione, F., Bernaschi, M., Lefranc, M., Brunak, Søren, Motta, S., Lollini, P., Basford, K. E. & Brusic, V., 2009, In : Briefings in Bioinformatics. 10, 3, p. 330-40 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Lysine acetylation targets protein complexes and co-regulates major cellular functions

    Choudhary, Chuna Ram, Kumar, C., Gnad, F., Nielsen, Michael Lund, Rehman, M., Walther, T. C., Olsen, Jesper Velgaard & Mann, Matthias, 2009, In : Science. 325, 5942, p. 834-40 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Microblogging the ISMB: a new approach to conference reporting

    Saunders, N., Beltrão, P., Jurczak, D., Krause, R., Kuhn, M., Wu, S. & Jensen, Lars Juhl, 2009, In : PloS Computational Biology. 5, 1, p. e1000263

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Mislocalization of the MRN complex prevents ATR signaling during adenovirus infection

    Carson, C. T., Orazio, N. I., Lee, D. V., Suh, J., Bekker-Jensen, Simon Holst, Araujo, F. D., Lakdawala, S. S., Lilley, C. E., Bartek, J., Lukas, Jiri & Weitzman, M. D., 2009, In : EMBO Journal. 28, 6, p. 652-62 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Mislocalized activation of oncogenic RTKs switches downstream signaling outcomes

    Choudhary, Chuna Ram, Olsen, Jesper Velgaard, Brandts, C., Cox, J., Reddy, P. N. G., Böhmer, F. D., Gerke, V., Schmidt-Arras, D., Berdel, W. E., Müller-Tidow, C., Mann, Matthias & Serve, H., 2009, In : Molecular Cell. 36, 2, p. 326-39 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Protein-protein interactions: analysis and prediction

    Frishman, D., Albert, M., Blankenburg, H., Bork, P., Harrington, E. D., Hermjakob, H., Jensen, Lars Juhl, Juan, D. A., Pagel, P., Schachter, V. & Valencia, A., 2009, Modern Genome Annotation: The BioSapien Network. Springer Publishing Company, p. 353-410 (Modern Genome Annotation: The BioSapiens network).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  33. Published

    Quantifying environmental adaptation of metabolic pathways in metagenomics

    Gianoulis, T. A., Raes, J., Patel, P. V., Bjornson, R., Korbel, J. O., Letunic, I., Yamada, T., Paccanaro, A., Snyder, M., Bork, P., Gerstein, M. B. & Jensen, Lars Juhl, 2009, In : Proceedings of the National Academy of Science of the United States of America. 106, 5, p. 1374-9 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Reflect: augmented browsing for the life scientist

    Pafilis, E., O'Donoghue, S. I., Jensen, Lars Juhl, Horn, H., Kuhn, M., Brown, N. P. & Schneider, R., 2009, In : Nature Biotechnology. 27, 6, p. 508-10 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    The binding of NCAM to FGFR1 induces a specific cellular response mediated by receptor trafficking

    Francavilla, C., Cattaneo, P., Berezin, V., Bock, E., Ami, D., de Marco, A., Christofori, G. & Cavallaro, U., 2009, In : Journal of Cell Biology. 187, 7, p. 1101-16 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published
  37. Published

    The type 2 diabetes associated minor allele of rs2237895 KCNQ1 associates with reduced insulin release following an oral glucose load

    Holmkvist, J., Banasik, K., Andersen, G., Unoki, H., Jensen, T. S., Pisinger, Charlotta Holm, Borch-Johnsen, K., Sandbaek, A., Lauritzen, T., Brunak, Søren, Maeda, S., Hansen, T. & Pedersen, Oluf Borbye, 2009, In : PLoS ONE. 4, 6, p. e5872

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Transfection of small RNAs globally perturbs gene regulation by endogenous microRNAs

    Khan, A. A., Betel, D., Miller, M. L., Sander, C., Leslie, C. S. & Marks, D. S., 2009, In : Nature Biotechnology. 27, 6, p. 549-55 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Crystal structure of CbpF, a bifunctional choline-binding protein and autolysis regulator from Streptococcus pneumoniae

    Molina, Rafael, Gonzalez, Ana Valeria, Stelter, M., Pérez-Dorado, I., Kahn, R., Morales, M., Moscoso, M., Campuzano, S., Campillo, N. E., Mobashery, S., García, J. L., García, P. & Hermoso, J. A., Mar 2009, In : EMBO Reports. 10, 3, p. 246-51 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Characterization of gadolinium complexes for SAD phasing in macromolecular crystallography: application to CbpF

    Molina, Rafael, Stelter, M., Kahn, R. & Hermoso, J. A., Aug 2009, In : Acta crystallographica. Section D, Biological crystallography. 65, Pt 8, p. 823-31 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Role of the AMPKgamma3 isoform in hypoxia-stimulated glucose transport in glycolytic skeletal muscle

    Deshmukh, Atul Shahaji, Glund, S., Tom, R. Z. & Zierath, Juleen R, Dec 2009, In : American Journal of Physiology: Endocrinology and Metabolism. 297, 6, p. E1388-94

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Novel selective thiazoleacetic acids as CRTH2 antagonists developed from in silico derived hits. Part 1

    Rist, O., Grimstrup, M., Receveur, J., Frimurer, Thomas Michael, Ulven, Trond, Kostenis, E. & Högberg, T., 4 Dec 2009, In : Bioorganic & Medicinal Chemistry Letters. 20, 3, p. 1177-1180 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. 2010
  44. Published

    A versatile selection system for folding competent proteins using genetic complementation in a eukaryotic host.

    Lyngsø, C., Kjaerulff, S., Muller, S., Bratt, T., Mortensen, U. H. & Dal Degan, F., 2010, In : Protein Science. 19, 3, p. 579-592 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Cyclebase.org: version 2.0, an updated comprehensive, multi-species repository of cell cycle experiments and derived analysis results

    Gauthier, N. P., Jensen, Lars Juhl, Wernersson, R., Brunak, Søren & Jensen, T. S., 2010, In : Nucleic Acids Research. 38, Database issue, p. D699-702

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Dissecting spatio-temporal protein networks driving human heart development and related disorders

    Hansen, K. L., Møllgård, Kjeld, Greenway, S., Wakimoto, H., Gorham, J. M., Workman, C. T., Bendsen, E., Hansen, N. T., Rigina, O., Roque, F. S., Wiese, C., Christoffels, V. M., Roberts, A. E., Smoot, L. B., Pu, W. T., Donahoe, P. K., Tommerup, Niels, Brunak, Søren, Seidman, C. E., Seidman, J. G. & Larsen, Lars Allan, 2010, In : Molecular Systems Biology. 6, p. 381

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Ezrin mediates c-Myc actions in prostate cancer cell invasion

    Chuan, Y. C., Iglesias Gato, Diego, Fernandez-Perez, L., Cedazo-Minguez, A., Pang, S., Norstedt, G., Pousette, A. & Flores-Morales, A., 2010, In : Oncogene. 29, 10, p. 1531-42 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Prediction of human targets for viral-encoded microRNAs by thermodynamics and empirical constraints

    Laganá, A., Forte, S., Russo, Francesco, Giugno, R., Pulvirenti, A. & Ferro, A., 2010, In : Journal of RNAi and Gene Silencing.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis

    Olsen, Jesper Velgaard, Vermeulen, M., Santamaria, A., Kumar, C., Miller, M. L., Jensen, Lars Juhl, Gnad, F., Cox, J., Jensen, T. S., Nigg, E. A., Brunak, Søren & Mann, Matthias, 2010, In : Science Signaling. 3, 104, p. ra3 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    STITCH 2: an interaction network database for small molecules and proteins

    Kuhn, M., Szklarczyk, D., Franceschini, A., Campillos, M., von Mering, C., Jensen, Lars Juhl, Beyer, A. & Bork, P., 2010, In : Nucleic Acids Research. 38, Database issue, p. D552-6

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Structural basis for KV7.1/KCNEx interactions in the IKs channel complex

    Lundby, Alicia, Tseng, G. & Schmitt, Nicole, 2010, In : Heart Rhythm. 7, 5, p. 708-713

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Understanding the proteome - the missing link for successful drug discovery

    Sundström, M., 2010, In : Bioforum Europe. 1-2, p. 12-13

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    A side effect resource to capture phenotypic effects of drugs

    Kuhn, M., Campillos, M., Letunic, I., Jensen, Lars Juhl & Bork, P., 1 Jan 2010, In : Molecular Systems Biology. 6, p. 343

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Drug-induced regulation of target expression

    Iskar, M., Campillos, M., Kuhn, M., Jensen, Lars Juhl, van Noort, V. & Bork, P., 1 Jan 2010, In : PloS Computational Biology. 6, 9

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    Early detection of response to experimental chemotherapeutic Top216 with [18F]FLT and [18F]FDG PET in human ovary cancer xenografts in mice

    Wessel, Mette Munk, Erichsen, K. D., Björkling, Fredrik, Madsen, J., Jensen, P. B., Højgaard, Liselotte, Sehested, M. & Kjær, Andreas, 1 Jan 2010, In : P L o S One. 5, 9, p. e12965

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    High-resolution transcription atlas of the mitotic cell cycle in budding yeast

    Granovskaia, M. V., Jensen, Lars Juhl, Ritchie, M. E., Toedling, J., Ning, Y., Bork, P., Huber, W. & Steinmetz, L. M., 1 Jan 2010, In : Genome Biology (Online Edition). 11, 3, p. R24

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    Yeast expression proteomics by high-resolution mass spectrometry

    Walther, T. C., Olsen, Jesper Velgaard & Mann, Matthias, 1 Jan 2010, In : Methods in Enzymology. 470, p. 259-80 22 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    eggNOG v2.0: extending the evolutionary genealogy of genes with enhanced non-supervised orthologous groups, species and functional annotations

    Muller, J., Szklarczyk, D., Julien, P., Letunic, I., Roth, A., Kuhn, M., Powell, S., von Mering, C., Doerks, T., Jensen, Lars Juhl & Bork, P., 1 Jan 2010, In : Nucleic Acids Symposium Series. 38, Database issue, p. D190-5

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    Novel selective thiazoleacetic acids as CRTH2 antagonists developed from in silico derived hits. Part 2

    Grimstrup, M., Rist, Ø., Receveur, J., Frimurer, Thomas Michael, Ulven, Trond, Mathiesen, Jesper M., Kostenis, E. & Högberg, T., 1 Feb 2010, In : Bioorganic & Medicinal Chemistry Letters. 20, 3, p. 1181-1185 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    Ancient human genome sequence of an extinct Palaeo-Eskimo

    Rasmussen, M., Li, Y., Lindgreen, Stinus, Pedersen, J. S., Albrechtsen, Anders, Moltke, Ida, Metspalu, M., Metspalu, E., Kivisild, T., Gupta, R., Bertalan, M., Nielsen, K., Gilbert, M Thomas P, Wang, Y., Raghavan, M., Campos, P., Kamp, Hanne Louise Munkholm, Wilson, A. S., Gledhill, A., Tridico, S., Bunce, M., Lorenzen, Eline, Binladen, J. K. M. A., Guo, X., Zhao, J., Zhang, X., Zhang, H., Li, Z., Chen, M., Orlando, L. A. A., Kristiansen, Karsten, Bak, Mads, Tommerup, Niels, Bendixen, C., Pierre, T. L., Grønnow, B., Meldgaard, Morten, Andreasen, C., Fedorova, S. A., Osipova, L. P., Higham, T. F. G., Ramsey, C. B., Hansen, T. V. O., Nielsen, Finn Cilius, Crawford, M. H., Brunak, Søren, Sicheritz-Pontén, T., Villems, R., Nielsen, Rasmus, Krogh, Anders, Wang, J. & Willerslev, Eske, 11 Feb 2010, In : Nature. 463, 7282, p. 757-762 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. Published

    Evolution and regulation of cellular periodic processes: a role for paralogues

    Trachana, K., Jensen, Lars Juhl & Bork, P., 1 Mar 2010, In : E M B O Reports. 11, 3, p. 233-8 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. Published

    Exploration of SAR features by modifications of thiazoleacetic acids as CRTH2 antagonists

    Grimstrup, M., Receveur, J. M., Rist, Ø., Frimurer, Thomas Michael, Nielsen, P. A., Mathiesen, Jesper M. & Högberg, T., 1 Mar 2010, In : Bioorganic and Medicinal Chemistry Letters. 20, 5, p. 1638-1641 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. Published

    Interdependence of AMPK and SIRT1 for metabolic adaptation to fasting and exercise in skeletal muscle

    Cantó, C., Jiang, L. Q., Deshmukh, Atul Shahaji, Mataki, C., Coste, A., Lagouge, M., Zierath, Juleen R & Auwerx, J., 3 Mar 2010, In : Cell Metabolism. 11, 3, p. 213-9 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  64. Published

    4.0-A resolution cryo-EM structure of the mammalian chaperonin TRiC/CCT reveals its unique subunit arrangement

    Cong, Y., Baker, M. L., Jakana, J., Woolford, D., Miller, E. J., Reissmann, S., Kumar, R. N., Redding-Johanson, A. M., Batth, Tanveer Singh, Mukhopadhyay, A., Ludtke, S. J., Frydman, J. & Chiu, W., 16 Mar 2010, In : Proceedings of the National Academy of Sciences of the United States of America. 107, 11, p. 4967-72 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. Published

    Suppression of water as a nucleophile in Candida antarctica lipase B catalysis

    Larsen, M. W., Zielinska, D. F., Martinelle, M., Hidalgo, A., Jensen, Lars Juhl, Bornscheuer, U. T. & Hult, K., 12 Apr 2010, In : ChemBioChem. 11, 6, p. 796-801 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  66. Published

    The shape of the DNA minor groove directs binding by the DNA-bending protein Fis

    Stella, Stefano, Cascio, D. & Johnson, R. C., 15 Apr 2010, In : Genes and Development. 24, 8, p. 814-826 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  67. Published

    Ontologies in quantitative biology: a basis for comparison, integration, and discovery

    Jensen, Lars Juhl & Bork, P., 1 May 2010, In : PLoS Biology. 8, 5, p. e1000374

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. Published

    Nitric oxide increases cyclic GMP levels, AMP-activated protein kinase (AMPK)alpha1-specific activity and glucose transport in human skeletal muscle

    Deshmukh, Atul Shahaji, Long, Y. C., de Castro Barbosa, T., Karlsson, H. K. R., Glund, S., Zavadoski, W. J., Gibbs, E. M., Koistinen, H. A., Wallberg-Henriksson, H. & Zierath, Juleen R, Jun 2010, In : Diabetologia. 53, 6, p. 1142-50 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. Published

    Crystallization and preliminary crystallographic analysis of the catalytic module of endolysin from Cp-7, a phage infecting Streptococcus pneumoniae

    Silva-Martin, N., Molina, Rafael, Angulo, I., Mancheño, J. M., García, P. & Hermoso, J. A., 1 Jun 2010, In : Acta Crystallographica Section F: Structural Biology Communications. 66, Pt 6, p. 670-3 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  70. Published

    Decoding signalling networks by mass spectrometry-based proteomics

    Choudhary, Chuna Ram & Mann, Matthias, 1 Jun 2010, In : Nature Reviews. Molecular Cell Biology. 11, 6, p. 427-39 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  71. Published

    Protein annotation in the era of personal genomics

    Blicher, T., Gupta, R., Wesolowska, A., Jensen, Lars Juhl & Brunak, Søren, 1 Jun 2010, In : Current Opinion in Structural Biology. 20, 3, p. 335-41 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  72. Published

    The phosphoproteome of toll-like receptor-activated macrophages

    Weintz, G., Olsen, Jesper Velgaard, Frühauf, K., Niedzielska, M., Amit, I., Jantsch, J., Mages, J., Frech, C., Dölken, L., Mann, M. & Lang, R., 8 Jun 2010, In : Molecular Systems Biology. 6, p. 371

    Research output: Contribution to journalJournal articleResearchpeer-review

  73. Published

    Quantitative phosphoproteomics dissection of 7TM receptor signaling using full and biased agonists

    Christensen, G. L., Kelstrup, C., Lyngsø, C., Sarwar, U., Bøgebo, R., Sheikh, S. P., Gammeltoft, S., Olsen, Jesper Velgaard & Hansen, J. L., Jul 2010, In : Molecular and Cellular Proteomics. 9, 7, p. 1540-53 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  74. Published

    Reflect: a practical approach to web semantics

    O'Donoghue, S. I., Horn, H., Pafilisa, E., Haag, S., Kuhn, M., Satagopam, V. P., Schneider, R. & Jensen, Lars Juhl, Jul 2010, In : Journal of Web Semantics. 8, 2-3, p. 182-189

    Research output: Contribution to journalJournal articleResearchpeer-review

  75. Published

    Predicting post-translational lysine acetylation using support vector machines

    Gnad, F., Ren, S., Choudhary, Chuna Ram, Cox, J. & Mann, M., 1 Jul 2010, In : Bioinformatics. 26, 13, p. 1666-8 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  76. Published

    Biophysical characterization of the fluorescent protein voltage probe VSFP2.3 based on the voltage-sensing domain of Ci-VSP

    Lundby, Alicia, Akemann, W. & Knöpfel, T., 6 Aug 2010, In : European Biophysics Journal. 39, 12, p. 1625-1635 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  77. Published

    Variability in the incidence of miRNAs and genes in fragile sites and the role of repeats and CpG islands in the distribution of genetic material

    Laganà, A., Russo, Francesco, Sismeiro, C., Giugno, R., Pulvirenti, A. & Ferro, A., 11 Aug 2010, In : PLoS ONE. 5, 6, e11166.

    Research output: Contribution to journalJournal articleResearchpeer-review

  78. Published

    Incentive and entrenchment effects in European ownership

    Bennedsen, Morten & Nielsen, K. M., Sep 2010, In : Journal of Banking & Finance. 34, 9, p. 2212-2229

    Research output: Contribution to journalJournal articleResearchpeer-review

  79. Published

    Quantitative interaction proteomics and genome-wide profiling of epigenetic histone marks and their readers

    Vermeulen, M., Eberl, H. C., Matarese, F., Marks, H., Denissov, S., Butter, F., Lee, K. K., Olsen, Jesper Velgaard, Hyman, A. A., Stunnenberg, H. G. & Mann, M., 17 Sep 2010, In : Cell. 142, 6, p. 967-80 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  80. Published

    Bioinformatics training: a review of challenges, actions and support requirements

    Schneider, M. V., Watson, J., Attwood, T., Rother, K., Budd, A., McDowall, J., Via, A., Fernandes, P., Nyronen, T., Blicher, T., Jones, P., Blatter, M., De Las Rivas, J., Judge, D. P., van der Gool, W. & Brooksbank, C., Nov 2010, In : Briefings in Bioinformatics. II, 6, p. 544-51 8 p.

