The NNF Center for Protein Research

  1. 2019
  2. Published

    Development, use, application of novel TIMS-Tof system

    Mann, Matthias, 2019, In : Molecular & Cellular Proteomics. 18, 8, p. S20 1 p.

    Research output: Contribution to journalConference abstract in journalResearch

  3. Published

    Direct observation of Thermomyces lanuginosus lipase diffusional states by Single Particle Tracking and their remodeling by mutations and inhibition

    Bohr, Søren Schmidt-Rasmussen, Lund, P. M., Kallenbach, A. S., Pinholt, H., Thomsen, J., Iversen, L., Svendsen, A., Christensen, S. M. & Hatzakis, Nikos, 2019, In : Scientific Reports. 9, 11 p., 16169.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Discovery of biomarkers for glycaemic deterioration before and after the onset of type 2 diabetes: descriptive characteristics of the epidemiological studies within the IMI DIRECT Consortium

    Koivula, R. W., Forgie, I. M., Kurbasic, A., Viñuela, A., Heggie, A., Giordano, G. N., Hansen, Tue Haldor, Hudson, M., Koopman, A. D. M., Rutters, F., Siloaho, M., Allin, Kristine Højgaard, Brage, S., Brorsson, C. A., Dawed, A. Y., De Masi, F., Groves, C. J., Kokkola, T., Mahajan, A., Perry, M. H., Rauh, S. P., Ridderstråle, M., Teare, H. J. A., Thomas, E. L., Tura, A., drb459, drb459, White, T., Adamski, J., Bell, J. D., Beulens, J. W., Brunak, Søren, Dermitzakis, E. T., Froguel, P., Frost, G., Gupta, R., Hansen, Torben, Hattersley, A., Jablonka, B., Kaye, J., Laakso, M., McDonald, T. J., Pedersen, Oluf Borbye, Schwenk, J. M., Pavo, I., Mari, A., McCarthy, M. I., Ruetten, H., Walker, M., Pearson, E., Franks, P. W. & IMI-DIRECT consortium, I. C., 2019, In : Diabetologia. 62, 9, p. 1601-1615

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Disruption of Ca2+i Homeostasis and Connexin 43 Hemichannel Function in the Right Ventricle Precedes Overt Arrhythmogenic Cardiomyopathy in Plakophilin-2-Deficient Mice

    Kim, J., Perez-Hernandez, M., Alvarado, F. J., Maurya, S. R., Montnach, J., Yin, Y., Zhang, M., Lin, X., Vasquez, C., Heguy, A., Liang, F., Woo, S., Morley, G. E., Rothenberg, E., Lundby, Alicia, Valdivia, H. H., Cerrone, M. & Delmar, M., 2019, In : Circulation. 140, 12, p. 1015-1030

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Distinct signatures of lung cancer types: aberrant mucin O-glycosylation and compromised immune response

    Lucchetta, M., da Piedade, I., Mounir, M., Vabistsevits, M., Terkelsen, T. & Papaleo, Elena, 2019, In : BMC Cancer. 19, 824.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Dynamic lineage priming is driven via direct enhancer regulation by ERK

    Hamilton, William, Mosesson, Y., Soares Monteiro, Ana Rita, Emdal, Kristina Bennet, Knudsen, Teresa Emmilie Toudal, Francavilla, C., Barkai, N., Olsen, Jesper Velgaard & Brickman, Joshua Mark, 2019, In : Nature. 575, p. 355-360

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Dynamics of the Eukaryotic Replicative Helicase at Lagging-Strand Protein Barriers Support the Steric Exclusion Model

    Kose, H. B., Larsen, Nicolai Balle, Duxin, Julien & Yardimci, H., 2019, In : Cell Reports. 26, 8, p. 2113-2125.e6 19 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Early Pleistocene enamel proteome from Dmanisi resolves Stephanorhinus phylogeny

    Cappellini, Enrico, Welker, Frido, Pandolfi, L., Ramos Madrigal, Jazmin, Samodova, Diana, Rüther, Patrick, Fotaki, Anna Katerina, Lyon, D., Moreno Mayar, José Victor, Bukhsianidze, M., Rakownikow Jersie-Christensen, R., Mackie, Meaghan, Ginolhac, A., Ferring, R., Tappen, M., Palkopoulou, E., Dickinson, M. R., Stafford, T. W., Chan, Y. L., Götherström, A., Nathan, S. K. S. S., Heintzman, P. D., Kapp, J. D., Kirillova, I., Moodley, Y., Agusti, J., Kahlke, R. D., Kiladze, G., Martínez-Navarro, B., Liu, S., Sandoval-Velasco, Marcela, Sinding, Mikkel Holger Strander, Kelstrup, C. D., Allentoft, Morten Erik, Orlando, L., Penkman, K., Shapiro, B., Rook, L., Dalén, L., Gilbert, M Thomas P, Olsen, Jesper Velgaard, Lordkipanidze, D. & Willerslev, Eske, 2019, In : Nature. 574, 7776, p. 103-107 5 p.

    Research output: Contribution to journalLetterResearchpeer-review

  10. Published

    Efficient mitotic checkpoint signaling depends on integrated activities of Bub1 and the RZZ complex

    Zhang, G., Kruse, Thomas, Guasch Boldú, C., Garvanska, Dimitriya Hristoforova, Coscia, Fabian, Mann, Matthias, Barisic, Marin & Nilsson, Jakob, 2019, In : E M B O Journal. 38, 7, e100977.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Elucidating the Function and Cell-Specific Interactions of P2X7 Receptor Variants Linked to Mental Disorders

    Poulsen, Mette Homann, Fang, J. & Pless, Stephan, 2019, p. 109A-110A.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  12. Published

    Enamel proteome sequences from Dmanisi (Georgia) enable molecular phylogeny beyond the limits of ancient DNA preservation

    Cappellini, Enrico, Welker, Frido, Olsen, Jesper Velgaard, Lordkipanidze, D. & Willerslev, Eske, 2019, In : American Journal of Physical Anthropology. 168, suppl. 68, p. 35 1 p.

    Research output: Contribution to journalConference abstract in journalResearch

  13. Published

    Enamel proteome shows that Gigantopithecus was an early diverging pongine

    Welker, Frido, Ramos Madrigal, Jazmin, Kuhlwilm, M., Liao, W., Gutenbrunner, P., de Manuel, M., Samodova, Diana, Mackie, Meaghan, Allentoft, Morten Erik, Bacon, A., Collins, Matthew James, Cox, J., Lalueza-Fox, C., Olsen, Jesper Velgaard, Demeter, Fabrice, Wang, W., Marques-Bonet, T. & Cappellini, Enrico, 2019, In : Nature. 576, p. 262-265

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Enhanced cerebral branched-chain amino acid metabolism in R6/2 mouse model of Huntington's disease

    Andersen, Jens Velde, Skotte, Niels Henning, Aldana Garcia, Blanca Irene, Nørremølle, Anne & Waagepetersen, Helle S., 2019, In : Cellular and Molecular Life Sciences. 76, 12, p. 2449-2461

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Estimating heritability and genetic correlations from large health datasets in the absence of genetic data

    Jia, G., Li, Y., Zhang, H., Chattopadhyay, I., Jensen, A. B., Blair, D. R., Davis, L., Robinson, P. N., Dahlen, T., Brunak, Søren, Benson, M., Edgren, G., Cox, N. J., Gao, X. & Rzhetsky, A., 2019, In : Nature Communications. 10, 11 p., 5508.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology

