The NNF Center for Protein Research

  1. 2020
  2. Published

    Quantitative phosphoproteomics to unravel the cellular response to chemical stressors with different modes of action

    Sampadi, B., Pines, A., Munk, S., Mišovic, B., de Groot, A. J., van de Water, B., Olsen, Jesper Velgaard, Mullenders, L. H. F. & Vrieling, H., 2020, In : Archives of Toxicology. 94, p. 1655-1671 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Rapid and site-specific deep phosphoproteome profiling by data-independent acquisition without the need for spectral libraries

    Bekker-Jensen, D. B., Bernhardt, O. M., Hogrebe, A., Martinez-Val, A., Verbeke, L., Gandhi, T., Kelstrup, C. D., Reiter, L. & Olsen, Jesper Velgaard, 2020, In : Nature Communications. 11, 1

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    SHP1 regulates a STAT6-ITGB3 axis in FLT3ITD-positive AML cells

    Reich, D., Kresinsky, A., Müller, J. P., Bauer, R., Kallenbach, J., Schnoeder, T. M., Heidel, F. H., Fässler, R., Mann, Matthias, Böhmer, F. & Jayavelu, A. K., 2020, In : Leukemia. 34, p. 1444-1449

    Research output: Contribution to journalComment/debateResearch

  5. Published

    Sacubitril/valsartan increases postprandial gastrin and cholecystokinin in plasma

    Andersen, U. O., Terzic, D., Albrechtsen, Nicolai Jacob Wewer, Mark, P. D., Plomgaard, Peter Stendahl, Rehfeld, Jens Frederik, Gustafssons, F. & Goetze, Jens P. , 2020, In : Endocrine Connections. 9, 5, p. 438-444

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Sex differences in text-mined possible adverse drug events associated with drugs for psychosis

    Sørup, F. K. H., Eriksson, Robert, Westergaard, David, Hallas, J., Brunak, Søren & Andersen, Stig Ejdrup, 2020, In : Journal of Psychopharmacology. 34, 5, p. 532-539 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    The biomolecular characterization of a finger ring contextually dated to the emergence of the Early Neolithic from Syltholm, Denmark

    Jensen, Theis Zetner Trolle, Mackie, Meaghan, Taurozzi, Alberto John, Lanigan, Liam Thomas, Gundelach, C., Olsen, J., Sørensen, S. A., Collins, Matthew James, Sørensen, Mikkel & Schroeder, Hannes, 2020, In : Royal Society Open Science. 7, 1, 16 p., 191172.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    The derived allele of a novel intergenic variant at chromosome 11 associates with lower body mass index and a favorable metabolic phenotype in Greenlanders

    Lepola, Mette Andersen, Jørsboe, Emil, Skotte, L., Hanghøj, Kristian Ebbesen, Sandholt, C. H., Moltke, Ida, Grarup, Niels, Kern, T., Mahendran, Y., Søborg, B., Bjerregaard, P., Larsen, C. V. L., Dahl-Petersen, I. K., Tiwari, H. K., Feenstra, B., Koch, A., Wiener, H. W., Hopkins, S. E., Pedersen, Oluf Borbye, Melbye, Mads, Boyer, B. B., Jørgensen, M. E., Albrechtsen, Anders & Hansen, Torben, 2020, In : PLOS Genetics. 16, 1, 17 p., e1008544.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    The role of physical activity in metabolic homeostasis before and after the onset of type 2 diabetes: an IMI DIRECT study

    Koivula, R. W., Atabaki-Pasdar, N., Giordano, G. N., White, T., Adamski, J., Bell, J. D., Beulens, J., Brage, S., Brunak, Søren, De Masi, F., Dermitzakis, E. T., Forgie, I. M., Frost, G., Hansen, Torben, Hansen, Tue Haldor, Hattersley, A., Kokkola, T., Kurbasic, A., Laakso, M., Mari, A., McDonald, T. J., Pedersen, Oluf Borbye, Rutters, F., Schwenk, J. M., Teare, H. J. A., Thomas, E. L., Vinuela, A., Mahajan, A., McCarthy, M. I., Ruetten, H., Walker, M., Pearson, E., Pavo, I., Franks, P. W. & IMI-DIRECT consortium, I. C., 2020, In : Diabetologia. 63, 4, p. 744-756 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Accepted/In press

    Two new polymorphic structures of human full-length alpha-synuclein fibrils solved by cryo-electron microscopy

