The NNF Center for Protein Research

  1. Published

    A lncRNA to repair DNA

    Lukas, Jiri & Altmeyer, M., Nov 2015, In : E M B O Reports. 16, 11, p. 1413-4 2 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  2. Published

    Jiri Lukas: Visualizing genome integrity maintenance. Interview by Caitlin Sedwick

    Lukas, Jiri, 9 Jul 2012, In : Journal of Cell Biology. 198, 1, p. 4-5 2 p.

    Research output: Contribution to journalJournal articleCommunication

  3. Published

    Molecular biology. Shielding broken DNA for a quick fix

    Lukas, Jiri & Lukas, Claudia, 8 Feb 2013, In : Science (New York, N.Y.). 339, 6120, p. 652-3 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Evidence of Extrapancreatic Glucagon Secretion in Man

    Lund, A., Bagger, J. I., Albrechtsen, Nicolai Jacob Wewer, Christensen, M., Grøndahl, M., Hartmann, Bolette, Mathiesen, Elisabeth, Hansen, C. P., Storkholm, J. H., van Hall, Gerrit, Rehfeld, Jens Frederik, Hornburg, D., Meissner, F., Mann, Matthias, Larsen, S., Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, Mar 2016, In : Diabetes. 65, 3, p. 585-597 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Phosphoproteomics taken to heart

    Lundby, Alicia & Olsen, Jesper Velgaard, 1 Sep 2013, In : Cell Cycle. 12, 17, p. 2707-2708 2 p.

    Research output: Contribution to journalEditorialResearchpeer-review

  6. Published

    GeLCMS for in-depth protein characterization and advanced analysis of proteomes

    Lundby, Alicia & Olsen, Jesper Velgaard, 1 Jan 2011, Gel-Free Proteomics Methods and Protocols. Vol. 753. p. 143-55 13 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  7. Published

    Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns

    Lundby, Alicia, Hansen, K. L., Weinert, B. T., Breinholt Bekker-Jensen, D., Secher, A., Skovgaard, T., Kelstrup, C., Dmytriyev, A., Choudhary, Chuna Ram, Lundby, C. & Olsen, Jesper Velgaard, 30 Aug 2012, In : Cell Reports. 2, 2, p. 419-431 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Hvordan når kvinderne toppen?

    Lundby, Alicia, Gerken, M., Jess, T. & Dahl, Tais Wittchen, 5 Nov 2013, In : Berlingske Tidende.

    Research output: Contribution to journalContribution to newspaper - Comment/debateCommunication

  9. Published

    Oncogenic Mutations Rewire Signaling Pathways by Switching Protein Recruitment to Phosphotyrosine Sites

    Lundby, Alicia, Franciosa, Giulia, Emdal, Kristina Bennet, Refsgaard, J. C., Gnosa, Sebastian Peter, Bekker-Jensen, D. B., Secher, A., Maurya, S. R., Paul, I., Mendez, B. L., Kelstrup, C. D., Francavilla, C., Kveiborg, Marie, Montoya, Guillermo, Jensen, Lars Juhl & Olsen, Jesper Velgaard, 2019, In : Cell. 179, 2, p. 543-560

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues

    Lundby, Alicia, Secher, A., Lage, K., Nordsborg, Nikolai Baastrup, Dmytriyev, A., Lundby, C. & Olsen, Jesper Velgaard, 6 Jun 2012, In : Nature Communications. 3, p. 1-10 10 p., Article 876.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    In Vivo Phosphoproteomics Analysis Reveals the Cardiac Targets of β-Adrenergic Receptor Signaling

    Lundby, Alicia, Andersen, M. N., Steffensen, Annette Buur, Horn, H., Kelstrup, C. D., Francavilla, C., Jensen, Lars Juhl, Schmitt, Nicole, Thomsen, Morten Bækgaard & Olsen, Jesper Velgaard, 4 Jun 2013, In : Science Signaling. 6, 278, p. rs11 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Biophysical characterization of the fluorescent protein voltage probe VSFP2.3 based on the voltage-sensing domain of Ci-VSP

    Lundby, Alicia, Akemann, W. & Knöpfel, T., 6 Aug 2010, In : European Biophysics Journal. 39, 12, p. 1625-1635 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Structural basis for KV7.1/KCNEx interactions in the IKs channel complex

    Lundby, Alicia, Tseng, G. & Schmitt, Nicole, 2010, In : Heart Rhythm. 7, 5, p. 708-713

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Annotation of loci from genome-wide association studies using tissue-specific quantitative interaction proteomics

    Lundby, Alicia, Rossin, E. J., Steffensen, Annette Buur, Acha, M. R., Newton-Cheh, C., Pfeufer, A., Lynch, S. N., Olesen, Søren-Peter, Brunak, Søren, Ellinor, P. T., Jukema, J. W., Trompet, S., Ford, I., Macfarlane, P. W., Krijthe, B. P., Hofman, A., Uitterlinden, A. G., Stricker, B. H., Nathoe, H. M., Spiering, W., Daly, M. J., Asselbergs, F. W., van der Harst, P., Milan, D. J., de Bakker, P. I. W., Hansen, K. L., Olsen, Jesper Velgaard & The QT Interval International GWAS Consortium (QT-IGC), T. Q. I. I. G. C. (., 22 Jun 2014, In : Nature Methods. 11, 8, p. 868-874 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Direct neuronal glucose uptake Heralds activity-dependent increases in cerebral metabolism