    Spracklen, C. N., Karaderi, Tugce, Yaghootkar, H., Schurmann, C., Fine, R. S., Kutalik, Z., Preuss, M. H., Lu, Y., Wittemans, L. B. L., Adair, L. S., Allison, M., Amin, N., Auer, P. L., Bartz, T. M., Blüher, M., Boehnke, M., Borja, J. B., Bork-Jensen, J., Broer, L., Chasman, D. I., Chen, Y. D. I., Chirstofidou, P., Demirkan, A., van Duijn, C. M., Feitosa, M. F., Garcia, M. E., Graff, M., Grallert, H., Grarup, Niels, Guo, X., Haesser, J., Hansen, Torben, Harris, T. B., Highland, H. M., Hong, J., Ikram, M. A., Ingelsson, E., Jackson, R., Jousilahti, P., Kähönen, M., Kizer, J. R., Kovacs, P., Kriebel, J., Laakso, M., Lange, L. A., Lehtimäki, T., Li, J., Lind, L., Oskari Kilpeläinen, Tuomas, Loos, R. J. F. & Mohlke, K. L., 2019, In : American Journal of Human Genetics. 105, 1, p. 15-28 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Expression and secretion of a lytic polysaccharide monooxygenase by a fast-growing cyanobacterium

    Russo, D. A., Zedler, J. A. Z., Wittmann, D. N., Möllers Blossom, Benedikt, Singh, Raushan Kumar, Batth, Tanveer Singh, van Oort, B., Olsen, Jesper Velgaard, Bjerrum, Morten Jannik & Jensen, Poul Erik, 2019, In : Biotechnology for Biofuels. 12, 1, 13 p., 74.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Functions and mechanisms of non-histone protein acetylation

    Narita, Takeo, Weinert, B. T. & Choudhary, Chuna Ram, 2019, In : Nature Reviews. Molecular Cell Biology. 20, p. 156-174 19 p.

    Research output: Contribution to journalReviewResearchpeer-review

  19. Published

    GIGYF1/2-Driven Cooperation between ZNF598 and TTP in Posttranscriptional Regulation of Inflammatory Signaling

    Tollenaere, M. A. X., Tiedje, C., Rasmussen, S., Nielsen, J. C., Vind, Anna Constance, Blasius, Melanie, Batth, Tanveer Singh, Mailand, Niels, Olsen, Jesper Velgaard, Gaestel, M. & Bekker-Jensen, Simon Holst, 2019, In : Cell Reports. 26, 13, p. 3511-3521.e4 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Genetic studies of abdominal MRI data identify genes regulating hepcidin as major determinants of liver iron concentration

    Wilman, H. R., Parisinos, C. A., Atabaki-Pasdar, N., Kelly, M., Thomas, E. L., Neubauer, S., Jennison, C., Ehrhardt, B., Baum, P., Schoelsch, C., Freijer, J., Grempler, R., Graefe-Mody, U., Hennige, A., Dings, C., Lehr, T., Scherer, N., Sihinecich, I., Pattou, F., Raverdi, V., Caiazzo, R., Torres, F., Verkindt, H., Mari, A., Tura, A., Giorgino, T., Bizzotto, Froguel, P., Brorsson, Caroline Anna, Brunak, Søren, De Masi, F., Pedersen, H., Banasik, Karina, Thomas, C., Lundgaard, Agnete Troen, Nielsen, A., Mazzoni, Gianluca, Karaderi, Tugce, Rasmussen, Simon, Johansen, Joachim, Allesøe, Rosa Lundbye, Arumugam, Mani, Allin, Kristine Højgaard, Hansen, Torben, Hansen, Tue Haldor, Jonsson, Anna Elisabet, Pedersen, Oluf Borbye, Dutta, Avirup, Vogt, J., drb459, drb459 & IMI-DIRECT consortium, I. C., 2019, In : Journal of Hepatology. 71, 3, p. 594-602 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Genomic Characterization of Cyanophage vB_AphaS-CL131Infecting Filamentous Diazotrophic Cyanobacterium Aphanizomenon flos-aquae Reveals Novel Insights into Virus-Bacterium Interactions

    Šulčius, S., Šimoliūnas, E., Alzbutas, G., Gasiūnas, G., Jauniškis, V., Kuznecova, J., Miettinen, S., Nilsson, E., Meškys, R., Roine, E., Paškauskas, R. & Holmfeldt, K., 2019, In : Applied and Environmental Microbiology. 85, 1, 19 p., e01311-18.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Glucagon Receptor Signaling and Glucagon Resistance

    Janah, L., Kjeldsen, Sasha Alexandra Sampson, Galsgaard, Katrine Douglas, Winther-Sørensen, Marie, Stojanovska, E., Pedersen, J., Knop, Filip Krag, Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2019, In : International Journal of Molecular Sciences. 20, 13, 27 p., 3314.

    Research output: Contribution to journalReviewResearchpeer-review

  23. Published

    Glucagon Receptor Signaling and Lipid Metabolism

    Galsgaard, Katrine Douglas, Pedersen, J., Knop, Filip Krag, Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2019, In : Frontiers in Physiology. 10, 11 p., 413.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Glucose and Amino Acid Metabolism in Mice Depend Mutually on Glucagon and Insulin Receptor Signaling

    Galsgaard, Katrine Douglas, Winther-Sørensen, Marie, Pedersen, J., Kjeldsen, Sasha Alexandra Sampson, Rosenkilde, Mette, Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, 2019, In : American Journal of Physiology: Endocrinology and Metabolism. 316, 4, p. E660-E673

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    HDX-Viewer: interactive 3D visualization of hydrogen-deuterium exchange data

    Bouyssie, D., Lesne, J., Locard-Paulet, Marie, Albigot, R., Burlet-Schiltz, O. & Marcoux, J., 2019, In : Bioinformatics. 35, 24, p. 5331-5333 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Half-Life Extending Modifications of Peptide YY3-36 Direct Receptor-Mediated Internalization

    Bech, E. M., Kaiser, A., Bellmann-Sickert, K., Bohr, Søren Schmidt-Rasmussen, Sørensen, K. K., Elster, L., Hatzakis, Nikos, Pedersen, S. L., Beck-Sickinger, A. G. & Jensen, Knud Jørgen, 2019, In : Molecular Pharmaceutics. 16, 8, p. 3665-3677

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Heavy metal exposure causes changes in the metabolic health-associated gut microbiome and metabolites

    Li, X., Brejnrod, A. D., Ernst, M., Rykær, M., Herschend, J., Olsen, N. M. C., Dorrestein, P. C., Rensing, C. & Sørensen, Søren Johannes, 2019, In : Environment International. 126, p. 454-467 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Hepatic Rab24 controls blood glucose homeostasis via improving mitochondrial plasticity

    Seitz, S., Kwon, Y., Hartleben, G., Juelg, J., Sekar, R., Krahmer, N., Najafi, B., Loft, A., Gancheva, S., Stemmer, K., Feuchtinger, A., de Angelis, M. H., Mueller, T. D., Mann, Matthias, Blueher, M., Roden, M., Diaz, M. B., Behrends, C., Gilleron, J., Herzig, S. & Zeigerer, A., 2019, In : Nature Metabolism. 1, p. 1009-1026

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Heterogeneity in the perirenal region of humans suggests presence of dormant brown adipose tissue that contains brown fat precursor cells

    Jespersen, N. Z., Feizi, A., Andersen, E. S., Heywood, S., Hattel, H. B., Daugaard, S., Peijs, Lone, Bagi, P., Feldt-Rasmussen, Bo, Schultz, H. S., Hansen, N. S., Krogh-Madsen, Rikke, Pedersen, Bente Klarlund, Petrovic, N., Nielsen, S. & Schéele, Camilla Charlotte, 2019, In : Molecular Metabolism. 24, p. 30-43 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    High-Resolution Structure of Cas13b and Biochemical Characterization of RNA Targeting and Cleavage

    Slaymaker, I. M., Mesa, Pablo, Kellner, M. J., Kannan, S., Brignole, E., Koob, J., Feliciano, P. R., Stella, Stefano, Abudayyeh, O. O., Gootenberg, J. S., Strecker, J., Montoya, Guillermo & Zhang, F., 2019, In : Cell Reports. 26, 13, p. 3741-3751.e5 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Identification of Disease-miRNA Networks Across Different Cancer Types Using SWIM

    Fiscon, G., Conte, F., Farina, L., Pellegrini, M., Russo, Francesco & Paci, P., 2019, MicroRNA Target Identification: Methods and Protocols. Laganà, A. (ed.). Humana Press, p. 169-181 13 p. (Methods in Molecular Biology, Vol. 1970).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  32. Published

    Identification of hyper-rewired genomic stress non-oncogene addiction genes across 15 cancer types

    Hjaltelin, Jessica Xin, Izarzugaza, J. M. G., Jensen, Lars Juhl, Russo, Francesco, Westergaard, David & Brunak, Søren, 2019, In : npj Systems Biology and Applications. 5, 10 p., 27.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Identifying Sepsis Phenotypes

    Moseley, Pope Lloyd & Brunak, Søren, 2019, In : J A M A: The Journal of the American Medical Association. 322, 14, p. 1416-1417 2 p.

