The NNF Center for Protein Research

  1. 2019
  2. Published

    What outcomes are important to patients with mild cognitive impairment or Alzheimer's disease, their caregivers, and health-care professionals? A systematic review. / ROADMAP consortium.

    In: Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring, Vol. 11, 12.2019, p. 231-247.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Herpes Simplex Virus Type 1 infection is associated with suicidal behavior and first registered psychiatric diagnosis in a healthy population. / Nissen, Janna; Trabjerg, Betina; Pedersen, M G; Banasik, Karina; Pedersen, Ole Birger; Sørensen, Erik; Nielsen, Kaspar René; Erikstrup, Christian; Petersen, Mikkel Steen; Paarup, Helene Martina; Bruun-Rasmussen, Peter; Westergaard, David; Hansen, T F; Pedersen, Carsten B; Werge, Thomas; Torrey, Fuller; Hjalgrim, Henrik; Mortensen, Preben Bo; Yolken, Robert; Brunak, Søren; Ullum, Henrik; Burgdorf, K S.

    In: Psychoneuroendocrinology, Vol. 108, 10.2019, p. 150-154.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Selective autophagy maintains centrosome integrity and accurate mitosis by turnover of centriolar satellites. / Holdgaard, Søs Grønbæk; Cianfanelli, Valentina; Pupo, Emanuela; Lambrughi, Matteo; Lubas, Michal; Nielsen, Julie C; Eibes, Susana; Maiani, Emiliano; Harder, Lea M; Wesch, Nicole; Foged, Mads Møller; Maeda, Kenji; Nazio, Francesca; de la Ballina, Laura R; Dötsch, Volker; Brech, Andreas; Frankel, Lisa B; Jäättelä, Marja; Locatelli, Franco; Barisic, Marin; Andersen, Jens S; Bekker-Jensen, Simon; Lund, Anders H; Rogov, Vladimir V; Papaleo, Elena; Lanzetti, Letizia; De Zio, Daniela; Cecconi, Francesco.

    In: Nature Communications, Vol. 10, No. 1, 13.09.2019, p. 4176.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Early Pleistocene enamel proteome from Dmanisi resolves Stephanorhinus phylogeny. / Cappellini, Enrico; Welker, Frido; Pandolfi, Luca; Ramos-madrigal, Jazmín; Samodova, Diana; Rüther, Patrick L.; Fotakis, Anna K.; Lyon, David; Moreno-mayar, J. Víctor; Bukhsianidze, Maia; Rakownikow Jersie-christensen, Rosa; Mackie, Meaghan; Ginolhac, Aurélien; Ferring, Reid; Tappen, Martha; Palkopoulou, Eleftheria; Dickinson, Marc R.; Stafford, Thomas W.; Chan, Yvonne L.; Götherström, Anders; Nathan, Senthilvel K. S. S.; Heintzman, Peter D.; Kapp, Joshua D.; Kirillova, Irina; Moodley, Yoshan; Agusti, Jordi; Kahlke, Ralf-dietrich; Kiladze, Gocha; Martínez-navarro, Bienvenido; Liu, Shanlin; Sandoval Velasco, Marcela; Sinding, Mikkel-holger S.; Kelstrup, Christian D.; Allentoft, Morten E.; Orlando, Ludovic; Penkman, Kirsty; Shapiro, Beth; Rook, Lorenzo; Dalén, Love; Gilbert, M. Thomas P.; Olsen, Jesper V.; Lordkipanidze, David; Willerslev, Eske.

    In: Nature, 11.09.2019.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. E-pub ahead of print

    Paracrine Crosstalk between Intestinal L- and D-cells Controls Secretion of Glucagon-Like Peptide-1 in mice. / Jepsen, Sara L; Grunddal, Kaare V; Wewer Albrechtsen, Nicolai J; Engelstoft, Maja S; Gabe, Maria B N; Jensen, Elisa P; Ørskov, Cathrine; Poulsen, Steen S; Rosenkilde, Mette M; Pedersen, Jens; Gribble, Fiona M; Reimann, Frank; Deacon, Carolyn F; Schwartz, Thue W; Christ, Andreas D; Martin, Rainer E; Holst, Jens J.