    Research output: Contribution to journalReviewResearchpeer-review

  81. Published

    Dipeptidyl peptidase-4 inhibitors administered in combination with metformin result in an additive increase in the plasma concentration of active GLP-1

    Migoya, E. M., Bergeron, R., Miller, J. L., Snyder, R. N. K., Tanen, M., Hilliard, D., Weiss, B., Larson, P., Gutierrez, M., Jiang, G., Liu, F., Pryor, K. A., Yao, J., Zhu, L., Holst, Jens Juul, Deacon, Carolyn F., Herman, G., Thornberry, N., Amatruda, J., Williams-Herman, D., Wagner, J. A. & SinhaRoy, R., 1 Dec 2010, In : Clinical Pharmacology and Therapeutics. 88, 6, p. 801-8 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  82. Published

    Feasibility of large-scale phosphoproteomics with higher energy collisional dissociation fragmentation

    Nagaraj, N., D'Souza, R. C. J., Cox, J., Olsen, Jesper Velgaard & Mann, M., 3 Dec 2010, In : Journal of Proteome Research. 9, 12, p. 6786-94 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  83. Published

    Assembly and function of DNA double-strand break repair foci in mammalian cells

    Bekker-Jensen, Simon Holst & Mailand, Niels, 10 Dec 2010, In : D N A Repair. 9, 12, p. 1219-28 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  84. 2011
  85. Published

    A phospho-proteomic screen identifies substrates of the checkpoint kinase Chk1

    Blasius, M., Forment, J. V., Thakkar, N., Wagner, S. A., Choudhary, Chuna Ram & Jackson, S. P., 2011, In : Genome Biology (Online Edition). 12, 8, p. R78

    Research output: Contribution to journalJournal articleResearchpeer-review

  86. Published

    A secretory system for bacterial production of high-profile protein targets

    Kotzsch, A., Vernet, E., Hammarström, M., Berthelsen, J., Weigelt, J., Gräslund, S. & Sundström, M., 2011, In : Protein Science. 20, 3, p. 597-609 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  87. Published

    Allosteric and orthosteric sites in CC chemokine receptor (CCR5), a chimeric receptor approach

    Thiele, S., Steen, A., Jensen, P. C., Mokrosinski, J., Frimurer, Thomas Michael & Rosenkilde, Mette, 2011, In : Journal of Biological Chemistry. 286, 43, p. 37543-54 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  88. Published

    An Aboriginal Australian genome reveals separate human dispersals into Asia

    Rasmussen, M., Guo, X., Wang, Y., Lohmueller, K. E., Rasmussen, Simon, Albrechtsen, Anders, Skotte, L., Lindgreen, Stinus, Metspalu, M., Jombart, T., Kivisild, T., Zhai, W., Eriksson, A., Manica, A., Orlando, L., De La Vega, F. M., Tridico, S., Metspalu, E., Nielsen, K., Avila Arcos, M. D. C., Moreno Mayar, José Victor, Muller, C., Dortch, J., Gilbert, M Thomas P, Lund, O., Wesolowska, A., Karmin, M., Weinert, L. A., Wang, B., Li, J., Tai, S., Xiao, F., Hanihara, T., van Driem, G., Jha, A. R., Ricaut, F., de Knijff, P., Migliano, A. B., Gallego Romero, I., Kristiansen, Karsten, Lambert, D. M., Brunak, Søren, Forster, P., Brinkmann, B., Nehlich, O., Bunce, M., Richards, M., Gupta, R., Bustamante, C. D., Krogh, Anders, Foley, R. A., Lahr, M. M., Balloux, F., Sicheritz-Pontén, T., Villems, R., Nielsen, Rasmus, Wang, J. & Willerslev, Eske, 2011, In : Science. 334, 6052, p. 94-98 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  89. Published

    An anatomically oriented breast coordinate system for mammogram analysis

    Brandt, S., Karemore, Gopal, Karssemeijer, N. & Nielsen, Mads, 2011, In : I E E E Transactions on Medical Imaging. 30, 10, p. 1841-1851 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  90. Published

    BioStar: an online question & answer resource for the bioinformatics community

    Parnell, L. D., Lindenbaum, P., Shameer, K., Dall'Olio, G. M., Swan, D. C., Jensen, Lars Juhl, Cockell, S. J., Pedersen, B. S., Mangan, M. E., Miller, C. A. & Albert, I., 2011, In : P L o S Computational Biology (Online). 7, 10, p. e1002216

    Research output: Contribution to journalJournal articleResearchpeer-review

  91. Published

    Cdc20 control of cell fate during prolonged mitotic arrest: do Cdc20 protein levels affect cell fate in response to antimitotic compounds?

    Nilsson, Jakob, 2011, In : BioEssays. 33, 12, p. 903-9 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  92. Published

    Enterotypes of the human gut microbiome: [Plus]Corrigendum [Plus]Addendum

    Arumugam, Mani, Raes, J., Pelletier, E., Le Paslier, D., Yamada, T., Mende, D. R., Fernandes, G. R., Tap, J., Bruls, T., Batto, J., dos Santos, M. B. Q., Borruel, N., Casellas, F., Fernandez, L., Gautier, L., Hansen, Torben, Hattori, M., Hayashi, T., Kleerebezem, M., Kurokawa, K., Leclerc, M., Levenez, F., Manichanh, C., Nielsen, H. B., Nielsen, Trine, Pons, N., Poulain, J., Qin, J., Sicheritz-Ponten, T., Tims, S., Torrents, D., Ugarte, E., Zoetendal, E. G., Wang, J., Guarner, F., Pedersen, Oluf Borbye, de Vos, W. M., Brunak, Søren, Doré, J., Antolín, M., Artiguenave, F., Blottiere, H. M., Almeida, M., Brechot, C., Cara, C., Chervaux, C., Cultrone, A., Delorme, C., Denariaz, G., Kristiansen, Karsten & MetaHIT Consortium, M. C., 2011, In : Nature. 473, 7346, p. 174-180 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  93. Published

    Global phosphoproteome profiling reveals unanticipated networks responsive to cisplatin treatment of embryonic stem cells

    Pines, A., Kelstrup, C. D., Vrouwe, M. G., Puigvert, J. C., Typas, D., Misovic, B., de Groot, A., von Stechow, L., van de Water, B., Danen, E. H. J., Vrieling, H., Mullenders, L. H. F. & Olsen, Jesper Velgaard, 2011, In : Molecular and Cellular Biology. 31, 24, p. 4964-77 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  94. Published

    Huntingtin-interacting protein 14 is a type 1 diabetes candidate protein regulating insulin secretion and beta-cell apoptosis

    Berchtold, L. A., Størling, Z. M., Ortis, F., Lage, K., Bang-Berthelsen, C., Bergholdt, R., Hald, J., Brorsson, C. A., Eizirik, D. L., Pociot, Flemming, Brunak, Søren & Størling, Joachim, 2011, In : PNAS Early Edition. 108, 37, p. E681-8

    Research output: Contribution to journalJournal articleResearchpeer-review

  95. Published

    Identification of animal species in skin clothing from museum collections

    Schmidt, A. L., Gilbert, M Thomas P, Cappellini, Enrico & Olsen, Jesper Velgaard, 2011. 8 p.

    Research output: Contribution to conferencePaperResearchpeer-review

  96. Published

    Inhibitor of apoptosis (IAP) proteins in regulation of inflammation and innate immunity

    Damgaard, R. B. & Gyrd-Hansen, M., 2011, In : Discovery Medicine. 11, 58, p. 221-31 11 p.

    Research output: Contribution to journalReviewResearchpeer-review

  97. Published

    Phosphorylation of the yeast γ-tubulin Tub4 regulates microtubule function

    Lin, T., Gombos, L., Neuner, A., Sebastian, D., Olsen, Jesper Velgaard, Hrle, A., Benda, C. & Schiebel, E., 2011, In : P L o S One. 6, 5, p. e19700

    Research output: Contribution to journalJournal articleResearchpeer-review

  98. Published

    Pre-Clovis mastodon hunting 13,800 years ago at the Manis site, Washington

    Waters, M. R., Stafford jr., T., McDonald, H. G., Gustafson, C., Rasmussen, M., Cappellini, Enrico, Olsen, Jesper Velgaard, Szklarczyk, D. M., Jensen, Lars Juhl, Gilbert, M Thomas P & Willerslev, Eske, 2011, In : Science. 334, 6054, p. 351-353 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  99. Published

    Predictive mutagenesis of ligation-independent cloning (LIC) vectors for protein expression and site-specific chemical conjugation

    Vernet, E., Sauer, J., Andersen, P. A., Jensen, Knud Jørgen & Voldborg, B. G. R., 2011, In : Analytical Biochemistry. 414, 2, p. 312-314 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  100. Published

    Protein interaction-based genome-wide analysis of incident coronary heart disease

    Jensen, Majken Karoline, Pers, Tune H, Dworzynski, P., Girman, C. J., Brunak, Søren & Rimm, E. B., 2011, In : Circulation: Cardiovascular Genetics. 4, 5, p. 549-56 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  101. Published

    Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation

    Weinert, B. T., Wagner, S. A., Horn, H., Henriksen, P., Liu, W. R., Olsen, Jesper Velgaard, Jensen, Lars Juhl & Choudhary, Chuna Ram, 2011, In : Science Signaling. 4, 183, p. ra48

    Research output: Contribution to journalJournal articleResearchpeer-review

  102. Published

    Screening of genetic parameters for soluble protein expression in Escherichia coli

    Vernet, E., Kotzsch, A., Voldborg, B. & Sundström, M., 2011, In : Protein Expression and Purification. 77, 1, p. 104-11 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  103. Published

    SignalP 4.0: discriminating signal peptides from transmembrane regions

    Petersen, T. N., Brunak, Søren, von Heijne, G. & Nielsen, H., 2011, In : Nature Methods. 8, 10, p. 785-6 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  104. Published

    Specific CLK inhibitors from a novel chemotype for regulation of alternative splicing

    Fedorov, O., Huber, K., Eisenreich, A., Filippakopoulos, P., King, O., Bullock, A. N., Szklarczyk, D., Jensen, Lars Juhl, Fabbro, D., Trappe, J., Rauch, U., Bracher, F. & Knapp, S., 2011, In : Chemistry & Biology. 18, 1, p. 67-76 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  105. Published

    Structural basis for c-KIT inhibition by the suppressor of cytokine signaling 6 (SOCS6) ubiquitin ligase

    Zadjali, F., Pike, A. C. W., Vesterlund, M., Sun, J., Wu, C., Li, S. S. C., Rönnstrand, L., Knapp, S., Bullock, A. N. & Flores Morales, A., 2011, In : Journal of Biological Chemistry. 286, 1, p. 480-90 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  106. Published

    System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation

    Rigbolt, K. T. G., Prokhorova, T., Akimov, V., Løkkegaard, Jeanette, Johansen, P. T., Kratchmarova, I., Kassem, M. S. E., Mann, Matthias, Olsen, Jesper Velgaard & Blagoev, B., 2011, In : Science Signaling. 4, 164, p. rs3

    Research output: Contribution to journalJournal articleResearchpeer-review

  107. Published

    The STRING database in 2011: functional interaction networks of proteins, globally integrated and scored

    Szklarczyk, D., Franceschini, A., Kuhn, M., Simonovic, M., Roth, A., Minguez, P., Doerks, T., Stark, M., Muller, J., Bork, P., Jensen, Lars Juhl & von Mering, C., 2011, In : Nucleic Acids Research. 39, Database issue, p. D561-8

    Research output: Contribution to journalJournal articleResearchpeer-review

  108. Published

    The rise and fall of supervised machine learning techniques

    Jensen, Lars Juhl & Bateman, A., 2011, In : Bioinformatics (Online). 27, 24, p. 3331-2 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  109. Published

    The ubiquitin-selective segregase VCP/p97 orchestrates the response to DNA double-strand breaks

    Meerang, M., Ritz, D., Paliwal, S., Garajova, Z., Bosshard, M., Mailand, Niels, Janscak, P., Hübscher, U., Meyer, H. & Ramadan, K., 2011, In : Nature Cell Biology. 13, 11, p. 1376-82 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  110. Published

    Toward molecular trait-based ecology through integration of biogeochemical, geographical and metagenomic data

    Raes, J., Letunic, I., Yamada, T., Jensen, Lars Juhl & Bork, P., 2011, In : Molecular Systems Biology. 7, p. 473

    Research output: Contribution to journalJournal articleResearchpeer-review

  111. Published

    Towards a rigorous network of protein-protein interactions of the model sulfate reducer Desulfovibrio vulgaris Hildenborough

    Chhabra, S. R., Joachimiak, M. P., Petzold, C. J., Zane, G. M., Price, M. N., Reveco, S. A., Fok, V., Johanson, A. R., Batth, Tanveer Singh, Singer, M., Chandonia, J., Joyner, D., Hazen, T. C., Arkin, A. P., Wall, J. D., Singh, A. K. & Keasling, J. D., 2011, In : PLOS ONE. 6, 6, p. e21470

    Research output: Contribution to journalJournal articleResearchpeer-review

  112. Published

    Using electronic patient records to discover disease correlations and stratify patient cohorts

    Roque, F. S., Jensen, P. B., Schmock, H., Dalgaard, M., Andreatta, M., Hansen, T., Søeby, K., Bredkjær, S., Juul, Anders, Werge, Thomas, Jensen, Lars Juhl & Brunak, Søren, 2011, In : P L o S Computational Biology. 7, 8, p. e1002141 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  113. Published

    Bioinformatics-driven identification and examination of candidate genes for non-alcoholic fatty liver disease

    Banasik, Karina, Justesen, Johanne Marie, Hornbak, M., Krarup, N. T., Gjesing, Anette Marianne Prior, Sandholt, C. H., Søndergaard Jensen, T., Grarup, Niels, Andersson, Å., Jørgensen, T., Witte, D. R., Sandbæk, A., Lauritzen, T., Thorens, B., Brunak, Søren, Sørensen, Thorkild I.A., Pedersen, Oluf Borbye & Hansen, Torben, 1 Jan 2011, In : P L o S One. 6, 1, p. e16542

    Research output: Contribution to journalJournal articleResearchpeer-review

  114. Published

    Effective representation and storage of mass spectrometry-based proteomic data sets for the scientific community

    Olsen, Jesper Velgaard & Mann, Matthias, 1 Jan 2011, In : Science Signaling. 4, 160, p. pe7

    Research output: Contribution to journalJournal articleResearchpeer-review

  115. Published

    GeLCMS for in-depth protein characterization and advanced analysis of proteomes

    Lundby, Alicia & Olsen, Jesper Velgaard, 1 Jan 2011, Gel-Free Proteomics Methods and Protocols. Vol. 753. p. 143-55 13 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  116. Published

    Phospho.ELM: a database of phosphorylation sites--update 2011

    Dinkel, H., Chica, C., Via, A., Gould, C. M., Jensen, Lars Juhl, Gibson, T. J. & Diella, F., 1 Jan 2011, In : Nucleic Acids Symposium Series. 39, Database issue, p. D261-7

    Research output: Contribution to journalJournal articleResearchpeer-review

  117. Published

    The SOCS2 Ubiquitin Ligase Complex Regulates Growth Hormone Receptor Levels

    Vesterlund, M., Zadjali, F., Persson, T., Nielsen, Michael Lund, Kessler, B. M., Norstedt, G. & Flores Morales, A., 1 Jan 2011, In : P L o S One. 6, 9, p. e25358 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  118. Published

    Evidence that OGG1 glycosylase protects neurons against oxidative DNA damage and cell death under ischemic conditions

    Liu, D., Croteau, D. L., Souza-Pinto, N., Pitta, M., Tian, J., Wu, C., Jiang, H., Mustafa, K., Keijzers, Guido, Bohr, Vilhelm & Mattson, M. P., Feb 2011, In : Journal of Cerebral Blood Flow and Metabolism. 31, 2, p. 680-692 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  119. Published

    Direct effects of FGF21 on glucose uptake in human skeletal muscle: implications for type 2 diabetes and obesity

    Mashili, F. L., Austin, R. L., Deshmukh, Atul Shahaji, Fritz, T., Caidahl, K., Bergdahl, K., Zierath, Juleen R, Chibalin, A. V., Moller, D. E., Kharitonenkov, A. & Krook, A., Mar 2011, In : Diabetes - Metabolism: Research and Reviews (Print Edition). 27, 3, p. 286-97 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  120. Published

    Targeted proteomics for metabolic pathway optimization: application to terpene production

    Redding-Johanson, A. M., Batth, Tanveer Singh, Chan, R., Krupa, R., Szmidt, H. L., Adams, P. D., Keasling, J. D., Lee, T. S., Mukhopadhyay, A. & Petzold, C. J., Mar 2011, In : Metabolic Engineering. 13, 2, p. 194-203 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  121. Published

    53BP1 nuclear bodies form around DNA lesions generated by mitotic transmission of chromosomes under replication stress

    Lukas, Claudia, Savic, V., Bekker-Jensen, Simon Holst, Doil, C., Neumann, B., Pedersen, R. S., Grøfte, M., Chan, K. L., Hickson, Ian David, Bartek, J. & Lukas, Jiri, 1 Mar 2011, In : Nature Cell Biology. 13, 3, p. 243-53 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  122. Published

    Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level

    Danielsen, J. M. R., Sylvestersen, K. B., Bekker-Jensen, Simon Holst, Szklarczyk, D., Poulsen, J. W., Horn, H., Jensen, Lars Juhl, Mailand, Niels & Nielsen, Michael Lund, 1 Mar 2011, In : Molecular and Cellular Proteomics. 10, 3, p. M110.003590

    Research output: Contribution to journalJournal articleResearchpeer-review

  123. Published

    Analysis of the Arabidopsis cytosolic proteome highlights subcellular partitioning of central plant metabolism

    Ito, J., Batth, Tanveer Singh, Petzold, C. J., Redding-Johanson, A. M., Mukhopadhyay, A., Verboom, R., Meyer, E. H., Millar, A. H. & Heazlewood, J. L., 1 Apr 2011, In : Journal of Proteome Research. 10, 4, p. 1571-82 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  124. Published

    Andromeda - a peptide search engine integrated into the MaxQuant environment

    Cox, J., Neuhauser, N., Michalski, A., Scheltema, R. A., Olsen, Jesper Velgaard & Mann, Matthias, 1 Apr 2011, In : Journal of Proteome Research. 10, 4, p. 1794-805 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  125. Published

    Meta-analysis of heterogeneous data sources for genome-scale identification of risk genes in complex phenotypes

    Pers, Tune H, Hansen, N. T., Hansen, K. L., Koefoed, P., Dworzynski, P., Miller, M. L., Flint, T. J., Mellerup, Erling Thyge, Dam, Henrik, Andreassen, O. A., Djurovic, S., Melle, I., Børglum, A. D., Werge, Thomas, Purcell, S., Ferreira, M. A., Kouskoumvekaki, I., Workman, C., Hansen, Torben, Mors, O. & Brunak, Søren, 11 Apr 2011, In : Genetic Epidemiology. 35, 5, p. 318-332 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  126. Published

    Cost-effective multiplexing before capture allows screening of 25 000 clinically relevant SNPs in childhood acute lymphoblastic leukemia

    Wesolowska, A., Gautier, L., Weinhold, N., Audouze, K. M. L., Brunak, Søren, Sicheritz-Ponten, T., Gupta, R., Dalgaard, M. D., Nielsen, B. F., Leffers, H., Borst, L., Helt, L. R., Nersting, J., Schmiegelow, Kjeld, Bak, Mads & Tommerup, Niels, 1 Jun 2011, In : Leukemia. 25, 6, p. 1001-1006 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  127. Published

    Pathogenesis and biomarkers of carcinogenesis in ulcerative colitis

    Thorsteinsdottir, S., Gudjónsson, Thorkell, Nielsen, Ole Haagen, Vainer, B. & Seidelin, Jakob Benedict, 7 Jun 2011, In : Nature Reviews. Gastroenterology & Hepatology. 8, 7, p. 395-404 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  128. Published

    Unique interaction pattern for a functionally biased ghrelin receptor agonist

    Sivertsen, B. B., Lang, M., Frimurer, T. M., Holliday, N. D., Bach, Anders, Els, S., Engelstoft, M. S., Petersen, P. S., Madsen, A. N., Schwartz, Thue W., Beck-Sickinger, A. G. & Holst, Birgitte, 10 Jun 2011, In : The Journal of Biological Chemistry. 286, 23, p. 20845-20860 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  129. Published

    The ubiquitin- and SUMO-dependent signaling response to DNA double-strand breaks

    Bekker-Jensen, Simon Holst & Mailand, Niels, 12 Jun 2011, In : FEBS letters. 585, p. 2914-2919 6 p.