    Lundgaard, I., Li, B., Xie, L., Kang, H., Sanggaard, S., Haswell, J. D. R., Sun, W., Goldman, S., Blekot, S., Nielsen, Michael Lund, Takano, T., Deane, R. & Nedergaard, Maiken, 2015, In : Nature Communications. 6, 12 p., 6807.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Histone deacetylases 1 and 3 but not 2 mediate cytokine-induced beta cell apoptosis in INS-1 cells and dispersed primary islets from rats and are differentially regulated in the islets of type 1 diabetic children

    Lundh, M., Christensen, D. P., Damgaard Nielsen, M., Richardson, S. J., Dahllöf, M. S., Skovgaard, T., Berthelsen, J., Dinarello, C. A., Stevenazzi, A., Mascagni, P., Grunnet, Louise Groth, Morgan, N. G. & Mandrup-Poulsen, Thomas, 2012, In : Diabetologia. 55, 9, p. 2421-31

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Mechanisms preserving insulin action during high dietary fat intake

    Lundsgaard, Anne-Marie, Holm, J. B., Sjøberg, Kim A, Bojsen-Møller, K. N., Myrmel, L. S., Fjære, E., Jensen, Benjamin Anderschou Holbech, Nicolaisen, Trine Sand, Hingst, Janne Rasmuss, Hansen, S. L., Doll, S., Geyer, P. E., Deshmukh, Atul Shahaji, Holst, Jens Juul, Madsen, L., Kristiansen, Karsten, Wojtaszewski, Jørgen F P, Richter, Erik A. & Kiens, Bente, 2019, In : Cell Metabolism. 29, 1, p. 50-63, e1-e4 19 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Cultivation of HepG2.2.15 on Cytodex-3: higher yield of hepatitis B virus and less subviral particles compared to conventional culture methods

    Lupberger, J., Mund, Andreas, Kock, J. & Hildt, E., Oct 2006, In : Journal of Hepatology. 45, 4, p. 547-52 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Separation of the gluconeogenic and mitochondrial functions of pgc-1α through s6 kinase

    Lustig, Y., Ruas, J. L., Estall, J. L., Lo, J. C., Devarakonda, S., Laznik, D., Choi, J. H., Spiegelman, B. M., Ono, H. & Olsen, Jesper Velgaard, 15 Jun 2011, In : Genes & Development. 25, 12, p. 1232-1244 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    A versatile selection system for folding competent proteins using genetic complementation in a eukaryotic host.

    Lyngsø, C., Kjaerulff, S., Muller, S., Bratt, T., Mortensen, U. H. & Dal Degan, F., 2010, In : Protein Science. 19, 3, p. 579-592 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Structure-based discovery of novel US28 small molecule ligands with different modes of action

    Lückmann, Michael, Amarandi, R., Papargyri, N., Jakobsen, M. H., Ulven, Elisabeth Rexen, Jensen, Lars Juhl, Pui, A., Schwartz, Thue W., Rosenkilde, Mette & Frimurer, Thomas Michael, 2017, In : Chemical Biology & Drug Design. 89, 3, p. 289–296

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Molecular dynamics-guided discovery of an ago-allosteric modulator for GPR40/FFAR1

    Lückmann, Michael, Trauelsen, Mette, Bentsen, Marie Aare, Nissen, Tinne Amalie Damgaard, Martins, J., Fallah, Z., Nygaard, Mads Mørup, Papaleo, Elena, Lindorff-Larsen, Kresten, Schwartz, Thue W. & Frimurer, Thomas Michael, 2 Apr 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 14, p. 7123-7128

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Optimization of a heterologous mevalonate pathway through the use of variant HMG-CoA reductases

    Ma, S. M., Garcia, D. E., Redding-Johanson, A. M., Friedland, G. D., Chan, R., Batth, Tanveer Singh, Haliburton, J. R., Chivian, D., Keasling, J. D., Petzold, C. J., Lee, T. S. & Chhabra, S. R., Sep 2011, In : Metabolic Engineering. 13, 5, p. 588-97 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    HBO1 is required for the maintenance of leukaemia stem cells

    MacPherson, L., Anokye, J., Yeung, M. M., Lam, E. Y. N., Chan, Y., Weng, C., Yeh, P., Knezevic, K., Butler, M. S., Hoegl, A., Chan, K., Burr, M. L., Gearing, L. J., Willson, T., Liu, J., Choi, J., Yang, Y., Bilardi, R. A., Falk, H., Nghi Nguyen, Stupple, P. A., Peat, T. S., Zhang, M., De Silva, M., Carrasco-Pozo, C., Avery, V. M., Khoo, S., Dolezal, O., Dennis, M. L., Nuttall, S., Surjadi, R., Newman, J., Ren, B., Leaver, D. J., Sun, Y., Baell, J. B., Dovey, O., Vassiliou, G. S., Grebien, F., Dawson, S., Street, I. P., Monahan, B. J., Burns, C. J., Choudhary, Chuna Ram, Blewitt, M. E., Voss, A. K., Thomas, T. & Dawson, M. A., 2020, In : Nature. 577, 7789, p. 266-270

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Palaeoproteomic Profiling of Conservation Layers on a 14th Century Italian Wall Painting