    Research output: Contribution to journalComment/debateResearch

  34. Published

    Immunity and mental illness: findings from a Danish population-based immunogenetic study of seven psychiatric and neurodevelopmental disorders

    Nudel, R., Benros, M. E., Krebs, M. D., Allesøe, R. L., Lemvigh, C. K., Bybjerg-Grauholm, J., Børglum, A. D., Daly, M. J., Nordentoft, Merete, Mors, O., Hougaard, D. M., Mortensen, P. B., Buil, A., Werge, Thomas, Rasmussen, Simon & Thompson, W. K., 2019, In : European Journal of Human Genetics. 27, p. 1445-1455

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Improving Peptide-Spectrum Matching by Fragmentation Prediction Using Hidden Markov Models

    Kirik, U., Refsgaard, J. C. & Jensen, Lars Juhl, 2019, In : Journal of Proteome Research. 18, 6, p. 2385-2396

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Incorporating symptom data in longitudinal disease trajectories for more detailed patient stratification

    Lademann, M., zmw894, zmw894, Boeck Jensen, A. & Brunak, Søren, 2019, In : International Journal of Medical Informatics. 129, p. 107-113 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Inferring disease-associated long non-coding RNAs using genome - wide tissue expression profiles

    Pan, X., Jensen, Lars Juhl & Gorodkin, Jan, 2019, In : Bioinformatics. 35, 9, p. 1494-1502 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Insights into mitotic checkpoint by integrating CRISPR and RNAi

    Zhang, G., 2019, In : Molecular & Cellular Oncology. 6, 4, 1603436.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Interaction of Sox2 with RNA binding proteins in mouse embryonic stem cells

    Samudyata, Amaral, P. P., Engström, P. G., Robson, S. C., Nielsen, Michael Lund, Kouzarides, T. & Castelo-Branco, G., 2019, In : Experimental Cell Research. 381, 1, p. 129-138 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    International Ring Trial of a High Resolution Targeted Metabolomics and Lipidomics Platform for Serum and Plasma Analysis

    Thompson, J. W., Adams, K. J., Adamski, J., Asad, Y., Borts, D., Bowden, J. A., Byram, G., Dang, V., Dunn, W. B., Fernandez, F., Fiehn, O., Gaul, D. A., Huhmer, A. F. R., Kalli, A., Koal, T., Koeniger, S., Mandal, R., Meier, F., Naser, F. J., O'Neil, D., Pal, A., Patti, G. J., Hai Pham-Tuan, Prehn, C., Raynaud, F. I., Shen, T., Southam, A. D., St John-Williams, L., Sulek, Karolina, Vasilopoulou, C. G., Viant, M., Winder, C. L., Wishart, D., Zhang, L., Zheng, J. & Moseley, M. A., 2019, In : Analytical Chemistry. 91, 22, p. 14407-14416

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Investigating Intestinal Glucagon after Roux-en-Y Gastric Bypass Surgery

    Jorsal, T., Albrechtsen, Nicolai Jacob Wewer, Christensen, M. M., Mortensen, B., Wandall, E., Langholz, E., Friis, S., Worm, D., Ørskov, Cathrine, Støving, R. K., Andries, A., Juhl, C. B., Sørensen, F., Forman, Julie Lyng, Falkenhahn, M., Musholt, P. B., Theis, S., Larsen, P. J., Holst, Jens Juul, Vrang, N., Jelsing, J., Vilsbøll, Tina & Knop, Filip Krag, 2019, In : Journal of Clinical Endocrinology and Metabolism. 104, 12, p. 6403–6416 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Large expert-curated database for benchmarking document similarity detection in biomedical literature search

