The NNF Center for Protein Research

  1. Published

    Population genomics of bronze age Eurasia

    Allentoft, Morten Erik, Sikora, Martin, Sjogren, K., Rasmussen, S., Rasmussen, M., Stenderup, J., Damgaard, P. D. B., Schroeder, Hannes, Ahlstrom, T., Vinner, Lasse, Malaspinas, A. S., Margaryan, Ashot, Higham, T., Chivall, D., Lynnerup, Niels, Harvig, L. L., Baron, J., Della Casa, P., Dabrowski, P., Duffy, P. R., Ebel, A. V., Epimakhov, A., Frei, K., Furmanek, M., Gralak, T., Gromov, A., Gronkiewicz, S., Grupe, G., Hajdu, T., Jarysz, R., Khartanovich, V., Khokhlov, A., Kiss, V., Kolar, J., Kriiska, A., Lasak, I., Longhi, C., McGlynn, G., Merkevicius, A., Merkyte, I., Metspalu, M., Mkrtchyan, R., Moiseyev, V., Paja, L., Palfi, G., Pokutta, D., Pospieszny, L., Price, T. D., Saag, L., Sablin, M., Shishlina, N., Smrcka, V., Soenov, V. I., Szeverenyi, V., Toth, G., Trifanova, S. V., Varul, L., Vicze, M., Yepiskoposyan, L., Zhitenev, V., Orlando, Ludovic Antoine Alexandre, Sicheritz-Ponten, T., Brunak, Søren, Nielsen, Rasmus, Kristiansen, K. & Willerslev, Eske, 2015, In : Nature Genetics. 522, 7555, p. 167-172 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Genetic determinants of serum vitamin B12 and their relation to body mass index

    Allin, Kristine Højgaard, Friedrich, N., Pietzner, M., Grarup, Niels, Thuesen, B. H., Linneberg, Allan René, Pisinger, Charlotta Holm, Hansen, Torben, Pedersen, Oluf Borbye & Sandholt, C. H., Feb 2017, In : European Journal of Epidemiology. 32, 2, p. 125–134

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Principal component analysis of proteomics (PCAP) as a tool to direct metabolic engineering

    Alonso-Gutierrez, J., Kim, E., Batth, Tanveer Singh, Cho, N., Hu, Q., Chan, L. J. G., Petzold, C. J., Hillson, N. J., Adams, P. D., Keasling, J. D., Garcia Martin, H. & Lee, T. S., Mar 2015, In : Metabolic Engineering. 28, p. 123-133 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Standardized benchmarking in the quest for orthologs

    Altenhoff, A. M., Boeckmann, B., Capella-Gutierrez, S., Dalquen, D. A., DeLuca, T., Forslund, K., Huerta-Cepas, J., Linard, B., Pereira, C., Pryszcz, L. P., Schreiber, F., da Silva, A. S., Szklarczyk, D., Train, C., Bork, P., Lecompte, O., von Mering, C., Xenarios, I., Sjölander, K., Jensen, Lars Juhl, Martin, M. J., Muffato, M., Gabaldón, T., Lewis, S. E., Thomas, P. D., Sonnhammer, E., Dessimoz, C. & Quest for Orthologs consortium, Q. F. O. C., May 2016, In : Nature Methods. 13, p. 425-30 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Text mining for biology--the way forward: opinions from leading scientists

    Altman, R. B., Bergman, C. M., Blake, J., Blaschke, C., Cohen, A., Gannon, F., Grivell, L., Hahn, U., Hersh, W., Hirschman, L., Jensen, Lars Juhl, Krallinger, M., Mons, B., O'Donoghue, S. I., Peitsch, M. C., Rebholz-Schuhmann, D., Shatkay, H. & Valencia, A., 2008, In : Genome Biology (Online Edition). 9 Suppl 2, p. S7

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    To spread or not to spread - chromatin modifications in response to DNA damage

    Altmeyer, M. & Lukas, Jiri, 9 Jan 2013, In : Current Opinion in Genetics & Development. 23, 2, p. 156-165 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Liquid demixing of intrinsically disordered proteins is seeded by poly(ADP-ribose)

    Altmeyer, M., Neelsen, K. J., Teloni, F., Pozdnyakova, I., Pellegrino, S., Grøfte, M., Rask, M. D., Streicher, W., Jungmichel, S., Nielsen, Michael Lund & Lukas, Jiri, 19 Aug 2015, In : Nature Communications. 6, p. 1-12 8088.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Addicted to PAR? A closer look at PARP inhibitor sensitivity

    Altmeyer, M., 2012, In : Cell Cycle. 11, 21, p. 3916 1 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  9. Published

    Guarding against Collateral Damage during Chromatin Transactions

    Altmeyer, M. & Lukas, Jiri, 20 Jun 2013, In : Cell. 153, 7, p. 1431-4 4 p.