    In: A J P: Endocrinology and Metabolism (Online), 10.09.2019.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Palaeoproteomic identification of breast milk protein residues from the archaeological skeletal remains of a neonatal dog. / Tsutaya, Takumi; Mackie, Meaghan; Koenig, Claire; Sato, Takao; Weber, Andrzej W.; Kato, Hirofumi; Olsen, Jesper V.; Cappellini, Enrico.

    In: Scientific Reports, Vol. 9, No. 1, 12841, 06.09.2019.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Genetic studies of abdominal MRI data identify genes regulating hepcidin as major determinants of liver iron concentration. / IMI-DIRECT consortium.

    In: Journal of Hepatology, Vol. 71, No. 3, 01.09.2019, p. 594-602.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Incorporating symptom data in longitudinal disease trajectories for more detailed patient stratification. / Lademann, Martin; Lademann, Mette; Boeck Jensen, Anders; Brunak, Søren.

    In: International Journal of Medical Informatics, Vol. 129, 09.2019, p. 107-113.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. E-pub ahead of print

    Leveraging European infrastructures to access 1 million human genomes by 2022. / Saunders, Gary; Baudis, Michael; Becker, Regina; Beltran, Sergi; Béroud, Christophe; Birney, Ewan; Brooksbank, Cath; Brunak, Søren; Van den Bulcke, Marc; Drysdale, Rachel; Capella-Gutierrez, Salvador; Flicek, Paul; Florindi, Francesco; Goodhand, Peter; Gut, Ivo; Heringa, Jaap; Holub, Petr; Hooyberghs, Jef; Juty, Nick; Keane, Thomas M; Korbel, Jan O; Lappalainen, Ilkka; Leskosek, Brane; Matthijs, Gert; Mayrhofer, Michaela Th; Metspalu, Andres; Navarro, Arcadi; Newhouse, Steven; Nyrönen, Tommi; Page, Angela; Persson, Bengt; Palotie, Aarno; Parkinson, Helen; Rambla, Jordi; Salgado, David; Steinfelder, Erik; Swertz, Morris A; Valencia, Alfonso; Varma, Susheel; Blomberg, Niklas; Scollen, Serena.

    In: Nature Reviews. Genetics, 27.08.2019.

    Research output: Contribution to journalReviewResearchpeer-review

  11. E-pub ahead of print

    Transcriptome analysis in patients with temporal lobe epilepsy. / Kjær, Christina; Barzaghi, Guido; Bak, Lasse K; Goetze, Jens P; Yde, Christina Westmose; Woldbye, David; Pinborg, Lars H; Jensen, Lars Juhl.

    In: Brain, 26.08.2019.

    Research output: Contribution to journalLetterResearchpeer-review

  12. Published

    Distinct signatures of lung cancer types : aberrant mucin O-glycosylation and compromised immune response. / Lucchetta, Marta; da Piedade, Isabelle; Mounir, Mohamed; Vabistsevits, Marina; Terkelsen, Thilde; Papaleo, Elena.

    In: BMC Cancer, Vol. 19, No. 1, 20.08.2019, p. 824.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. E-pub ahead of print

    A Comparative Assessment Study of Known Small-Molecule Keap1-Nrf2 Protein-Protein Interaction Inhibitors : Chemical Synthesis, Binding Properties, and Cellular Activity. / Tran, Kim Tai; Pallesen, Jakob S; Solbak, Sara Marie Øie; Narayanan, Dilip; Baig, Amina; Zang, Jie; Aguayo-Orozco, Alejandro; Carmona, Rosa; Garcia, Anthony; Bach, Anders.

    In: Journal of Medicinal Chemistry, 14.08.2019.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    The bio.tools registry of software tools and data resources for the life sciences. / Ison, Jon; Ienasescu, Hans; Chmura, Piotr; Rydza, Emil; Ménager, Hervé; Kalaš, Matúš; Schwämmle, Veit; Grüning, Björn; Beard, Niall; Lopez, Rodrigo; Duvaud, Severine; Stockinger, Heinz; Persson, Bengt; Vařeková, Radka Svobodová; Raček, Tomáš; Vondrášek, Jiří; Peterson, Hedi; Salumets, Ahto; Jonassen, Inge; Hooft, Rob; Nyrönen, Tommi; Valencia, Alfonso; Capella, Salvador; Gelpí, Josep; Zambelli, Federico; Savakis, Babis; Leskošek, Brane; Rapacki, Kristoffer; Blanchet, Christophe; Jimenez, Rafael; Oliveira, Arlindo; Vriend, Gert; Collin, Olivier; van Helden, Jacques; Løngreen, Peter; Brunak, Søren.