    Mackie, Meaghan, Rüther, Patrick, Samodova, Diana, Di Gianvincenzo, Fabiana, Granzotto, C., Lyon, D., Peggie, D. A., Howard, H., Harrison, L., Jensen, Lars Juhl, Olsen, Jesper Velgaard & Cappellini, Enrico, 2018, In : Angewandte Chemie (International ed. in English). 57, 25, p. 7369-7374 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Biotin starvation causes mitochondrial protein hyperacetylation and partial rescue by the SIRT3-like deacetylase Hst4p

    Madsen, C. T., Sylvestersen, K. B., Young, C., Buch-Larsen, Sara Charlotte, Poulsen, J. W., Andersen, M. A., Palmqvist, E. A., Hey-Mogensen, M., Jensen, P. B., Treebak, Jonas Thue, Lisby, Michael & Nielsen, Michael Lund, 2015, In : Nature Communications. 6, 12 p., 7726.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    The impact of structural integrity and route of administration on the antibody specificity against three cow's milk allergens - a study in Brown Norway rats

    Madsen, J. L., Kroghsbo, S., Madsen, C. B., Pozdnyakova, I., Barkholt, V. & Bøgh, K. L., 2014, In : Clinical and Translational Allergy. 4, 12 p., 25.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Proteomics of Disulphide and Cysteine Oxidoreduction

    Maeda, K., Hägglund, Per Mårten, Finnie, C. & Svensson, B., 16 Nov 2007, Plant Proteomics. Wiley-Blackwell Publishing, Inc., p. 71-97 27 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  29. Published

    Identification, cloning and characterization of two thioredoxin h isoforms, HvTrxh1 and HvTrxh2, from the barley seed proteome

    Maeda, K., Finnie, C., Østergaard, Ole & Svensson, B., Jun 2003, In : European Journal of Biochemistry. 270, 12, p. 2633-43 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Crystal structures of barley thioredoxin h isoforms HvTrxh1 and HvTrxh2 reveal features involved in protein recognition and possibly in discriminating the isoform specificity

    Maeda, K., Hägglund, Per Mårten, Finnie, C., Svensson, B. & Henriksen, A., 1 Jun 2008, In : Protein Science. 17, 6, p. 1015-1024 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Structural Basis for Target Protein Recognition by the Protein Disulfide Reductase Thioredoxin

    Maeda, K., Hägglund, Per Mårten, Finnie, C., Svensson, B. & Henriksen, A., 1 Nov 2006, In : Structure. 14, 11, p. 1701-1710 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    TH2BS11ph histone mark is enriched in the unsynapsed axes of the XY body and predominantly associates with H3K4me3-containing genomic regions in mammalian spermatocytes

    Mahadevan, I. A., Pentakota, Satya Krishna, Roy, R., Bhaduri, U. & Satyanarayana Rao, M. R., 2019, In : Epigenetics & Chromatin. 12, 1, 23 p., 53.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Regulation of PCNA-protein interactions for genome stability

    Mailand, Niels, Gibbs-Seymour, I. & Bekker-Jensen, Simon Holst, May 2013, In : Nature Reviews. Molecular Cell Biology. 14, 5, p. 269-82 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    A genomic history of aboriginal Australia

    Malaspinas, A. S., Westaway, M. C., Muller, C. E., Sousa, V. C., Lao, O., Alves, I., Bergström, A., Athanasiadis, G., Cheng, J. Y., Crawford, J. E., Heupink, T. H., Macholdt, E., Peischl, S., Rasmussen, Simon, Schiffels, S., Subramanian, S., Wright, J. L., Albrechtsen, Anders, Barbieri, C., Dupanloup, I., Eriksson, A., Margaryan, Ashot, Moltke, Ida, Pugach, I., Korneliussen, Thorfinn Sand, Levkivskyi, I. P., Moreno Mayar, José Victor, Ni, S., Racimo, F., Sikora, Martin, Xue, Y., Aghakhanian, F. A., Brucato, N., Brunak, Søren, Campos, P., Clark, W., Ellingvåg, S., Fourmile, G., Gerbault, P., Injie, D., Koki, G., Leavesley, M., Logan, B., Lynch, A., Matisoo-Smith, E. A., McAllister, P. J., Mentzer, A. J., Metspalu, M., Migliano, A. B., Murgha, L., Phipps, M. E., Pomat, W., Reynolds, D., Ricaut, F., Siba, P., Thomas, M. G., Wales, T., Wall, C. M., Oppenheimer, S. J., Tyler-Smith, C., Durbin, R., Dortch, J., Manica, A., Schierup, M. H., Foley, R. A., Lahr, M. M., Bowern, C., Wall, J. D., Mailund, T., Stoneking, M., Nielsen, Rasmus, Sandhu, M. S., Excoffier, L., Lambert, D. M. & Willerslev, Eske, 2016, In : Nature. 538, 7624, p. 207-214 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Self-assembly of designed coiled coil peptides studied by small-angle X-ray scattering and analytical ultracentrifugation

    Malik, L., Nygaard, J., Christensen, Niels Johan, Thulstrup, Peter Waaben, Arleth, Lise, Jensen, Knud Jørgen & Streicher, W., 2013, In : Journal of Peptide Science. 19, 5, p. 283-292 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Downregulation of 5-HT7 Serotonin Receptors by the Atypical Antipsychotics Clozapine and Olanzapine. Role of Motifs in the C-Terminal Domain and Interaction with GASP-1

    Manfra, O., Van Craenenbroeck, K., Skieterska, K., Frimurer, Thomas Michael, Schwartz, Thue W., Levy, F. O. & Andressen, K. W., Jul 2015, In : A C S Chemical Neuroscience. 6, 7, p. 1206–1218 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    How unfinished business from S-phase affects mitosis and beyond