    Research output: Contribution to journalReviewResearchpeer-review

  10. Published

    The Chromatin Scaffold Protein SAFB1 Renders Chromatin Permissive for DNA Damage Signaling

    Altmeyer, M., Toledo Lazaro, Luis Ignacio, Gudjonsson, T., Grøfte, M., Rask, M., Lukas, Claudia, Akimov, V., Blagoev, B., Bartek, J. & Lukas, Jiri, 24 Oct 2013, In : Molecular Cell. 52, 2, p. 206-220

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Electron Microscopy Structural Insights into CPAP Oligomeric Behavior: A Plausible Assembly Process of a Supramolecular Scaffold of the Centrosome

    Alvarez-Cabrera, A. L., Delgado, S., Gil-Carton, D., Mortuza, G. B., Montoya, Guillermo, Sorzano, C. O. S., Tang, T. K. & Carazo, J. M., 2017, In : Frontiers in Molecular Biosciences. 4, 14 p., 17.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Ligand-selective small molecule modulators of the constitutively active vGPCR US28

    Amarandi, R., Lückmann, Michael, Melynis, M., Jakobsen, M. H., Fallah, Z., Spiess, Katja, Hjortø, Gertrud Malene, Pui, A., Frimurer, Thomas Michael & Rosenkilde, Mette, 2018, In : European Journal of Medicinal Chemistry. 155, p. 244-254

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Covalent attachment of antagonists to the a7 nicotinic acetylcholine receptor: synthesis and reactivity of substituted maleimides

    Ambrus, J. I., Halliday, J. I., Kanizaj, N., Absalom, N., Harpsøe, Kasper, Balle, T., Chebib, M. & McLeod, M. D., 7 Jul 2012, In : Chemical Communications. 48, 53, p. 6699-6701 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Effects of whole-body heat acclimation on cell injury and cytokine responses in peripheral blood mononuclear cells

    Amorim, F., Yamada, P., Robergs, R., Schneider, S. & Moseley, Pope Lloyd, Aug 2011, In : European Journal of Applied Physiology. 111, 8, p. 1609-18 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Binding of the Multimodal Antidepressant Drug Vortioxetine to the Human Serotonin Transporter

    Andersen, J., Ladefoged, L. K., Wang, Danyang, Kristensen, T. N. B., Bang-Andersen, B., Kristensen, Anders Skov, Schiøtt, B. & Strømgaard, Kristian, 18 Nov 2015, In : A C S Chemical Neuroscience. 6, 11, p. 1892-900 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Enhanced cerebral branched-chain amino acid metabolism in R6/2 mouse model of Huntington's disease

    Andersen, Jens Velde, Skotte, Niels Henning, Aldana Garcia, Blanca Irene, Nørremølle, Anne & Waagepetersen, Helle S., 2019, In : Cellular and Molecular Life Sciences. 76, 12, p. 2449-2461

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Protein kinase A stimulates Kv7.1 surface expression by regulating Nedd4-2-dependent endocytic trafficking

    Andersen, M. N., Hefting, L. L., Steffensen, Annette Buur, Schmitt, Nicole, Olesen, Søren-Peter, Olsen, Jesper Velgaard, Lundby, Alicia & Rasmussen, Hanne Borger, 15 Nov 2015, In : American Journal of Physiology: Cell Physiology. 309, 10, p. C693-C706 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    The derived allele of a novel intergenic variant at chromosome 11 associates with lower body mass index and a favorable metabolic phenotype in Greenlanders

    Lepola, Mette Andersen, Jørsboe, Emil, Skotte, L., Hanghøj, Kristian Ebbesen, Sandholt, C. H., Moltke, Ida, Grarup, Niels, Kern, T., Mahendran, Y., Søborg, B., Bjerregaard, P., Larsen, C. V. L., Dahl-Petersen, I. K., Tiwari, H. K., Feenstra, B., Koch, A., Wiener, H. W., Hopkins, S. E., Pedersen, Oluf Borbye, Melbye, Mads, Boyer, B. B., Jørgensen, M. E., Albrechtsen, Anders & Hansen, Torben, 2020, In : PLOS Genetics. 16, 1, 17 p., e1008544.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Protein Interaction Screening for the Ankyrin Repeats and Suppressor of Cytokine Signaling (SOCS) Box (ASB) Family Identify Asb11 as a Novel Endoplasmic Reticulum Resident Ubiquitin Ligase