    Brown, P., Tan, A., El-Esawi, M. A., Liehr, T., Blanck, O., Gladue, D. P., Almeida, G. M. F., Cernava, T., Sorzano, C. O., Yeung, A. W. K., Engel, M. S., Chandrasekaran, A. R., Muth, T., Staege, M. S., Daulatabad, S. V., Widera, D., Zhang, J., Meule, A., Honjo, K., Pourret, O., Yin, C., Zhang, Z., Cascella, M., Flegel, W. A., Goodyear, C. S., van Raaij, M. J., Bukowy-Bieryllo, Z., Campana, L. G., Kurniawan, N. A., Lalaouna, D., Huttner, F. J., Ammerman, B. A., Ehret, F., Cobine, P. A., Tan, E., Han, H., Xia, W., McCrum, C., Dings, R. P. M., Marinello, F., Nilsson, H., Nixon, B., Voskarides, K., Yang, L., Costa, V. D., Bengtsson-Palme, J., Bradshaw, W., Grimm, D. G., Kumar, N., Martis, E., Prieto, D., Sabnis, S. C., Amer, S. E. D. R., Liew, A. W. C., Perco, P., Rahimi, F., Riva, G., Zhang, C., Devkota, H. P., Ogami, K., Basharat, Z., Fierz, W., Siebers, R., Tan, K., Boehme, K. A., Brenneisen, P., Brown, J. A. L., Dalrymple, B. P., Harvey, D. J., Ng, G., Werten, S., Bleackley, M., Dai, Z., Dhariwal, R., Gelfer, Y., Hartmann, M. D., Miotla, P., Tamaian, R., Govender, P., Gurney-Champion, O. J., Kauppila, J. H., Zhang, X., Echeverria, N., Subhash, S., Sallmon, H., Tofani, M., Bae, T., Bosch, O., Cuiv, P. O., Danchin, A., Diouf, B., Eerola, T., Evangelou, E., Filipp, F. V., Klump, H., Kurgan, L., Smith, S. S., Terrier, O., Tuttle, N., Ascher, D. B., Janga, S. C., Schulte, L. N., Becker, D., Browngardt, C., Bush, S. J., Gaullier, G., Ide, K., Meseko, C., Werner, G. D. A., Zaucha, J., Al-Farha, A. A., Greenwald, N. F., Popoola, S. I., Rahman, M. S., Xu, J., Yang, S. Y., Hiroi, N., Alper, O. M., Baker, C. I., Bitzer, M., Chacko, G., Debrabant, B., Dixon, R., Forano, E., Gilliham, M., Kelly, S., Klempnauer, K., Lidbury, B. A., Lin, M. Z., Lynch, I., Ma, W., Maibach, E. W., Mather, D. E., Nandakumar, K. S., Ohgami, R. S., Parchi, P., Tressoldi, P., Xue, Y., Armitage, C., Barraud, P., Chatzitheochari, S., Coelho, L. P., Diao, J., Doxey, A. C., Gobet, A., Hu, P., Kaiser, S., Mitchell, K. M., Salama, M. F., Shabalin, I. G., Song, H., Stevanovic, D., Yadollahpour, A., Zeng, E., Zinke, K., Alimba, C. G., Beyene, T. J., Cao, Z., Chan, S. S., Gatchell, M., Kleppe, A., Piotrowski, M., Torga, G., Woldesemayat, A. A., Cosacak, M. I., Haston, S., Ross, S. A., Williams, R., Wong, A., Abramowitz, M. K., Effiong, A., Lee, S., Abid, M. B., Agarabi, C., Alaux, C., Albrecht, D. R., Atkins, G. J., Beck, C. R., Bonvin, A. M. J. J., Bourke, E., Brand, T., Braun, R. J., Bull, J. A., Cardoso, P., Carter, D., Delahay, R. M., Ducommun, B., Duijf, P. H. G., Epp, T., Eskelinen, E., Fallah, M., Farber, D. B., Fernandez-Triana, J., Feyerabend, F., Florio, T., Friebe, M., Furuta, S., Gabrielsen, M., Gruber, J., Grybos, M., Han, Q., Heinrich, M., Helantera, H., Huber, M., Jeltsch, A., Jiang, F., Josse, C., Jurman, G., Kamiya, H., de Keersmaecker, K., Kristiansson, E., de Leeuw, F., Li, J., Liang, S., Lopez-Escamez, J. 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M., Xiao, S., Xiong, P., Xu, S., Xu, S., Yao, R., Yao, W., Yin, Q., Yu, Y., Zaitsu, M., Zeineb, Z., Zhan, X., Zhang, J., Zhang, R., Zhang, W., Zhang, X., Zheng, S., Zhou, B., Zhou, X., Ahmad, H., Akinwumi, S. A., Albery, G. F., Alhowimel, A., Ali, J., Alshehri, M., Alsuhaibani, M., Anikin, A., Azubuike, S. O., Bach-Mortensen, A., Baltiansky, L., Bartas, M., Belachew, K. Y., Bhardwaj, V., Binder, K., Bland, N. S., Boah, M., Bullen, B., Calabro, G. E., Callahan, T. J., Cao, B., Chalmers, K., Chang, W., Che, Z., Chen, A. T. Y., Chen, H., Chen, H., Chen, Y., Chen, Z., Choi, Y., Chowdhury, M. A. K., Christensen, M. R., Cooke, R. S. C., Cottini, M., Covington, N. V., Cunningham, C., Delarocque, J., Devos, L., Dhar, A. R., Ding, K., Dong, K., Dong, Z., Dreyer, N., Ekstrand, C., Fardet, T., Feleke, B. E., Feurer, T., Freitas, A., Gao, T., Asefa, N. G., Giganti, F., Grabowski, P., Guerra-Mora, J. R., Guo, C., Guo, X., Gupta, H., He, S., Heijne, M., Heinemann, S., Hogrebe, A., Huang, Z., Iskander-Rizk, S., Iyer, L. M., Jahan, Y., James, A. S., Joel, E., Joffroy, B., Jegousse, C., Kambondo, G., Karnati, P., Kaya, C., Ke, A., Kelly, D., Kickert, R., Kidibule, P. E., Kieselmann, J. P., Kim, H. J., Kitazawa, T., Lamberts, A., Li, Y., Liang, H., Linn, S. N., Litfin, T., Liusuo, W., Lygirou, V., Mahato, A. K., Mai, Z., Major, R. W., Mali, S., Mallis, P., Mao, W., Mao, W., Marvin-Dowle, K., Marvin-Dowle, K., Mason, L. D., Merideth, B., Merino-Plaza, M. J., Merlaen, B., Messina, R., Mishra, A. K., Muhammad, J., Musinguzi, C., Nanou, A., Naqash, A., Nguyen, J. T., Nguyen, T. T. H., Ni, D., Nida, Notcovich, S., Ohst, B., Ollivier, Q. R., Osses, D. F., Peng, X., Plantinga, A., Pulia, M., Rafiq, M., Raman, A., Raucher-Chene, D., Rawski, R., Ray, A., Razak, L. A., Rudolf, K., Rusch, P., Sadoine, M. L., Schmidt, A., Schurr, R., Searles, S., Sharma, S., Sheehan, B., Shi, C., Shohayeb, B., Sommerlad, A., Strehlow, J., Sun, X., Sundar, R., Taherzadeh, G., Tahir, N. D. M., Tang, J., Testa, J., Tian, Z., Tingting, Q., Verheijen, G. P., Vickstrom, C., Wang, T., Wang, X., Wang, Z., Wei, P., Wilson, A., Wyart, Yassine, A., Yousefzadeh, A., Zare, A., Zeng, Z., Zhang, C., Zhang, H., Zhang, L., Zhang, T., Zhang, W., Zhang, Z., Zhou, J., Zhu, D., Adamo, V., Adeyemo, A. A., Aggelidou, M., Al-Owaifeer, A. M., Al-Riyami, A. Z., Alzghari, S. K., Andersen, V., Angus, K., Asaduzzaman, M., Asady, H., Ato, D., Bai, X., Baines, R. L., Ballantyne, M., Ban, B., Beck, J., Ben-Nafa, W., Black, E., Blancher, A., Blankstein, R., Bodagh, N., Borges, P. A. V., Brooks, A., Brox-Ponce, J., Brunetti, A., Canham, C. D., Carninci, P., Carvajal, R., Chang, S. C., Chao, J., Chatterjee, P., Chen, H., Chen, Y., Chhatriwalla, A. K., Chikowe, I., Chuang, T., Collevatti, R. G., Valera-Cornejo, D. A., Cuenda, A., Dao, M., Dauga, D., Deng, Z., Devkota, K., Doan, L. V., Elewa, Y. H. A., Fan, D., Faruk, M., Feifei, S., Ferguson, T. S., Fleres, F., Foster, E. J., Foster, C. S., Furer, T., Gao, Y., Garcia-Rivera, E. J., Gazdar, A., George, R. B., Ghosh, S., Gianchecchi, E., Gleason, J. M., Hackshaw, A., Hall, A., Hall, R., Harper, P., Hogg, W. E., Huang, G., Hunter, K. E., IJzerman, A. P., Jesus, C., Jian, G., Lewis, J. S. ,. J., Kanj, S. S., Kaur, H., Kelly, S., Kheir, F., Kichatova, V. S., Kiyani, M., Klein, R., Kovesi, T., Kraschnewski, J. L., Kumar, A. P., Labutin, D., Lazo-Langner, A., Leclercq, G., Li, M., Li, Q., Li, T., Li, Y., Liao, W., Liao, Z., Lin, J., Lizer, J., Lobreglio, G., Lowies, C., Lu, C., Majeed, H., Martin, A., Martinez-Sobrido, L., Meresh, E., Middelveen, M., Mohebbi, A., Mota, J., Mozaheb, Z., Muyaya, L., Nandhakumar, A., Ng, S. H. X., Obeidat, M., Oh, D., Owais, M., Pace-Asciak, P., Panwar, A., Park, C., Patterson, C., Penagos-Tabaree, F., Pianosi, P. T., Pinzi, V., Pridans, C., Psaroulaki, A., Pujala, R. K., Pulido-Arjona, L., Qi, P., Rahman, P., Rai, N. K., Rassaf, T., Refardt, J., Ricciardi, W., Riess, O., Rovas, A., Sacks, F. M., Saleh, S., Sampson, C., Schmutz, A., Sepanski, R., Sharma, N., Singh, M., Spearman, P., Subramaniapillai, M., Swali, R., Tan, C. M., Tellechea, J. I., Thomas, L., Tong, X., Veys, R., Vitriol, V., Wang, H., Wang, J., Wang, J., Waugh, J., Webb, S. A., Williams, B. A., Workman, A. D., Xiang, T., Xie, L., Xu, J., Xu, T., Yang, C., Yoon, J. G., Yuan, C. M., Zaritsky, A., Zhang, Y., Zhao, H., Zuckerman, H., Lyu, R., Pullan, W. & Zhou, Y., 2019, In : Database. 2019, 66 p., baz085.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Large-scale study of Toxoplasma and Cytomegalovirus shows an association between infection and serious psychiatric disorders

    Burgdorf, K. S., Trabjerg, B., Giørtz Pedersen, M., Nissen, J., Banasik, Karina, Birger Pedersen, O., Sørensen, E., René Nielsen, K., Hørup Larsen, M., Erikstrup, C., Bruun-Rasmussen, P., Westergaard, David, Wegner Thørner, L., Hjalgrim, H., Martina Paarup, H., Brunak, Søren, Pedersen, C. B., Fuller Torrey, E., Werge, Thomas, Bo Mortensen, P., Yolken, R. & Ullum, Henrik, 2019, In : Brain, Behavior, and Immunity. 79, p. 152-158

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Leveraging European infrastructures to access 1 million human genomes by 2022

    Saunders, G., Baudis, M., Becker, R., Beltran, S., Béroud, C., Birney, E., Brooksbank, C., Brunak, Søren, Van den Bulcke, M., Drysdale, R., Capella-Gutierrez, S., Flicek, P., Florindi, F., Goodhand, P., Gut, I., Heringa, J., Holub, P., Hooyberghs, J., Juty, N., Keane, T. M., Korbel, J. O., Lappalainen, I., Leskosek, B., Matthijs, G., Mayrhofer, M. T., Metspalu, A., Navarro, A., Newhouse, S., Nyrönen, T., Page, A., Persson, B., Palotie, A., Parkinson, H., Rambla, J., Salgado, D., Steinfelder, E., Swertz, M. A., Valencia, A., Varma, S., Blomberg, N. & Scollen, S., 2019, In : Nature Reviews. Genetics. 20, p. 693-701 9 p.

