Disease Systems Biology Program

  1. 2019
  2. Published

    Selective autophagy maintains centrosome integrity and accurate mitosis by turnover of centriolar satellites

    Holdgaard, S. G., Cianfanelli, V., Pupo, E., Lambrughi, M., Lubas, M., Nielsen, J. C., Eibes, S., Maiani, E., Harder, L. M., Wesch, N., Foged, M. M., Maeda, K., Nazio, F., de la Ballina, L. R., Dötsch, V., Brech, A., Frankel, Lisa, Jäättelä, M., Locatelli, F., Barisic, Marin, Andersen, J. S., Bekker-Jensen, Simon Holst, Lund, Anders H., Rogov, V. V., Papaleo, Elena, Lanzetti, L., De Zio, D. & Cecconi, F., 2019, In : Nature Communications. 10, 1, p. 1-19 19 p., 4176.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    A large-cohort, longitudinal study determines pre-cancer disease routes across different cancer types

    Hjaltelin, Jessica Xin, Helleberg, M., Jensen, A. B., Brunak, Søren & Lundgren, Jens, 2019, In : Cancer Research. 79, 4, p. 864-872

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    eggNOG 5.0: a hierarchical, functionally and phylogenetically annotated orthology resource based on 5090 organisms and 2502 viruses

    Huerta-Cepas, J., Szklarczyk, D., Heller, D., Hernández-Plaza, A., Forslund, S. K., Cook, H., Mende, D. R., Letunic, I., Rattei, T., Jensen, Lars Juhl, von Mering, C. & Bork, P., 2019, In : Nucleic Acids Research. 47, D1, p. D309-D314 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    The bio.tools registry of software tools and data resources for the life sciences

    Ison, J., Ienasescu, H., Chmura, Piotr Jaroslaw, Rydza, E., Ménager, H., Kalaš, M., Schwämmle, V., Grüning, B., Beard, N., Lopez, R., Duvaud, S., Stockinger, H., Persson, B., Vařeková, R. S., Raček, T., Vondrášek, J., Peterson, H., Salumets, A., Jonassen, I., Hooft, R., Nyrönen, T., Valencia, A., Capella, S., Gelpí, J., Zambelli, F., Savakis, B., Leskošek, B., Rapacki, K., Blanchet, C., Jimenez, R., Oliveira, A., Vriend, G., Collin, O., van Helden, J., Løngreen, P. & Brunak, Søren, 2019, In : Genome Biology. 20, 1, 4 p., 164.

    Research output: Contribution to journalLetterResearchpeer-review

  6. Published
  7. Published

    Heterogeneity in the perirenal region of humans suggests presence of dormant brown adipose tissue that contains brown fat precursor cells

    Jespersen, N. Z., Feizi, A., Andersen, E. S., Heywood, S., Hattel, H. B., Daugaard, S., Peijs, Lone, Bagi, P., Feldt-Rasmussen, Bo, Schultz, H. S., Hansen, N. S., Krogh-Madsen, Rikke, Pedersen, Bente Klarlund, Petrovic, N., Nielsen, S. & Schéele, Camilla Charlotte, 2019, In : Molecular Metabolism. 24, p. 30-43 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Estimating heritability and genetic correlations from large health datasets in the absence of genetic data

    Jia, G., Li, Y., Zhang, H., Chattopadhyay, I., Jensen, A. B., Blair, D. R., Davis, L., Robinson, P. N., Dahlen, T., Brunak, Søren, Benson, M., Edgren, G., Cox, N. J., Gao, X. & Rzhetsky, A., 2019, In : Nature Communications. 10, 11 p., 5508.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    CoCoScore: Context-aware co-occurrence scoring for text mining applications using distant supervision

    Junge, A. & Jensen, Lars Juhl, 2019, In : Bioinformatics. 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Comorbidity landscape of the Danish patient population affected by chromosome abnormalities

    Jørgensen, Isabella Friis, Russo, Francesco, Jensen, A. B., Westergaard, David, zmw894, zmw894, Hjaltelin, Jessica Xin, Brunak, Søren & Belling, Kirstine G, 2019, In : Genetics In Medicine. 21, 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Prediction of pancreatic fat and analysis of its determining factors using multi-omics datasets: an IMI DIRECTstudy

    Karaderi, Tugce, Mazzoni, Gianluca, Brorsson, Caroline Anna, Westergaard, David, Banasik, Karina, Koivula, R., Thomas, L., Bell, J., Franks, P., Pearson, E. & Brunak, Søren, 2019, In : Diabetologia. 62, p. S166-S166

    Research output: Contribution to journalConference abstract in journalResearch

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