    Research output: Contribution to journalReviewResearchpeer-review

  130. Published

    Separation of the gluconeogenic and mitochondrial functions of pgc-1α through s6 kinase

    Lustig, Y., Ruas, J. L., Estall, J. L., Lo, J. C., Devarakonda, S., Laznik, D., Choi, J. H., Spiegelman, B. M., Ono, H. & Olsen, Jesper Velgaard, 15 Jun 2011, In : Genes & Development. 25, 12, p. 1232-1244 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  131. Published

    Pinpointing Phosphorylation Sites: Quantitative Filtering and a Novel Site-specific x-Ion Fragment

    Kelstrup, C. D., Hekmat, O., Francavilla, C. & Olsen, Jesper Velgaard, 1 Jul 2011, In : Journal of Proteome Research. 10, 7, p. 2937-48 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  132. Published

    The association between anxiety and measures of glycaemia in a population-based diabetes screening programme

    Aujla, N., Davies, Michael Jonathan, Skinner, Timothy, Gray, L. J., Webb, D. R., Srinivasan, Balaji & Khunti, K., 1 Jul 2011, In : Diabetic Medicine. 28, 7, p. 785-788 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  133. Published

    Quantitative, high-resolution proteomics for data-driven systems biology

    Cox, J. & Mann, Matthias, 7 Jul 2011, In : Annual Review of Biochemistry. 80, p. 273-299 27 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  134. Published

    Phosphorylation of the autophagy receptor optineurin restricts Salmonella growth

    Wild, P., Farhan, H., McEwan, D. G., Wagner, S., Rogov, V. V., Brady, N. R., Richter, B., Korac, J., Waidmann, O., Choudhary, Chuna Ram, Dötsch, V., Bumann, D. & Dikic, I., 8 Jul 2011, In : Science. 333, 6039, p. 228-33 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  135. Published

    Binding Mode of a Novel MPEP-Derived Metabotropic Glutamate Receptor Subtype 5 (mGluR5) NAM, 1,3-Bis(pyridin-2-ylethynyl)Benzene

    Molck, C., Harpsøe, Kasper, Gloriam, David E., Kaae, B. H., Jimenez, H. N., Uberti, M. A., Topiol, S., Clausen, Rasmus Prætorius, Madsen, Ulf, Nielsen, S. M., Mathiesen, Jesper M. & Bräuner-Osborne, Hans, Sep 2011, In : Current Neuropharmacology. 9, p. 43-43

    Research output: Contribution to journalConference abstract in journalResearch

  136. Published

    Optimization of a heterologous mevalonate pathway through the use of variant HMG-CoA reductases

    Ma, S. M., Garcia, D. E., Redding-Johanson, A. M., Friedland, G. D., Chan, R., Batth, Tanveer Singh, Haliburton, J. R., Chivian, D., Keasling, J. D., Petzold, C. J., Lee, T. S. & Chhabra, S. R., Sep 2011, In : Metabolic Engineering. 13, 5, p. 588-97 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  137. Published

    Ten simple rules for getting help from online scientific communities

    Dall'olio, G. M., Marino, J., Schubert, M., Keys, K. L., Stefan, M. I., Gillespie, C. S., Poulain, P., Shameer, K., Sugar, R., Invergo, B. M., Jensen, Lars Juhl, Bertranpetit, J. & Laayouni, H., 1 Sep 2011, In : P L o S Computational Biology. 7, 9, p. e1002202

    Research output: Contribution to journalJournal articleResearchpeer-review

  138. Published

    A Proteome-wide, Quantitative Survey of In Vivo Ubiquitylation Sites Reveals Widespread Regulatory Roles

    Wagner, S. A., Beli, P., Weinert, B. T., Nielsen, Michael Lund, Cox, J., Mann, Matthias & Choudhary, Chuna Ram, 1 Oct 2011, In : Molecular and Cellular Proteomics. 10, 10, p. M111.013284

    Research output: Contribution to journalJournal articleResearchpeer-review

  139. Published

    Liver X receptor agonist downregulates growth hormone signaling in the liver

    Zadjali, F., Santana-Farre, R., Mirecki-Garrido, M., Ellis, E., Norstedt, G., Fernandez-Perez, L. & Flores-Morales, A., 1 Nov 2011, In : Hormone Molecular Biology and Clinical Investigation. 8, 2, p. 471-8 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  140. Published

    Structure of a Blinkin-BUBR1 complex reveals an interaction crucial for kinetochore-mitotic checkpoint regulation via an unanticipated binding Site

    Bolanos-Garcia, V. M., Lischetti, T., Matak-Vinković, D., Cota, E., Simpson, P. J., Chirgadze, D. Y., Spring, D. R., Robinson, C. V., Nilsson, Jakob & Blundell, T. L., 9 Nov 2011, In : Structure. 19, 11, p. 1691-700 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  141. Published

    A systematic study of site-specific GalNAc-type O-glycosylation modulating proprotein convertase processing

    Schjoldager, Katrine Ter-Borch Gram, Vester-Christensen, M. B., Goth, Christoffer Knak, Petersen, T. N., Brunak, Søren, Bennett, Eric Paul, Levery, S. B. & Clausen, Henrik, 18 Nov 2011, In : Journal of Biological Chemistry. 286, 46, p. 40122-32 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  142. Published

    The AAA-ATPase VCP/p97 promotes 53BP1 recruitment by removing L3MBTL1 from DNA double-strand breaks

    Acs, K., Luijsterburg, M. S., Ackermann, Leena, Salomons, F. A., Hoppe, T. & Dantuma, N. P., 27 Nov 2011, In : Nature Structural & Molecular Biology. 18, 12, p. 1345-50 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  143. 2012
  144. Published

    A genome-wide association study of men with symptoms of testicular dysgenesis syndrome and its network biology interpretation

    Dalgaard, M. D., Weinhold, N., Edsgärd, D., Silver, J. D., Pers, T. H., Nielsen, J. E., Jørgensen, N., Juul, Anders, Gerds, Thomas Alexander, Giwercman, A., Giwercman, Y. L., Cohn-Cedermark, G., Virtanen, H. E., Toppari, J., Daugaard, G., Jensen, T. S., Brunak, Søren, Rajpert-De Meyts, E., Skakkebæk, N. E., Leffers, H. & Gupta, R., 2012, In : Journal of Medical Genetics. 49, 1, p. 58-65 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  145. Published

    A new non-catalytic role for ubiquitin ligase RNF8 in unfolding higher-order chromatin structure

    Luijsterburg, M. S., Acs, K., Ackermann, L., Wiegant, W. W., Bekker-Jensen, Simon Holst, Larsen, D. H., Khanna, K. K., van Attikum, H., Mailand, Niels & Dantuma, N. P., 2012, In : E M B O Journal. 31, 11, p. 2511-27 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  146. Published

    A thermophilic ionic liquid-tolerant cellulase cocktail for the production of cellulosic biofuels

    Park, J. I., Steen, E. J., Burd, H., Evans, S. S., Redding-Johnson, A. M., Batth, Tanveer Singh, Benke, P. I., D'haeseleer, P., Sun, N., Sale, K. L., Keasling, J. D., Lee, T. S., Petzold, C. J., Mukhopadhyay, A., Singer, S. W., Simmons, B. A. & Gladden, J. M., 2012, In : PLoS ONE. 7, 5, p. e37010

    Research output: Contribution to journalJournal articleResearchpeer-review

  147. Published

    Addicted to PAR? A closer look at PARP inhibitor sensitivity

    Altmeyer, M., 2012, In : Cell Cycle. 11, 21, p. 3916 1 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  148. Published

    Cometin is a novel neurotrophic factor that promotes neurite outgrowth and neuroblast migration in vitro and supports survival of spiral ganglion neurons in vivo

    Jørgensen, J. R., Fransson, A., Fjord-Larsen, L., Thompson, L. H., Houchins, J. P., Andrade, N., Torp, M., Kalkkinen, N., Andersson, E., Lindvall, O., Ulfendahl, M., Brunak, Søren, Johansen, T. E. & Wahlberg, L. U., 2012, In : Experimental Neurology. 233, 1, p. 172-81 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  149. Published

    Comprehensive profiling of proteome changes upon sequential deletion of deubiquitylating enzymes

    Poulsen, J. W., Madsen, C. T., Young, C., Kelstrup, C. D., Grell, H. C., Henriksen, P., Jensen, Lars Juhl & Nielsen, Michael Lund, 2012, In : Journal of Proteomics. 75, 13, p. 3886-97 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  150. Published

    Correction to Feasibility of Large-Scale Phosphoproteomics with Higher Energy Collisional Dissociation Fragmentation

    Nagaraj, N., D'Souza, R. C. J., Cox, J., Olsen, Jesper Velgaard & Mann, Matthias, 2012, In : Journal of Proteome Research.

    Research output: Contribution to journalJournal articleResearchpeer-review

  151. Published

    DNA damage-inducible SUMOylation of HERC2 promotes RNF8 binding via a novel SUMO-binding Zinc finger

    Danielsen, J. M. R., Povlsen, L. K., Villumsen, B. H., Streicher, W., Nilsson, Jakob, Wikström, M., Bekker-Jensen, Simon Holst & Mailand, Niels, 2012, In : Journal of Cell Biology. 197, 2, p. 179-87 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  152. Published

    DVC1 (C1orf124) is a DNA damage-targeting p97 adaptor that promotes ubiquitin-dependent responses to replication blocks

    Mosbech, A., Gibbs-Seymour, I., Kagias, K., Thorslund, T., Beli, P., Povlsen, L., Nielsen, Sofie Vincents, Smedegaard, S., Sedgwick, G., Lukas, Claudia, Hartmann-Petersen, Rasmus, Lukas, Jiri, Choudhary, Chuna Ram, Pocock, R. D. J., Bekker-Jensen, Simon Holst & Mailand, Niels, 2012, In : Nature Structural and Molecular Biology. 19, 11, p. 1084-92 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  153. Published

    DistiLD Database: diseases and traits in linkage disequilibrium blocks

    Palleja, A., Horn, H., Eliasson, S. & Jensen, Lars Juhl, 2012, In : Nucleic Acids Research. 40, Database issue, p. D1036-40

    Research output: Contribution to journalJournal articleResearchpeer-review

  154. Published

    Genes adopt non-optimal codon usage to generate cell cycle-dependent oscillations in protein levels

    Frenkel-Morgenstern, M., Danon, T., Christian, T., Igarashi, T., Cohen, L., Hou, Y. & Jensen, Lars Juhl, 2012, In : Molecular Systems Biology. 8, p. 572

    Research output: Contribution to journalJournal articleResearchpeer-review

  155. Published

    Genetic and environmental risk factors in congenital heart disease functionally converge in protein networks driving heart development

    Hansen, K. L., Greenway, S. C., Rosenfeld, J. A., Wakimoto, H., Gorham, J. M., Segrè, A. V., Roberts, A. E., Smoot, L. B., Pu, W. T., C Pereira, A., Mesquita, S. M., Tommerup, Niels, Brunak, Søren, Ballif, B. C., Shaffer, L. G., Donahoe, P. K., Daly, M. J., Seidman, J. G., Seidman, C. E. & Larsen, Lars Allan, 2012, In : Proceedings of the National Academy of Sciences USA (PNAS). 109, 35, p. 14035-40 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  156. Published

    Histone deacetylases 1 and 3 but not 2 mediate cytokine-induced beta cell apoptosis in INS-1 cells and dispersed primary islets from rats and are differentially regulated in the islets of type 1 diabetic children

    Lundh, M., Christensen, D. P., Damgaard Nielsen, M., Richardson, S. J., Dahllöf, M. S., Skovgaard, T., Berthelsen, J., Dinarello, C. A., Stevenazzi, A., Mascagni, P., Grunnet, L. G., Morgan, N. G. & Mandrup-Poulsen, Thomas, 2012, In : Diabetologia. 55, 9, p. 2421-31

    Research output: Contribution to journalJournal articleResearchpeer-review

  157. Published

    Human RNF169 is a negative regulator of the ubiquitin-dependent response to DNA double-strand breaks

    Poulsen, M., Lukas, C., Lukas, J., Bekker-Jensen, Simon Holst & Mailand, Niels, 2012, In : Journal of Cell Biology. 197, 2, p. 189-99 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  158. Published

    ICLs: a chicken without an egg

    Bekker-Jensen, Simon Holst & Mailand, Niels, 2012, In : Nature Reviews. Molecular Cell Biology. 13, 6, p. 342

    Research output: Contribution to journalReviewResearchpeer-review

  159. Published

    Identification of novel type 1 diabetes candidate genes by integrating genome-wide association data, protein-protein interactions, and human pancreatic islet gene expression

    Bergholdt, R., Brorsson, C., Palleja, A., Berchtold, L. A., Fløyel, T., Bang-Berthelsen, C. H., Frederiksen, K. S., Jensen, Lars Juhl, Størling, J. & Pociot, F., 2012, In : Diabetes. 61, 4, p. 954-62 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  160. Published

    Influence of neonatal hypothyroidism on hepatic gene expression and lipid metabolism in adulthood

    Santana-Farré, R., Mirecki-Garrido, M., Bocos, C., Henríquez-Hernández, L. A., Kahlon, N., Herrera, E., Norstedt, G., Parini, P., Flores Morales, A. & Fernández-Pérez, L., 2012, In : PLOS ONE. 7, 5, p. e37386 e37386.

    Research output: Contribution to journalJournal articleResearchpeer-review

  161. Published

    Mining electronic health records: towards better research applications and clinical care

    Jensen, P. B., Jensen, Lars Juhl & Brunak, Søren, 2012, In : Nature Reviews. Genetics. 13, 6, p. 395-405 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  162. Published

    Multiple independent analyses reveal only transcription factors as an enriched functional class associated with microRNAs

    Croft, L. J., Szklarczyk, D., Jensen, Lars Juhl & Gorodkin, Jan, 2012, In : B M C Systems Biology. 6, 1, p. 90

    Research output: Contribution to journalJournal articleResearchpeer-review

  163. Published

    Optimized Fast and Sensitive Acquisition Methods for Shotgun Proteomics on a Quadrupole Orbitrap Mass Spectrometer

    Kelstrup, C. D., Young, C., Lavallee, R., Nielsen, Michael Lund & Olsen, Jesper Velgaard, 2012, In : Journal of Proteome Research. p. 3487-3497 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  164. Published

    Pdx1 is post-translationally modified in vivo and serine 61 is the principal site of phosphorylation

    Frogne, T., Sylvestersen, K. B., Kubicek, S., Nielsen, Michael Lund & Hecksher-Sørensen, J., 2012, In : P L o S One. 7, 4, p. e35233

    Research output: Contribution to journalJournal articleResearchpeer-review

  165. Published

    Pharmacological characterization and modeling of the binding sites of novel 1,3-bis(pyridinylethynyl)benzenes as metabotropic glutamate receptor 5-selective negative allosteric modulators

    Mølck, C., Harpsøe, Kasper, Gloriam, David E., Clausen, Rasmus Prætorius, Madsen, Ulf, Pedersen, L., Jimenez, H. N., Nielsen, S. M., Mathiesen, Jesper M. & Bräuner-Osborne, Hans, 2012, In : Molecular Pharmacology. 82, 5, p. 929-37 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  166. Published

    Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae

    Henriksen, P., Wagner, S. A., Weinert, B. T., Sharma, S., Bacinskaja, G., Rehman, M., Juffer, A. H., Walther, T. C., Lisby, Michael & Choudhary, Chuna Ram, 2012, In : Molecular & Cellular Proteomics. 11, 11, p. 1510-1522 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  167. Published

    Proteomic analyses reveal divergent ubiquitylation site patterns in murinetissues

    Wagner, S. A., Beli, P., Weinert, B. T., Schölz, C. F., Kelstrup, C. D., Young, C., Nielsen, Michael Lund, Olsen, Jesper Velgaard, Brakebusch, Cord Herbert & Choudhary, Chuna Ram, 2012, In : Molecular & Cellular Proteomics.

    Research output: Contribution to journalJournal articleResearchpeer-review

  168. Published

    Proteomic analysis of a pleistocene mammoth femur reveals more than one hundred ancient bone proteins

    Cappellini, Enrico, Jensen, Lars Juhl, Szklarczyk, D. M., Ginolhac, A., Rodrigues da Fonseca, Rute Andreia, Stafford jr., T., Holen, S. R., Collins, M. J., Orlando, L. A. A., Willerslev, Eske, Gilbert, M Thomas P & Olsen, Jesper Velgaard, 2012, In : Journal of Proteome Research. 11, 2, p. 917-926 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  169. Published

    Proteomic investigations reveal a role for RNA processing factor THRAP3 in the DNA damage response

    Beli, P., Lukashchuk, N., Wagner, S. A., Weinert, B. T., Olsen, Jesper Velgaard, Baskcomb, L., Mann, Matthias, Jackson, S. P. & Choudhary, Chuna Ram, 2012, In : Molecular Cell. 46, 2, p. 212-25 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  170. Published

    RNF8 and RNF168 but not HERC2 are required for DNA damage-induced ubiquitylation in chicken DT40 cells

    Østergaard, Vibe Hallundbæk, Pentzold, C., Pedersen, R. T., Iosif, S., Alpi, A., Bekker-Jensen, Simon Holst, Mailand, Niels & Lisby, Michael, 2012, In : D N A Repair. 11, 11, p. 892–905 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  171. Published

    SOCS2 deletion protects against hepatic steatosis but worsens insulin resistance in high-fat-diet-fed mice

    Zadjali, F., Santana-Farre, R., Vesterlund, M., Carow, B., Mirecki-Garrido, M., Hernandez-Hernandez, I., Flodström-Tullberg, M., Parini, P., Rottenberg, M., Norstedt, G., Fernandez-Perez, L. & Flores Morales, A., 2012, In : FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 26, 8, p. 3282-91 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  172. Published

    STITCH 3: zooming in on protein-chemical interactions

    Kuhn, M., Szklarczyk, D., Franceschini, A., von Mering, C., Jensen, Lars Juhl & Bork, P., 2012, In : Nucleic Acids Research. 40, Database issue, p. D876-80

    Research output: Contribution to journalJournal articleResearchpeer-review

  173. Published

    Suppressor of Cytokine Signaling 6 (SOCS6) Negatively Regulates Flt3 Signal Transduction through Direct Binding to Phosphorylated Tyrosines 591 and 919 of Flt3

    Kazi, J. U., Sun, J., Phung, B., Zadjali, F., Flores Morales, A. & Rönnstrand, L., 2012, In : The Journal of Biological Chemistry. 287, 43, p. 36509-17 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  174. Published

    The DNA damage- and transcription-associated protein Paxip1 controls thymocyte development and emigration

    Callen, E., Faryabi, R. B., Daniel, J. A., Nussenzweig, A., Luckey, M., Park, J., Hao, B., Krangel, M. S., Yang, W., Peng, W., Sun, H., Dressler, G., Chi, H. & Ge, K., 2012, In : Immunity. 37, 6, p. 971-985 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  175. Published

    The Ndc80 internal loop is required for recruitment of the Ska complex to establish end-on microtubule attachment to kinetochores

    Zhang, G., Kelstrup, C. D., Hu, X., Hansen, M. J. K., Singleton, M. R., Olsen, Jesper Velgaard & Nilsson, Jakob, 2012, In : Journal of Cell Science. p. 3243-3253 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  176. Published

    The Ubiquitin Ligase XIAP Recruits LUBAC for NOD2 Signaling in Inflammation and Innate Immunity

    Damgaard, R. B., Nachbur, U., Yabal, M., Wong, W. W., Fiil, B. K., Kastirr, M., Rieser, E., Rickard, J. A., Bankovacki, A., Peschel, C., Ruland, J., Bekker-Jensen, Simon Holst, Mailand, Niels, Kaufmann, T., Strasser, A., Walczak, H., Silke, J., Jost, P. J. & Gyrd-Hansen, M., 2012, In : Molecular Cell. 46, 6, p. 746-58 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  177. Published

    Transcriptional regulation is a major controller of cell cycle transition dynamics

    Romanel, A., Jensen, Lars Juhl, Cardelli, L. & Csikász-Nagy, A., 2012, In : P L o S One. 7, 1, p. e29716

    Research output: Contribution to journalJournal articleResearchpeer-review

  178. Published

    eggNOG v3.0: Orthologous groups covering 1133 organisms at 41 different taxonomic ranges

    Powell, S., Trachana, K., Letunic, I., Doerks, T., Bork, P., Szklarczyk, D., Jensen, Lars Juhl, Roth, A., Von Mering, C., Kuhn, M., Muller, J., Arnold, R. & Rattei, T., 2012, In : Nucleic Acids Research. 40, D1, p. D284-9

    Research output: Contribution to journalJournal articleResearchpeer-review

  179. Published

    Modular engineering of L-tyrosine production in Escherichia coli

    Juminaga, D., Baidoo, E. E. K., Redding-Johanson, A. M., Batth, Tanveer Singh, Burd, H., Mukhopadhyay, A., Petzold, C. J. & Keasling, J. D., Jan 2012, In : Applied and Environmental Microbiology. 78, 1, p. 89-98 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  180. Published

    Self-hydroxylation of the splicing factor lysyl hydroxylase, JMJD6

    Mantri, M., Webby, C. J., Loik, N. D., Hamed, R. B., McDonough, M. A., McCullagh, J. S. O., Schofield, C. J., Wolf, A., Nielsen, Michael Lund & Böttger, A., 1 Jan 2012, In : MedChemComm. 3, 1, p. 80-85 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  181. Published

    The architecture of the BubR1 tetratricopeptide tandem repeat defines a protein motif underlying mitotic checkpoint-kinetochore communication

    Bolanos-Garcia, V. M., Nilsson, Jakob & Blundell, T. L., 1 Jan 2012, In : Bioarchitecture. 2, 1, p. 23-27 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  182. Published

    The molecular basis of ATM-dependent dimerization of the Mdc1 DNA damage checkpoint mediator.