    In: Genome Biology, Vol. 20, No. 1, 12.08.2019, p. 164.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Structural Basis of BRCC36 Function in DNA Repair and Immune Regulation. / Rabl, Julius; Bunker, Richard D; Schenk, Andreas D; Cavadini, Simone; Gill, Mark E; Abdulrahman, Wassim; Andrés-Pons, Amparo; Luijsterburg, Martijn S; Ibrahim, Adel F M; Branigan, Emma; Aguirre, Jacob D; Marceau, Aimee H; Guérillon, Claire; Bouwmeester, Tewis; Hassiepen, Ulrich; Peters, Antoine H F M; Renatus, Martin; Gelman, Laurent; Rubin, Seth M; Mailand, Niels; van Attikum, Haico; Hay, Ronald T; Thomä, Nicolas H.

    In: Molecular Cell, Vol. 75, No. 3, 08.08.2019, p. 483-497.e9.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    ProtFus : A Comprehensive Method Characterizing Protein-Protein Interactions of Fusion Proteins. / Tagore, Somnath; Gorohovski, Alessandro; Jensen, Lars Juhl; Frenkel-Morgenstern, Milana.

    In: PLOS Computational Biology, Vol. 15, No. 8, 08.2019, p. e1007239.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. E-pub ahead of print

    sAOP : Linking chemical stressors to Adverse Outcomes Pathway Networks. / Aguayo-Orozco, Alejandro; Audouze, Karine; Siggaard, Troels; Barouki, Robert; Brunak, Søren; Taboureau, Olivier.

    In: Bioinformatics (Online), 22.07.2019.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. E-pub ahead of print

    Analysis and Interpretation of Protein Post-Translational Modification Site Stoichiometry. / Prus, Gabriela; Hoegl, Annabelle; Weinert, Brian T; Choudhary, Chunaram.

    In: Trends in Biochemical Sciences, 08.07.2019.

    Research output: Contribution to journalReviewResearchpeer-review

  19. Published

    Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology. / Spracklen, Cassandra N.; Karaderi, Tugce; Yaghootkar, Hanieh; Schurmann, Claudia; Fine, Rebecca S.; Kutalik, Zoltan; Preuss, Michael H.; Lu, Yingchang; Wittemans, Laura B.L.; Adair, Linda S.; Allison, Matthew; Amin, Najaf; Auer, Paul L.; Bartz, Traci M.; Blüher, Matthias; Boehnke, Michael; Borja, Judith B.; Bork-Jensen, Jette; Broer, Linda; Chasman, Daniel I.; Chen, Yii Der Ida; Chirstofidou, Paraskevi; Demirkan, Ayse; van Duijn, Cornelia M.; Feitosa, Mary F.; Garcia, Melissa E.; Graff, Mariaelisa; Grallert, Harald; Grarup, Niels; Guo, Xiuqing; Haesser, Jeffrey; Hansen, Torben; Harris, Tamara B.; Highland, Heather M.; Hong, Jaeyoung; Ikram, M. Arfan; Ingelsson, Erik; Jackson, Rebecca; Jousilahti, Pekka; Kähönen, Mika; Kizer, Jorge R.; Kovacs, Peter; Kriebel, Jennifer; Laakso, Markku; Lange, Leslie A.; Lehtimäki, Terho; Li, Jin; Lind, Lars; Kilpeläinen, Tuomas O.; Loos, Ruth J.F.

    In: American Journal of Human Genetics, Vol. 105, No. 1, 03.07.2019, p. 15-28.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Discovery of biomarkers for glycaemic deterioration before and after the onset of type 2 diabetes : descriptive characteristics of the epidemiological studies within the IMI DIRECT Consortium. / IMI-DIRECT consortium.

    In: Diabetologia, 15.06.2019.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. E-pub ahead of print
  22. Published

    DBDS Genomic Cohort, a prospective and comprehensive resource for integrative and temporal analysis of genetic, environmental and lifestyle factors affecting health of blood donors. / Hansen, Thomas Folkmann; Banasik, Karina; Erikstrup, Christian; Pedersen, Ole Birger; Westergaard, David; Chmura, Piotr Jaroslaw; Nielsen, Kaspar; Thørner, Lise; Hjalgrim, Henrik; Paarup, Helene; Larsen, Margit Anita Hørup; Petersen, Mikkel; Jennum, Poul; Andersen, Steffen; Nyegaard, Mette; Jemec, Gregor Borut Ernst; Olesen, Jes; Werge, Thomas; Johansson, Pär I; Sørensen, Erik; Brunak, Søren; Ullum, Henrik; Burgdorf, Kristoffer Sølvsten.