    Mankouri, H. W., Huttner, D. & Hickson, Ian David, 16 Oct 2013, In : EMBO Journal. 32, 20, p. 2661-71 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Proteomics for biomedicine: A half-completed journey

    Mann, Matthias, 1 Feb 2012, In : EMBO Molecular Medicine. 4, 2, p. 75-77 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    The Coming Age of Complete, Accurate, and Ubiquitous Proteomes

    Mann, Matthias, Kulak, N. A., Nagaraj, N. & Cox, J., 21 Feb 2013, In : Molecular Cell. 49, 4, p. 583-590 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    The ever expanding scope of electrospray mass spectrometry-a 30 year journey

    Mann, Matthias, 2019, In : Nature Communications. 10, 3744.

    Research output: Contribution to journalComment/debateResearch

  41. Published

    Development, use, application of novel TIMS-Tof system

    Mann, Matthias, 2019, In : Molecular & Cellular Proteomics. 18, 8, p. S20 1 p.

    Research output: Contribution to journalConference abstract in journalResearch

  42. Published

    Plenary Lecture Proteomics technologies for signaling, clinical applications

    Mann, Matthias, 2017, p. S62-S62.

    Research output: Contribution to conferenceConference abstract for conferenceCommunication

  43. Published

    Cryo-EM structures of a human ABCG2 mutant trapped in ATP-bound and substrate-bound states

    Manolaridis, I., Jackson, S. M., Taylor, Nicholas M I, Kowal, J., Stahlberg, H. & Locher, K. P., 2018, In : Nature. 563, 7731, p. 426-430 5 p.

    Research output: Contribution to journalLetterResearchpeer-review

  44. Published

    Self-hydroxylation of the splicing factor lysyl hydroxylase, JMJD6

    Mantri, M., Webby, C. J., Loik, N. D., Hamed, R. B., McDonough, M. A., McCullagh, J. S. O., Schofield, C. J., Wolf, A., Nielsen, Michael Lund & Böttger, A., 1 Jan 2012, In : MedChemComm. 3, 1, p. 80-85 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Identification of BRAF 3'UTR isoforms in melanoma

    Marranci, A., Tuccoli, A., Vitiello, M., Mercoledi, E., Sarti, S., Lubrano, S., Evangelista, M., Fogli, A., Valdes, C., Russo, Francesco, Dal Monte, M., Caligo, M. A., Pellegrini, M., Capobianco, E., Tsinoremas, N. & Poliseno, L., 1 Jan 2015, In : Journal of Investigative Dermatology. 135, 6, p. 1694-1697 4 p.

    Research output: Contribution to journalLetterResearchpeer-review

  46. Published

    Proteome-wide identification of the endogenous ADP-ribosylome of mammalian cells and tissue

    Martello, R., Leutert, M., Jungmichel, S., Bilan, V., Buch-Larsen, Sara Charlotte, Young, C., Hottiger, M. O. & Nielsen, Michael Lund, 1 Oct 2016, In : Nature Communications. 7, 13 p., 12917.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Effectiveness of a coordinated and tailored return-to-work intervention for sickness absence beneficiaries with mental health problems

    Martin, M., Nielsen, Michael Lund, Madsen, I., Petersen, S., Lange, Theis & Rugulies, R., 2013, In : Journal of Occupational Rehabilitation. 23, 4, p. 621-30 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Numb-dependent integration of pre-TCR and p53 function in T-cell precursor development

    Martin-Blanco, N. M., Checquolo, S., Del Gaudio, F., Palermo, R., Franciosa, Giulia, Di Marcotullio, L., Gulino, A., Canelles, M. & Screpanti, I., 1 Jan 2014, In : Cell Death and Disease. 5, e1472.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Loss of CBL E3-ligase activity in B-lineage childhood acute lymphoblastic leukaemia

    Martinelli, S., Checquolo, S., Consoli, F., Stellacci, E., Rossi, C., Silvano, M., Franciosa, Giulia, Flex, E., Cossu, C., De Luca, A., Foà, R., Cazzaniga, G., Biondi, A., Screpanti, I. & Tartaglia, M., 1 Oct 2012, In : British Journal of Haematology. 159, 1, p. 115-119 5 p.

    Research output: Contribution to journalLetterResearchpeer-review

  50. Published

    Direct effects of FGF21 on glucose uptake in human skeletal muscle: implications for type 2 diabetes and obesity

    Mashili, F. L., Austin, R. L., Deshmukh, Atul Shahaji, Fritz, T., Caidahl, K., Bergdahl, K., Zierath, Juleen R, Chibalin, A. V., Moller, D. E., Kharitonenkov, A. & Krook, A., Mar 2011, In : Diabetes - Metabolism: Research and Reviews (Print Edition). 27, 3, p. 286-97 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Benchmarking the HLA typing performance of Polysolver and Optitype in 50 Danish parental trios

    Matey-Hernandez, M. L., Danish Pan Genome Consortium, D. P. G. C., Brunak, Søren, Izarzugaza, J. M. G., Sørensen, L. M., Petersen, Bent, Sibbesen, J. A., Liu, S., Belling, Kirstine G, Have, C. T., Bork-Jensen, J., Sun, J., Hansen, Torben, Krogh, Anders, Sørensen, Thorkild I.A., Pedersen, Oluf Borbye, Wang, Jun, Eiberg, Hans Rudolf Lytchoff & Kristiansen, Karsten, 2018, In : BMC Bioinformatics. 19, p. 1-12 239.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    A two-step protein quality control pathway for a misfolded DJ-1 variant in fission yeast

