The NNF Center for Protein Research

  1. Published

    Proteome and Phosphoproteome Changes Associated with Prognosis in Acute Myeloid Leukemia

    Aasebø, E., Berven, F. S., Bartaula-Brevik, S., Stokowy, T., Hovland, R., Vaudel, M., Døskeland, S. O., McCormack, E., Batth, Tanveer Singh, Olsen, Jesper Velgaard, Bruserud, Ø., Selheim, F. & Hernandez-Valladares, M., 2020, In : Cancers. 12, 3, 26 p., 709.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    α4βδ GABA receptors are high-affinity targets for γ-hydroxybutyric acid (GHB)

    Absalom, N., Karim, N., Eghorn, L. F., Villumsen, I. S., Bay, T., Bräuner-Osborne, Hans, Frølund, Bente, Clausen, Rasmus Prætorius, Olsen, Jesper Velgaard, Knudsen, Gitte Moos, Chebib, M. & Wellendorph, Petrine, 14 Aug 2012, In : Proceedings of the National Academy of Sciences USA (PNAS). 109, 33, p. 13404-13409 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Covalent Trapping of Methyllycaconitine at the α4-α4 Interface of the α4β2 Nicotinic Acetylcholine Receptor: ANTAGONIST BINDING SITE AND MODE OF RECEPTOR INHIBITION REVEALED

    Absalom, N. L., Quek, G., Lewis, T. M., Qudah, T., von Arenstorff, I., Ambrus, J. I., Harpsøe, Kasper, Karim, N., Balle, T., McLeod, M. D. & Chebib, M., 13 Sep 2013, In : The Journal of Biological Chemistry. 288, 37, p. 26521-32 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Regulation of ETAA1-mediated ATR activation couples DNA replication fidelity and genome stability

    Achuthankutty, D., Thakur, Roshan Singh, Haahr, Peter Thorlund, Hoffmann, Saskia, Drainas, A. P., Bizard, Anna Helene, Weischenfeldt, Joachim Lütken, Hickson, Ian David & Mailand, Niels, 2019, In : The Journal of Cell Biology. 218, 12, 11 p., 3943.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    E4 ligase-specific ubiquitination hubs coordinate DNA double-strand-break repair and apoptosis

    Ackermann, Leena, Schell, M., Pokrzywa, W., Kevei, É., Gartner, A., Schumacher, B. & Hoppe, T., Nov 2016, In : Nature Structural & Molecular Biology. 23, 11, p. 995-1002 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Paradoxical resistance of multiple myeloma to proteasome inhibitors by decreased levels of 19S proteasomal subunits

    Acosta-Alvear, D., Cho, M. Y., Wild, T., Buchholz, T. J., Lerner, A. G., Simakova, O., Hahn, J., Korde, N., Landgren, O., Maric, I., Choudhary, Chuna Ram, Walter, P., Weissman, J. S. & Kampmann, M., 1 Sep 2015, In : eLife. 4, p. 1-19 e08153.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    The AAA-ATPase VCP/p97 promotes 53BP1 recruitment by removing L3MBTL1 from DNA double-strand breaks

    Acs, K., Luijsterburg, M. S., Ackermann, Leena, Salomons, F. A., Hoppe, T. & Dantuma, N. P., 27 Nov 2011, In : Nature Structural & Molecular Biology. 18, 12, p. 1345-50 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Mass-spectrometric exploration of proteome structure and function

    Aebersold, R. & Mann, Matthias, 15 Sep 2016, In : Nature. 537, 7620, p. 347-55 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Analysis of Time-Series Gene Expression Data to Explore Mechanisms of Chemical-Induced Hepatic Steatosis Toxicity

    Aguayo Orozco, Alejandro, Bois, F. Y., Brunak, Søren & Taboureau, Olivier Thierry, 2018, In : Frontiers in Genetics. 9, p. 1-15 396.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    The use of systems biology in chemical risk assessment

    Aguayo Orozco, Alejandro, Taboureau, Olivier Thierry & Brunak, Søren, 2019, In : Current Opinion in Toxicology. 15, p. 48-54 7 p.