    Guerrero-Ferreira, R., Taylor, Nicholas M I, Arteni, A., Kumari, P., Mona, D., Ringler, P., Britschgi, M., Lauer, M. E., Makky, A., Verasdonck, J., Riek, R., Melki, R., Meier, B. H., Böckmann, A., Bousset, L. & Stahlberg, H., 2020, (Accepted/In press) In : eLife.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Visualize omics data on networks with Omics Visualizer, a Cytoscape App

    Legeay, Marc, Doncheva, Nadezhda Tsankova, Morris, J. H. & Jensen, Lars Juhl, 2020, In : F1000Research. 9, 1 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Will Artificial Intelligence for Drug Discovery Impact Clinical Pharmacology?

    Zhavoronkov, A., Vanhaelen, Q. & Oprea, T. I., 2020, In : Clinical Pharmacology & Therapeutics. 107, 4, p. 780-785 6 p.

    Research output: Contribution to journalReviewResearchpeer-review

  13. Published

    ZAKα Recognizes Stalled Ribosomes through Partially Redundant Sensor Domains

    Vind, Anna Constance, Snieckute, Goda, Blasius, Melanie, Tiedje, C., Krogh, Nicolai, Bekker-Jensen, D. B., Andersen, Kasper Langebjerg, Nordgaard, Cathrine, Tollenaere, M. A. X., Lund, Anders H., Olsen, Jesper Velgaard, Nielsen, Henrik & Bekker-Jensen, Simon Holst, 2020, In : Molecular Cell. 78, 4, p. 700-713.E7

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. 2019
  15. Published

    High-Throughput Sequencing-Based Investigation of Viruses in Human Cancers by Multienrichment Approach

    Mollerup, S., Asplund, M., Friis-Nielsen, J., Kjartansdóttir, K. R., Fridholm, H., Hansen, T. A., Romero Herrera, Jose Alejandro, Barnes, Christopher James, Jensen, R. H., Richter, S. R., Nielsen, Ida Broman, Pietroni, C., Alquezar-Planas, D. E., Rey de la Iglesia, Alba, Olsen, Pernille Vibeke Selmer, Rajpert-De Meyts, E., Groth-Pedersen, L., von Buchwald, Christian, Jensen, D. H., Gniadecki, R., Høgdall, Estrid Vilma Solyom, Langhoff, J. L., Pete, I., Vereczkey, I., Baranyai, Z., Dybkaer, K., Johnsen, H. E., Steiniche, T., Hokland, P., Rosenberg, Jacob, Baandrup, U., Sicheritz-Pontén, Thomas, Willerslev, Eske, Brunak, Søren, Lund, O., Mourier, T., Vinner, Lasse, Izarzugaza, J. M. G., Nielsen, L. P. & Hansen, Anders Johannes, 15 Oct 2019, In : The Journal of Infectious Diseases. 220, 8, p. 1312-1324

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Herpes Simplex Virus Type 1 infection is associated with suicidal behavior and first registered psychiatric diagnosis in a healthy population

    Nissen, J., Trabjerg, B., Pedersen, M. G., Banasik, Karina, Pedersen, Ole Birger Vesterager, Sørensen, E., Nielsen, K. R., Erikstrup, C., Petersen, M. S., Paarup, H. M., Bruun-Rasmussen, P., Westergaard, David, Hansen, Thomas Folkmann, Pedersen, C. B., Werge, Thomas, Torrey, F., Hjalgrim, H., Mortensen, P. B., Yolken, R., Brunak, Søren, Ullum, Henrik & Burgdorf, K. S., Oct 2019, In : Psychoneuroendocrinology. 108, p. 150-154

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

    Turcot, V., Lu, Y., Highland, H. M., Schurmann, C., Justice, A. E., Fine, R. S., Bradfield, J. P., Esko, T., Giri, A., Graff, M., Guo, X., Hendricks, A. E., Karaderi, T., Lempradl, A., Locke, A. E., Mahajan, A., Marouli, E., Sivapalaratnam, S., Young, K. L., Alfred, T., Feitosa, M. F., Masca, N. G. D., Manning, A. K., Winkler, T. W., Bang, L. E., Benn, Marianne, Bork-Jensen, J., Frikke-Schmidt, Ruth, Grarup, Niels, Hansen, Torben, Have, C. T., Jensen, G. B., Jørgensen, M. E., Jørgensen, T., Kamstrup, P. R., Karpe, F., Kovacs, P., Li, J., Lind, L., Linneberg, Allan René, Nielsen, S. F., Nordestgaard, Børge, Pedersen, Oluf Borbye, Pers, Tune H, Tybjærg-Hansen, Anne, V Varga, Tibor, drb459, drb459, Witte, D. R., Zhao, J. H., Loos, R. J. F. & CHD Exome+ Consortium, C. E. C., Jul 2019, In : Nature Genetics. 51, 7, p. 1191-1192 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    DBDS Genomic Cohort, a prospective and comprehensive resource for integrative and temporal analysis of genetic, environmental and lifestyle factors affecting health of blood donors