    Jungmichel, S., Clapperton, J. A., Janette, L., Hari, F. J., Spycher, C., Pavic, L., Li, J., Haire, L. F., Bonalli, M., Larsen, D. H., Lukas, C., Lukas, J., MacMillan, D., Nielsen, Michael Lund, Stucki, M. & Smerdon, S. J., 10 Jan 2012, In : Nucleic Acids Research. 40, 9, p. 4913-4928 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  183. Published

    Molecular scissors for in situ cellular repair

    Prieto, J., Molina, Rafael & Montoya, Guillermo, 31 Jan 2012, In : Critical Reviews in Biochemistry and Molecular Biology. 47, 3, p. 207-21 15 p.

    Research output: Contribution to journalReviewResearchpeer-review

  184. Published

    Androgen receptor signalling in peritubular myoid cells is essential for normal differentiation and function of adult Leydig cells

    Welsh, M., Moffat, L., Belling, Kirstine G, de França, L. R., Segatelli, T. M., Saunders, P. T. K., Sharpe, R. M. & Smith, L. B., Feb 2012, In : International Journal of Andrology. Supplement. 35, 1, p. 25-40 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  185. Published

    Androgen-independent effects of Serenoa repens extract (Prostasan®) on prostatic epithelial cell proliferation and inflammation

    Iglesias Gato, Diego, Carsten, T., Vesterlund, M., Pousette, A., Schoop, R. & Norstedt, G., Feb 2012, In : Phytotherapy Research. 26, 2, p. 259-64 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  186. Published

    Proteomics for biomedicine: A half-completed journey

    Mann, Matthias, 1 Feb 2012, In : EMBO Molecular Medicine. 4, 2, p. 75-77 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  187. Published

    Advancing cell biology through proteomics in space and time (PROSPECTS)

    Lamond, A. I., Uhlen, M., Horning, S., Makarov, A., Robinson, C. V., Serrano, L., Hartl, F. U., Baumeister, W., Werenskiold, A. K., Mann, Matthias, Andersen, J. S., Vorm, O., Linial, M. & Aebersold, R., 1 Mar 2012, In : Molecular & Cellular Proteomics. 11, 3, 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  188. Published

    Effects of 2 weeks lower limb immobilization and two separate rehabilitation regimens on gastrocnemius muscle protein turnover signaling and normalization genes

    Nedergaard, A., Jespersen, J. G., Pingel, Jessica, Christensen, B., Sroczynski, N., Langberg, Henning, Kjær, Michael & Schjerling, P., 28 Mar 2012, In : BMC Research Notes. 5, 1, p. 166 1 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  189. Published

    A role for small RNAs in DNA double-strand break repair

    Wei, W., Ba, Z., Wu, Y., Ma, Y., Qi, Y., Gao, M., Danielsen, J. M. R., Yang, Y., Amiard, S. & White, C. I., 30 Mar 2012, In : Cell. 149, 1, p. 101-112 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  190. Published

    Sequencing chromosomal abnormalities reveals neurodevelopmental loci that confer risk across diagnostic boundaries

    Talkowski, M. E., Rosenfeld, J. A., Blumenthal, I., Pillalamarri, V., Chiang, C., Heilbut, A., Ernst, C., Hanscom, C., Rossin, E., Lindgren, A. M., Pereira, S., Ruderfer, D., Kirby, A., Ripke, S., Harris, D. J., Lee, J., Ha, K., Kim, H., Solomon, B. D., Gropman, A. L., Lucente, D., Sims, K., Ohsumi, T. K., Borowsky, M. L., Loranger, S., Quade, B., Hansen, K. L., Miles, J., Wu, B., Shen, Y., Neale, B., Shaffer, L. G., Daly, M. J., Morton, C. C. & Gusella, J. F., 27 Apr 2012, In : Cell. 149, 3, p. 525-37 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  191. Published

    Bioinformatics Training Network (BTN): a community resource for bioinformatics trainers

    Schneider, M. V., Walter, P., Blatter, M., Watson, J., Brazas, M. D., Rother, K., Budd, A., Via, A., van Gelder, C. W. G., Jacob, J., Fernandes, P., Nyrönen, T. H., De Las Rivas, J., Blicher, T., Jimenez, R. C., Loveland, J., McDowall, J., Jones, P., Vaughan, B. W., Lopez, R., Attwood, T. K. & Brooksbank, C., May 2012, In : Briefings in Bioinformatics. 13, 3, p. 383-9 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  192. Published

    Knowledge engineering for health: a new discipline required to bridge the "ICT gap" between research and healthcare

    Beck, T., Gollapudi, S., Brunak, Søren, Graf, N., Lemke, H. U., Dash, D., Buchan, I., Díaz, C., Sanz, F. & Brookes, A. J., May 2012, In : Human Mutation. 33, 5, p. 797-802 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  193. Published

    Reversed binding of a small molecule ligand in homologous chemokine receptors - differential role of extracellular loop 2

    Jensen, Per Claudi, Thiele, S., Steen, A., Elder, A., Kolbeck, R., Ghosh, S., Frimurer, Thomas Michael & Rosenkilde, Mette, May 2012, In : British Journal of Pharmacology. 166, 1, p. 258-75 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  194. Published

    Using text-mining techniques in electronic patient records to identify ADRs from medicine use

    Warrer, P., Hansen, E. H., Jensen, Lars Juhl & Aagaard, L., May 2012, In : British Journal of Clinical Pharmacology. 73, 5, p. 674-684 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  195. Published

    Multimodel pathway enrichment methods for functional evaluation of expression regulation

    Kirik, U., Cifani, P., Albrekt, A., Lindstedt, M., Heyden, A. & Levander, F., 4 May 2012, In : Journal of Proteome Research. 11, 5, p. 2955-67 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  196. Published

    Protein expression changes in ovarian cancer during the transition from benign to malignant

    Waldemarson, S., Krogh, M., Alaiya, A., Kirik, U., Schedvins, K., Auer, G., Hansson, K. M., Ossola, R., Aebersold, R., Lee, H., Malmström, J. & James, P., 4 May 2012, In : Journal of Proteome Research. 11, 5, p. 2876-89 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  197. Published

    Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues

    Lundby, Alicia, Secher, A., Lage, K., Nordsborg, Nikolai Baastrup, Dmytriyev, A., Lundby, C. & Olsen, Jesper Velgaard, 6 Jun 2012, In : Nature Communications. 3, p. 1-10 10 p., Article 876.

    Research output: Contribution to journalJournal articleResearchpeer-review

  198. Published

    Covalent attachment of antagonists to the a7 nicotinic acetylcholine receptor: synthesis and reactivity of substituted maleimides

    Ambrus, J. I., Halliday, J. I., Kanizaj, N., Absalom, N., Harpsøe, Kasper, Balle, T., Chebib, M. & McLeod, M. D., 7 Jul 2012, In : Chemical Communications. 48, 53, p. 6699-6701 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  199. Published

    Thermoascus aurantiacus is a promising source of enzymes for biomass deconstruction under thermophilic conditions

    McClendon, S. D., Batth, Tanveer Singh, Petzold, C. J., Adams, P. D., Simmons, B. A. & Singer, S. W., 28 Jul 2012, In : Biotechnology for Biofuels. 5, 1, p. 54

    Research output: Contribution to journalJournal articleResearchpeer-review

  200. Published

    Inactivation of barley limit dextrinase inhibitor by thioredoxin-catalysed disulfide reduction

    Jensen, J. M., Hägglund, Per Mårten, Christensen, H. E. M. & Svensson, B., 30 Jul 2012, In : FEBS letters. 586, 16, p. 2479-2482 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  201. Published

    LEDGF (p75) promotes DNA-end resection and homologous recombination

    Daugaard, M., Baude, A., Fugger, K., Povlsen, L. K., Beck, H., Sørensen, Claus Storgaard, Petersen, N. H. T., Sorensen, P. H. B., Lukas, Claudia, Bartek, J., Lukas, Jiri, Rohde, M. & Jaattela, Marja, Aug 2012, In : Nature Structural & Molecular Biology. 19, 8, p. 803-810 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  202. Published

    Non-specific protein-DNA interactions control I-CreI target binding and cleavage

    Molina, Rafael, Redondo, P., Stella, Stefano, Marenchino, M., D'Abramo, M., Gervasio, F. L., Charles Epinat, J., Valton, J., Grizot, S., Duchateau, P., Prieto, J. & Montoya, Guillermo, 1 Aug 2012, In : Nucleic Acids Research. 40, 14, p. 6936-6945 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  203. Published

    Loss of ATM kinase activity leads to embryonic lethality in mice

    Daniel, J. A., Pellegrini, M., Filsuf, D., Nussenzweig, A., Belkina, N. V., Feigenbaum, L., Lee, B., Sleckman, B. P., You, Z., Guo, Z. & Paull, T. T., 6 Aug 2012, In : Journal of Cell Biology. 198, 3, p. 295-304 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  204. Published

    α4βδ GABA receptors are high-affinity targets for γ-hydroxybutyric acid (GHB)

    Absalom, N., Karim, N., Eghorn, L. F., Villumsen, I. S., Bay, T., Bräuner-Osborne, Hans, Frølund, Bente, Clausen, Rasmus Prætorius, Olsen, Jesper Velgaard, Knudsen, Gitte Moos, Chebib, M. & Wellendorph, Petrine, 14 Aug 2012, In : Proceedings of the National Academy of Sciences USA (PNAS). 109, 33, p. 13404-13409 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  205. Published

    The Rab-GTPase-activating protein TBC1D1 regulates skeletal muscle glucose metabolism

    Szekeres, F., Chadt, A., Tom, R. Z., Deshmukh, Atul Shahaji, Chibalin, A. V., Björnholm, M., Al-Hasani, H. & Zierath, Juleen R, 15 Aug 2012, In : American Journal of Physiology: Endocrinology and Metabolism. 303, 4, p. E524-33

    Research output: Contribution to journalJournal articleResearchpeer-review

  206. Published

    TRIP12 and UBR5 Suppress Spreading of Chromatin Ubiquitylation at Damaged Chromosomes

    Gudjónsson, Thorkell, Altmeyer, M. F., Savic, V., Toledo Lazaro, Luis Ignacio, Dinant, C., Grøfte, M., Bartkova, J., Poulsen, M., Oka, Y., Bekker-Jensen, Simon Holst, Mailand, Niels, Neumann, B., Heriche, J., Shearer, R., Saunders, D., Bartek, J., Lukas, Jiri & Lukas, Claudia, 17 Aug 2012, In : Cell. 150, 4, p. 697-709 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  207. Published

    SOCS1 cooperates with FLT3-ITD in the development of myeloproliferative disease by promoting the escape from external cytokine control

    Reddy, P. N. G., Serve, H., Brandts, C. H., Sargin, B., Choudhary, Chuna Ram, Müller-Tidow, C., Berdel, W. E., Stein, S. & Grez, M., 23 Aug 2012, In : Blood. 120, 8, p. 1691-1702 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  208. Published

    Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns

    Lundby, Alicia, Hansen, K. L., Weinert, B. T., Breinholt Bekker-Jensen, D., Secher, A., Skovgaard, T., Kelstrup, C., Dmytriyev, A., Choudhary, Chuna Ram, Lundby, C. & Olsen, Jesper Velgaard, 30 Aug 2012, In : Cell Reports. 2, 2, p. 419-431 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  209. Published

    5'-Cytosine-phosphoguanine (CpG) methylation impacts the activity of natural and engineered meganucleases

    Valton, J., Daboussi, F., Leduc, S., Molina, Rafael, Redondo, P., Macmaster, R., Montoya, Guillermo & Duchateau, P., 31 Aug 2012, In : The Journal of Biological Chemistry. 287, 36, p. 30139-50 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  210. Published

    Modulation of constitutive activity and signaling bias of the ghrelin receptor by conformational constraint in the second extracellular loop

    Mokrosinski, J., Frimurer, Thomas Michael, Sivertsen, B., Schwartz, Thue W. & Holst, Birgitte, Sep 2012, In : Journal of Biological Chemistry. 287, p. 33488-33502 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  211. Published

    Ubiquitin and the DNA damage response: a new handle on histones

    Bekker-Jensen, Simon Holst & Mailand, Niels, 1 Sep 2012, In : Cell Cycle. 11, 17, p. 3153 1 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  212. Published

    Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass

    Povlsen, L. K., Beli, P., Wagner, S. A., Poulsen, S. L., Sylvestersen, K. B., Poulsen, J. W., Nielsen, Michael Lund, Bekker-Jensen, Simon Holst, Mailand, Niels & Choudhary, Chuna Ram, Oct 2012, In : Nature Cell Biology. 14, 10, p. 1089-98 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  213. Published

    Loss of CBL E3-ligase activity in B-lineage childhood acute lymphoblastic leukaemia

    Martinelli, S., Checquolo, S., Consoli, F., Stellacci, E., Rossi, C., Silvano, M., Franciosa, Giulia, Flex, E., Cossu, C., De Luca, A., Foà, R., Cazzaniga, G., Biondi, A., Screpanti, I. & Tartaglia, M., 1 Oct 2012, In : British Journal of Haematology. 159, 1, p. 115-119 5 p.

    Research output: Contribution to journalLetterResearchpeer-review

  214. Published

    Melanin concentrating hormone receptor 1 (MCHR1) antagonists - Still a viable approach for obesity treatment?

    Högberg, T., Frimurer, Thomas Michael & Sasmal, P. K., 1 Oct 2012, In : Bioorganic & Medicinal Chemistry Letters. 22, 19, p. 6039-6047 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  215. Published

    Molecular characterization of oxysterol binding to the Epstein-Barr virus-induced gene 2 (GPR183)

    Benned-Jensen, T., Norn, Christoffer, Laurent, S., Madsen, C. M., Larsen, H. M., Arfelt, K. N., Wolf, R. M., Frimurer, Thomas Michael, Sailer, A. W. & Rosenkilde, Mette, 12 Oct 2012, In : The Journal of Biological Chemistry. 287, 42, p. 35470-83 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  216. Published

    Evaluation of candidate biomarkers to predict cancer cell sensitivity or resistance to PARP-1 inhibitor treatment

    Oplustilova, L., Wolanin, K., Bartkova, J., Lukas, Jiri, Bartek, J., Lau, A., O'Connor, M. J., Mistrik, M., Korinkova, G., Simkova, D., Bouchal, J. & Lenobel, R., 15 Oct 2012, In : Cell Cycle. 11, 20, p. 3837-3850 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  217. Published

    Histone displacement during nucleotide excision repair

    Dinant, C., Bartek, J. & Bekker-Jensen, Simon Holst, 17 Oct 2012, In : International Journal of Molecular Sciences (Online). 13, 10, p. 13322-13337 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  218. Published

    Expression, purification, crystallization and preliminary X-ray diffraction analysis of the dihydroorotase domain of human CAD

    Lallous, N., Grande-García, A., Molina, Rafael & Ramón-Maiques, S., 1 Nov 2012, In : Acta Crystallographica Section F: Structural Biology Communications. 68, Pt 11, p. 1341-5 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  219. Published

    A Novel Role of Human Holliday Junction Resolvase GEN1 in the Maintenance of Centrosome Integrity

    Gao, M., Danielsen, J. M. R., Wei, L., Zhou, D., Xu, Q., Li, M., Yang, Y., Wang, Z. & Tong, W., 16 Nov 2012, In : P L o S One. 7, 11, 13 p., e49687.

    Research output: Contribution to journalJournal articleResearchpeer-review

  220. Published

    Congenital diaphragmatic hernia interval on chromosome 8p23.1 characterized by genetics and protein interaction networks

    Longoni, M., Hansen, K. L., Russell, M. K., Loscertales, M., Abdul-Rahman, O. A., Baynam, G., Bleyl, S. B., Brady, P. D., Breckpot, J., Chen, C. P., Devriendt, K., Gillessen-Kaesbach, G., Grix, A. W., Rope, A. F., Shimokawa, O., Strauss, B., Wieczorek, D., Zackai, E. H., Coletti, C. M., Maalouf, F. I., Noonan, K. M., Park, J. H., Tracy, A. A., Lee, C., Donahoe, P. K. & Pober, B. R., Dec 2012, In : American Journal of Medical Genetics. Part A. 158A, 12, p. 3148-58 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  221. Published

    Looping in on Ndc80 - how does a protein loop at the kinetochore control chromosome segregation?

    Nilsson, Jakob, Dec 2012, In : BioEssays. 34, 12, p. 1070-7 8 p.