    Research output: Contribution to journalReviewResearchpeer-review

  45. Published

    Linking glycemic dysregulation in diabetes to symptoms, comorbidities, and genetics through EHR data mining

    Kirk, I. K., Simon, C., Banasik, Karina, Holm, Peter Christoffer, Haue, Amalie Dahl, Jensen, P. B., Jensen, Lars Juhl, Leal Rodriguez, Cristina, Pedersen, M. K., Eriksson, Robert, Andersen, H. U., Almdal, Thomas Peter, Bork-Jensen, J., Grarup, Niels, Borch-Johnsen, K., Pedersen, Oluf Borbye, Pociot, Flemming, Hansen, Torben, Bergholdt, R., Rossing, Peter & Brunak, Søren, 2019, In : eLife. 8, 19 p., e44941.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Mass Spectrometry-Based Plasma Proteomics: Considerations from Sample Collection to Achieving Translational Data

    Ignjatovic, V., Geyer, P. E., Palaniappan, K. K., Chaaban, J. E., Omenn, G. S., Baker, M. S., Deutsch, E. W. & Schwenk, J. M., 2019, In : Journal of Proteome Research. 18, 12, p. 4085-4097

    Research output: Contribution to journalReviewResearchpeer-review

  47. Published

    MaxQuant.Live enables global targeting of more than 25,000 peptides

    Wichmann, C., Meier, F., Virreira Winter, S., Brunner, A., Cox, J. & Mann, Matthias, 2019, In : Molecular and Cellular Proteomics. 18, 5, p. 982-994 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Mechanisms preserving insulin action during high dietary fat intake

    Lundsgaard, Anne-Marie, Holm, J. B., Sjøberg, Kim A, Bojsen-Møller, K. N., Myrmel, L. S., Fjære, E., Jensen, Benjamin Anderschou Holbech, Nicolaisen, Trine Sand, Hingst, Janne Rasmuss, Hansen, S. L., Doll, S., Geyer, P. E., Deshmukh, Atul Shahaji, Holst, Jens Juul, Madsen, L., Kristiansen, Karsten, Wojtaszewski, Jørgen F P, Richter, Erik A. & Kiens, Bente, 2019, In : Cell Metabolism. 29, 1, p. 50-63, e1-e4 19 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Mesothelial Cell HIF1α Expression Is Metabolically Downregulated by Metformin to Prevent Oncogenic Tumor-Stromal Crosstalk

    Hart, P. C., Kenny, H. A., Grassl, N., Watters, K. M., Litchfield, L. M., Coscia, Fabian, Blaženović, I., Ploetzky, L., Fiehn, O., Mann, Matthias, Lengyel, E. & Romero, I. L., 2019, In : Cell Reports. 29, 12, p. 4086-4098.e6

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Metallopeptidase Inhibitor 1 (TIMP-1) promotes receptor tyrosine kinase c-Kit signaling in colorectal cancer

    Nordgaard, Cathrine, Doll, S., Matos, A. L. D. S. A., Høeberg, M., Kazi, J. U., Friis, S., Stenvang, Jan, Rönnstrand, L., Mann, Matthias & Moreira, José, 2019, In : Molecular Oncology. 13, 12, p. 2646-2662

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Methods and Guidelines for Measurement of Glucagon in Plasma

    Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2019, In : International Journal of Molecular Sciences (Online). 20, 10 p., 5416.

    Research output: Contribution to journalReviewResearchpeer-review

  52. Published

    Migraine polygenic risk score associates with efficacy of migraine-specific drugs

    Kogelman, L. J. A., Esserlind, A., Christensen, A. F., Awasthi, S., Ripke, S., Ingason, A., Davidsson, O. B., Erikstrup, C., Hjalgrim, H., Ullum, Henrik, Olesen, Jes, Hansen, Thomas Folkmann, Gudbjartsson, D., Gastafsson, O., Stefansson, K., Stefansson, H., Porsteinsdottir, U., Andersen, S., Banasik, Karina, Brunak, Søren, Buil, A., Burgdorf, K., Gregor, J., Jennum, Poul, Nielsen, K. R., Nyegaard, M., Paarup, H. M., Pedersen, O. B., Sørensen, E., Werge, Thomas, Anttila, V., Artto, V., Belin, A. C., de Boer, I., Boomsma, D. I., Borte, S., Chasman, D. I., Cherkas, L., Cormand, B., Cuenca-Leon, E., Davey-Smith, G., Dichgans, M., van Duijn, C., Esko, T., Ferrari, M., Frants, R. R., Freilinger, T., Furlotte, N., Gormley, P., Griffiths, L., Hamalainen, E., Hiekkala, M., Ikram, M. A., Jarvelin, M., Kajanne, R., Kallela, M., Kaprio, J., Kaunisto, M., Kubisch, C., Kurki, M., Kurth, T., Launer, L., Lehtimaki, T., Lessel, D., Ligthart, L., Litterman, N., van den Maagdenberg, A., Macaya, A., Malik, R., Mangino, M., McMahon, G., Muller-Myhsok, B., Neale, B. M., Northover, C., Nyholt, D. R., Palotie, A., Palta, P., Pedersen, L., Pedersen, N., Posthuma, D., Pozo-Rosich, P., Pressman, A., Raitakari, O., Schurks, M., Sintas, C., Steinberg, S., Strachan, D., Terwindt, G., Vila-Pueyo, M., Wessman, M., Winsvold, B. S., Zhao, H. & Zwart, J., 2019, In : Neurology: Genetics. 5, 6, 12 p., e364.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Mobi-DIK (Ion Mobility DIA Analysis Kit): Targeted analysis software for diaPASEF data improves proteome coverage

    Ha, A., Frank, M., Meier, F., Brunner, A., Kaspar-Schoenefeld, S., Koch, S., Lubeck, M., Raether, O., Collins, B. C., Aebersold, R., Mann, Matthias & Rost, H., 2019, In : Molecular & Cellular Proteomics. 18, 8, p. S17 1 p.

    Research output: Contribution to journalConference abstract in journalResearch

  54. Published

    Molecular architecture of the Jumonji C family histone demethylase KDM5B

    Dorosz, J., Kristensen, L. H., Aduri, N. G., Mirza, Osman Asghar, Lousen, R., Bucciarelli, S., Mehta, V., Sellés Baiget, Selene, Solbak, Sara Marie Øie, Bach, Anders, Mesa, Pablo, Hernandez, P. A., Montoya, Guillermo, Nguyen, T. T. T. N., Rand, Kasper Dyrberg, Boesen, T. & Gajhede, Michael, 2019, In : Scientific Reports. 9, 13 p., 4019.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    Myosin binding protein H-like (MYBPHL): a promising biomarker to predict atrial damage

    Lahm, H., Dressen, M., Beck, N., Doppler, S., Deutsch, M., Matsushima, S., Neb, I., Koenig, K. C., Sideris, K., Voss, S., Eschenbach, L., Puluca, N., Deisenhofer, I., Doll, S., Holdenrieder, S., Mann, Matthias, Lange, R. & Krane, M., 2019, In : Scientific Reports. 9, 8 p., 9986.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    Neurodevelopmental deficits in human isogenic fragile x syndrome neurons

    Utami, K., Skotte, N. H., Colaco, A. R. -., Yusof, N. A. B. M., Sim, B., Yeo, X. Y., Bae, H., Garcia-Miralles, M., Radulescu, C., Jung, S., Mann, Matthias & Pouladi, M., 2019, In : Journal of Neurochemistry. 150, p. 103 1 p.