    Andresen, C. A., Smedegaard, S., Sylvestersen, K. B., Svensson, C., Iglesias Gato, Diego, Cazzamali, G., Nielsen, T. K., Nielsen, Michael Lund & Flores Morales, A., 24 Jan 2014, In : The Journal of Biological Chemistry. 289, 4, p. 2043-2054 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    The ISCB Student Council Internship Program: Expanding computational biology capacity worldwide

    Anupama, J., Francescatto, M., Rahman, F., Fatima, N., DeBlasio, D., Shanmugam, A. K., Satagopam, V., Santos Delgado, Alberto, Kolekar, P., Michaut, M. & Guney, E., 2018, In : PLOS Computational Biology. 14, 1, p. 1-12 e1005802.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization

    Arking, D. E., Pulit, S. L., Crotti, L., van der Harst, P., Munroe, P. B., Koopmann, T. T., Sotoodehnia, N., Rossin, E. J., Morley, M., Wang, X., Johnson, A. D., Lundby, Alicia, Gudbjartsson, D. F., Noseworthy, P. A., Eijgelsheim, M., Bradford, Y., Tarasov, K. V., Dörr, M., Müller-Nurasyid, M., Lahtinen, A. M., Nolte, I. M., Smith, A. V., Bis, J. C., Isaacs, A., Newhouse, S. J., Evans, D. S., Post, W. S., Waggott, D., Lyytikäinen, L., Hicks, A. A., Eisele, L., Ellinghaus, D., Hayward, C., Navarro, P., Ulivi, S., Tanaka, T., Tester, D. J., Chatel, S., Gustafsson, S., Kumari, M., Morris, R. W., Naluai, A. T., Padmanabhan, S., Kluttig, A., Strohmer, B., Panayiotou, A. G., Torres, M., Knoflach, M., Olsen, Jesper Velgaard, Hansen, K. L. & CARe Consortium, C. C., 22 Jun 2014, In : Nature Genetics. 46, 8, p. 826-838 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    SignalP 5.0 improves signal peptide predictions using deep neural networks

    Armenteros, J. J. A., Tsirigos, Konstantinos, Sønderby, C. K., Petersen, T. N., Winther, Ole, Brunak, Søren, von Heijne, G. & Nielsen, H., 18 Feb 2019, In : Nature Biotechnology. 37, 4, p. 420-423

    Research output: Contribution to journalJournal articleCommunication

  23. Published

    Enterotypes of the human gut microbiome: [Plus]Corrigendum [Plus]Addendum

    Arumugam, Mani, Raes, J., Pelletier, E., Le Paslier, D., Yamada, T., Mende, D. R., Fernandes, G. R., Tap, J., Bruls, T., Batto, J., dos Santos, M. B. Q., Borruel, N., Casellas, F., Fernandez, L., Gautier, L., Hansen, Torben, Hattori, M., Hayashi, T., Kleerebezem, M., Kurokawa, K., Leclerc, M., Levenez, F., Manichanh, C., Nielsen, H. B., Nielsen, Trine, Pons, N., Poulain, J., Qin, J., Sicheritz-Ponten, T., Tims, S., Torrents, D., Ugarte, E., Zoetendal, E. G., Wang, Jun, Guarner, F., Pedersen, Oluf Borbye, de Vos, W. M., Brunak, Søren, Doré, J., Antolín, M., Artiguenave, F., Blottiere, H. M., Almeida, M., Brechot, C., Cara, C., Chervaux, C., Cultrone, A., Delorme, C., Denariaz, G., Kristiansen, Karsten & MetaHIT Consortium, M. C., 2011, In : Nature. 473, 7346, p. 174-180 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Contaminating viral sequences in high-throughput sequencing viromics: a linkage study of 700 sequencing libraries

    Asplund, M., Kjartansdóttir, K. R., Mollerup, S., Vinner, Lasse, Fridholm, H., Romero Herrera, Jose Alejandro, Friis-Nielsen, J., Hansen, T. A., Jensen, R. H., Nielsen, Ida Broman, Richter, S. R., Rey de la Iglesia, Alba, Matey-Hernandez, M. L., Alquezar-Planas, D. E., Olsen, Pernille Vibeke Selmer, Sicheritz-Pontén, Thomas, Willerslev, Eske, Lund, O., Brunak, Søren, Mourier, T., Nielsen, L. P., Izarzugaza, J. M. G. & Hansen, Anders Johannes, 2019, In : Clinical Microbiology and Infection. 25, 10, p. 1277-1285

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    A computational approach to chemical etiologies of diabetes

    Audouze, K. M. L., Brunak, Søren & Grandjean, P., 19 Sep 2013, In : Scientific Reports. 3, p. 2712 2712.

    Research output: Contribution to journalJournal articleResearchpeer-review

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