    Research output: Contribution to journalReviewResearchpeer-review

  222. Published

    SPOC1 modulates DNA repair by regulating key determinants of chromatin compaction and DNA damage response

    Mund, Andreas, Schubert, T., Staege, H., Kinkley, S., Reumann, K., Kriegs, M., Fritsch, L., Battisti, V., Ait-Si-Ali, S., Hoffbeck, A., Soutoglou, E. & Will, H., Dec 2012, In : Nucleic Acids Research. 40, 22, p. 11363-79 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  223. Published

    A Major Lineage of Enteroendocrine Cells Coexpress CCK, Secretin, GIP, GLP-1, PYY, and Neurotensin but Not Somatostatin

    Egerod, Kristoffer Lihme, Engelstoft, M. S., Grunddal, K. V., Nøhr, Mark Klitgaard, Secher, A., Sakata, I., Pedersen, J., Windeløv, Johanne Agerlin, Füchtbauer, E., Olsen, Jørgen, Sundler, F., Christensen, Jan Pravsgaard, Wierup, N., Olsen, Jesper Velgaard, Holst, Jens Juul, Zigman, J. M., Poulsen, Steen Seier & Schwartz, Thue W., 1 Dec 2012, In : Endocrinology. 153, 12, p. 5782-95 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  224. Published

    MiR-EdiTar: A database of predicted A-to-I edited miRNA target sites

    Laganà, A., Paone, A., Veneziano, D., Cascione, L., Gasparini, P., Carasi, S., Russo, Francesco, Nigita, G., MacCa, V., Giugno, R., Pulvirenti, A., Shasha, D., Ferro, A. & Croce, C. M., 1 Dec 2012, In : Bioinformatics. 28, 23, p. 3166-3168 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  225. Published

    Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3

    Sol, E. M., Wagner, S. A., Weinert, B. T., Kumar, A., Kim, H., Deng, C. & Choudhary, Chuna Ram, 7 Dec 2012, In : PloS one. 7, 12, p. e50545

    Research output: Contribution to journalJournal articleResearchpeer-review

  226. Published

    Dissecting molecular interactions involved in recognition of target disulfides by the barley thioredoxin system

    Björnberg, O., Maeda, K., Svensson, B. & Hägglund, Per Mårten, 11 Dec 2012, In : Biochemistry. 51, 49, p. 9930-9939 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  227. Published

    PheVI:09 (Phe6.44) as a sliding microswitch in seven-transmembrane (7TM) G protein-coupled receptor activation

    Valentin-Hansen, L., Holst, Birgitte, Frimurer, Thomas Michael, Schwartz, Thue W. & Hansen, L. V., 21 Dec 2012, In : Journal of Biological Chemistry. 287, 52, p. 43516-43526 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  228. 2013
  229. Published

    Common genomic signaling among initial DNA damage and radiation-induced apoptosis in peripheral blood lymphocytes from locally advanced breast cancer patients

    Henríquez-Hernández, L. A., Pinar, B., Carmona-Vigo, R., Bordón, E., Rodríguez-Gallego, C., Flores Morales, A. & Lara, P. C., 2013, In : Breast (Edinburgh, Scotland). 22, 1, p. 28-33 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  230. Published

    Effectiveness of a coordinated and tailored return-to-work intervention for sickness absence beneficiaries with mental health problems

    Martin, M., Nielsen, Michael Lund, Madsen, I., Petersen, S., Lange, Theis & Rugulies, R., 2013, In : Journal of Occupational Rehabilitation. 23, 4, p. 621-30 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  231. Published

    FBH1 co-operates with MUS81 in inducing DNA double-strand breaks and cell death following replication stress

    Fugger, K., Chu, W. K., Haahr, P., Kousholt, A. N., Beck, H., Payne, M. J., Hanada, K., Hickson, Ian David & Sørensen, Claus Storgaard, 2013, In : Nature Communications. 4, p. 1423

    Research output: Contribution to journalJournal articleResearchpeer-review

  232. Published

    ING1 induces apoptosis through direct effects at the mitochondria

    Bose, P., Thakur, S., Thalappilly, S., Ahn, B. Y., Satpathy, S., Feng, X., Suzuki, K., Kim, S. W. & Riabowol, K., 2013, In : Cell Death & Disease. 4, p. e788

    Research output: Contribution to journalJournal articleResearchpeer-review

  233. Published

    Novel serological neo-epitope markers of extracellular matrix proteins for the detection of portal hypertension

    Leeming, D. J., Karsdal, M. A., Byrjalsen, I., Bendtsen, Flemming, Trebicka, J., Nielsen, Michael Lund, Christiansen, C., Møller, Søren & Krag, A., 2013, In : Alimentary Pharmacology and Therapeutics. 38, 9, p. 1086-1096 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  234. Published

    RNA-DNA sequence differences spell genetic code ambiguities

    Bentin, Thomas & Nielsen, Michael Lund, 2013, In : Artificial DNA. 2, 3, p. 69-70 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  235. Published

    Self-assembly of designed coiled coil peptides studied by small-angle X-ray scattering and analytical ultracentrifugation

    Malik, L., Nygaard, J., Christensen, Niels Johan, Thulstrup, Peter Waaben, Arleth, Lise, Jensen, Knud Jørgen & Streicher, W., 2013, In : Journal of Peptide Science. 19, 5, p. 283-292 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  236. Published

    Systems biology approach identifies the kinase Csnk1a1 as a regulator of the DNA damage response in embryonic stem cells

    Carreras Puigvert, J., von Stechow, L., Siddappa, R., Pines, A., Bahjat, M., Haazen, L. C. J. M., Olsen, Jesper Velgaard, Vrieling, H., Meerman, J. H. N., Mullenders, L. H. F., van de Water, B. & Danen, E. H. J., 2013, In : Science Signaling. 6, 259, p. ra5 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  237. Published

    The SH2 domain interaction landscape

    Tinti, M., Kiemer, L., Costa, S., Miller, M. L., Sacco, F., Olsen, Jesper Velgaard, Carducci, M., Paoluzi, S., Langone, F., Workman, C., Blom, N., Machida, K., Thompson, C. M., Schutkowski, M., Brunak, Søren, Mann, Matthias, Mayer, B. J., Castagnoli, L. & Cesareni, G., 2013, In : Cell Reports. 3, 4, p. 1293-1305 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  238. Published

    Transcriptional intermediary factor 1γ binds to the anaphase-promoting complex/cyclosome and promotes mitosis

    Sedgwick, G. G., Townsend, K., Martin, A., Shimwell, N. J., Grand, R. J. A., Stewart, G. S., Nilsson, Jakob & Turnell, A. S., 2013, In : Oncogene. 32, 39, p. 4622-4633 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  239. Published

    Using guanidine-hydrochloride for fast and efficient protein digestion and single-step affinity-purification mass spectrometry

    Poulsen, J. W., Madsen, C. T., Young, C., Poulsen, F. M. & Nielsen, Michael Lund, 2013, In : Journal of Proteome Research. 12, 2, p. 1020-30 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  240. Published

    European guidelines for quality assurance in colorectal cancer screening and diagnosis: overview and introduction to the full supplement publication

    von Karsa, L., Patnick, J., Segnan, N., Atkin, W., Halloran, S., Lansdorp-Vogelaar, I., Malila, N., Minozzi, S., Moss, S., Quirke, P., Steele, R. J., Vieth, M., Aabakken, L., Altenhofen, L., Ancelle-Park, R., Antoljak, N., Anttila, A., Armaroli, P., Arrossi, S., Austoker, J., Banzi, R., Bellisario, C., Blom, J., Brenner, H., Bretthauer, M., Camargo Cancela, M., Costamagna, G., Cuzick, J., Dai, M., Daniel, J., Dekker, E., Delicata, N., Ducarroz, S., Erfkamp, H., Espinàs, J. A., Faivre, J., Faulds Wood, L., Flugelman, A., Frkovic-Grazio, S., Geller, B., Giordano, L., Grazzini, G., Green, J., Hamashima, C., Herrmann, C., Hewitson, P., Hoff, G., Holten, I., Jover, R., Lynge, Elsebeth & European Colorectal Cancer Screening Guidelines Working Group, E. C. C. S. G. W. G., 1 Jan 2013, In : Gastroenterological Endoscopy. 45, 1, p. 51-9 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  241. Published

    Quantification of the N-glycosylated secretome by super-SILAC during breast cancer progression and in human blood Samples

    Boersema, P. J., Geiger, T., Wiśniewski, J. R. & Mann, Matthias, 1 Jan 2013, In : Molecular & Cellular Proteomics. 12, 1, p. 158-171 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  242. Published

    Reply to 'Mining electronic health records: An additional perspective'

    Jensen, P. B., Jensen, Lars Juhl & Brunak, Søren, 1 Jan 2013, In : Nature Reviews. Genetics. 14, 1 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  243. Published

    STRING v9.1: Protein-protein interaction networks, with increased coverage and integration

    Franceschini, A., Simonovic, M., Roth, A., Von Mering, C., Szklarczyk, D., Pletscher-Frankild, S., Jensen, Lars Juhl, Kuhn, M. M., Lin, J., Minguez, P. & Bork, P., 1 Jan 2013, In : Nucleic Acids Research. 41, D1, p. D808-D815 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  244. Published

    Advances in characterizing ubiquitylation sites by mass spectrometry

    Sylvestersen, K. B., Young, C. & Nielsen, Michael Lund, 5 Jan 2013, In : Current Opinion in Chemical Biology. 17, 1, p. 49-58 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  245. Published

    To spread or not to spread - chromatin modifications in response to DNA damage

    Altmeyer, M. & Lukas, Jiri, 9 Jan 2013, In : Current Opinion in Genetics & Development. 23, 2, p. 156-165 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  246. Published

    Phosphorylation Variation during the Cell Cycle Scales with Structural Propensities of Proteins

    Tyanova, S., Frishman, D., Cox, J., Mann, Matthias & Olsen, Jesper Velgaard, 10 Jan 2013, In : P L o S Computational Biology (Online). 9, 1, p. e1002842 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  247. Published

    Direct binding between BubR1 and B56-PP2A phosphatase complexes regulate mitotic progression

    Kruse, Thomas, Zhang, G., Larsen, M. S. Y., Lischetti, T., Streicher, W., Nielsen, T. K., Bjørn, S. P. & Nilsson, Jakob, 23 Jan 2013, In : Journal of Cell Science. 126, p. 1086-1092 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  248. Published

    Mechanisms controlling the temporal degradation of Nek2A and Kif18A by the APC/C-Cdc20 complex

    Sedgwick, G. G., Hayward, D. G., Nilsson, Jakob, Di Fiore, B., Pines, J., Pardo, M. & Yu, L., 23 Jan 2013, In : E M B O Journal. 32, 2, p. 303-314 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  249. Published

    A Map of General and Specialized Chromatin Readers in Mouse Tissues Generated by Label-free Interaction Proteomics

    Eberl, H. C., Mann, M., Spruijt, C. G., Vermeulen, M. & Kelstrup, C. D., 24 Jan 2013, In : Molecular Cell. 49, 2, p. 368-378 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  250. Published

    A Small Molecule Inhibitor of the BLM Helicase Modulates Chromosome Stability in Human Cells

    Nguyen, G. H., Dexheimer, T. S., Rosenthal, A. S., Chu, W. K., Singh, D. K., Mosedale, G., Bachrati, C. Z., Schultz, L., Sakurai, M., Savitsky, P., Abu, M., McHugh, P. J., Bohr, Vilhelm, Harris, C. C., Jadhav, A., Gileadi, O., Maloney, D. J., Simeonov, A. & Hickson, Ian David, 24 Jan 2013, In : Chemistry & Biology. 20, 1, p. 55-62 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  251. Published

    Molecular determinants of subtype-selective efficacies of cytisine and the novel compound NS3861 at heteromeric nicotinic acetylcholine receptors

    Harpsøe, Kasper, Hald, H., Timmermann, D. B., Jensen, M. L., Dyhring, T., Nielsen, E. Ø., Peters, D., Balle, T., Gajhede, Michael, Kastrup, Jette Sandholm Jensen & Ahring, P. K., 25 Jan 2013, In : Journal of Biological Chemistry. 288, 4, p. 2559-2570 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  252. Published

    Molecular biology. Shielding broken DNA for a quick fix

    Lukas, Jiri & Lukas, Claudia, 8 Feb 2013, In : Science (New York, N.Y.). 339, 6120, p. 652-3 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  253. Published

    Shielding broken DNA for a quick fix

    Lukas, Jiri & Lukas, Claudia, 8 Feb 2013, In : Science. 339, 6120, p. 652-653 2 p.

    Research output: Contribution to journalReviewResearchpeer-review

  254. Published

    The 3rd DBCLS BioHackathon: improving life science data integration with semantic Web technologies

    Katayama, T., Wilkinson, M. D., Micklem, G., Kawashima, S., Yamaguchi, A., Nakao, M., Yamamoto, Y., Okamoto, S., Oouchida, K., Chun, H., Aerts, J., Afzal, H., Antezana, E., Arakawa, K., Aranda, B., Belleau, F., Bolleman, J., Bonnal, R. J., Chapman, B., Cock, P., Eriksson, T., Gordon, P., Goto, N., Hayashi, K., Horn, H., Ishiwata, R., Kaminuma, E., Kasprzyk, A., Kawaji, H., Kido, N., Kim, Y. J., Kinjo, A. R., Konishi, F., Kwon, K., Labarga, A., Lamprecht, A., Lin, Y., Lindenbaum, P., McCarthy, L., Morita, H., Murakami, K., Nagao, K., Nishida, K., Nishimura, K., Nishizawa, T., Ogishima, S., Ono, K., Oshita, K., Park, K., Prins, P., Saito, T. L., Samwald, M., Satagopam, V. P., Shigemoto, Y., Smith, R., Splendiani, A., Sugawara, H., Taylor, J., Vos, R., Withers, D., Yamasaki, C., Zmasek, C. M., Kawamoto, S., Okubo, K., Asai, K. & Takagi, T., 11 Feb 2013, In : Journal of Biomedical Semantics. 4, 1, p. 6 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  255. Published

    Poly(ADP-ribosyl)ation links the chromatin remodeler SMARCA5/SNF2H to RNF168-dependent DNA damage signaling

    Smeenk, G., Wiegant, W. W., Luijsterburg, M. S., Costelloe, T., Romeijn, R. J., Pastink, A., van Attikum, H., Marteijn, J. A., Vermeulen, W., Sroczynski, N. & Mailand, Niels, 15 Feb 2013, In : Journal of Cell Science. 126, 4, p. 889-903 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  256. Published

    In Vivo SILAC-Based Proteomics Reveals Phosphoproteome Changes during Mouse Skin Carcinogenesis

    Zanivan, S., Meves, A., Behrendt, K., Schoof, E., Neilson, L. J., Cox, J., Tang, H. R., Kalna, G., van Ree, J. H., van Deursen, J. M., Trempus, C. S., Machesky, L. M., Linding, R., Wickström, S. A., Fässler, R. & Mann, Matthias, 21 Feb 2013, In : Cell Reports. 3, 2, p. 552-566 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  257. Published

    The Coming Age of Complete, Accurate, and Ubiquitous Proteomes

    Mann, Matthias, Kulak, N. A., Nagaraj, N. & Cox, J., 21 Feb 2013, In : Molecular Cell. 49, 4, p. 583-590 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  258. Published

    RNF4 is required for DNA double-strand break repair in vivo

    Vyas, R., Kumar, R., Clermont, F., Helfricht, A., Kalev, P., Sotiropoulou, P., Hendriks, I. A., Radaelli, E., Hochepied, T., Blanpain, C., Sablina, A., van Attikum, H., Olsen, Jesper Velgaard, Jochemsen, A. G., Vertegaal, A. C. O. & Marine, J., Mar 2013, In : Cell Death and Differentiation. 20, 3, p. 490-502 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  259. Published

    RegulatING chromatin regulators: post-translational modification of the ING family of epigenetic regulators

    Satpathy, S., Nabbi, A. & Riabowol, K., 15 Mar 2013, In : Biochemical Journal. 450, 3, p. 433-42 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  260. Published

    Ubiquitin C-terminal hydrolase-L1 potentiates cancer chemosensitivity by stabilizing NOXA

    Brinkmann, K., Zigrino, P., Witt, A., Schell, M., Ackermann, Leena, Broxtermann, P., Schüll, S., Andree, M., Coutelle, O., Yazdanpanah, B., Seeger, J. M., Klubertz, D., Drebber, U., Hacker, U. T., Krönke, M., Mauch, C., Hoppe, T. & Kashkar, H., 28 Mar 2013, In : Cell Reports. 3, 3, p. 881-91 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  261. Published

    The Drosophila Microtubule-Associated Protein Mars Stabilizes Mitotic Spindles by Crosslinking Microtubules through Its N-Terminal Region

    Zhang, G., Beati, H., Nilsson, Jakob & Wodarz, A., 4 Apr 2013, In : P L o S One. 8, 4, p. e60596 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  262. Published

    Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders

    den Hoed, M., Eijgelsheim, M., Esko, T., Brundel, B. J. J. M., Peal, D. S., Evans, D. M., Nolte, I. M., Segrè, A. V., Holm, H., Handsaker, R. E., Westra, H., Johnson, T., Isaacs, A., Yang, J., Lundby, A., Zhao, J. H., Kim, Y. J., Go, M. J., Almgren, P., Bochud, M., Boucher, G., Cornelis, M. C., Gudbjartsson, D., Hadley, D., van der Harst, P., Hayward, C., den Heijer, M., Igl, W., Jackson, A. U., Kutalik, Z., Luan, J., Kemp, J. P., Kristiansson, K., Ladenvall, C., Lorentzon, M., Montasser, M. E., Njajou, O. T., O'Reilly, P. F., Padmanabhan, S., St Pourcain, B., Rankinen, T., Salo, P., Tanaka, T., Timpson, N. J., Vitart, V., Waite, L., Wheeler, W., Zhang, W., Draisma, H. H. M., Olsen, Jesper Velgaard & Global BPgen Consortium, G. B. C., 14 Apr 2013, In : Nature Genetics. 45, 6, p. 621-631 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  263. Published

    The deubiquitylating enzyme USP44 counteracts the DNA double-strand break response mediated by the RNF8 and RNF168 ubiquitin ligases

    Mosbech, A., Lukas, Claudia, Bekker-Jensen, Simon Holst & Mailand, Niels, 24 Apr 2013, In : Journal of Biological Chemistry. 288, p. 16579-16587 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  264. Published

    Systematic identification of proteins that elicit drug side effects

    Kuhn, M., Al Banchaabouchi, M., Campillos, M., Jensen, Lars Juhl, Gross, C., Gavin, A. & Bork, P., 30 Apr 2013, In : Molecular Systems Biology. 9, p. 663 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  265. Published

    Regulation of PCNA-protein interactions for genome stability

    Mailand, Niels, Gibbs-Seymour, I. & Bekker-Jensen, Simon Holst, May 2013, In : Nature Reviews. Molecular Cell Biology. 14, 5, p. 269-82 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  266. Published

    Mutations in FGF17, IL17RD, DUSP6, SPRY4, and FLRT3 are identified in individuals with congenital hypogonadotropic hypogonadism

    Miraoui, H., Dwyer, A. A., Hughes, V. A., Sidis, Y., Pitteloud, N., Sykiotis, G. P., Plummer, L., Feng, B., Keefe, K., Crowley Jr., W. F., Seminara, S. B., Hall, J. E., Chung, W., Tsai, P., Beenken, A., Mohammadi, M., Clarke, J., Rubenstein, J., Pers, T. H., Dworzynski, P., Hansen, K. L., Niedziela, M., Raivio, T., Quinton, R., Kumanov, P., Young, J. F., Yialamas, M. A., Van Vliet, G. & Chanoine, J., 2 May 2013, In : American Journal of Human Genetics. 92, 5, p. 725-743 19 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  267. Published

    The AID-induced DNA damage response in chromatin

    Daniel, J. A. & Nussenzweig, A., 9 May 2013, In : Molecular Cell. 50, 3, p. 309-21 13 p.

    Research output: Contribution to journalReviewResearchpeer-review

  268. Published

    ALKBH4-dependent demethylation of actin regulates actomyosin dynamics

    Li, M., Shi, Y., Niu, Y., Wu, Y., Huang, C., Jin, K., Lv, Y., Danielsen, J. M. R., Yang, Y., Nilsen, A., Fusser, M., Olofsson, M., Klungland, A., Ding, Y., Dong, M., Fu, Y., He, C., Liu, B. & Xu, X., 14 May 2013, In : Nature Communications. 4, 13 p., 1832.

    Research output: Contribution to journalJournal articleResearchpeer-review

  269. Published

    ADAM12 is expressed in the tumour vasculature and mediates ectodomain shedding of several membrane-anchored endothelial proteins

    Frohlich, C., Klitgaard, M., Noer, J. B., Kotzsch, A., Nehammer, C., Kronqvist, P., Berthelsen, J., Blobel, C., Kveiborg, Marie, Albrechtsen, Reidar & Wewer, Ulla M., 15 May 2013, In : Biochemical Journal. 452, 1, p. 97-109 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  270. Published

    Precision mapping of the human O-GalNAc glycoproteome through SimpleCell technology

    Steentoft, Catharina, Vakhrushev, Sergey, Joshi, Hiren Jitendra, Kong, Y., Vester-Christensen, M. B., Schjoldager, Katrine Ter-Borch Gram, Lavrsen, K., Dabelsteen, Sally, Pedersen, N. B., da Silva, L. P. M., Gupta, R., Bennett, Eric Paul, Mandel, Ulla, Brunak, Søren, Wandall, Hans H., Levery, S. B. & Clausen, Henrik, 15 May 2013, In : E M B O Journal. 32, 10, p. 1478-1488 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  271. Published

    Normalisation of left ventricular systolic function after change from VVI pacing to biventricular pacing in a child with congenital complete atrioventricular block, long-QT syndrome, and congenital muscular dystrophy: a 10-year follow-up

    Ellesøe, S. G., Reimers, J. I. & Andersen, H., 17 May 2013, In : Cardiology in the Young. 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  272. Published

    Dictionary construction and identification of possible adverse drug events in Danish clinical narrative text

    Eriksson, R., Jensen, P. B., Pletscher-Frankild, S., Jensen, Lars Juhl & Brunak, Søren, 23 May 2013, In : JAMIA - Journal of the American Medical Informatics Association. 20, 5, p. 947-953 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  273. Published

    Transcriptome profiling of mice testes following low dose irradiation

    Belling, Kirstine G, Nielsen, H. B., Brunak, Søren, Tanaka, M., Dalgaard, M. D., Nielsen, J. E., Almstrup, K. & Leffers, H., 28 May 2013, In : Reproductive Biology and Endocrinology. 11, 1, 13 p., 50.