    Research output: Contribution to journalConference abstract in journalResearch

  57. Published

    New functionalities in the TCGAbiolinks package for the study and integration of cancer data from GDC and GTEx

    Mounir, M., Lucchetta, M., Silva, T. C., Olsen, C., Bontempi, G., Chen, X., Noushmehr, H., Colaprico, A. & Papaleo, Elena, 2019, In : PLOS Computational Biology. 15, 3, 18 p., e1006701.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    Nosographic analysis of osmophobia and field testing of diagnostic criteria including osmophobia

    Chalmer, M. A., Hansen, Thomas Folkmann & Olesen, Jes, 2019, In : Cephalalgia. 39, 1, p. 38-43 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    O12.4. EFFECTS OF THE GLUCAGON-LIKE PEPTIDE-1 RECEPTOR AGONIST EXENATIDE ON BONE STATUS IN OBESE, NON-DIABETIC, ANTIPSYCHOTIC-TREATED SCHIZOPHRENIA SPECTRUM PATIENTS

    Eriksson, Robert, Broberg, B. V., Ishoy, P. L., Bak, N., Andersen, U. B., Jørgensen, Niklas Rye, Knop, Filip Krag & Ebdrup, Bjørn, 2019, In : Schizophrenia Bulletin. 45, Suppl. 2, p. S198-S199 1 p.

    Research output: Contribution to journalConference abstract in journalResearch

  60. Published

    On the hunt for the alternate host of Hemileia vastatrix

    Koutouleas, Tina, Jørgensen, Hans Jørgen Lyngs, Jensen, Birgit, Lillesø, Jens-Peter Barnekow, Junge, A. & Ræbild, Anders, 2019, In : Ecology and Evolution. 9, 23, p. 13619-13631 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. Published

    Oncogenic Mutations Rewire Signaling Pathways by Switching Protein Recruitment to Phosphotyrosine Sites

    Lundby, Alicia, Franciosa, Giulia, Emdal, Kristina Bennet, Refsgaard, J. C., Gnosa, Sebastian Peter, Bekker-Jensen, D. B., Secher, A., Maurya, S. R., Paul, I., Mendez, B. L., Kelstrup, C. D., Francavilla, C., Kveiborg, Marie, Montoya, Guillermo, Jensen, Lars Juhl & Olsen, Jesper Velgaard, 2019, In : Cell. 179, 2, p. 543-560

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. Published

    PAD2-Mediated Citrullination Contributes to Efficient Oligodendrocyte Differentiation and Myelination

    Falcão, A. M., Meijer, M., Scaglione, A., Rinwa, P., Agirre, E., Liang, J., Buch-Larsen, Sara Charlotte, Heskol, A., Frawley, R., Klingener, M., Varas-Godoy, M., Raposo, A. A. S. F., Ernfors, P., Castro, D. S., Nielsen, Michael Lund, Casaccia, P. & Castelo-Branco, G., 2019, In : Cell Reports. 27, 4, p. 1090-1102.e10

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. Published

    Palaeoproteomic identification of breast milk protein residues from the archaeological skeletal remains of a neonatal dog

    Tsutaya, T., Mackie, Meaghan, Koenig, C., Sato, T., Weber, A. W., Kato, H., Olsen, Jesper Velgaard & Cappellini, Enrico, 2019, In : Scientific Reports. 9, 7 p., 12841.

    Research output: Contribution to journalJournal articleResearchpeer-review

  64. Published

    Palaeoproteomics resolves sloth relationships

    Presslee, S., Slater, G. J., Pujos, F., Forasiepi, A. M., Fischer, R., Molloy, K., Mackie, Meaghan, Olsen, Jesper Velgaard, Kramarz, A., Taglioretti, M., Scaglia, F., Lezcano, M., Lanata, J. L., Southon, J., Feranec, R., Bloch, J., Hajduk, A., Martin, F. M., Salas Gismondi, R., Reguero, M., de Muizon, C., Greenwood, A., Chait, B. T., Penkman, K., Collins, Matthew James & MacPhee, R. D. E., 2019, In : Nature Ecology & Evolution. 3, p. 1121-1130

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. Published

    Parallel accumulation - serial fragmentation combined with data-independent acquisition (diaPASEF)

    Meier, F., Brunner, A., Frank, M., Ha, A., Voytik, E., Kaspar-Schoenefeld, S., Lubeck, M., Raether, O., Aebersold, R., Collins, B. C., Roest, H. L. & Mann, Matthias, 2019, In : Molecular & Cellular Proteomics. 18, 8, p. S17 1 p.

    Research output: Contribution to journalConference abstract in journalResearch

  66. Published

    Patterns of co-occurrence of congenital heart defects follows distinct patterns

    Ellesøe, S. G., Workman, C. T., Bouvagnet, P., Loffredo, C. A., McBride, K. L., Hinton, R. B., van Engelen, K., Gertsen, E. C., Mulder, B. J. M., Postma, A. V., Anderson, R. H., Hjortdal, Vibeke Elisabeth, Brunak, Søren & Larsen, Lars Allan, 2019, In : European Journal of Human Genetics. 26, p. 106 1 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  67. Published

    Persons who have never had a headache. Socio-demographic characteristics

    Olofsson, I. A., Erikstrup, C., Sørensen, E., Paarup, H. M., Mathiasen, H. P., Hjalmgrim, H., Banasik, Karina, Nielsen, K. R., Burgdorf, K. S., Pedersen, Ole Birger Vesterager, Ullum, Henrik, Olesen, Jes & Hansen, Thomas Folkmann, 2019, In : Cephalalgia. 39, 1, suppl., p. 88-89 1 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  68. Published

    Plasma Proteome Profiling to detect and avoid sample-related biases in biomarker studies

    Geyer, P. E., Voytik, E., Treit, P. V., Doll, S., Kleinhempel, A., Niu, Lili, Müller, J. B., Buchholtz, M., Bader, J. M., Teupser, D., Holdt, L. M. & Mann, Matthias, 2019, In : EMBO Molecular Medicine. 11, 11, e10427.

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. Published

    Plasma proteome profiling discovers novel proteins associated with non-alcoholic fatty liver disease

    Niu, Lili, Geyer, P. E., Albrechtsen, Nicolai Jacob Wewer, Gluud, Lise Lotte, Santos, A., Doll, S., Treit, P. V., Holst, Jens Juul, Knop, Filip Krag, Vilsbøll, Tina, Junker, A., Sachs, S., Stemmer, K., Müller, T. D., Tschöp, M. H., Hofmann, S. M. & Mann, Matthias, 2019, In : Molecular Systems Biology. 15, 16 p., e8793.

    Research output: Contribution to journalJournal articleResearchpeer-review

  70. Published

    Population-wide analysis of differences in disease progression patterns in men and women

    Westergaard, David, Moseley, Pope Lloyd, Sørup, F. K. H., Baldi, P. & Brunak, Søren, 2019, In : Nature Communications. 10, 1, 14 p., 666.