    Mathiassen, S. G., Larsen, I. B., Poulsen, E. G., Madsen, C. T., Papaleo, Elena, Lindorff-Larsen, Kresten, Kragelund, Birthe Brandt, Nielsen, Michael Lund, Kriegenburg, F. & Hartmann-Petersen, Rasmus, 2015, In : The Journal of Biological Chemistry. 290, 34, p. 21141-21153 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Thermoascus aurantiacus is a promising source of enzymes for biomass deconstruction under thermophilic conditions

    McClendon, S. D., Batth, Tanveer Singh, Petzold, C. J., Adams, P. D., Simmons, B. A. & Singer, S. W., 28 Jul 2012, In : Biotechnology for Biofuels. 5, 1, p. 54

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    The ubiquitin-selective segregase VCP/p97 orchestrates the response to DNA double-strand breaks

    Meerang, M., Ritz, D., Paliwal, S., Garajova, Z., Bosshard, M., Mailand, Niels, Janscak, P., Hübscher, U., Meyer, H. & Ramadan, K., 2011, In : Nature Cell Biology. 13, 11, p. 1376-82 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    BoxCar acquisition method enables single-shot proteomics at a depth of 10,000 proteins in 100 minutes

    Meier, F., Geyer, P. E., Virreira Winter, S., Cox, J. & Mann, Matthias, 2018, In : Nature Methods. 15, 6, p. 440-448 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    Online parallel accumulation - serial fragmentation (PASEF) with a novel trapped ion mobility mass spectrometer

    Meier, F., Brunner, A., Koch, S., Koch, H., Lubeck, M., Krause, M., Goedecke, N., Decker, J., Kosinski, T., Park, M. A., Bache, N., Hoerning, O., Cox, J., Räther, O. & Mann, Matthias, 2018, In : Molecular and Cellular Proteomics. 17, 12, p. 2534-2545

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    Parallel accumulation - serial fragmentation combined with data-independent acquisition (diaPASEF)

    Meier, F., Brunner, A., Frank, M., Ha, A., Voytik, E., Kaspar-Schoenefeld, S., Lubeck, M., Raether, O., Aebersold, R., Collins, B. C., Roest, H. L. & Mann, Matthias, 2019, In : Molecular & Cellular Proteomics. 18, 8, p. S17 1 p.

    Research output: Contribution to journalConference abstract in journalResearch

  58. Published

    New histone supply regulates replication fork speed and PCNA unloading

    Mejlvang, J., Feng, Y., Alabert, C., Neelsen, K. J., Jasencakova, Zuzana, Zhao, X., Lees, M., Sandelin, Albin Gustav, Pasero, P., Lopes, M. & Groth, Anja, 6 Jan 2014, In : Journal of Cell Biology. 204, 1, p. 29-43 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    Dipeptidyl peptidase-4 inhibitors administered in combination with metformin result in an additive increase in the plasma concentration of active GLP-1

    Migoya, E. M., Bergeron, R., Miller, J. L., Snyder, R. N. K., Tanen, M., Hilliard, D., Weiss, B., Larson, P., Gutierrez, M., Jiang, G., Liu, F., Pryor, K. A., Yao, J., Zhu, L., Holst, Jens Juul, Deacon, Carolyn F., Herman, G., Thornberry, N., Amatruda, J., Williams-Herman, D., Wagner, J. A. & SinhaRoy, R., 1 Dec 2010, In : Clinical Pharmacology and Therapeutics. 88, 6, p. 801-8 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    RNAscClust: Clustering RNA sequences using structure conservation and graph based motifs

    Miladi, M., Junge, A., Costa, F., Seemann, Ernst Stefan, Havgaard, Jakob Hull, Gorodkin, Jan & Backofen, R., 2017, In : Bioinformatics. 33, 14, p. 2089-2096 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. Published

    Linear motif atlas for phosphorylation-dependent signaling

    Miller, M. L., Jensen, Lars Juhl, Diella, F., Jørgensen, Claus Bøttcher, Tinti, M., Li, L., Hsiung, M., Parker, S. A., Bordeaux, J., Sicheritz-Ponten, T., Olhovsky, M., Pasculescu, A., Alexander, J., Knapp, S., Blom, N., Bork, P., Li, S., Cesareni, G., Pawson, T., Turk, B. E., Yaffe, M. B., Brunak, Søren & Linding, R., 2008, In : Science signaling. 1, 35, p. ra2

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. Published

    Mutations in FGF17, IL17RD, DUSP6, SPRY4, and FLRT3 are identified in individuals with congenital hypogonadotropic hypogonadism

    Miraoui, H., Dwyer, A. A., Hughes, V. A., Sidis, Y., Pitteloud, N., Sykiotis, G. P., Plummer, L., Feng, B., Keefe, K., Crowley Jr., W. F., Seminara, S. B., Hall, J. E., Chung, W., Tsai, P., Beenken, A., Mohammadi, M., Clarke, J., Rubenstein, J., Pers, T. H., Dworzynski, P., Hansen, K. L., Niedziela, M., Raivio, T., Quinton, R., Kumanov, P., Young, J. F., Yialamas, M. A., Van Vliet, G. & Chanoine, J., 2 May 2013, In : American Journal of Human Genetics. 92, 5, p. 725-743 19 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. Published

