Disease Systems Biology Program

  1. 2019
  2. Published

    Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology

    Spracklen, C. N., Karaderi, Tugce, Yaghootkar, H., Schurmann, C., Fine, R. S., Kutalik, Z., Preuss, M. H., Lu, Y., Wittemans, L. B. L., Adair, L. S., Allison, M., Amin, N., Auer, P. L., Bartz, T. M., Blüher, M., Boehnke, M., Borja, J. B., Bork-Jensen, J., Broer, L., Chasman, D. I., Chen, Y. D. I., Chirstofidou, P., Demirkan, A., van Duijn, C. M., Feitosa, M. F., Garcia, M. E., Graff, M., Grallert, H., Grarup, Niels, Guo, X., Haesser, J., Hansen, Torben, Harris, T. B., Highland, H. M., Hong, J., Ikram, M. A., Ingelsson, E., Jackson, R., Jousilahti, P., Kähönen, M., Kizer, J. R., Kovacs, P., Kriebel, J., Laakso, M., Lange, L. A., Lehtimäki, T., Li, J., Lind, L., Oskari Kilpeläinen, Tuomas, Loos, R. J. F. & Mohlke, K. L., 2019, In : American Journal of Human Genetics. 105, 1, p. 15-28 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Genetic studies of abdominal MRI data identify genes regulating hepcidin as major determinants of liver iron concentration

    Wilman, H. R., Parisinos, C. A., Atabaki-Pasdar, N., Kelly, M., Thomas, E. L., Neubauer, S., Jennison, C., Ehrhardt, B., Baum, P., Schoelsch, C., Freijer, J., Grempler, R., Graefe-Mody, U., Hennige, A., Dings, C., Lehr, T., Scherer, N., Sihinecich, I., Pattou, F., Raverdi, V., Caiazzo, R., Torres, F., Verkindt, H., Mari, A., Tura, A., Giorgino, T., Bizzotto, Froguel, P., Brorsson, Caroline Anna, Brunak, Søren, De Masi, F., Pedersen, H., Banasik, Karina, Thomas, C., Lundgaard, Agnete Troen, Nielsen, A., Mazzoni, Gianluca, Karaderi, Tugce, Rasmussen, Simon, Johansen, Joachim, Allesøe, Rosa Lundbye, Arumugam, Mani, Allin, Kristine Højgaard, Hansen, Torben, Hansen, Tue Haldor, Jonsson, Anna Elisabet, Pedersen, Oluf Borbye, Dutta, Avirup, Vogt, J., drb459, drb459 & IMI-DIRECT consortium, I. C., 2019, In : Journal of Hepatology. 71, 3, p. 594-602 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    HDX-Viewer: interactive 3D visualization of hydrogen-deuterium exchange data

    Bouyssie, D., Lesne, J., Locard-Paulet, Marie, Albigot, R., Burlet-Schiltz, O. & Marcoux, J., 2019, In : Bioinformatics. 35, 24, p. 5331-5333 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Heterogeneity in the perirenal region of humans suggests presence of dormant brown adipose tissue that contains brown fat precursor cells

    Jespersen, N. Z., Feizi, A., Andersen, E. S., Heywood, S., Hattel, H. B., Daugaard, S., Peijs, Lone, Bagi, P., Feldt-Rasmussen, Bo, Schultz, H. S., Hansen, N. S., Krogh-Madsen, Rikke, Pedersen, Bente Klarlund, Petrovic, N., Nielsen, S. & Schéele, Camilla Charlotte, 2019, In : Molecular Metabolism. 24, p. 30-43 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Identification of Disease-miRNA Networks Across Different Cancer Types Using SWIM

    Fiscon, G., Conte, F., Farina, L., Pellegrini, M., Russo, Francesco & Paci, P., 2019, MicroRNA Target Identification: Methods and Protocols. Laganà, A. (ed.). Humana Press, p. 169-181 13 p. (Methods in Molecular Biology, Vol. 1970).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  7. Published

    Identification of hyper-rewired genomic stress non-oncogene addiction genes across 15 cancer types

    Hjaltelin, Jessica Xin, Izarzugaza, J. M. G., Jensen, Lars Juhl, Russo, Francesco, Westergaard, David & Brunak, Søren, 2019, In : npj Systems Biology and Applications. 5, 10 p., 27.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Identifying Sepsis Phenotypes

    Moseley, Pope Lloyd & Brunak, Søren, 2019, In : J A M A: The Journal of the American Medical Association. 322, 14, p. 1416-1417 2 p.

    Research output: Contribution to journalComment/debateResearch

  9. Published

    Immunity and mental illness: findings from a Danish population-based immunogenetic study of seven psychiatric and neurodevelopmental disorders

    Nudel, R., Benros, M. E., Krebs, M. D., Allesøe, R. L., Lemvigh, C. K., Bybjerg-Grauholm, J., Børglum, A. D., Daly, M. J., Nordentoft, Merete, Mors, O., Hougaard, D. M., Mortensen, P. B., Buil, A., Werge, Thomas, Rasmussen, Simon & Thompson, W. K., 2019, In : European Journal of Human Genetics. 27, p. 1445-1455

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Improving Peptide-Spectrum Matching by Fragmentation Prediction Using Hidden Markov Models

    Kirik, U., Refsgaard, J. C. & Jensen, Lars Juhl, 2019, In : Journal of Proteome Research. 18, 6, p. 2385-2396

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Incorporating symptom data in longitudinal disease trajectories for more detailed patient stratification

    Lademann, M., zmw894, zmw894, Boeck Jensen, A. & Brunak, Søren, 2019, In : International Journal of Medical Informatics. 129, p. 107-113 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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