    Research output: Contribution to journalJournal articleResearchpeer-review

  71. Published

    Predicting treatment response using pharmacy register in migraine

    Hansen, Thomas Folkmann, Chalmer, M. A., Haspang, T. M., Kogelman, L. & Olesen, Jes, 2019, In : The Journal of Headache and Pain. 20, p. 31 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  72. Published

    Prediction of human drug-induced liver injury (DILI) in relation to oral doses and blood concentrations

    Albrecht, W., Kappenberg, F., Brecklinghaus, T., Stoeber, R., Marchan, R., Zhang, M., Ebbert, K., Kirschner, H., Grinberg, M., Leist, M., Moritz, W., Cadenas, C., Ghallab, A., Reinders, J., Vartak, N., van Thriel, C., Golka, K., Tolosa, L., Castell, J. V., Damm, G., Seehofer, D., Lampen, A., Braeuning, A., Buhrke, T., Behr, A., Oberemm, A., Gu, X., Kittana, N., van de Water, B., Kreiling, R., Fayyaz, S., van Aerts, L., Smedsrød, B., Ellinger-Ziegelbauer, H., Steger-Hartmann, T., Gundert-Remy, U., Zeigerer, A., Ullrich, A., Runge, D., Lee, S. M. L., Schiergens, T. S., Kuepfer, L., Aguayo Orozco, Alejandro, Sachinidis, A., Edlund, K., Gardner, I., Rahnenführer, J. & Hengstler, J. G., 2019, In : Archives of Toxicology. 93, 6, p. 1609-1637 29 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  73. Published

    Prediction of pancreatic fat and analysis of its determining factors using multi-omics datasets: an IMI DIRECTstudy

    Karaderi, Tugce, Mazzoni, Gianluca, Brorsson, Caroline Anna, Westergaard, David, Banasik, Karina, Koivula, R., Thomas, L., Bell, J., Franks, P., Pearson, E. & Brunak, Søren, 2019, In : Diabetologia. 62, p. S166-S166

    Research output: Contribution to journalConference abstract in journalResearch

  74. Published

    Prevalence of patients with self‐reported hidradenitis suppurativa in a cohort of Danish blood donors: a cross‐sectional study

    Riis, P. T., Pedersen, O. B., Sigsgaard, V., Erikstrup, C., Paarup, H. M., Nielsen, K. R., Burgdorf, K. S., Hjalgrim, H., Rostgaard, K., Banasik, Karina, Ullum, Henrik & Jemec, Gregor, 2019, In : British Journal of Dermatology. 180, 4, p. 774-781

    Research output: Contribution to journalJournal articleResearchpeer-review

  75. Published

    Proceedings of the EuBIC Winter School 2019

    Kopczynski, D., Bittremieux, W., Bouyssié, D., Dorfer, V., Locard-Paulet, Marie, Van Puyvelde, B., Schwämmle, V., Soggiu, A., Willems, S. & Uszkoreit, J., 2019, In : EuPA Open Proteomics. 22-23, p. 4-7 4 p.

    Research output: Contribution to journalConference articleResearchpeer-review

  76. Published

    Promoting transparency and reproducibility in enhanced molecular simulations

    Bonomi, M., Bussi, G., Camilloni, C., Tribello, G. A., Banas, P., Barducci, A., Bernetti, M., Bolhuis, P. G., Bottaro, S., Branduardi, D., Capelli, R., Carloni, P., Ceriotti, M., Cesari, A., Chen, H., Chen, W., Colizzi, F., De, S., De La Pierre, M., Donadio, D., Drobot, V., Ensing, B., Ferguson, A. L., Filizola, M., Fraser, J. S., Fu, H., Gasparotto, P., Gervasio, F. L., Giberti, F., Gil-Ley, A., Giorgino, T., Heller, G. T., Hocky, G. M., Iannuzzi, M., Invernizzi, M., Jelfs, K. E., Jussupow, A., Kirilin, E., Laio, A., Limongelli, V., Lindorff-Larsen, Kresten, Lohr, T., Marinelli, F., Martin-Samos, L., Masetti, M., Meyer, R., Michaelides, A., Molteni, C., Morishita, T., Nava, M., Paissoni, C., Papaleo, Elena, Parrinello, M., Pfaendtner, J., Piaggi, P., Piccini, G., Pietropaolo, A., Pietrucci, F., Pipolo, S., Provasi, D., Quigley, D., Raiteri, P., Raniolo, S., Rydzewski, J., Salvalaglio, M., Sosso, G. C., Spiwok, V., Sponer, J., Swenson, D. W. H., Tiwary, P., Valsson, O., Vendruscolo, M., Voth, G. A. & White, A., 2019, In : Nature Methods. 16, 8, p. 670-673

    Research output: Contribution to journalEditorialResearchpeer-review

  77. Published

    ProtFus: A Comprehensive Method Characterizing Protein-Protein Interactions of Fusion Proteins

    Tagore, S., Gorohovski, A., Jensen, Lars Juhl & Frenkel-Morgenstern, M., 2019, In : PLOS Computational Biology. 15, 8, 16 p., e1007239.

    Research output: Contribution to journalJournal articleResearchpeer-review

  78. Published

    Protein aggregation capture on microparticles enables multi-purpose proteomics sample preparation

    Batth, Tanveer Singh, Tollenaere, M. A. X., Rüther, Patrick, Gonzalez-Franquesa, Alba, Prabhakar, B. S., Bekker-Jensen, Simon Holst, Deshmukh, Atul Shahaji & Olsen, Jesper Velgaard, 2019, In : Molecular and Cellular Proteomics. 18, 5, p. 1027-1035

    Research output: Contribution to journalJournal articleResearchpeer-review

  79. Published

    Protein phosphatases in the regulation of mitosis

    Nilsson, Jakob, 2019, In : The Journal of Cell Biology. 218, 2, 15 p., 395.

    Research output: Contribution to journalReviewResearchpeer-review

  80. Published

    Proteogenomic characterization of patient-derived xenografts highlights the role of REST in neuroendocrine differentiation of castration-resistant prostate cancer

    Flores-Morales, A., Bergmann, Tobias Borgtoft, Lavallee, C., Batth, Tanveer Singh, Lin, D., Lerdrup, Mads, Friis, S., Bartels, A., Kristensen, G., Krzyzanowska, A., Xue, H., Fazli, L., Hansen, Klaus, Røder, Martin Andreas, Brasso, Klaus, Moreira, José, Bjartell, A., Wang, Y., Olsen, Jesper Velgaard, Collins, C. C. & Iglesias Gato, Diego, 2019, In : Clinical Cancer Research. 25, 2, p. 1-15

    Research output: Contribution to journalJournal articleResearchpeer-review

  81. Published

    Proteomic characterization of chromosomal common fragile site (CFS)-associated proteins uncovers ATRX as a regulator of CFS stability

    Pladevall Morera, David, Munk, S., Ingham, Andreas, Garribba, L., Albers, E., Liu, Ying, Olsen, Jesper Velgaard & Lopez-Contreras, Andres, 2019, In : Nucleic Acids Research. 47, 15, p. 8004-8018 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  82. Published

    Proteomics of Cytochrome c Oxidase-Negative versus -Positive Muscle Fiber Sections in Mitochondrial Myopathy

    Murgia, M., Tan, J., Geyer, P. E., Doll, S., Mann, Matthias & Klopstock, T., 2019, In : Cell Reports. 29, 12, p. 3825-3834 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  83. Published

    Proteomics reveals NNMT as a master metabolic regulator of cancer-associated fibroblasts

    Eckert, M. A., Coscia, Fabian, Chryplewicz, A., Chang, J. W., Hernandez, K. M., Pan, S., Tienda, S. M., Nahotko, D. A., Li, G., Blaženović, I., Lastra, R. R., Curtis, M., Yamada, S. D., Perets, R., McGregor, S. M., Andrade, J., Fiehn, O., Moellering, R. E., Mann, Matthias & Lengyel, E., 2019, In : Nature. 569, 7758, p. 723-728

    Research output: Contribution to journalLetterResearchpeer-review

  84. Published

    Proteomics-Based Comparative Mapping of the Secretomes of Human Brown and White Adipocytes Reveals EPDR1 as a Novel Batokine

    Deshmukh, Atul Shahaji, Peijs, Lone, Beaudry, J. L., Jespersen, N. Z., Nielsen, Carsten Haagen, Ma, T., Brunner, A. D., Larsen, T. J., Bayarri-Olmos, R., Prabhakar, B. S., Helgstrand, C., Severinsen, M. C. K., Holst, Birgitte, Kjær, Andreas, Tang-Christensen, M., Sanfridson, A., Garred, Peter, Privé, G. G., Pedersen, Bente Klarlund, Gerhart-Hines, Z., Nielsen, S., Drucker, D. J., Mann, Matthias & Schéele, Camilla Charlotte, 2019, In : Cell Metabolism. 30, 5, p. 963-975.e7 21 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  85. Published

    Quantitative proteomics and single-nucleus transcriptomics of the sinus node elucidates the foundation of cardiac pacemaking

    Linscheid, N., Logantha, S. J. R. J., Poulsen, C., Zhang, S., Schrölkamp, Maren, Egerod, Kristoffer Lihme, Thompson, J. J., Kitmitto, A., Galli, G., Humphries, M. J., Zhang, H., Pers, Tune H, Olsen, Jesper Velgaard, Boyett, M. & Lundby, Alicia, 2019, In : Nature Communications. 10, 19 p., 2889.