    Research output: Contribution to journalReviewResearchpeer-review

  11. Published

    sAOP: linking chemical stressors to adverse outcomes pathway networks

    Aguayo Orozco, Alejandro, Audouze, K., Siggaard, T., Barouki, R., Brunak, Søren & Taboureau, Olivier Thierry, 2019, In : Bioinformatics. 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Rare truncating variants in the sarcomeric protein titin associate with familial and early-onset atrial fibrillation

    Ahlberg, G., Refsgaard, L., Lundegaard, Pia Rengtved, Andreasen, L., Ranthe, M. F., Linscheid, N., Nielsen, J. B., Melbye, Mads, Haunsø, Stig, Sajadieh, Ahmad, Camp, L., Olesen, Søren-Peter, Rasmussen, Simon, Lundby, Alicia, Ellinor, P. T., Holst, A. G., Svendsen, Jesper Hastrup & Olesen, Morten Steen Salling, 2018, In : Nature Communications. 9, 1, 11 p., 4316.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    How well do force fields capture the strength of salt bridges in proteins?

    Ahmed, Mustapha Carab Hussein, Papaleo, Elena & Lindorff-Larsen, Kresten, 2018, In : PeerJ. 6, 17 p., 4967.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Genome-wide association study identifies three novel genetic markers associated with elite endurance performance

    Ahmetov, I., Kulemin, N., Popov, D., Naumov, V., Akimov, E., Bravy, Y., Egorova, E., Galeeva, A., Generozov, E., Kostryukova, E., Larin, A., Mustafina, L., Ospanova, E., Pavlenko, A., Starnes, L. M., Żmijewski, P., Alexeev, D., Vinogradova, O. & Govorun, V., 2015, In : Biology of Sport. 32, 1, p. 3-9 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    SDCCAG8 Interacts with RAB Effector Proteins RABEP2 and ERC1 and Is Required for Hedgehog Signaling

    Airik, R., Schueler, M., Airik, M., Cho, J., Ulanowicz, K. A., Porath, J. D., Hurd, T. W., Bekker-Jensen, Simon Holst, Schrøder, J. M., Andersen, J. S. & Hildebrandt, F., 2016, In : P L o S One. 11, 5, 19 p., e0156081.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Renal-Retinal Ciliopathy Gene Sdccag8 Regulates DNA Damage Response Signaling

    Airik, R., Slaats, G. G., Guo, Z., Weiss, A., Khan, N., Ghosh, A., Hurd, T. W., Bekker-Jensen, Simon Holst, Schrøder, J. M., Elledge, S. J., Andersen, J. S., Kispert, A., Castelli, M., Boletta, A., Giles, R. H. & Hildebrandt, F., Nov 2014, In : Journal of the American Society of Nephrology:JASN. 25, 11, p. 2573-83 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    UbiSite approach for comprehensive mapping of lysine and N-terminal ubiquitination sites

    Akimov, V., Barrio-Hernandez, I., Hansen, S. V. F., Hallenborg, P., Pedersen, A., Bekker-Jensen, D. B., Puglia, M., Christensen, S. D. K., Vanselow, J. T., Nielsen, M. M., Kratchmarova, I., Kelstrup, C. D., Olsen, Jesper Velgaard & Blagoev, B., 2018, In : Nature Structural & Molecular Biology. 25, p. 631-640 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Structure and dynamics of mesophilic variants from the homing endonuclease I-DmoI

    Alba, J., Marcaida, M. J., Prieto, J., Montoya, Guillermo, Molina, Rafael & D'Abramo, M., Dec 2017, In : Journal of Computer - Aided Molecular Design. 31, 12, p. 1063-1072 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Prediction of human drug-induced liver injury (DILI) in relation to oral doses and blood concentrations

    Albrecht, W., Kappenberg, F., Brecklinghaus, T., Stoeber, R., Marchan, R., Zhang, M., Ebbert, K., Kirschner, H., Grinberg, M., Leist, M., Moritz, W., Cadenas, C., Ghallab, A., Reinders, J., Vartak, N., van Thriel, C., Golka, K., Tolosa, L., Castell, J. V., Damm, G., Seehofer, D., Lampen, A., Braeuning, A., Buhrke, T., Behr, A., Oberemm, A., Gu, X., Kittana, N., van de Water, B., Kreiling, R., Fayyaz, S., van Aerts, L., Smedsrød, B., Ellinger-Ziegelbauer, H., Steger-Hartmann, T., Gundert-Remy, U., Zeigerer, A., Ullrich, A., Runge, D., Lee, S. M. L., Schiergens, T. S., Kuepfer, L., Aguayo Orozco, Alejandro, Sachinidis, A., Edlund, K., Gardner, I., Rahnenführer, J. & Hengstler, J. G., 2019, In : Archives of Toxicology. 93, 6, p. 1609-1637 29 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Glucagon receptor signaling in metabolic diseases