    The role of HERC2 and RNF8 ubiquitin E3 ligases in the promotion of translesion DNA synthesis in the chicken DT40 cell line

    Mohiuddin, M., Kobayashi, S., Keka, I. S., Guilbaud, G., Sale, J., Narita, Takeo, Abdel-Aziz, H. I., Wang, X., Ogawa, S., Sasanuma, H., Chiu, R., Østergaard, Vibe Hallundbæk, Lisby, Michael & Takeda, S., Apr 2016, In : DNA Repair. 40, p. 67-76 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  64. Published

    Modulation of constitutive activity and signaling bias of the ghrelin receptor by conformational constraint in the second extracellular loop

    Mokrosinski, J., Frimurer, Thomas Michael, Sivertsen, B., Schwartz, Thue W. & Holst, Birgitte, Sep 2012, In : Journal of Biological Chemistry. 287, p. 33488-33502 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. Published

    Binding Mode of a Novel MPEP-Derived Metabotropic Glutamate Receptor Subtype 5 (mGluR5) NAM, 1,3-Bis(pyridin-2-ylethynyl)Benzene

    Molck, C., Harpsøe, Kasper, Gloriam, David E., Kaae, B. H., Jimenez, H. N., Uberti, M. A., Topiol, S., Clausen, Rasmus Prætorius, Madsen, Ulf, Nielsen, S. M., Mathiesen, Jesper M. & Bräuner-Osborne, Hans, Sep 2011, In : Current Neuropharmacology. 9, p. 43-43

    Research output: Contribution to journalConference abstract in journalResearch

  66. Published

    Structure of Csx1-cOA4 complex reveals the basis of RNA decay in Type III-B CRISPR-Cas

    Molina, Rafael, Stella, Stefano, Feng, M., Sofos, Nicholas Heelund, Jauniskis, V., Pozdnyakova, I., López-Méndez, B., She, Q. & Montoya, Guillermo, 2019, In : Nature Communications. 10, 14 p., 4302.

    Research output: Contribution to journalJournal articleResearchpeer-review

  67. Published

    Visualizing phosphodiester-bond hydrolysis by an endonuclease

    Molina, Rafael, Stella, Stefano, Redondo, P., Gomez, H., Marcaida, M. J., Orozco, M., Prieto, J. & Montoya, Guillermo, Jan 2015, In : Nature Structural and Molecular Biology. 22, 1, p. 65-72 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. Published

    Non-specific protein-DNA interactions control I-CreI target binding and cleavage

    Molina, Rafael, Redondo, P., Stella, Stefano, Marenchino, M., D'Abramo, M., Gervasio, F. L., Charles Epinat, J., Valton, J., Grizot, S., Duchateau, P., Prieto, J. & Montoya, Guillermo, 1 Aug 2012, In : Nucleic Acids Research. 40, 14, p. 6936-6945 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. Published

    Crystal structure of CbpF, a bifunctional choline-binding protein and autolysis regulator from Streptococcus pneumoniae

    Molina, Rafael, Gonzalez, Ana Valeria, Stelter, M., Pérez-Dorado, I., Kahn, R., Morales, M., Moscoso, M., Campuzano, S., Campillo, N. E., Mobashery, S., García, J. L., García, P. & Hermoso, J. A., Mar 2009, In : EMBO Reports. 10, 3, p. 246-51 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  70. Published

    Key Players in I-DmoI Endonuclease Catalysis Revealed from Structure and Dynamics

    Molina, Rafael, Besker, N., Marcaida, M. J., Montoya, Guillermo, Prieto, J. & D'Abramo, M., 8 Mar 2016, In : ACS chemical biology. 11, 5, p. 1401–1407

    Research output: Contribution to journalJournal articleResearchpeer-review

  71. Published

    Engineering a Nickase on the Homing Endonuclease I-DmoI Scaffold

    Molina, Rafael, Marcaida, M. J., Redondo, P., Marenchino, M., Duchateau, P., D'Abramo, M., Montoya, Guillermo & Prieto, J., 2015, In : The Journal of Biological Chemistry. 290, 30, p. 18534-18544 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  72. Published

    Crystal Structure of the Homing Endonuclease I-CvuI Provides a New Template for Genome Modification

    Molina, Rafael, Redondo, P., López-Méndez, B., Villate, M., Merino, N., Blanco, F. J., Valton, J., Grizot, S., Duchateau, P., Prieto, J. & Montoya, Guillermo, 27 Nov 2015, In : The Journal of Biological Chemistry. 290, 48, p. 28727-36 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  73. Published

    Crystallization and preliminary X-ray diffraction studies of choline-binding protein F from Streptococcus pneumoniae

    Molina, Rafael, Gonzalez, Ana Valeria, Moscoso, M., García, P., Stelter, M., Kahn, R. & Hermoso, J. A., 1 Sep 2007, In : Acta Crystallographica Section F: Structural Biology Communications. 63, Pt 9, p. 742-5 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  74. Published

    Characterization of gadolinium complexes for SAD phasing in macromolecular crystallography: application to CbpF

    Molina, Rafael, Stelter, M., Kahn, R. & Hermoso, J. A., Aug 2009, In : Acta crystallographica. Section D, Biological crystallography. 65, Pt 8, p. 823-31 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  75. Published

