CPR Seminar by Frank Uhlmann – University of Copenhagen

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CPR > Events > 2017 > Frank Uhlmann

CPR Seminar by Frank Uhlmann

Research seminar by Frank Uhlmann, The Francis Crick Institute, London, UK.

Title of the seminar: "Chromatin and Chromosomes, the Role and Function of SMC Complexes".

Frank Uhlmann heads the Chromosome Segregation Laboratory. Aneuploidy, i.e. missing or supernumerary chromosomes, is a hallmark of malignant tumour progression. A large number of genes that orchestrate faithful chromosome segregation during mitotic cell divisions are tumour suppressors or turn into potent oncogenes if misregulated.

The aim of the Chromosome Segregation Laboratory is to investigate cellular mechanisms that safeguard accurate chromosome segregation. In particular, we are investigating the contribution of structural chromosomal proteins to sister chromatid cohesion and chromosome condensation, essential processes that ensure faithful segregation of the centimetre-long chromosomal DNA molecules within micrometre-sized cells. A second topic of our research is the regulation of ordered mitotic progression by the cell division cycle machinery.

Read more about Frank Uhlmann's research here.

Host: Jakob Nilsson.

All are welcome. Registration is not necessary.