    Hansen, Thomas Folkmann, Banasik, Karina, Erikstrup, C., Pedersen, Ole Birger Vesterager, Westergaard, David, Chmura, P. J., Nielsen, K., Thørner, L., Hjalgrim, H., Paarup, H., Larsen, M. A. H., Petersen, M., Jennum, Poul, Andersen, S., Nyegaard, M., Jemec, Gregor, Olesen, Jes, Werge, Thomas, Johansson, P. I., Sørensen, E., Brunak, Søren, Ullum, Henrik & Burgdorf, K. S., 9 Jun 2019, In : BMJ Open. 9, 6, p. 1-7 7 p., e028401.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Functional Differences between Synaptic Mitochondria from the Striatum and the Cerebral Cortex

    Petersen, M. H., Willert, C. W., Andersen, Jens Velde, Waagepetersen, Helle S., Skotte, Niels Henning & Nørremølle, Anne, May 2019, In : Neuroscience. 406, p. 432-443 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    FoxK1 and FoxK2 in insulin regulation of cellular and mitochondrial metabolism

    Sakaguchi, M., Cai, W., Wang, C., Cederquist, C. T., Damasio, M., Homan, E. P., Batista, T., Ramirez, A. K., Gupta, M. K., Steger, M., Albrechtsen, Nicolai Jacob Wewer, Singh, S. K., Araki, E., Mann, M., Enerbäck, S. & Kahn, C. R., 5 Apr 2019, In : Nature Communications. 10, 1, 17 p., 1582.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Molecular dynamics-guided discovery of an ago-allosteric modulator for GPR40/FFAR1

    Lückmann, Michael, Trauelsen, Mette, Bentsen, Marie Aare, Nissen, Tinne Amalie Damgaard, Martins, J., Fallah, Z., Nygaard, Mads Mørup, Papaleo, Elena, Lindorff-Larsen, Kresten, Schwartz, Thue W. & Frimurer, Thomas Michael, 2 Apr 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 14, p. 7123-7128

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Palaeoproteomic analysis of Early Pleistocene Gigantopithecus blacki

    Welker, Frido, Ramos Madrigal, Jazmin, Wang, W., Kuhlwilm, M., Montero, M. D. M., Demeter, Fabrice, Lalueza-Fox, C., Marques-Bonet, T., Olsen, Jesper Velgaard & Cappellini, Enrico, Mar 2019, In : American Journal of Physical Anthropology. 168, suppl. 68, p. 265-266

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  23. Published

    SignalP 5.0 improves signal peptide predictions using deep neural networks

    Armenteros, J. J. A., Tsirigos, Konstantinos, Sønderby, C. K., Petersen, T. N., Winther, Ole, Brunak, Søren, von Heijne, G. & Nielsen, H., 18 Feb 2019, In : Nature Biotechnology. 37, 4, p. 420-423

    Research output: Contribution to journalJournal articleCommunication

  24. Published

    Acetylation of intrinsically disordered regions regulates phase separation

    Saito, M., Hess, D., Eglinger, J., Fritsch, A. W., Kreysing, M., Weinert, B. T., Choudhary, Chuna Ram & Matthias, P., Jan 2019, In : Nature Chemical Biology. 15, 1, p. 51-61

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    53BP1 nuclear bodies enforce replication timing at under-replicated DNA to limit heritable DNA damage

    Spies, Julian, Lukas, Claudia, Somyajit, Kumar, Rask, M., Lukas, Jiri & Neelsen, K. J., 2019, In : Nature Cell Biology. 21, p. 487-497

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published
  27. Published

    A Brief History of Protein Sorting Prediction

    Nielsen, H., Tsirigos, Konstantinos, Brunak, Søren & von Heijne, G., 2019, In : The Protein Journal. 38, 3, p. 200-216 17 p.

    Research output: Contribution to journalReviewResearchpeer-review

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