    Propionibacterium acnes: disease-causing agent or common contaminant? Detection in diverse patient samples by next-generation sequencing

    Mollerup, S., Friis-Nielsen, J., Vinner, Lasse, Hansen, T. A., Richter, S. R., Fridholm, E. M. H., Herrera, J. A. R., Lund, O., Brunak, Søren, Izarzugaza, J. M. G., Mourier, T., Nielsen, L. P. & Hansen, Anders Johannes, 2016, In : Journal of Clinical Microbiology. 54, 4, p. 980-987 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  76. Published

    Cutavirus in cutaneous malignant melanoma

    Mollerup, S., Fridholm, E. M. H., Vinner, Lasse, Kjartansdóttir, K. R., Friis-Nielsen, J., Asplund, M., Romero Herrera, Jose Alejandro, Steiniche, T., Mourier, T., Brunak, Søren, Willerslev, Eske, Izarzugaza, J. M. G., Hansen, Anders Johannes & Nielsen, L. P., Feb 2017, In : Emerging Infectious Diseases . 23, 2, p. 363-365 3 p.

    Research output: Contribution to journalLetterResearchpeer-review

  77. Published

    High-Throughput Sequencing-Based Investigation of Viruses in Human Cancers by Multienrichment Approach

    Mollerup, S., Asplund, M., Friis-Nielsen, J., Kjartansdóttir, K. R., Fridholm, H., Hansen, T. A., Romero Herrera, Jose Alejandro, Barnes, Christopher James, Jensen, R. H., Richter, S. R., Nielsen, Ida Broman, Pietroni, C., Alquezar-Planas, D. E., Rey de la Iglesia, Alba, Olsen, Pernille Vibeke Selmer, Rajpert-De Meyts, E., Groth-Pedersen, L., von Buchwald, Christian, Jensen, D. H., Gniadecki, R., Høgdall, Estrid Vilma Solyom, Langhoff, J. L., Pete, I., Vereczkey, I., Baranyai, Z., Dybkaer, K., Johnsen, H. E., Steiniche, T., Hokland, P., Rosenberg, Jacob, Baandrup, U., Sicheritz-Pontén, Thomas, Willerslev, Eske, Brunak, Søren, Lund, O., Mourier, T., Vinner, Lasse, Izarzugaza, J. M. G., Nielsen, L. P. & Hansen, Anders Johannes, 15 Oct 2019, In : The Journal of Infectious Diseases. 220, 8, p. 1312-1324

    Research output: Contribution to journalJournal articleResearchpeer-review

  78. Published

    How do CRISPR-Cas RNA-guided endonucleases cut specific DNA regions for Genome Editing?

    Montoya, Guillermo, 2018, In : Acta Crystallographica Section A: Foundations and Advances. 74, p. E3 1 p.

    Research output: Contribution to journalConference abstract in journalResearch

  79. Published

    Treacle controls the nucleolar response to rDNA breaks via TOPBP1 recruitment and ATR activation

    Mooser, C., Symeonidou, I., Leimbacher, P., Ribeiro, A., Shorrocks, A. K., Jungmichel, S., Buch-Larsen, Sara Charlotte, Knechtle, K., Jasrotia, A., Zurbriggen, D., Jeanrenaud, A., Leikauf, C., Fink, D., Nielsen, Michael Lund, Blackford, A. N. & Stucki, M., 8 Jan 2020, In : Nature Communications. 11, 1, p. 123

    Research output: Contribution to journalJournal articleResearchpeer-review

  80. Published

    XTACC3-XMAP215 association reveals an asymmetric interaction promoting microtubule elongation

    Mortuza, G. B., Cavazza, T., Garcia-Mayoral, M. F., Hermida, D., Peset, I., Pedrero, J. G., Merino, N., Blanco, F. J., Lyngsø, J., Bruix, M., Pedersen, J. S., Vernos, I. & Montoya, Guillermo, 29 Sep 2014, In : Nature Communications. 5, p. 1-12 12 p., 5072.

    Research output: Contribution to journalJournal articleResearchpeer-review

  81. Published

    Molecular basis of Tousled-Like Kinase 2 activation

    Mortuza, G. B., Hermida, D., Pedersen, A., Segura-Bayona, S., López-Méndez, B., Redondo, P., Rüther, Patrick, Pozdnyakova, I., Garrote, A. M., Muñoz, I. G., Villamor-Payà, M., Jauset, C., Olsen, Jesper Velgaard, Stracker, T. H. & Montoya, Guillermo, 2018, In : Nature Communications. 9, 1, p. 2535 2535.

    Research output: Contribution to journalJournal articleResearchpeer-review

  82. Published

    The deubiquitylating enzyme USP44 counteracts the DNA double-strand break response mediated by the RNF8 and RNF168 ubiquitin ligases

    Mosbech, A., Lukas, Claudia, Bekker-Jensen, Simon Holst & Mailand, Niels, 24 Apr 2013, In : Journal of Biological Chemistry. 288, p. 16579-16587 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  83. Published

    DVC1 (C1orf124) is a DNA damage-targeting p97 adaptor that promotes ubiquitin-dependent responses to replication blocks

    Mosbech, A., Gibbs-Seymour, I., Kagias, K., Thorslund, T., Beli, P., Povlsen, L., Nielsen, Sofie Vincents, Smedegaard, S., Sedgwick, G., Lukas, Claudia, Hartmann-Petersen, Rasmus, Lukas, Jiri, Choudhary, Chuna Ram, Pocock, R. D. J., Bekker-Jensen, Simon Holst & Mailand, Niels, 2012, In : Nature Structural and Molecular Biology. 19, 11, p. 1084-92 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  84. Published

    Identifying Sepsis Phenotypes

    Moseley, Pope Lloyd & Brunak, Søren, 2019, In : J A M A: The Journal of the American Medical Association. 322, 14, p. 1416-1417 2 p.