    In: BMJ Open, Vol. 9, No. 6, e028401, 09.06.2019, p. 1-7.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Palaeoproteomics resolves sloth relationships. / Presslee, Samantha; Slater, Graham J; Pujos, François; Forasiepi, Analía M; Fischer, Roman; Molloy, Kelly; Mackie, Meaghan; Olsen, Jesper V; Kramarz, Alejandro; Taglioretti, Matías; Scaglia, Fernando; Lezcano, Maximiliano; Lanata, José Luis; Southon, John; Feranec, Robert; Bloch, Jonathan; Hajduk, Adam; Martin, Fabiana M; Salas Gismondi, Rodolfo; Reguero, Marcelo; de Muizon, Christian; Greenwood, Alex; Chait, Brian T; Penkman, Kirsty; Collins, Matthew; MacPhee, Ross D E.

    In: Nature Ecology & Evolution, 06.06.2019, p. 1121.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Prediction of human drug-induced liver injury (DILI) in relation to oral doses and blood concentrations. / Albrecht, Wiebke; Kappenberg, Franziska; Brecklinghaus, Tim; Stoeber, Regina; Marchan, Rosemarie; Zhang, Mian; Ebbert, Kristina; Kirschner, Hendrik; Grinberg, Marianna; Leist, Marcel; Moritz, Wolfgang; Cadenas, Cristina; Ghallab, Ahmed; Reinders, Jörg; Vartak, Nachiket; van Thriel, Christoph; Golka, Klaus; Tolosa, Laia; Castell, José V; Damm, Georg; Seehofer, Daniel; Lampen, Alfonso; Braeuning, Albert; Buhrke, Thorsten; Behr, Anne-Cathrin; Oberemm, Axel; Gu, Xiaolong; Kittana, Naim; van de Water, Bob; Kreiling, Reinhard; Fayyaz, Susann; van Aerts, Leon; Smedsrød, Bård; Ellinger-Ziegelbauer, Heidrun; Steger-Hartmann, Thomas; Gundert-Remy, Ursula; Zeigerer, Anja; Ullrich, Anett; Runge, Dieter; Lee, Serene M L; Schiergens, Tobias S; Kuepfer, Lars; Aguayo-Orozco, Alejandro; Sachinidis, Agapios; Edlund, Karolina; Gardner, Iain; Rahnenführer, Jörg; Hengstler, Jan G.

    In: Archives of Toxicology, Vol. 93, No. 6, 06.2019, p. 1609-1637.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. E-pub ahead of print

    Sacubitril/valsartan augments postprandial plasma concentrations of active GLP-1 when combined with sitagliptin in men. / Wewer Albrechtsen, Nicolai J; Mark, Peter D; Terzic, Dijana; Hansen, Lasse H; Andersen, Ulrik Ø; Hartmann, Bolette; Carr, Richard D; Gustafsson, Finn; Deacon, Carolyn F; Holst, Jens J; Goetze, Jens P; Plomgaard, Peter.

    In: The Journal of clinical endocrinology and metabolism, 10.05.2019.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. E-pub ahead of print

    Contaminating viral sequences in high-throughput sequencing viromics : a linkage study of 700 sequencing libraries. / Asplund, Maria; Kjartansdóttir, Kristín Rós; Mollerup, Sarah; Vinner, Lasse; Fridholm, Helena; Herrera, José A R; Friis-Nielsen, Jens; Hansen, Thomas Arn; Jensen, Randi Holm; Nielsen, Ida Broman; Richter, Stine Raith; Rey-Iglesia, Alba; Matey-Hernandez, Maria Luisa; Alquezar-Planas, David E; Olsen, Pernille V S; Sicheritz-Pontén, Thomas; Willerslev, Eske; Lund, Ole; Brunak, Søren; Mourier, Tobias; Nielsen, Lars Peter; Izarzugaza, Jose M G; Hansen, Anders Johannes.

    In: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 03.05.2019.

    Research output: Contribution to journalJournal articleResearchpeer-review

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