    Research output: Contribution to journalJournal articleResearchpeer-review

  86. Published

    Quick and clean: Cracking sentences encoded in E. coli by LC-MS/MS, de novo sequencing, and dictionary search

    Niu, Lili & Mann, Matthias, 2019, In : EuPA Open Proteomics. 22-23, p. 30-35 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  87. Published

    Reevaluation of genetic variants previously associated with arrhythmogenic right ventricular cardiomyopathy integrating population-based cohorts and proteomics data

    Ye, J. Z., Delmar, M., Lundby, Alicia & Olesen, Morten Steen Salling, 2019, In : Clinical Genetics. 96, 6, p. 506-514

    Research output: Contribution to journalJournal articleResearchpeer-review

  88. Published

    Regulation of ETAA1-mediated ATR activation couples DNA replication fidelity and genome stability

    Achuthankutty, D., Thakur, Roshan Singh, Haahr, Peter Thorlund, Hoffmann, Saskia, Drainas, A. P., Bizard, Anna Helene, Weischenfeldt, Joachim Lütken, Hickson, Ian David & Mailand, Niels, 2019, In : The Journal of Cell Biology. 218, 12, 11 p., 3943.

    Research output: Contribution to journalJournal articleResearchpeer-review

  89. Published

    Regulation of GLI1 by cis DNA elements and epigenetic marks

    Taylor, R., Long, J., Yoon, J. W., Childs, R., Sylvestersen, K. B., Nielsen, Michael Lund, Leong, K., Iannaccone, S., Walterhouse, D. O., Robbins, D. J. & Iannaccone, P., 2019, In : DNA Repair. 79, p. 10-21 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  90. Published

    Regulation of the cancer-related Src kinase by S-nitrosylation

    Bignon, E. & Papaleo, Elena, 2019, In : Free Radical Biology and Medicine. 139, p. S13-S14

    Research output: Contribution to journalConference abstract in journalResearch

  91. Published

    Replication-Coupled DNA-Protein Crosslink Repair by SPRTN and the Proteasome in Xenopus Egg Extracts

    Larsen, Nicolai Balle, Gao, A. O., Sparks, J. L., Gallina, Irene, Wu, R. A., Mann, Matthias, Räschle, M., Walter, J. C. & Duxin, Julien, 2019, In : Molecular Cell. 73, 3, p. 574-588.e7 23 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  92. Published

    Response to Raaijmakers & Medema

    Zhang, G., Kruse, Thomas, Boldú, C. G., Garvanska, Dimitriya Hristoforova, Coscia, Fabian, Mann, Matthias, Barisic, Marin & Nilsson, Jakob, 2019, In : The EMBO Journal. 38, 22, 5 p., e103547.

    Research output: Contribution to journalComment/debateResearch

  93. Published

    Roadmap for a precision-medicine initiative in the Nordic region

    Njølstad, P. R., Andreassen, O. A., Brunak, Søren, Børglum, A. D., Dillner, J., Esko, T., Franks, P. W., Freimer, N., Groop, L., Heimer, H., Hougaard, D. M., Hovig, E., Hveem, K., Jalanko, A., Kaprio, J., Knudsen, G. P., Melbye, Mads, Metspalu, A., Mortensen, P. B., Palmgren, J., Palotie, A., Reed, W., Stefánsson, H., Stitziel, N. O., Sullivan, P. F., Thorsteinsdóttir, U., Vaudel, M., Vuorio, E., Werge, Thomas, Stoltenberg, C. & Stefánsson, K., 2019, In : Nature Genetics. 51, p. 924-930

    Research output: Contribution to journalComment/debateResearch

  94. Published

    SILAC-based quantitative mass spectrometry-based proteomics quantifies endoplasmic reticulum stress in whole HeLa cells

    Itzhak, D. N., Sacco, F., Nagaraj, N., Tyanova, S., Mann, Matthias & Murgia, M., 2019, In : Disease Models & Mechanisms. 12, 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  95. Published

    STRING v11: protein-protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets

    Szklarczyk, D., Gable, A. L., Lyon, D., Junge, A., Wyder, S., Huerta-Cepas, J., Simonovic, M., Doncheva, Nadezhda Tsankova, Morris, J. H., Bork, P., Jensen, Lars Juhl & von Mering, C., 2019, In : Nucleic Acids Research. 47, D1, p. D607-D613 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  96. Published

    SUMOylation promotes protective responses to DNA-protein crosslinks

    Borgermann, N., Ackermann, Leena, Schwertman, P., Hendriks, Ivo Alexander, Thijssen, K., Liu, Julio, Lans, H., Nielsen, Michael Lund & Mailand, Niels, 2019, In : E M B O Journal. 38, 17 p., e101496.

    Research output: Contribution to journalJournal articleResearchpeer-review

  97. Published

    Sacubitril/Valsartan Augments Postprandial Plasma Concentrations of Active GLP-1 When Combined With Sitagliptin in Men

    Albrechtsen, Nicolai Jacob Wewer, Mark, P. D., Terzic, D., Hansen, L. H., Andersen, U. Ø., Hartmann, Bolette, Carr, R. D., Gustafsson, Finn, Deacon, Carolyn F., Holst, Jens Juul, Goetze, Jens P. & Plomgaard, Peter Stendahl, 2019, In : Journal of Clinical Endocrinology and Metabolism. 104, 9, p. 3868-3876

    Research output: Contribution to journalJournal articleResearchpeer-review

  98. Published

    Selective autophagy maintains centrosome integrity and accurate mitosis by turnover of centriolar satellites

    Holdgaard, S. G., Cianfanelli, V., Pupo, E., Lambrughi, M., Lubas, M., Nielsen, J. C., Eibes, S., Maiani, E., Harder, L. M., Wesch, N., Foged, M. M., Maeda, K., Nazio, F., de la Ballina, L. R., Dötsch, V., Brech, A., Frankel, Lisa, Jäättelä, M., Locatelli, F., Barisic, Marin, Andersen, J. S., Bekker-Jensen, Simon Holst, Lund, Anders H., Rogov, V. V., Papaleo, Elena, Lanzetti, L., De Zio, D. & Cecconi, F., 2019, In : Nature Communications. 10, 1, p. 1-19 19 p., 4176.

    Research output: Contribution to journalJournal articleResearchpeer-review

  99. Published

    Self-reported restless legs syndrome and involuntary leg movements during sleep are associated with symptoms of attention deficit hyperactivity disorder

    Didriksen, M., Thørner, L. W., Erikstrup, C., Pedersen, O. B., Paarup, H. M., Petersen, M., Hansen, T. F., Banasik, Karina, Nielsen, K. R., Hjalgrim, H., Jennum, Poul, Sørensen, E., Burgdorf, K. S. & Ullum, Henrik, 2019, In : Sleep Medicine. 57, p. 115-121 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  100. Published

    Sleep-wake cycles drive daily dynamics of synaptic phosphorylation

    Brüning, F., Noya, S. B., Bange, T., Koutsouli, S., Rudolph, J. D., Tyagarajan, S. K., Cox, J., Mann, Matthias, Brown, S. A. & Robles, M. S., 2019, In : Science (New York, N.Y.). 366, 6462, eaav3617 .

    Research output: Contribution to journalJournal articleResearchpeer-review

  101. Published

    SnapShot: S-Phase Entry and Exit

    Burgess, A., Vuong, J., Marzec, K. A., de Lichtenberg, U. N., O'Donoghue, S. I. & Jensen, Lars Juhl, 2019, In : Cell. 179, 3, p. 802-802.e1 2 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

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