Protein Structure and Function Program

  1. 2019
  2. Published

    High-Resolution Structure of Cas13b and Biochemical Characterization of RNA Targeting and Cleavage. / Slaymaker, Ian M; Mesa, Pablo; Kellner, Max J; Kannan, Soumya; Brignole, Edward; Koob, Jeremy; Feliciano, Patricia R; Stella, Stefano; Abudayyeh, Omar O; Gootenberg, Jonathan S; Strecker, Jonathan; Montoya, Guillermo; Zhang, Feng.

    In: Cell Reports, Vol. 26, No. 13, 26.03.2019, p. 3741-3751.e5.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Molecular architecture of the Jumonji C family histone demethylase KDM5B. / Dorosz, Jerzy; Kristensen, Line Hyltoft; Aduri, Nanda G; Mirza, Osman; Lousen, Rikke; Bucciarelli, Saskia; Mehta, Ved; Sellés-Baiget, Selene; Solbak, Sara Marie Øie; Bach, Anders; Mesa, Pablo; Hernandez, Pablo Alcon; Montoya, Guillermo; Nguyen, Tam T T N; Rand, Kasper D; Boesen, Thomas; Gajhede, Michael.

    In: Scientific Reports, Vol. 9, No. 1, 11.03.2019, p. 4019.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. E-pub ahead of print
  5. Published

    Structure and transformation of bacteriophage A511 baseplate and tail upon infection of Listeria cells. / Guerrero-Ferreira, Ricardo C.; Hupfeld, Mario; Nazarov, Sergey; Taylor, Nicholas M. I.; Shneider, Mikhail M.; Obbineni, Jagan M.; Loessner, Martin J.; Ishikawa, Takashi; Klumpp, Jochen; Leiman, Petr G.

    In: EMBO Journal, Vol. 38, No. 3, 2019.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. 2018
  7. Published

    Conformational Activation Promotes CRISPR-Cas12a Catalysis and Resetting of the Endonuclease Activity. / Stella, Stefano; Mesa, Pablo; Thomsen, Johannes; Paul, Bijoya; Alcón, Pablo; Jensen, Simon Bo; Saligram, Bhargav; Moses, Matias Emil; Hatzakis, Nikos S.; Montoya, Guillermo.

    In: Cell, Vol. 175, No. 7, 13.12.2018, p. 1856-1871.e21.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    A Type III-B Cmr effector complex catalyzes the synthesis of cyclic oligoadenylate second messengers by cooperative substrate binding. / Han, Wenyuan; Stella, Stefano; Zhang, Yan; Guo, Tong; Sulek, Karolina; Peng-Lundgren, Li; Montoya, Guillermo; She, Qunxin.

    In: Nucleic Acids Research, Vol. 46, No. 19, 2018, p. 10319-10330.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Contractile injection systems of bacteriophages and related systems. / Taylor, Nicholas M.I.; van Raaij, Mark J.; Leiman, Petr G.

    In: Molecular Microbiology, Vol. 108, No. 1, 2018, p. 6-15.

    Research output: Contribution to journalReviewResearchpeer-review

  10. Published

    Cryo-EM structures of a human ABCG2 mutant trapped in ATP-bound and substrate-bound states. / Manolaridis, Ioannis; Jackson, Scott M.; Taylor, Nicholas M.I.; Kowal, Julia; Stahlberg, Henning; Locher, Kaspar P.

    In: Nature, Vol. 563, No. 7731, 2018, p. 426-430.

    Research output: Contribution to journalLetterResearchpeer-review

  11. Published

    Extreme disorder in an ultrahigh-affinity protein complex. / Borgia, Alessandro; Borgia, Madeleine B.; Bugge, Katrine Østergaard; Kissling, Vera M.; Heidarsson, Pétur O.; Fernandes, Catarina B.; Sottini, Andrea; Soranno, Andrea; Buholzer, Karin J.; Nettels, Daniel; Kragelund, Birthe Brandt; Best, Robert B.; Schuler, Benjamin.

    In: Nature, Vol. 555, 2018, p. 61-66.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Molecular basis of Tousled-Like Kinase 2 activation. / Mortuza, Gulnahar B.; Hermida, Dario; Pedersen, Anna-Kathrine; Segura-Bayona, Sandra; López-Méndez, Blanca; Redondo, Pilar; Rüther, Patrick; Pozdnyakova, Irina; Garrote, Ana M; Muñoz, Inés G; Villamor-Payà, Marina; Jauset, Cristina; Olsen, Jesper V.; Stracker, Travis H.; Montoya, Guillermo.

    In: Nature Communications, Vol. 9, No. 1, 2535, 2018, p. 2535.

    Research output: Contribution to journalJournal articleResearchpeer-review

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