    Research output: Contribution to journalJournal articleResearchpeer-review

  274. Published

    Acetylation dynamics of human nuclear proteins during the ionizing radiation-induced DNA damage response

    Bennetzen, M., Andersen, J. S., Lasen, D. H., Dinant, C., Watanabe, S., Bartek, J. & Lukas, Jiri, 1 Jun 2013, In : Cell Cycle. 12, 11, p. 1688-1695 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  275. Published

    Estrogens regulate the hepatic effects of growth hormone, a hormonal interplay with multiple fates

    Fernández-Pérez, L., Guerra, B., Díaz-Chico, J. C. & Flores Morales, A., 2 Jun 2013, In : Frontiers in Endocrinology. 4, 12 p., 66.

    Research output: Contribution to journalReviewResearchpeer-review

  276. Published

    In Vivo Phosphoproteomics Analysis Reveals the Cardiac Targets of β-Adrenergic Receptor Signaling

    Lundby, Alicia, Andersen, M. N., Steffensen, Annette Buur, Horn, H., Kelstrup, C. D., Francavilla, C., Jensen, Lars Juhl, Schmitt, Nicole, Thomsen, Morten Bækgaard & Olsen, Jesper Velgaard, 4 Jun 2013, In : Science Signaling. 6, 278, p. rs11 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  277. Published

    Structures of down syndrome kinases, DYRKs, reveal mechanisms of kinase activation and substrate recognition

    Soundararajan, M., Roos, A. K., Savitsky, P., Filippakopoulos, P., Kettenbach, A. N., Olsen, Jesper Velgaard, Gerber, S., Eswaran, J., Knapp, S. & Elkins, J. M., 4 Jun 2013, In : Structure. 21, 6, p. 986-996 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  278. Published

    iAnn: an event sharing platform for the life sciences

    Jimenez, R. C., Albar, J. P., Bhak, J., Blatter, M., Blicher, T., Brazas, M. D., Brooksbank, C., Budd, A., De Las Rivas, J., Dreyer, J., van Driel, M. A., Dunn, M. J., Fernandes, P. L., van Gelder, C. W. G., Hermjakob, H., Ioannidis, V., Judge, D. P., Kahlem, P., Korpelainen, E., Kraus, H., Loveland, J., Mayer, C., McDowall, J., Moran, F., Mulder, N., Nyronen, T., Rother, K., Salazar, G. A., Schneider, R., Via, A., Villaveces, J. M., Yu, P., Schneider, M. V., Attwood, T. K. & Corpas, M., 5 Jun 2013, In : Bioinformatics (Online). 29, 15, p. 1919-1921

    Research output: Contribution to journalJournal articleResearchpeer-review

  279. Published

    53BP1 mediates productive and mutagenic DNA repair through distinct phosphoprotein interactions

    Callen, E., Wong, N., Chen, H., Faryabi, R. B., Polato, F., Santos, M., Nussenzweig, A., Kruhlak, M. J., Di Virgilio, M., Nussenzweig, M. C., Nieto-Soler, M., Fernandez-Capetillo, O., Starnes, L. M., Daniel, J. A., Wesemann, D. R., Alt, F. W., Lee, J., Ge, K., Tubbs, A. & Sleckman, B. P., 6 Jun 2013, In : Cell. 153, 6, p. 1266-1280 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  280. Published

    OTULIN antagonizes LUBAC signaling by specifically hydrolyzing met1-linked polyubiquitin

    Keusekotten, K., Elliott, P. R., Kulathu, Y., Wauer, T., Hospenthal, M. K., Komander, D., Glockner, L., Krappmann, D., Fiil, B. K., Damgaard, R. B., Gyrd-Hansen, M. & Hofmann, K., 6 Jun 2013, In : Cell. 153, 6, p. 1312-1326 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  281. Published

    RNF111/Arkadia is a SUMO-targeted ubiquitin ligase that facilitates the DNA damage response

    Poulsen, S. L., Hansen, R. K., Wagner, S. A., van Cuijk, L., van Belle, G. J., Streicher, W., Wikström, M., Choudhary, Chuna Ram, Houtsmuller, A. B., Marteijn, J. A., Bekker-Jensen, Simon Holst & Mailand, Niels, 10 Jun 2013, In : Journal of Cell Biology. 201, 6, p. 797-807 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  282. Published

    The SPECIES and ORGANISMS Resources for Fast and Accurate Identification of Taxonomic Names in Text

    Pafilis, E., Pletscher-Frankild, S., Fanini, L., Faulwetter, S., Pavloudi, C., Vasileiadou, A., Arvanitidis, C. & Jensen, Lars Juhl, 18 Jun 2013, In : PloS one. 8, 6, p. e65390

    Research output: Contribution to journalJournal articleResearchpeer-review

  283. Published

    Guarding against Collateral Damage during Chromatin Transactions

    Altmeyer, M. & Lukas, Jiri, 20 Jun 2013, In : Cell. 153, 7, p. 1431-4 4 p.

    Research output: Contribution to journalReviewResearchpeer-review

  284. Published

    OTULIN Restricts Met1-Linked Ubiquitination to Control Innate Immune Signaling

    Fiil, B. K., Damgaard, R. B., Wagner, S. A., Keusekotten, K., Fritsch, M., Bekker-Jensen, Simon Holst, Mailand, Niels, Choudhary, Chuna Ram, Komander, D. & Gyrd-Hansen, M., 27 Jun 2013, In : Molecular Cell. 50, 6, p. 818-30 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  285. Published

    Prediction of disease causing non-synonymous SNPs by the Artificial Neural Network Predictor NetDiseaseSNP

    Johansen, M. B., Izarzugaza, J. M. G., Brunak, Søren, Petersen, T. N. & Gupta, R., Jul 2013, In : P L o S One. 8, 7, p. e68370

    Research output: Contribution to journalJournal articleResearchpeer-review

  286. Published

    Disease-causing mutations in the XIAP BIR2 domain impair NOD2-dependent immune signalling

    Damgaard, R. B., Fiil, B. K., Speckmann, C., Yabal, M., Stadt, U. Z., Bekker-Jensen, Simon Holst, Jost, P. J., Ehl, S., Mailand, Niels & Gyrd-Hansen, M., 1 Jul 2013, In : E M B O Journal. 5, p. 1278-1295 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  287. Published

    MetaRanker 2.0: a web server for prioritization of genetic variation data

    Pers, T. H., Dworzynski, P., Thomas, C. E., Hansen, K. L. & Brunak, Søren, 1 Jul 2013, In : Nucleic Acids Research. 41, W1, p. W104-W108

    Research output: Contribution to journalJournal articleResearchpeer-review

  288. Published

    Assessment and Challenges of Ligand Docking into Comparative Models of G-Protein Coupled Receptors

    Nguyen, E. D., Meiler, J., Norn, Christoffer & Frimurer, Thomas Michael, 2 Jul 2013, In : PLOS ONE. 8, 7, p. e67302 19 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  289. Published

    CDK-mediated activation of the SCF(FBXO) (28) ubiquitin ligase promotes MYC-driven transcription and tumourigenesis and predicts poor survival in breast cancer

    Cepeda, D., Ng, H., Sharifi, H. R., Mahmoudi, S., Cerrato, V. S., Fredlund, E., Magnusson, K., Nilsson, H., Malyukova, A., Rantala, J., Klevebring, D., Viñals, F., Bhaskaran, N., Zakaria, S. M., Rahmanto, A. S., Grotegut, S., Nielsen, Michael Lund, Szigyarto, C. A., Sun, D., Lerner, M., Navani, S., Widschwendter, M., Uhlén, M., Jirström, K., Pontén, F., Wohlschlegel, J., Grandér, D., Spruck, C., Larsson, L. & Sangfelt, O., 3 Jul 2013, In : E M B O Molecular Medicine (Online). 5, 7, p. 1067-1086 20 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  290. Published

    Recalibrating Equus evolution using the genome sequence of an early Middle Pleistocene horse

    Orlando, L. A. A., Ginolhac, A., Zhang, G., Froese, D., Albrechtsen, Anders, Stiller, M., Schubert, M., Cappellini, Enrico, Petersen, Bent, Moltke, Ida, Johnson, P. L. F., Fumagalli, M., Mouatt, J. T. V., Raghavan, M., Korneliussen, Thorfinn Sand, Malaspinas, A. S., Vogt, J., Szklarczyk, D. M., Kelstrup, C., Vinther, J., Dolocan, A., Stenderup, J., Velazquez, A. M. V., Cahill, J., Rasmussen, M., Wang, X., Min, J., Zazula, G. D., Seguin-Orlando, A., Mortensen, C., Magnussen, K., Thompson, J. F., Weinstock, J., Gregersen, K., Røed, K. H., Eisenmann, V., Rubin, C. J., Miller, D. C., Antczak, D. F., Bertelsen, M. F., Brunak, S., Al-Rasheid, K. A. S., Ryder, O., Andersson, L., Mundy, J., Krogh, Anders, Gilbert, M Thomas P, Kjær, Kurt H., Sicheritz-Pontén, T., Jensen, Lars Juhl, Olsen, Jesper Velgaard, Hofreiter, M., Nielsen, R., Shapiro, B., Wang, J. & Willerslev, Eske, 4 Jul 2013, In : Nature. 499, 7456, p. 74-78 5 p.

    Research output: Contribution to journalLetterResearchpeer-review

  291. Published

    Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli

    Weinert, B. T., Iesmantavicius, V., Wagner, S. A., Schölz, C., Gummesson, Bertil, Beli, P., Nyström, T. & Choudhary, Chuna Ram, 25 Jul 2013, In : Molecular Cell. 51, 2, p. 265-272 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  292. Published

    Facilitating the use of large-scale biological data and tools in the era of translational bioinformatics

    Kouskoumvekaki, I., Shublaq, N. & Brunak, Søren, 1 Aug 2013, In : Briefings in Bioinformatics. 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  293. Published

    Concordance of gene expression in human protein complexes reveals tissue specificity and pathology

    Börnigen, D., Pers, T. H., Thorrez, L., Huttenhower, C., Moreau, Y. & Brunak, Søren, 5 Aug 2013, In : Nucleic Acids Research. 41, 18, p. e171

    Research output: Contribution to journalJournal articleResearchpeer-review

  294. Published

    TIMP-1 increases expression and phosphorylation of proteins associated with drug resistance in breast cancer cells

    Hekmat, O., Munk, S., Fogh, L., Yadav, R., Francavilla, C., Horn, H., Würtz, S. Ø., Schrohl, A., Damsgaard, B., Romer, M. U., Belling, Kirstine G, Jensen, N. F., Gromova, I., Bekker-Jensen, D. B., Moreira, José, Jensen, Lars Juhl, Gupta, R., Lademann, U. A., Brünner, Nils, Olsen, Jesper Velgaard & Stenvang, Jan, 5 Aug 2013, In : Journal of Proteome Research. 12, 9, p. 4136-4151 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  295. Published

    Endogenous Nuclear RNAi Mediates Behavioral Adaptation to Odor

    Juang, B., Gu, C., Starnes, L., Palladino, F., Goga, A., Kennedy, S. & L'etoile, N. D., 29 Aug 2013, In : Cell. 154, 5, p. 1010-22 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  296. Published

    Lysine succinylation is a frequently occurring modification in prokaryotes and eukaryotes and extensively overlaps with acetylation

    Weinert, B. T., Schölz, C., Wagner, S. A., Iesmantavicius, V., Su, D., Daniel, J. A. & Choudhary, Chuna Ram, 29 Aug 2013, In : Cell Reports. 4, 4, p. 842-51 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  297. Published

    Best practices in bioinformatics training for life scientists

    Via, A., Blicher, T., Bongcam-Rudloff, E., Brazas, M. D., Brooksbank, C., Budd, A., De Las Rivas, J., Dreyer, J., Fernandes, P. L., van Gelder, C., Jacob, J., Jimenez, R. C., Loveland, J., Moran, F., Mulder, N., Nyrönen, T., Rother, K., Schneider, M. V. & Attwood, T. K., Sep 2013, In : Briefings in Bioinformatics. 14, 5, p. 528-37 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  298. Published

    Functional intersection of ATM and DNA-dependent protein kinase catalytic subunit in coding end joining during V(D)J recombination

    Lee, B., Gapud, E. J., Zhang, S., Dorsett, Y., Bredemeyer, A., George, R., Callen, E., Daniel, J. A., Osipovich, O., Oltz, E. M., Bassing, C. H., Nussenzweig, A., Lees-Miller, S., Hammel, M., Chen, B. P. C. & Sleckman, B. P., Sep 2013, In : Molecular and Cellular Biology. 33, 18, p. 3568-79 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  299. Published

    Phosphoproteomics taken to heart

    Lundby, Alicia & Olsen, Jesper Velgaard, 1 Sep 2013, In : Cell Cycle. 12, 17, p. 2707-2708 2 p.

    Research output: Contribution to journalEditorialResearchpeer-review

  300. Published

    Extracellular circulating viral microRNAs: Current knowledge and perspectives

    Laganà, A., Russo, Francesco, Veneziano, D., Bella, S. D., Giugno, R., Pulvirenti, A., Croce, C. M. & Ferro, A., 11 Sep 2013, In : Frontiers in Genetics. 4, JUN, Article 120.

    Research output: Contribution to journalReviewResearchpeer-review

  301. Published

    PICH: A DNA Translocase Specially Adapted for Processing Anaphase Bridge DNA

    Biebricher, A., Hirano, S., Enzlin, J., Wiechens, N., Streicher, W., Huttner, D., Wang, L., Nigg, E., Owen-Hughes, T., Liu, Ying, Peterman, E., Wuite, G. & Hickson, Ian David, 12 Sep 2013, In : Molecular Cell. 51, 5, p. 691-701 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  302. Published

    Covalent Trapping of Methyllycaconitine at the α4-α4 Interface of the α4β2 Nicotinic Acetylcholine Receptor: ANTAGONIST BINDING SITE AND MODE OF RECEPTOR INHIBITION REVEALED

    Absalom, N. L., Quek, G., Lewis, T. M., Qudah, T., von Arenstorff, I., Ambrus, J. I., Harpsøe, Kasper, Karim, N., Balle, T., McLeod, M. D. & Chebib, M., 13 Sep 2013, In : The Journal of Biological Chemistry. 288, 37, p. 26521-32 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  303. Published

    Genomic and proteomic analyses of Prdm5 reveal interactions with insulator binding proteins in embryonic stem cells

    Galli, G. G., Carrara, M., Francavilla, C., Honnens de Lichtenberg, Kristian, Olsen, Jesper Velgaard, Calogero, R. A. & Lund, Anders H., 16 Sep 2013, In : Molecular and Cellular Biology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  304. Published

    A computational approach to chemical etiologies of diabetes

    Audouze, K. M. L., Brunak, Søren & Grandjean, P., 19 Sep 2013, In : Scientific Reports. 3, p. 2712 2712.

    Research output: Contribution to journalJournal articleResearchpeer-review

  305. Published

    A nondegenerate code of deleterious variants in mendelian Loci contributes to complex disease risk

    Blair, D. R., Lyttle, C. S., Mortensen, J. M., Bearden, C. F., Jensen, A. B., Khiabanian, H., Melamed, R., Rabadan, R., Bernstam, E. V., Brunak, Søren, Jensen, Lars Juhl, Nicolae, D., Shah, N. H., Grossman, R. L., Cox, N. J., White, K. P. & Rzhetsky, A., 26 Sep 2013, In : Cell. 155, 1, p. 70-80 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  306. Published

    Functional Proteomics Defines the Molecular Switch Underlying FGF Receptor Trafficking and Cellular Outputs

    Francavilla, C., Rigbolt, K. T. G., Emdal, Kristina Bennet, Carraro, G., Vernet, E., Bekker-Jensen, D. B., Streicher, W., Wikström, M., Sundström, M., Bellusci, S., Cavallaro, U., Blagoev, B. & Olsen, Jesper Velgaard, 26 Sep 2013, In : Molecular Cell. 51, 6, p. 707-22 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  307. Published

    Small Angle X-Ray Scattering Studies of Mitochondrial Glutaminase C Reveal Extended Flexible Regions, and Link Oligomeric State with Enzyme Activity

    Møller, M., Nielsen, S. S., Ramachandran, S., Li, Y., Tria, G., Streicher, W., Petoukhov, M. V., Cerione, R. A., Gillilan, R. E. & Vestergaard, Bente, 30 Sep 2013, In : P L o S One. 8, 9, e74783.

    Research output: Contribution to journalJournal articleResearchpeer-review

  308. Published

    NetMHCIIpan-3.0, a common pan-specific MHC class II prediction method including all three human MHC class II isotypes, HLA-DR, HLA-DP and HLA-DQ

    Karosiene, E., Rasmussen, M., Blicher, T., Lund, O., Buus, Søren & Nielsen, M., Oct 2013, In : Immunogenetics. 65, 10, p. 711-24 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  309. Published

    X-linked inhibitor of apoptosis (XIAP) deficiency: The spectrum of presenting manifestations beyond hemophagocytic lymphohistiocytosis

    Speckmann, C., Lehmberg, K., Albert, M. H., Damgaard, R. B., Fritsch, M., Gyrd-Hansen, M., Rensing-Ehl, A., Vraetz, T., Grimbacher, B., Salzer, U., Fuchs, I., Ufheil, H., Belohradsky, B. H., Hassan, A., Cale, C. M., Elawad, M., Strahm, B., Schibli, S., Lauten, M., Kohl, M., Meerpohl, J. J., Rodeck, B., Kolb, R., Eberl, W., Soerensen, J., von Bernuth, H., Lorenz, M., Schwarz, K., zur Stadt, U. & Ehl, S., 1 Oct 2013, In : Clinical Immunology. 149, 1, p. 133-141 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  310. Published

    A new cellular stress response that triggers centriolar satellite reorganization and ciliogenesis

    Villumsen, B. H., Danielsen, J. R., Povlsen, L., Sylvestersen, K. B., Merdes, A., Beli, P., Yang, Y., Choudhary, Chuna Ram, Nielsen, Michael Lund, Mailand, Niels & Bekker-Jensen, Simon Holst, 11 Oct 2013, In : E M B O Journal. 32, 23, p. 3029-3040

    Research output: Contribution to journalJournal articleResearchpeer-review

  311. Published

    How unfinished business from S-phase affects mitosis and beyond

    Mankouri, H. W., Huttner, D. & Hickson, Ian David, 16 Oct 2013, In : EMBO Journal. 32, 20, p. 2661-71 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  312. Published

    Are graph databases ready for bioinformatics?

    Have, C. T. & Jensen, Lars Juhl, 21 Oct 2013, In : Bioinformatics (Online). 2 p.

    Research output: Contribution to journalEditorialResearch

  313. Published

    Proteome-wide Identification of Poly(ADP-Ribosyl)ation Targets in Different Genotoxic Stress Responses

    Jungmichel, S., Rosenthal, F., Altmeyer, M., Lukas, Jiri, Hottiger, M. O. & Nielsen, Michael Lund, 24 Oct 2013, In : Molecular Cell. 52, 2, p. 272-285 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  314. Published

    The Chromatin Scaffold Protein SAFB1 Renders Chromatin Permissive for DNA Damage Signaling

    Altmeyer, M., Toledo Lazaro, Luis Ignacio, Gudjónsson, Thorkell, Grøfte, M., Rask, M., Lukas, Claudia, Akimov, V., Blagoev, B., Bartek, J. & Lukas, Jiri, 24 Oct 2013, In : Molecular Cell. 52, 2, p. 206-220

    Research output: Contribution to journalJournal articleResearchpeer-review

  315. Published

    Status of large-scale analysis of post-translational modifications by mass spectrometry

    Olsen, Jesper Velgaard & Mann, Matthias, 1 Nov 2013, In : Molecular & Cellular Proteomics. 12, p. 3444-52

    Research output: Contribution to journalJournal articleResearchpeer-review

  316. Published

    The DNA damage checkpoint precedes activation of ARF in response to escalating oncogenic stress during tumorigenesis

    Evangelou, K., Bartkova, J., Kotsinas, A., Pateras, I. S., Liontos, M., Velimezi, G., Kosar, M., Liloglou, T., Trougakos, I. P., Dyrskjot, L., Andersen, C. L., Papaioannou, M., Drosos, Y., Papafotiou, G., Hodny, Z., Sosa-Pineda, B., Wu, X., Klinakis, A., Ørntoft, T. F., Lukas, Jiri, Bartek, J. & Gorgoulis, V. G., 1 Nov 2013, In : Cell Death and Differentiation. 20, 11, p. 1485-1497 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  317. Published

    The PI3-kinase isoform p110δ is essential for cell transformation induced by the D816V mutant of c-Kit in a lipid-kinase-independent manner

    Sun, J., Mohlin, S., Lundby, Alicia, Kazi, J. U., Hellman, U., Påhlman, S., Olsen, Jesper Velgaard & Rönnstrand, L., 11 Nov 2013, In : Oncogene.