    Research output: Contribution to journalComment/debateResearch

  85. Published

    A review of sex differences in immune function after aerobic exercise.

    Moseley, Pope Lloyd, 2011, In : Exercise Immunology Review.

    Research output: Contribution to journalJournal articleResearchpeer-review

  86. Published

    Cellular and molecular mechanisms of heat stress-induced up-regulation of occludin protein expression: regulatory role of heat shock factor-1

    Moseley, Pope Lloyd, 2008, In : American Journal of Pathology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  87. Published

    Effect of heat acclimation on heat shock protein 72 and interleukin-10 in humans

    Moseley, Pope Lloyd, 2007, In : Journal of Applied Physiology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  88. Published

    Heat shock protein 72 response to exercise in humans

    Moseley, Pope Lloyd, 2008, In : Sports Medicine.

    Research output: Contribution to journalJournal articleResearchpeer-review

  89. Published

    Activation of heat-shock response by an adenovirus is essential for virus replication

    Moseley, Pope Lloyd, 2000, In : Nature.

    Research output: Contribution to journalJournal articleResearchpeer-review

  90. Published

    Heat shock protein 70 and glycoprotein 96 are differentially expressed on the surface of malignant and nonmalignant breast cells

    Moseley, Pope Lloyd, 2006, In : Cell Stress & Chaperones.

    Research output: Contribution to journalJournal articleResearchpeer-review

  91. Published

    Thermotolerance and heat acclimation may share a common mechanism in humans

    Moseley, Pope Lloyd, 2011, In : Am. J. Physiol. Regulatory Integrative Comp. Physiol..

    Research output: Contribution to journalJournal articleResearchpeer-review

  92. Published

    Exercise increases serum Hsp72 in humans

    Moseley, Pope Lloyd, 2002, In : Cell Stress & Chaperones.

    Research output: Contribution to journalJournal articleResearchpeer-review

  93. Published

    Heat shock protein 70 regulates cellular redox status by modulating glutathione-related enzyme activities

    Moseley, Pope Lloyd, 2007, In : Cell Stress & Chaperones.

    Research output: Contribution to journalJournal articleResearchpeer-review

  94. Published

    Selected contribution: Hyperthermia-induced intestinal permeability and the role of oxidative and nitrosative stress

    Moseley, Pope Lloyd, 2002, In : Journal of Applied Physiology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  95. Published

    TOPBP1 regulates RAD51 phosphorylation and chromatin loading and determines PARP inhibitor sensitivity

    Moudry, P., Watanabe, K., Wolanin, K. M., Bartkova, J., Wassing, I. E., Watanabe, S., Strauss, R., Pedersen, R. T., Østergaard, Vibe Hallundbæk, Lisby, Michael, Andújar-Sánchez, M., Maya-Mendoza, A., Esashi, F., Lukas, Jiri & Bartek, J., 2016, In : The Journal of Cell Biology. 212, 3, p. 281-288 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  96. Published

    New functionalities in the TCGAbiolinks package for the study and integration of cancer data from GDC and GTEx

    Mounir, M., Lucchetta, M., Silva, T. C., Olsen, C., Bontempi, G., Chen, X., Noushmehr, H., Colaprico, A. & Papaleo, Elena, 2019, In : PLOS Computational Biology. 15, 3, 18 p., e1006701.

    Research output: Contribution to journalJournal articleResearchpeer-review

  97. Published

    Specifying RNA-Binding Regions in Proteins by Peptide Cross-Linking and Affinity Purification

    Mullari, Meeli, Lyon, D., Jensen, Lars Juhl & Nielsen, Michael Lund, 2017, In : Journal of Proteome Research. 16, 8, p. 2762-2772 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  98. Published

    eggNOG v2.0: extending the evolutionary genealogy of genes with enhanced non-supervised orthologous groups, species and functional annotations

    Muller, J., Szklarczyk, D., Julien, P., Letunic, I., Roth, A., Kuhn, M., Powell, S., von Mering, C., Doerks, T., Jensen, Lars Juhl & Bork, P., 1 Jan 2010, In : Nucleic Acids Symposium Series. 38, Database issue, p. D190-5

    Research output: Contribution to journalJournal articleResearchpeer-review

  99. Published

    SPOC1 modulates DNA repair by regulating key determinants of chromatin compaction and DNA damage response

    Mund, Andreas, Schubert, T., Staege, H., Kinkley, S., Reumann, K., Kriegs, M., Fritsch, L., Battisti, V., Ait-Si-Ali, S., Hoffbeck, A., Soutoglou, E. & Will, H., Dec 2012, In : Nucleic Acids Research. 40, 22, p. 11363-79 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  100. Published

    From Phosphosites to Kinases

    Munk, S., Refsgaard, J. C., Olsen, Jesper Velgaard & Jensen, Lars Juhl, 2016, Phospho-Proteomics: Methods and Protocols. Stechow, L. V. (ed.). Springer, Vol. 1355. p. 307-21 15 p. (Methods in molecular biology (Clifton, N.J.)).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

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