    Albrechtsen, Nicolai Jacob Wewer, 2018, In : Peptides. 100, p. 42-47

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Circulating Glucagon 1-61 Regulates Blood Glucose by Increasing Insulin Secretion and Hepatic Glucose Production

    Albrechtsen, Nicolai Jacob Wewer, Kuhre, Rune Ehrenreich, Hornburg, D., Jensen, C. Z., Hornum, Mads, Dirksen, C., Svane, M., Gasbjerg, Lærke Smidt, Jorgensen, N. B., Gabe, Maria Buur Nordskov, Balk-Moller, E., Albrechtsen, Reidar, Winther-Sørensen, Marie, Galsgaard, Katrine Douglas, Meissner, F., Jorsal, T., Lund, A., Vilsbøll, Tina, Eliasen, R., Bojsen-Moller, K. N., Idorn, T., Deacon, Carolyn F., Knop, Filip Krag, Rosenkilde, Mette, Hartmann, Bolette, Feldt-Rasmussen, Bo, Mann, Matthias, Madsbad, Sten & Holst, Jens Juul, Nov 2017, In : Cell Reports. 21, 6, p. 1452-1460

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    ADAM12-mediated shedding of basigin controls the subcellular localization and lactate transport of MCT4 and enhances collagen degradation in cancer cells: [Meeting Abstract}

    Albrechtsen, Reidar, Albrechtsen, Nicolai Jacob Wewer & Kveiborg, Marie, 2018, In : International Journal of Experimental Pathology. 99, 6, p. A25-A25

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  23. Published

    Assembly of Francisella novicida Cpf1 endonuclease in complex with guide RNA and target DNA

    Alcón, P., Montoya, Guillermo & Stella, Stefano, 1 Jul 2017, In : Acta Crystallographica Section F: Structural Biology Communications. 73, Pt 7, p. 409-415 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Suppressor of cytokine signaling 2 (SOCS2) deletion protects against multiple low dose streptozotocin-induced type 1 diabetes in adult male mice

    Alkharusi, A., Mirecki-Garrido, M., Ma, Z., Flores-Morales, A., Nyström, T., Castrillo, A., Bjorklund, A., Norstedt, G. & Fernández-Perez, L., Apr 2016, In : Hormone Molecular Biology and Clinical Investigation. 26, 1, p. 67-76 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Population genomics of bronze age Eurasia

    Allentoft, Morten Erik, Sikora, Martin, Sjogren, K., Rasmussen, S., Rasmussen, M., Stenderup, J., Damgaard, P. D. B., Schroeder, Hannes, Ahlstrom, T., Vinner, Lasse, Malaspinas, A. S., Margaryan, Ashot, Higham, T., Chivall, D., Lynnerup, Niels, Harvig, L. L., Baron, J., Della Casa, P., Dabrowski, P., Duffy, P. R., Ebel, A. V., Epimakhov, A., Frei, K., Furmanek, M., Gralak, T., Gromov, A., Gronkiewicz, S., Grupe, G., Hajdu, T., Jarysz, R., Khartanovich, V., Khokhlov, A., Kiss, V., Kolar, J., Kriiska, A., Lasak, I., Longhi, C., McGlynn, G., Merkevicius, A., Merkyte, I., Metspalu, M., Mkrtchyan, R., Moiseyev, V., Paja, L., Palfi, G., Pokutta, D., Pospieszny, L., Price, T. D., Saag, L., Sablin, M., Shishlina, N., Smrcka, V., Soenov, V. I., Szeverenyi, V., Toth, G., Trifanova, S. V., Varul, L., Vicze, M., Yepiskoposyan, L., Zhitenev, V., Orlando, L. A. A., Sicheritz-Ponten, T., Brunak, Søren, Nielsen, Rasmus, Kristiansen, K. & Willerslev, Eske, 2015, In : Nature Genetics. 522, 7555, p. 167-172 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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