    Research output: Contribution to journalJournal articleResearchpeer-review

  318. Published

    ATR-Chk1-APC/C-dependent stabilization of Cdc7-ASK (Dbf4) kinase is required for DNA lesion bypass under replication stress

    Yamada, M., Watanabe, K., Mistrik, M., Vesela, E., Protivankova, I., Mailand, Niels, Lee, M. H., Masai, H., Lukas, Jiri & Bartek, J., 15 Nov 2013, In : Genes & Development. 27, 22, p. 2459-2472 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  319. Published

    JMJD1C demethylates MDC1 to regulate the RNF8 and BRCA1-mediated chromatin response to DNA breaks

    Watanabe, S., Watanabe, K., Akimov, V., Bartkova, J., Blagoev, B., Lukas, Jiri & Bartek, J., 17 Nov 2013, In : Nature Structural and Molecular Biology. 20, p. 1425-1433

    Research output: Contribution to journalJournal articleResearchpeer-review

  320. Published

    ATR Prohibits Replication Catastrophe by Preventing Global Exhaustion of RPA

    Toledo Lazaro, Luis Ignacio, Altmeyer, M., Rask, M., Lukas, Claudia, Larsen, D. H., Povlsen, L. K., Bekker-Jensen, Simon Holst, Mailand, Niels, Bartek, J. & Lukas, Jiri, 21 Nov 2013, In : Cell. 155, 5, p. 1088-1103 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  321. Published

    STITCH 4: integration of protein-chemical interactions with user data

    Kuhn, M., Szklarczyk, D. M., Pletscher-Frankild, S., Blicher, T. H., von Mering, C., Jensen, Lars Juhl & Bork, P., 28 Nov 2013, In : Nucleic Acids Research. 42, D1, p. D401-D407 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  322. Published

    Heterologous expression and purification of an active human TRPV3 ion channel

    Kol, S., Braun, C. S., Thiel, G., Doyle, D. A., Sundström, M., Gourdon, Pontus Emanuel & Nissen, P., 1 Dec 2013, In : The F E B S Journal (Online). 280, 23, p. 6010-6021 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  323. Published

    eggNOG v4.0: nested orthology inference across 3686 organisms

    Powell, S., Forslund, K., Szklarczyk, D. M., Trachana, K., Roth, A., Huerta-Cepas, J., Gabaldón, T., Rattei, T., Creevey, C., Kuhn, M., Jensen, Lars Juhl, von Mering, C. & Bork, P., 1 Dec 2013, In : Nucleic Acids Research. 42, D1, p. D231-D239 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  324. Published

    A minimal number of MELT repeats supports all functions of KNL1 in chromosome segregation

    Zhang, G., Lischetti, T. & Nilsson, Jakob, 20 Dec 2013, In : Journal of Cell Science. 127, p. 871-884

    Research output: Contribution to journalJournal articleResearchpeer-review

  325. 2014
  326. Published

    A comparison of protein kinases inhibitor screening methods using both enzymatic activity and binding affinity determination

    Rudolf, A. F., Skovgaard, T., Knapp, S., Jensen, Lars Juhl & Berthelsen, J., 2014, In : PloS one. 9, 6, p. 1-5 6 p., e98800.

    Research output: Contribution to journalJournal articleResearchpeer-review

  327. Published

    A genome-wide association study identifies CDHR3 as a susceptibility locus for early childhood asthma with severe exacerbations

    Bønnelykke, K., Sleiman, P., Nielsen, K., Kreiner-Møller, E., Mercader, J. M., Belgrave, D., den Dekker, H. T., Husby, A., Sevelsted, A., Faura-Tellez, G., Paternoster, L., Flaaten, R., Mølgaard, A., Smart, D. E., Thomsen, P. F., Rasmussen, Morten Arendt, Bonàs-Guarch, S., Holst, C., Nohr, E. A., Yadav, R., March, M. E., Blicher, T. H., Lackie, P. M., Jaddoe, V. W. V., Simpson, A., Holloway, J. W., Duijts, L., Custovic, A., Davies, D. E., Torrents, D., Gupta, R., Hollegaard, M. V., Hougaard, D. M., Hakonarson, H. & Bisgaard, Hans, 2014, In : Nature Genetics. 46, p. 51-55 5 p.

    Research output: Contribution to journalLetterResearchpeer-review

  328. Published

    Analogues of the natural product Sinefungin as inhibitors of EHMT1 and EHMT2

    Devkota, K., Lohse, Brian, Liu, Q., Wang, M., Stærk, Dan, Berthelsen, J. & Clausen, Rasmus Prætorius, 2014, In : A C S Medicinal Chemistry Letters. 5, 4, p. 293-297

    Research output: Contribution to journalLetterResearchpeer-review

  329. Published

    COMPARTMENTS: unification and visualization of protein subcellular localization evidence

    Binder, J. X., Pletscher-Frankild, S., Tsafou, K., Stolte, C., O'Donoghue, S. I., Schneider, R. & Jensen, Lars Juhl, 2014, In : Database. 2014, 9 p., bau012.

    Research output: Contribution to journalJournal articleResearchpeer-review

  330. Published

    Development of a native Escherichia coli induction system for ionic liquid tolerance

    Frederix, M., Hütter, K., Leu, J., Batth, Tanveer Singh, Turner, W. J., Rüegg, T. L., Blanch, H. W., Simmons, B. A., Adams, P. D., Keasling, J. D., Thelen, M. P., Dunlop, M. J., Petzold, C. J. & Mukhopadhyay, A., 2014, In : PLOS ONE. 9, 7, p. e101115

    Research output: Contribution to journalJournal articleResearchpeer-review

  331. Published

    Direct evidence of milk consumption from ancient human dental calculus

    Warinner, C., Hendy, J., Speller, C., Cappellini, Enrico, Fischer, R., Trachsel, C., Arneborg, J., Lynnerup, Niels, Craig, O. E., Swallow, D. M., Fotaki, Anna Katerina, Jersie-Christensen, R. R., Olsen, Jesper Velgaard, Liebert, A., Montalva, N., Fiddyment, S., Charlton, S., Mackie, Meaghan, Canci, A., Bouwman, A., Rühli, F., Gilbert, M Thomas P & Collins, M. J., 2014, In : Scientific Reports. 4, 6 p., 7104.

    Research output: Contribution to journalJournal articleResearchpeer-review

  332. Published

    Discrepancies in listed adverse drug reactions in pharmaceutical product information supplied by the regulatory authorities in Denmark and the USA

    Eriksson, Robert, Aagaard, L., Jensen, Lars Juhl, Borisova, L., Hørlück, D., Brunak, Søren & Hansen, E. H., 2014, In : Pharmacology Research & Perspectives. 2, 3, p. 1-10 e00038.

    Research output: Contribution to journalJournal articleResearchpeer-review

  333. Published

    Helical propensity in an intrinsically disordered protein accelerates ligand binding

    Iesmantavicius, V., Dogan, J., Jemth, P., Teilum, Kaare & Kjærgaard, Magnus, 2014, In : Angewandte Chemie (International ed. in English). 53, 6, p. 1548-1551 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  334. Published

    Human chitotriosidase CHIT1 cross reacts with mammalian-like substrates

    Larsen, T., Yoshimura, Y., Voldborg, B. G. R., Cazzamali, G., Bovin, N. V., Westerlind, U., Palcic, M. M. & Leisner, Jørgen, 2014, In : F E B S Letters. 588, 5, p. 746-751 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  335. Published

    Identification of thioredoxin target disulfides using isotope-coded affinity tags

    Hägglund, Per Mårten, Bunkenborg, J., Maeda, K., Finnie, C. & Svensson, B., 2014, Plant Proteomics: Methods and Protocols. Humana Press, p. 677-685 9 p. (Methods in Molecular Biology, Vol. 1072).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  336. Published

    Lipid profiling and transcriptomic analysis reveals a functional interplay between estradiol and growth hormone in liver

    Fernández-Pérez, L., Santana-Farré, R., Mirecki-Garrido, M. D., García, I., Guerra, B., Mateo-Diaz, C., Iglesias Gato, Diego, Díaz-Chico, J. C., Flores Morales, A. & Díaz, M., 2014, In : P L o S One. 9, 19 p., e96305.

    Research output: Contribution to journalJournal articleResearchpeer-review

  337. Published

    Molecular basis and regulation of OTULIN-LUBAC interaction

    Elliott, P. R., Nielsen, Sofie Vincents, Marco-Casanova, P., Fiil, B. K., Keusekotten, K., Mailand, Niels, Freund, S. M. V., Gyrd-Hansen, M. & Komander, D., 2014, In : Molecular Cell. 54, 3, p. 335-348 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  338. Published

    Pathogens and host immunity in the ancient human oral cavity

    Warinner, C., Rodrigues, J. F. M., Vyas, R., Trachsel, C., Shved, N., Grossmann, J., Radini, A., Hancock, Y., Tito, R. Y., Fiddyment, S., Speller, C., Hendy, J., Charlton, S., Luder, H. U., Salazar-García, D. C., Eppler, E., Seiler, R., Hansen, Lars Hestbjerg, Samaniego Castruita, J. A., Barkow-Oesterreicher, S., Teoh, K. Y., Kelstrup, C., Olsen, Jesper Velgaard, Nanni, P., Kawai, T., Willerslev, Eske, von Mering, C., Lewis, C. M., Collins, M. J., Gilbert, M Thomas P, Rühli, F. & Cappellini, Enrico, 2014, In : Nature Genetics. 46, p. 336-344 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  339. Published

    Predicting Kinase Activity in Angiotensin Receptor Phosphoproteomes Based on Sequence-Motifs and Interactions

    Bøgebo, R., Horn, H., Olsen, Jesper Velgaard, Gammeltoft, S., Jensen, Lars Juhl, Hansen, J. L. & Christensen, G. L., 2014, In : PLOS ONE. 9, 4, p. 1-9 9 p., e94672.

    Research output: Contribution to journalJournal articleResearchpeer-review

  340. Published

    Protein-driven inference of miRNA-disease associations

    Mørk, S., Pletscher-Frankild, S., Palleja, A., Gorodkin, Jan & Jensen, Lars Juhl, 2014, In : Bioinformatics (Oxford, England). 30, 3, p. 392-397 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  341. Published

    REST mediates androgen receptor actions on gene repression and predicts early recurrence of prostate cancer

    Svensson, C., Ceder, J., Iglesias Gato, Diego, Chuan, Y. C., Pang, S. T., Bjartell, A., Martinez, R. M., Bott, L., Helczynski, L., Ulmert, D., Wang, Y., Niu, Y., Collins, C. & Flores Morales, A., 2014, In : Nucleic Acids Research. 42, 2, p. 999-1015 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  342. Published

    Resolution of the type material of the Asian elephant, Elephas maximus Linnaeus, 1758 (Proboscidea, Elephantidae)

    Cappellini, Enrico, Gentry, A., Palkopoulou, E., Ishida, Y., Cram, D., Roos, A., Watson, M., Johansson, U. S., Fernholm, B., Agnelli, P., Barbagli, F., Littlewood, D. T. J., Kelstrup, C., Olsen, Jesper Velgaard, Lister, A. M., Roca, A. L., Dalén, L. & Gilbert, M Thomas P, 2014, In : Zoological Journal of the Linnean Society. 170, 1, p. 222-232 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  343. Published

    SOCS proteins in regulation of receptor tyrosine kinase signaling

    Kazi, J. U., Kabir, N. N., Flores Morales, A. & Rönnstrand, L., 2014, In : Cellular and Molecular Life Sciences. 71, 17, p. 3297-3310 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  344. Published

    SOCS2 mediates the cross talk between androgen and growth hormone signaling in prostate cancer

    Iglesias Gato, Diego, Chuan, Y. C., Wikström, P., Augsten, S., Jiang, N., Niu, Y., Seipel, A., Danneman, D., Vermeij, M., Fernandez-Perez, L., Jenster, G., Egevad, L., Norstedt, G. & Flores Morales, A., 2014, In : Carcinogenesis. 35, 1, p. 24-33

    Research output: Contribution to journalJournal articleResearchpeer-review

  345. Published

    Semantic Relation Discovery by using Co-occurrence Information

    Schulz, S., Catalina, M. C., Kreuzthaler, M., Minarro-Gimenez, J. A., Andersen, U., Jensen, A. B. & Maegaard, Bente, 2014. 6 p.

    Research output: Contribution to conferencePaperResearchpeer-review

  346. Published

    Species identification of archaeological skin objects from Danish bogs: comparison between mass spectrometry-based peptide sequencing and microscopy-based methods

    Brandt, Luise Ørsted, Schmidt, A. L., Mannering, U., Sarret, M., Kelstrup, C., Olsen, Jesper Velgaard & Cappellini, Enrico, 2014, In : PloS one. 9, 9, 10 p., e106875.

    Research output: Contribution to journalJournal articleResearchpeer-review

  347. Published

    Systematic Analysis of the Crosstalk between Mitosis and DNA Damage by a Live Cell siRNA Screen

    Pedersen, R. S., 2014, Faculty of Science, University of Copenhagen. 143 p.

    Research output: Book/ReportPh.D. thesisResearch

  348. Published

    The impact of structural integrity and route of administration on the antibody specificity against three cow's milk allergens - a study in Brown Norway rats

    Madsen, J. L., Kroghsbo, S., Madsen, C. B., Pozdnyakova, I., Barkholt, V. & Bøgh, K. L., 2014, In : Clinical and Translational Allergy. 4, 12 p., 25.

    Research output: Contribution to journalJournal articleResearchpeer-review

  349. Published

    The use of combined heart rate response and accelerometry to assess the level and predictors of physical activity in tuberculosis patients in Tanzania

    Faurholt-Jepsen, M., Faurholt-Jepsen, D., Range, N., Praygod, G., Jeremiah, K., Aabye, M. G., Changalucha, J., Krarup, H., Christensen, Dirk Lund, Andersen, A. B., Brage, S. & Friis, Henrik, 2014, In : Epidemiology and Infection. 142, 6, p. 1334-1342 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  350. Published

    Tousled-like kinases phosphorylate Asf1 to promote histone supply during DNA replication

    Kamalyukova, I. M., Young, C., Strømme, C. B., Ménard, Patrice, Jasencakova, Zuzana, Mejlvang, J., Ask, K., Ploug, Michael, Nielsen, Michael Lund, Jensen, O. N. & Groth, Anja, 2014, In : Nature Communications. 5, p. 3394

    Research output: Contribution to journalJournal articleResearchpeer-review

  351. Published

    UBL5 is essential for pre-mRNA splicing and sister chromatid cohesion in human cells

    Oka, Y., Varmark, H., Vitting-Seerup, Kristoffer, Beli, P., Waage, J. E., Hakobyan, A., Mistrik, M., Choudhary, Chuna Ram, Rohde, M., Bekker-Jensen, Simon Holst & Mailand, Niels, 2014, In : E M B O Reports. 15, 9, p. 956-964 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  352. Published

    Create and preserve: proteostasis in development and aging is governed by Cdc48/p97/VCP

    Franz, A., Ackermann, Leena & Hoppe, T., Jan 2014, In : B B A - Reviews on Cancer. 1843, 1, p. 205-15 11 p.

    Research output: Contribution to journalReviewResearchpeer-review

  353. Published

    A knowledge base for the discovery of function, diagnostic potential and drug effects on cellular and extracellular miRNAs

    Russo, Francesco, Di Bella, S., Bonnici, V., Laganà, A., Rainaldi, G., Pellegrini, M., Pulvirenti, A., Giugno, R. & Ferro, A., 1 Jan 2014, In : BMC Genomics. 15, S4.

    Research output: Contribution to journalJournal articleResearchpeer-review

  354. Published

    BuD, a helix-loop-helix DNA-binding domain for genome modification

    Stella, Stefano, Molina, Rafael, López-Méndez, B., Juillerat, A., Bertonati, C., Daboussi, F., Campos-Olivas, R., Duchateau, P. & Montoya, Guillermo, 1 Jan 2014, In : Acta Crystallographica Section D: Biological Crystallography. 70, 7, p. 2042-2052 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  355. Published

    Comprehensive reconstruction and visualization of non-coding regulatory networks in human

    Bonnici, V., Russo, Francesco, Bombieri, N., Pulvirenti, A. & Giugno, R., 1 Jan 2014, In : Frontiers in Bioengineering and Biotechnology. 2, DEC, 69.

    Research output: Contribution to journalJournal articleResearchpeer-review

  356. Published

    Expression, purification, crystallization and preliminary X-ray diffraction analysis of the novel modular DNA-binding protein BurrH in its apo form and in complex with its target DNA

    Stella, Stefano, Molina, Rafael, Bertonatti, C., Juillerrat, A. & Montoya, Guillermo, 1 Jan 2014, In : Acta Crystallographica Section F:Structural Biology Communications. 70, 1, p. 87-91 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  357. Published

    Numb-dependent integration of pre-TCR and p53 function in T-cell precursor development

    Martin-Blanco, N. M., Checquolo, S., Del Gaudio, F., Palermo, R., Franciosa, Giulia, Di Marcotullio, L., Gulino, A., Canelles, M. & Screpanti, I., 1 Jan 2014, In : Cell Death and Disease. 5, e1472.

    Research output: Contribution to journalJournal articleResearchpeer-review

  358. Published

    Purification, characterization and crystallization of the human 80S ribosome

    Khatter, H., Myasnikov, A. G., Mastio, L., Billas, I. M. L., Birck, C., Stella, Stefano & Klaholz, B. P., 1 Jan 2014, In : Nucleic Acids Research. 42, 6

    Research output: Contribution to journalJournal articleResearchpeer-review

  359. Published

    New histone supply regulates replication fork speed and PCNA unloading

    Mejlvang, J., Feng, Y., Alabert, C., Neelsen, K. J., Jasencakova, Zuzana, Zhao, X., Lees, M., Sandelin, Albin Gustav, Pasero, P., Lopes, M. & Groth, Anja, 6 Jan 2014, In : Journal of Cell Biology. 204, 1, p. 29-43 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  360. Published

    Glutamine methylation in histone H2A is an RNA-polymerase-I-dedicated modification

    Tessarz, P., Santos-Rosa, H., Robson, S. C., Sylvestersen, K. B., Nelson, C. J., Nielsen, Michael Lund & Kouzarides, T., 23 Jan 2014, In : Nature. 505, p. 564-568

    Research output: Contribution to journalJournal articleResearchpeer-review

  361. Published

    Protein Interaction Screening for the Ankyrin Repeats and Suppressor of Cytokine Signaling (SOCS) Box (ASB) Family Identify Asb11 as a Novel Endoplasmic Reticulum Resident Ubiquitin Ligase

    Andresen, C. A., Smedegaard, S., Sylvestersen, K. B., Svensson, C., Iglesias Gato, Diego, Cazzamali, G., Nielsen, T. K., Nielsen, Michael Lund & Flores Morales, A., 24 Jan 2014, In : The Journal of Biological Chemistry. 289, 4, p. 2043-2054 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  362. Published

    Stable MCC binding to the APC/C is required for a functional spindle assembly checkpoint

    bmk286, bmk286 & Nilsson, Jakob, 25 Jan 2014, In : E M B O Reports. 15, p. 264-272

    Research output: Contribution to journalJournal articleResearchpeer-review

  363. Published

    A direct role of Mad1 in the spindle assembly checkpoint beyond Mad2 kinetochore recruitment

    Kruse, Thomas, Larsen, M. S. Y., Sedgwick, G. G., Sigurdsson, J. O., Streicher, W., Olsen, Jesper Velgaard & Nilsson, Jakob, 29 Jan 2014, In : E M B O Reports. 15, p. 282-290

    Research output: Contribution to journalJournal articleResearchpeer-review

  364. Published

    Acetylation dynamics and stoichiometry in Saccharomyces cerevisiae

    Weinert, B. T., Iesmantavicius, V., Moustafa, T., Schölz, C., Wagner, S. A., Magnes, C., Zechner, R. & Choudhary, Chuna Ram, 31 Jan 2014, In : Molecular Systems Biology. 10, 1, p. 716 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  365. Published

    Compass: A hybrid method for clinical and biobank data mining

    Krysiak-Baltyn, K., Nordahl Petersen, T., Audouze, K. M. L., Jørgensen, N., Ängquist, Lars & Brunak, Søren, Feb 2014, In : Journal of Biomedical Informatics. 47, p. 160-170

    Research output: Contribution to journalJournal articleResearchpeer-review

  366. Published

    Crystallization and preliminary X-ray diffraction analysis of the homing endonuclease I-CvuI from Chlorella vulgaris in complex with its target DNA

    Redondo, P., Merino, N., Villate, M., Blanco, F. J., Montoya, Guillermo & Molina, Rafael, Feb 2014, In : Acta crystallographica. Section F, Structural biology communications. 70, Pt 2, p. 256-9 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  367. Published

    Redox-active quinones induces genome-wide DNA methylation changes by an iron-mediated and Tet-dependent mechanism

    Zhao, B., Yang, Y., Wang, X., Chong, Z., Yin, R., Song, S., Zhao, C., Li, C., Huang, H., Sun, B., Wu, D., Jin, K., Song, M., Zhu, B., Jiang, G., Danielsen, J. M. R., Xu, G., Yang, Y. & Wang, H., Feb 2014, In : Nucleic Acids Research. 42, 3, p. 1593-1605 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  368. Published

    Gibberellic acid-induced aleurone layers responding to heat shock or tunicamycin provide insight into the N-glycoproteome, protein secretion, and endoplasmic reticulum stress

    Barba-Espín, G., Dedvisitsakul, P., Hägglund, Per Mårten, Svensson, B. & Finnie, C., 1 Feb 2014, In : Plant Physiology. 164, 2, p. 951-965 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  369. Published

    Cofactory: Sequence-based prediction of cofactor specificity of Rossmann folds

    Geertz-Hansen, H. M., Blom, N., Feist, A., Brunak, Søren & Petersen, T. N., 13 Feb 2014, In : Proteins: Structure, Function, and Bioinformatics. 82, 9, p. 1819-1828 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  370. Published

    Specificity and commonality of the phosphoinositide-binding proteome analyzed by quantitative mass spectrometry

    Jungmichel, S., Sylvestersen, K. B., Choudhary, Chuna Ram, Nguyen, S., Mann, Matthias & Nielsen, Michael Lund, 13 Feb 2014, In : Cell Reports. 6, 3, p. 578-91 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  371. Published

    Proteomic analysis of arginine methylation sites in human cells reveals dynamic regulation during transcriptional arrest

    Sylvestersen, K. B., Horn, H., Jungmichel, S., Jensen, Lars Juhl & Nielsen, Michael Lund, 21 Feb 2014, In : Molecular & Cellular Proteomics. 13, p. 2072-2088 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  372. Published

    Citrullination regulates pluripotency and histone H1 binding to chromatin

    Christophorou, M. A., Castelo-Branco, G., Halley-Stott, R. P., Oliveira, C. S., Loos, R., Radzisheuskaya, A., Mowen, K. A., Bertone, P., Silva, J. C. R., Zernicka-Goetz, M., Nielsen, Michael Lund, Gurdon, J. B. & Kouzarides, T., 6 Mar 2014, In : Nature. 507, p. 104-108

    Research output: Contribution to journalJournal articleResearchpeer-review

  373. Published

    DoReMi: context-based prioritization of linear motif matches

    Horn, H., Haslam, N. & Jensen, Lars Juhl, 20 Mar 2014, In : PeerJ. 2, 10 p., e315.

    Research output: Contribution to journalJournal articleResearchpeer-review

  374. Published

    Uncovering SUMOylation Dynamics during Cell-Cycle Progression Reveals FoxM1 as a Key Mitotic SUMO Target Protein

    Schimmel, J., Eifler, K., Sigurdsson, J. O., Cuijpers, S. A. G., Hendriks, I. A., Verlaan-de Vries, M., Kelstrup, C. D., Francavilla, C., Medema, R. H., Olsen, Jesper Velgaard & Vertegaal, A. C. O., 20 Mar 2014, In : Molecular Cell. 53, 6, p. 1053-1066

    Research output: Contribution to journalJournal articleResearchpeer-review

  375. Published

    Comprehensive analysis of the specificity of transcription activator-like effector nucleases

    Juillerat, A., Dubois, G., Valton, J., Thomas, S., Stella, Stefano, Maréchal, A., Langevin, S., Benomari, N., Bertonati, C., Silva, G. H., Daboussi, F., Epinat, J., Montoya, Guillermo, Duclert, A. & Duchateau, P., Apr 2014, In : Nucleic Acids Research. 42, 8, p. 5390-402 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  376. Published

    Dose-specific adverse drug reaction identification in electronic patient records: temporal data mining in an inpatient psychiatric population

    Eriksson, Robert, Werge, T., Jensen, Lars Juhl & Brunak, Søren, Apr 2014, In : Drug Safety. 37, 4, p. 237-47 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  377. Published

    The role of extracellular matrix quality in pulmonary fibrosis

    Kristensen, J. H., Karsdal, M. A., Genovese, F., Johnson, S., Svensson, B., Jacobsen, S., Hägglund, Per Mårten & Leeming, D. J., 14 Apr 2014, In : Respiration. 88, 6, p. 487-499 13 p.

    Research output: Contribution to journalReviewResearchpeer-review

  378. Published

    qcML: an exchange format for quality control metrics from mass spectrometry experiments

    Walzer, M., Pernas, L. E., Nasso, S., Bittremieux, W., Nahnsen, S., Kelchtermans, P., Pichler, P., van den Toorn, H. W. P., Staes, A., Vandenbussche, J., Mazanek, M., Taus, T., Scheltema, R. A., Kelstrup, C. D., Gatto, L., van Breukelen, B., Aiche, S., Valkenborg, D., Laukens, K., Lilley, K. S., Olsen, Jesper Velgaard, Heck, A. J. R., Mechtler, K., Aebersold, R., Gevaert, K., Vizcaino, J. A., Hermjakob, H., Kohlbacher, O. & Martens, L., 23 Apr 2014, In : Molecular & Cellular Proteomics. 13, 8, p. 1905-1913 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  379. Published

    Ago2 facilitates Rad51 recruitment and DNA double-strand break repair by homologous recombination

    Gao, M., Wei, W., Li, M. H., Wu, Y., Ba, Z., Jin, K., Li, M., Liao, Y., Adhikari, S., Chong, Z., Zhang, T., Guo, C., Tang, T., Zhu, B., Xu, X., Mailand, Niels, Yang, Y., Qi, Y. & Danielsen, J. M. R., May 2014, In : Cell Research. 24, 5, p. 532-41 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  380. Published

    Erratum to: Dose-Specific Adverse Drug Reaction Identification in Electronic Patient Records: Temporal Data Mining in an Inpatient Psychiatric Population

    Eriksson, Robert, Werge, T., Jensen, Lars Juhl & Brunak, Søren, May 2014, In : Drug Safety. 37, 5, p. 379

    Research output: Contribution to journalJournal articleResearchpeer-review

  381. Published

    A substrate-optimized electrophoretic mobility shift assay for ADAM12

    Kotzsch, A., Skovgaard, T., Buus, U., Andersen, S., Devkota, K. & Berthelsen, J., 1 May 2014, In : Analytical Biochemistry. 452, p. 34-42 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  382. Published

    Glycopeptide enrichment using a combination of ZIC-HILIC and cotton wool for exploring the glycoproteome of wheat flour albumins

    Dedvisitsakul, P., Jacobsen, S., Svensson, B., Bunkenborg, J., Finnie, C. & Hägglund, Per Mårten, 2 May 2014, In : Journal of Proteome Research. 13, 5, p. 2696-2703 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  383. Published

    Functional and Structural Properties of a Novel Protein and Virulence Factor (sHIP) in Streptococcus pyogenes

    Wisniewska, M., Happonen, L., Kahn, F., Varjosalo, M., Malmström, L., Rosenberger, G., Karlsson, C., Cazzamali, G., Pozdnyakova, I., Frick, I., Björck, L., Streicher, W., Malmström, J. & Wikström, M., 13 May 2014, In : The Journal of Biological Chemistry. 289, p. 18175-18188

    Research output: Contribution to journalJournal articleResearchpeer-review

  384. Published

    KinomeXplorer: an integrated platform for kinome biology studies

    Horn, H., Schoof, E. M., Kim, J., Robin, X., Miller, M. L., Diella, F., Palma, A., Cesareni, G., Jensen, Lars Juhl & Linding, R., 29 May 2014, In : Nature Methods. 11, 6, p. 603-4 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  385. Published

    A complement to the modern crystallographer's toolbox: caged gadolinium complexes with versatile binding modes

    Stelter, M., Molina, Rafael, Jeudy, S., Kahn, R., Abergel, C. & Hermoso, J. A., Jun 2014, In : Acta crystallographica. Section D, Biological crystallography. 70, Pt 6, p. 1506-16 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  386. Published

    Analytical utility of mass spectral binning in proteomic experiments by SPectral Immonium Ion Detection (SPIID)

    Kelstrup, C. D., Freese, C., Heck, A. J. R., Olsen, Jesper Velgaard & Nielsen, Michael Lund, 3 Jun 2014, In : Molecular & Cellular Proteomics. 13, 8, p. 1914-1924 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  387. Published

    Biochemical characterization of human gluconokinase and the proposed metabolic impact of gluconic Acid as determined by constraint based metabolic network analysis

    Rohatgi, N., Nielsen, T. K., Bjørn, S. P., Axelsson, I., Paglia, G., Voldborg, B. G., Palsson, B. O. & Rolfsson, O., 4 Jun 2014, In : PloS one. 9, 6, 9 p., e98760.

    Research output: Contribution to journalJournal articleResearchpeer-review

  388. Published

    B-lymphoid tyrosine kinase (Blk) is an oncogene and a potential target for therapy with Dasatinib in cutaneous T-cell lymphoma (CTCL)

    Petersen, David Leander, Krejsgaard, Thorbjørn Frej, Berthelsen, J., Fredholm, S., Willerslev-Olsen, Andreas, Sibbesen, N. A., Bonefeld, Charlotte Menne, Andersen, M. H., Francavilla, C., Olsen, Jesper Velgaard, Hu, T., Zhang, M., Wasik, M. A., Geisler, Carsten, Woetmann, Anders & Ødum, Niels, 12 Jun 2014, In : Leukemia. 28, p. 2109-12 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  389. Published

    Annotation of loci from genome-wide association studies using tissue-specific quantitative interaction proteomics

    Lundby, Alicia, Rossin, E. J., Steffensen, Annette Buur, Acha, M. R., Newton-Cheh, C., Pfeufer, A., Lynch, S. N., Olesen, Søren-Peter, Brunak, Søren, Ellinor, P. T., Jukema, J. W., Trompet, S., Ford, I., Macfarlane, P. W., Krijthe, B. P., Hofman, A., Uitterlinden, A. G., Stricker, B. H., Nathoe, H. M., Spiering, W., Daly, M. J., Asselbergs, F. W., van der Harst, P., Milan, D. J., de Bakker, P. I. W., Hansen, K. L., Olsen, Jesper Velgaard & The QT Interval International GWAS Consortium (QT-IGC), T. Q. I. I. G. C. (., 22 Jun 2014, In : Nature Methods. 11, 8, p. 868-874 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  390. Published

    Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization

    Arking, D. E., Pulit, S. L., Crotti, L., van der Harst, P., Munroe, P. B., Koopmann, T. T., Sotoodehnia, N., Rossin, E. J., Morley, M., Wang, X., Johnson, A. D., Lundby, Alicia, Gudbjartsson, D. F., Noseworthy, P. A., Eijgelsheim, M., Bradford, Y., Tarasov, K. V., Dörr, M., Müller-Nurasyid, M., Lahtinen, A. M., Nolte, I. M., Smith, A. V., Bis, J. C., Isaacs, A., Newhouse, S. J., Evans, D. S., Post, W. S., Waggott, D., Lyytikäinen, L., Hicks, A. A., Eisele, L., Ellinghaus, D., Hayward, C., Navarro, P., Ulivi, S., Tanaka, T., Tester, D. J., Chatel, S., Gustafsson, S., Kumari, M., Morris, R. W., Naluai, A. T., Padmanabhan, S., Kluttig, A., Strohmer, B., Panayiotou, A. G., Torres, M., Knoflach, M., Olsen, Jesper Velgaard, Hansen, K. L. & CARe Consortium, C. C., 22 Jun 2014, In : Nature Genetics. 46, 8, p. 826-838 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  391. Published

    PRIME-XS, a European infrastructure for proteomics

    Raijmakers, R., Olsen, Jesper Velgaard, Aebersold, R. & Heck, A. J. R., 23 Jun 2014, In : Molecular & Cellular Proteomics. 13, 8, p. 1901-1904 4 p.

    Research output: Contribution to journalEditorialResearchpeer-review

  392. Published

    Convergence of Ubiquitylation and Phosphorylation Signaling in Rapamycin-Treated Yeast Cells

    Iesmantavicius, V., Weinert, B. T. & Choudhary, Chuna Ram, 24 Jun 2014, In : Molecular & Cellular Proteomics. 13, 8, p. 1979-92 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  393. Published

    Temporal disease trajectories condensed from population-wide registry data covering 6.2 million patients

    Jensen, A. B., Moseley, Pope Lloyd, Oprea, T. I., Ellesøe, S. G., Eriksson, Robert, Schmock, H., Jensen, P. B., Jensen, Lars Juhl & Brunak, Søren, 24 Jun 2014, In : Nature Communications. 5, 10 p., 4022.

    Research output: Contribution to journalJournal articleResearchpeer-review

  394. Published

    XIAP Restricts TNF- and RIP3-Dependent Cell Death and Inflammasome Activation

    Yabal, M., Müller, N., Adler, H., Knies, N., Groß, C. J., Damgaard, R. B., Kanegane, H., Ringelhan, M., Kaufmann, T., Heikenwälder, M., Strasser, A., Groß, O., Ruland, J., Peschel, C., Gyrd-Hansen, M. & Jost, P. J., 26 Jun 2014, In : Cell Reports. 7, 6, p. 1796-1808

    Research output: Contribution to journalJournal articleResearchpeer-review

  395. Published

    Comprehensive Identification of SUMO2/3 Targets and Their Dynamics during Mitosis

    Schou, J., Kelstrup, C. D., Hayward, D. G., Olsen, Jesper Velgaard & Nilsson, Jakob, 27 Jun 2014, In : PLOS ONE. 9, 6, p. e100692 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  396. Published

    Time-resolved dissection of early phosphoproteome and ensuing proteome changes in response to TGF-β

    J D'Souza, R. C., Knittle, A. M., Nagaraj, N., van Dinther, M., Choudhary, Chuna Ram, Ten Dijke, P., Mann, Matthias & Sharma, K., Jul 2014, In : Science signaling. 7, 335, p. rs5 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  397. Published

    The growing landscape of lysine acetylation links metabolism and cell signalling

    Choudhary, Chuna Ram, Weinert, B. T., Nishida, Y., Verdin, E. & Mann, Matthias, 23 Jul 2014, In : Nature Reviews. Molecular Cell Biology. 15, 8, p. 536-50 15 p.

    Research output: Contribution to journalReviewResearchpeer-review

  398. Published

    Revision of the Classical Dopamine D2 Agonist Pharmacophore Based on an Integrated Medicinal Chemistry, Homology Modelling and Computational Docking Approach

    Krogsgaard-Larsen, N., Harpsøe, Kasper, Kehler, J., Christoffersen, C. T., Brøsen, P. & Balle, T., 24 Jul 2014, In : Neurochemical Research. 39, 10, p. 1997-2007 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  399. Published

    Correlation analysis of targeted proteins and metabolites to assess and engineer microbial isopentenol production

    George, K. W., Chen, A., Jain, A., Batth, Tanveer Singh, Baidoo, E. E. K., Wang, G., Adams, P. D., Petzold, C. J., Keasling, J. D. & Lee, T. S., Aug 2014, In : Biotechnology and Bioengineering. 111, 8, p. 1648-58 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  400. Published

    The NBS1-Treacle complex controls ribosomal RNA transcription in response to DNA damage

    Larsen, D. H., Hari, F., Clapperton, J. A., Gwerder, M., Gutsche, K., Altmeyer, M., Jungmichel, S., Toledo Lazaro, Luis Ignacio, Fink, D., Rask, M., Grøfte, M., Lukas, Claudia, Nielsen, Michael Lund, Smerdon, S. J., Lukas, Jiri & Stucki, M., Aug 2014, In : Nature Cell Biology. 16, 8, p. 792-803 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  401. Published

    Lineage-specific interface proteins match up the cell cycle and differentiation in embryo stem cells

    Re, A., Workman, C. T., Waldron, L., Quattrone, A. & Brunak, Søren, 4 Aug 2014, In : Stem Cell Research. 13, 2, p. 316-328 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  402. Published

    Immature truncated O-glycophenotype of cancer directly induces oncogenic features

    Radhakrishnan, P., Dabelsteen, Sally, Madsen, F. B., Francavilla, C., Kopp, K. L., Steentoft, Catharina, Vakhrushev, Sergey, Olsen, Jesper Velgaard, Hansen, Lars, Bennett, Eric Paul, Woetmann, A., Yin, G., Chen, L., Song, H., Bak, Mads, Hlady, R. A., Peters, S. L., Opavsky, R., Thode, C., Qvortrup, Klaus, Schjoldager, Katrine Ter-Borch Gram, Clausen, Henrik, Hollingsworth, M. A. & Wandall, Hans H., 12 Aug 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 39, p. e4066-e4077 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  403. Published

    Analysis of Changes in SUMO-2/3 Modification during Breast Cancer Progression and Metastasis

    Subramonian, D., Raghunayakula, S., Olsen, Jesper Velgaard, Beningo, K. A., Paschen, W. & Zhang, X., Sep 2014, In : Journal of Proteome Research. 13, 9, p. 3905–3918 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  404. Published

    Evolution reveals a glutathione-dependent mechanism of 3-hydroxypropionic acid tolerance

    Kildegaard, K. R., Hallström, B. M., Blicher, T. H., Sonnenschein, N., Jensen, N. B., Sherstyk, S., Harrison, S. J., Maury, J., Herrgård, M. J., Juncker, A. S., Forster, J., Nielsen, J. & Borodina, I., Sep 2014, In : Metabolic Engineering. 26C, p. 57-66 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  405. Published

    Structural insights into the recognition of phosphopeptide by the FHA domain of kanadaptin

    Xu, Q., Deller, M. C., Nielsen, T. K., Grant, J. C., Lesley, S. A., Elsliger, M., Deacon, A. M. & Wilson, I. A., Sep 2014, In : PLOS ONE. 9, 9, 9 p., e107309.

    Research output: Contribution to journalJournal articleResearchpeer-review

  406. Published

    A quantitative 14-3-3 interaction screen connects the nuclear exosome targeting complex to the DNA damage response

    Blasius, M., Wagner, S. A., Choudhary, Chuna Ram, Bartek, J. & Jackson, S. P., 4 Sep 2014, In : Genes & Development. 28, 18, p. 1977-1982 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  407. Published

    Patient stratification and identification of adverse event correlations in the space of 1190 drug related adverse events

    Roitmann, E., Eriksson, Robert & Brunak, Søren, 11 Sep 2014, In : Frontiers in Physiology. 5, 14 p., 332.

    Research output: Contribution to journalJournal articleResearchpeer-review

  408. Published

    Neurophysiological evidence for the presence of cannabinoid CB1 receptors in the laterodorsal tegmental nucleus.

    Soni, N., Satpathy, S. & Kohlmeier, Kristi Anne, 23 Sep 2014, In : European Journal of Neuroscience. 40, 11, p. 3635-3652 18 p.

    Research output: Contribution to journal